• Proceedings of the KIEE Conference
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• 1999.07g
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• pp.2866-2868
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• 1999

S/W 시스템을 개발하여 테스트한 후 발행시기를 결정함에 있어서 그동안의 비용-신뢰도를 동시에 고려하여 최적발행시기를 결정하고자 하는 연구결과가 얼마나 현실적으로 합리적이고 타당한가를 고찰하고자 한다. 연구방법으로서는 일반적인 비용-신뢰도 최적발행에 대한 기존의 관련논문을 중심으로 제시된 연구방법들에 대해서 연구해보고. 특히 그 최적발행정책의 한계성에 대해서 중점적으로 연구하고자 한다.

• YAKHAK HOEJI
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• v.42 no.2
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• pp.187-195
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• 1998

In order to ameliorate disadvantages of buccal ointments and mucoadhesive tablets used for the treatment of aphthosis, a thin mucoadhesive patch containing triamcinolone acetoni de was designed and evaluated for the pharmaceutical properties. The adhesive gel layer consisting of Noveon AA-1, hydroxypropylcellulose-M and ethylcellulose N 100, and the protective gel layer of ethylcellulose N 100, Eudragit RSPO and castor oil have been formulated and various properties such as viscosity of drug gel layer, thickness, in vitro adhesion time, adhesive strength, surface pH, content uniformity and drug release are tested. The mean viscosity of drug-containing gel layer was found to increase with increasing amount of Noveon OAA-1 or hydroxypropylcellulose-M. The optimum formulation showed the thickness of 171 ${\mu}$m, surface pH of 4.6, in vitro adhesion time of 8 hours and adhesive strength of 272.7g/sheet. The drug content of each patch was relatively homogeneous with the value of 273${\pm}$6.77g. Drug release study showed that compared to mucoadhesive tablet, the patch showed a faster drug release. Drug release was delayed by hydroxypropylcellulose-M, but not by ethylcellulose N 100. The patches prepared were nonirritant and the muco adhesion was better than the commercial product (AftachR) on the market. Based on these results, this mucoadhesive patch is expected to be an effective dosage form for the treatment of aphthosis.

• YAKHAK HOEJI
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• v.33 no.3
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• pp.191-202
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• 1989

Indomethacin, a non-steroidal antiinflammatory drug inducing gastric irritation, was microencapsulated using pectin-gelatin complex coacervation method. Optimum conditions for microencapsulation and dissolution characteristics of the microcapsules were studied. The optimum pH and pectin-gelatin ratio for microencapsulation were 3.8 and 1:2 respectively. As concentration of colloid solution increased, wall thickness of microcapsules were increased. The dissolution rate of Indomethacin-pectin-gelatin microcapsules prepared by 1.5% and 2% colloid solution were similar but slower than that of Indomethacin-pectin-gelatin microcapsules prepared by 1% colloid solution. The 50% release time ($T_{50%}$) of Indomethacin-pectin-gelatin microcapsules prepared by 1%, 1.5% and 2% colloid solutions were 3 min, 5 min, and 6 min respectively while that of Indomethacin powder was 50 min.

• Journal of Information Technology Applications and Management
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• v.13 no.4
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• pp.1-12
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• 2006

Many software reliability growth models(SRGM) have been proposed since the software reliability issue was raised in 1972. The technology to estimate and grow the reliability of developing S/W to target value during testing phase were developed using them. Most of these propositions assumed the S/W debugging testing efforts be constant or even did not consider them. A few papers were presented as the software reliability evaluation considering the testing effort was important afterwards. The testing effort forms which have been presented by this kind of papers were exponential, Rayleigh, Weibull, or logistic functions, and one of these 4 types was used as a testing effort function depending on the S/W developing circumstances. I propose the methology to evaluate the SRGM using least square estimator and maximum likelihood estimator for those 4 functions, and then examine parameters applying actual data adopted from real field test of developing S/W.

• Journal of Environmental Science International
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• v.14 no.9
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• pp.861-871
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• 2005

This study was carried out to get more operational characteristics of Anoxic(anaerobic)-Oxic-Anoxic-Oxic $(AO)_2$ sequencing batch biofilm reactors (SBBRs) at the low TOC concentration, The operating time in anoxic (anaerobic) time to oxic time was I : I. Experiments were conducted to find the effects of the aeration time distribution on the organic matters and nutrients removal. Three lab-scale reactors were fed with synthetic wastewater based on glucose as carbon source. During studies, the operation mode was fixed. The first aeration time to the second aeration time in SBBR-I was 2 : 3, and those in SBBR-2 and SBBR-3 were I : 4 and 3 : 2, respectively. The organic removal efficiency didn't show large difference among three reactors of different aeration time distribution. However, from these study results, the optimum aeration time distribution in the first and the second aeration time for biological nutrient removal was shown as 3 : 2. The release of phosphorus was inhibited at the second non-aeration period because of the low TOC concentration and the nitrate produced by the nitrification at the first aeration period.

• Transactions of the Korean Society of Automotive Engineers
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• v.12 no.6
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• pp.60-65
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• 2004

Numerical simulations and experiments have been carried out to investigate the effect of fuel injection nozzles on the combustion and NOx formation processes in a medium-speed marine diesel engine. Spray visualization experiment was performed in the constant-volume high-pressure chamber to verify the numerical results on the spray characteristics such as spray angle and spray tip penetration. Time-resolved spray behaviors were captured by high-speed digital camera and analyzed to extract the information on the spray parameters. Spray and combustion phenomena were examined numerically using FIRE code. Wave breakup and Zeldovich models were adopted to describe the atomization characteristics and NOx formation processes. Numerical results were verified with experimental data such as cylinder pressure, heat release rate and NOx emission. Finally, the effects of fuel injection nozzles on the engine performance were investigated numerically to find the optimum nozzle parameters such as fuel injection angle, nozzle hole diameter and number of nozzle holes. From this study, the optimum fuel injection nozzle (nozzle hole diameter, 0.32 mm, number of nozzle holes, 8 and fuel injection angle, $148^{\circ}$) was selected to reduce both the fuel consumption and NOx emission. The reason for this selection could be explained from the highest fuel-air mixing in the early phase of injection due to the longest spray tip penetration and the highest heat release rate after $19^{\circ}$ ATDC due to the increased injection duration.

• Food Science and Biotechnology
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• v.17 no.2
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• pp.408-412
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• 2008

Determining the elution of water-soluble substances from herbal teas is an important factor in their efficient use in terms of taste, perfume, and content of health-related components. The antioxidant activity and content of catechins in commercial Chrysanthemum indicum (gamguk) teas were determined for optimum elution conditions. The water extract of gamguk teas did not differ significantly in yield compared to methanol extracts and showed stronger antioxidant activity. Catechin contents in gamguk teas were 8-18% of the extracts when individual peaks in high-performance liquid chromatography analysis were compared to standard catechin peaks. Gamguk teas exhibited faster release of antioxidants, and the antioxidant activity was positively correlated with the thermal treatments. Gukhwacha (GC) was the best tea for rapid release (30 sec) of antioxidants with the $50^{\circ}C$ treatment, whereas antioxidants in other teas were relatively slower released.

• Journal of Korean Institute of Industrial Engineers
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• v.25 no.1
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• pp.47-55
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• 1999

This paper develops an efficient heuristic algorithm for scheduling workforce level that can accommodate all the requested maintenance jobs. Each job has its own release and due dates as well as man-day requirement, and must be scheduled in a non-interrupted time interval, namely, without preemption. Duration of each job is not fixed, but to be determined within given specific range. The objective is to minimize workforce level to complete all the requested maintenance jobs. We show that the problem can be seen as a variant of the two-dimensional bin-packing problem with some additional constraints. A non-linear mixed integer programming model for the problem is developed, and an efficient heuristic algorithm based on bin-packing algorithms is proposed. In order to evaluate goodness of the solution obtained from the proposed algorithm, a scheme for getting a good lower bound for the optimum solution is presented and analyzed. The computational experiment shows that the proposed algorithm performs quite satisfactorily.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.37 no.6
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• pp.499-505
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• 1992

This experiment was carried out to find out the optimum application method of slow-release fertilizer under different soil textures, clay loam(Deogpyeong series), sandy loam (Gangseo series) in the southern region(Milyang, Kyeongnam) of Korea. The fertilizers used were Chosun slow-release fertilizer(silicate latex coated fertilizer: N-P$_2$O$_{5}$-K$_2$O=18-12-13) and Meister 15 (thermoplastic resin coated fertilizer : N-P$_2$O$_{5}$-K$_2$O=14-14-14). The two whole basal application methods such as side band placement at transplanting time of rice plant(cv.Donghaebyeo) and incorporation with soil as basal were tested. The released amount of ammonium nitrogen from the soils for 4 days submerged was 95ppm in sandy loam and 60ppm in clay loam. The greenish degree of rice leaf was higher at the whole plow layer placement method than the others. The nitrogen efficiencies of the fertilizers were Meister 15 > convention > Chosun in order and between the application methods were similiar. The growth status was better at the whole plow layer placement application method of Meister 15 regardless of soils and seedling ages. The ripening ratio was increased at slow-release fertilizer application, and between application methods, whole plow layer placement was lower because of lodging damage. The yield in clay loam soil showed a significant difference between the ferilizers, but there were slight differences between the application methods and fertilizers in sandy loam soil. As a result, the slow-release fertilizer, Meister 15, applied at the whole layer showed a good rice growth and seemed a plausible fertilizing method.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.4
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• pp.452-457
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• 1999

Algicidal bacteria were isolated from the mud of south coastal sea of Korean peninsula and screened to evaluate algicidal activity on Cochlodinium polykrikoides. The optimum condition for the development of highest algicidal activity was determined, The optimum sodium chloride concentration for algicidal activity of isolated algicidal bacteria was $3\%$. The optimum temperature, pH and culture time for the highest algicidal activity were $30^{\circ}C$, pH 7 and above 24 hr, respectively. The algicidal activity were significantly increased at the stationary phase of the cell growth and continuously increased up to maximum at the death phase, probably due to the release of algicidal substance by cell Iysis. The effect of zinc ion addition on algicidal activity, was observed and indicated that the substance requires zinc for its activity. The candidate for the algicidal substance may be $\alpha$-mannosidase.