• The Korean Journal of Applied Statistics
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• v.6 no.1
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• pp.145-162
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• 1993

We review sampling schemes on successive occasions with partial replacement of units and propose a Rao-Hartley-Cochran(RHC) type's sampling scheme over two successive occasions with probability proportionate to observations on the previous occasion. For comparison of the reviewed and proposed sampling schemes, optimal estimator of population mean on second occasion and its variance are derived. The relative efficiency of the proposed sampling scheme is compared with other equal and unequal probability sampling scheme by theoretical and numerical simulation study. For simulation study, three artificial populations are generated by a time series model. It is observed that RHC type's sampling scheme has small variance and deviation in general.

• Journal of Dental Rehabilitation and Applied Science
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• v.19 no.1
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• pp.43-48
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• 2003

During the past several years, significant advances have occurred in the utilization of osseointegrated implants for the treatment of partially edentulous patients. One of the biggest purposes for treating of these patients is the high demand for improved esthetics, especially in the anterior region. For this esthetics, the new trend in dental implants is the immediate placement and immediate superstructure fabrication. The refined surgical technique, the skillful soft tissue management, and the proper prosthetic coordination are the main factors to achieve natural looking of implant supported prosthesis. The customized provisional restoration and the customized impression coping are recommended for the optimal peri-implant soft tissue contour. The basic concept of Frialit 2 system was the immediate replacement of a tooth with root-analog fixture after extraction. This system guarantees an ideal result in function and esthetics. The ceramic abutment system offers improved quality in the respect of esthetics, fitness, translucency, and biocompatibility. In this clinical report, the final restoration made with IPS Empress 2 crown on the CeraBase abutmen of Frialit 2 system allowed the reproduction of the natural vitality of tooth and adjacent gingiva.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.325-328
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• 2008

Recently increasing interest in high-rise building around the world for more than 100 floor, the trend is the increasing use of high-strength and high-flowable concrete so as of productivity improvements and cost savings to improve the performance of the early strength development. This study is to reach the optimal combination by reviewing the performance of high-rise building which is required. The results, lower the ratio of W/B was an increase in compressive strength and early strength in the use of admixture decreased in the combination of higher replacement ratio of admixture.

• BMB Reports
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• v.41 no.1
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• pp.72-78
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• 2008

Human NeuNAc-9-P synthase is a two-domain protein with ability to synthesize both NeuNAc-9-P and KDN-9-P. Its mouse counterpart differs by only 20 out of 359 amino acids but does not produce KDN-9-P. By replacing the AFL domain of the human NeuNAc-9-P synthase which accommodates 12 of these differences, with the mouse AFL domain we examined its importance for the secondary KDN-9-P synthetic activity. The chimeric protein retained almost half of the ability of the human enzyme for KDN-9-P synthesis while the NeuNAc-9-P production was reduced to less than 10%. Data from the homology modeling and the effect of divalent ions and temperature on the enzyme activities suggest conformational differences between the human and mouse AFL domains that alter the shape of the cavity accommodating the substrates. Therefore, although the AFL domain itself does not define the ability of the human enzyme for KDN-9-P synthesis, it is important for both activities by aiding optimal positioning of the substrates.

• Journal of Institute of Control, Robotics and Systems
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• v.7 no.6
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• pp.523-531
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• 2001

This paper describes and automatic mirror adjustment system that rotates a pair of side mirrors and the room mirror of a car to the optimal position for a driver by using the locating of the driver\`s pupils. A stereo vision system measures 3D coordinates of a pair pupils by analyzing the input images of stereo B/W CCD cameras mounted on the instrument panel. this system determines the position angle of each mir-ror on the basis of information about the location of the pupils and rotates each mirror to the appropriate po-sition by mirror actuators. The vision system can detect the driver\`s pupils regardless of whether it is day-time or nighttime by virtue of an infrared light source. information about the pair of nostrils in used to im- prove the correctness of pupil detection. This system can adjust side mirrors and the room mirror automati- cally and rapidly by a simple interface regardless of driver replacement of driver\`s posture. Experiment has shown this to be a new mirror adjustment system that can make up for the weak points of previous mirror adjustment systems.

• Proceedings of the Korea Concrete Institute Conference
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• 2000.04a
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• pp.339-342
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• 2000

Recently, the importance of the conutermeasures for waste materials has pointed out. Waste glass is also one to waste materials used for the recycling in construction sites. The crushed waste glass has been used to make a glass polymer composite that can be applied for sewer, storm drain pipe and interlocking block, etc. In this study, the crushed waste glass is explored with the possibility of recycling it, as a substitute for fine aggregates. The prepose of this investigation is to improve the strengths and acid resistance of the UP mortars using crushed waste glass. The UP mortars are prepare with blast furnace slag fly ash filler. the UP-fine aggregate ratios the crushed waste glass replacements for fine aggregate are tested strengths before and after immersion(H (아래첨자2)SO(아래첨자4) 10%), weight change and acid resistance are also tested. From the test results, the relative strength or UP mortars using fly ash as filler are found to be somewhat superior to that of the UP mortars using blast furnace as filler, And a UP mortar with fly ash as a filler, a UP-fine aggregate ratio of 15% and a waste glass replacement if 50% for fine aggregate is recommended as optimal mix proportion of UP mortar using crushed waste glass. Accordingly, it is enough to assure the use of the crushed waare glass as an aggregate for the production of UP mortar.

• Journal of the Korean Geosynthetics Society
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• v.8 no.2
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• pp.1-9
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• 2009

When some structures are constructed over the sanitary landfill, the waste should be treated by means of replacement and other ways. Otherwise, various problems like a ground contamination, settlement, reduction of bearing capacity and others may be generated. To find out the optimal method of treatment, the properties of the ground have to be inspected. In this study, the preliminary investigation was conducted to find out the characteristic of this site which is considered as insanitary waste landfill. Furthermore, the shape and the amount of the waste was investigated by subsurface investigation like a boring and sampling methods. In addition, the degree of ground contamination and disposal method of refuse was examined.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.32 no.12
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• pp.1132-1139
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• 2008

The aim of this study is to apply shape optimization technique for the repair of aging airframe components, which may extend fatigue life substantially. Free-form optimum shapes of a cracked part to be reworked or replaced are investigated with the objective to minimize the peak local stress concentration or fatigue-damage. Iterative non-gradient method, which is based on an analogy with biological growth, is employed by incorporating the robust optimization method to take account of the stochastic nature of the loading conditions. Numerical examples of optimal hole shape in a flat plate are presented to validate the proposed method. The method is then applied to determine the reworked or replacement shape for the repair of a cracked rib in the rear assembly wing body of aircraft.

• Journal of Energy Engineering
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• v.24 no.2
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• pp.45-50
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• 2015

In Korea ranking sixth out of The world's greenhouse gas emissions, all Korean public buildings have to implement obligatorily renewable energy systems for energy production to reduce the greenhouse gas emissions from the energy consumed in operation, maintenance and management of buildings. The optimum combination and application rates for each energy source emerge from analyzing the trend of previous studies and the energy consumption is simulated by using a dynamic energy simulation program and the initial investment costs, the energy costs, the maintenance costs, the replacement costs emerge based on the calculated result. The result show that the total life cycle cost of 100% gerthermal is the lowest with \ 2,105,974,344 on the analysis results.

• Biomolecules & Therapeutics
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• v.17 no.1
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• pp.104-110
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• 2009

Phenylketonuria (PKU) is an inherited metabolic disorder caused by mutations in the phenylalanine catabolic enzyme, phenylalanine hydroxylase (PAH). The use of phenylalanine ammonia-lase (PAL) by oral and parenteral routes as a therapeutic drug for PKU has been severely limited due to inactivation by intestinal proteolysis and immune reactions. PEGylation was applied to PAL to reduce the degrees of antigenicity and proteolytic inactivation. Kinetic experiments with native PAL and pegylated PALs were performed, and pH stability, temperature stability, and protease susceptibility were evaluated. Enzyme linked immunosorbent assay (ELISA) was carried out to measure the immune complex between pegylated PALs and antiserum that had been extracted from a PAL-immunized mouse. Pegylated PAL, especially branched pegylated PAL (10 kDa, 1:32), was more active for phenylalanine and more stable in pancreatic proteases than native PAL. Native PAL was optimal at pH 8.5, corresponding to the average pH range of the small intestine; the same finding was noted for pegylated PALs. All linear and branched pegylated PALs had low reactivity with mouse antiserum, especially the 1:16 formulation with linear 5-kDa PEG and the 1:32 formulation with branched 10-kDa PEG. Therefore, we suggest the 1:32 formulation with branched 10-kDa PEG as the most promising formulation for enzyme replacement therapy.