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Receptor binding motif surrounding sites in the Spike 1 protein of infectious bronchitis virus have high susceptibility to mutation related to selective pressure

  • Seung-Min Hong;Seung-Ji Kim;Se-Hee An;Jiye Kim;Eun-Jin Ha;Howon Kim;Hyuk-Joon Kwon;Kang-Seuk Choi
    • Journal of Veterinary Science
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    • v.24 no.4
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    • pp.51.1-51.17
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    • 2023
  • Background: To date, various genotypes of infectious bronchitis virus (IBV) have co-circulated and in Korea, GI-15 and GI-19 lineages were prevailing. The spike protein, particularly S1 subunit, is responsible for receptor binding, contains hypervariable regions and is also responsible for the emerging of novel variants. Objective: This study aims to investigate the putative major amino acid substitutions for the variants in GI-19. Methods: The S1 sequence data of IBV isolated from 1986 to 2021 in Korea (n = 188) were analyzed. Sequence alignments were carried out using Multiple alignment using Fast Fourier Transform of Geneious prime. The phylogenetic tree was generated using MEGA-11 (ver. 11.0.10) and Bayesian analysis was performed by BEAST v1.10.4. Selective pressure was analyzed via online server Datamonkey. Highlights and visualization of putative critical amino acid were conducted by using PyMol software (version 2.3). Results: Most (93.5%) belonged to the GI-19 lineage in Korea, and the GI-19 lineage was further divided into seven subgroups: KM91-like (Clade A and B), K40/09-like, QX-like (I-IV). Positive selection was identified at nine and six residues in S1 for KM91-like and QX-like IBVs, respectively. In addition, several positive selection sites of S1-NTD were indicated to have mutations at common locations even when new clades were generated. They were all located on the lateral surface of the quaternary structure of the S1 subunits in close proximity to the receptor-binding motif (RBM), putative RBM motif and neutralizing antigenic sites in S1. Conclusions: Our results suggest RBM surrounding sites in the S1 subunit of IBV are highly susceptible to mutation by selective pressure during evolution.

Investigating Occupational Therapy Students' Awareness of Developmental Rehabilitation Services and the Accreditation of Sensory Developmental Rehabilitation Service Providers (작업치료 전공 학생들의 발달재활서비스 및 감각발달재활서비스 제공인력 자격인정에 대한 인식도 조사)

  • Sung, La-Yun;Chang, Moon-Young
    • The Journal of Korean Academy of Sensory Integration
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    • v.21 no.2
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    • pp.35-44
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    • 2023
  • Objective : This study sought to explore occupational therapy students' awareness of Developmental Rehabilitation Services (DRSs) and the certification of Sensory Developmental Rehabilitation Service Providers (SDRSPs). Moreover, it also aimed to examine the differences in students' awareness based on general characteristics. The findings were intended to provide a foundation for research on sensory developmental rehabilitation. Methods : An online survey was conducted among 199 occupational therapy students nationwide from October 4 to November 5, 2022. Frequency analysis was used to assess the general characteristics and additional items. Both descriptive statistics and frequency analysis were employed to assess the students' awareness of DRSs and SDRSP certification. Any differences in the students' awareness based on their general characteristics were examined using t-tests and an analysis of variance. Results : The students' awareness of DRSs was moderate (4.50 ± 2.40), while their awareness of SDRSP certification was also moderate (4.22 ± 2.55). The awareness of DRSs varied significantly based on the students' academic year and child-related practice experience. Similarly, the awareness of SDRSP certification differed significantly based on the students' academic program, academic year, recognition by the related department, and child-related practice experience. Conclusion : The occupational therapy students expressed a strong intention to provide DRSs and become certified as SDRSPs. However, their awareness levels were moderate. These findings emphasize the importance of educational efforts and the provision of relevant information about DRSs and SDRSP certification in universities to foster the development of competent SDRSPs.

The impact of ESG management on the Corporate Performance of Shipping and Logistics Companies: The mediating effect of Organizational Culture (ESG 경영이 해운물류기업의 경영성과에 미치는 영향: 조직문화의 매개효과)

  • Kim, Young-Soo
    • Journal of Korea Port Economic Association
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    • v.39 no.3
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    • pp.75-90
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    • 2023
  • This study aims to examine the impact of ESG management on management performance based on the type of organizational culture in Korean shipping and logistics companies. An online survey was conducted among shipping lines (regular and irregular) and general logistics companies with sales of more than 500 billion won that are implementing ESG management. A total of 183 copies were returned, and PLS structural equation analysis was conducted using the Smart PLS 4.0 program. The results of the study are as follows First. Governance management activities have a significant effect on business performance, social management activities have a significant effect on innovation culture, governance management activities have a significant effect on innovation culture, environmental management activities have a significant effect on hierarchical culture, and governance management activities have a significant effect on hierarchical culture. Contributions of this study First, this study analyzes the impact of ESG management activities on management performance of Korean shipping and logistics companies. Second, this study collected data through a questionnaire survey. The data were analyzed to determine the effect of ESG management activities on management performance. The data was analyzed to determine the level of ESG-related activities and business performance of companies and used to analyze the correlation between ESG management activities and business performance. Third, the results of the study suggest that companies can recognize that ESG management can help them improve their business performance. This can help companies build sustainable management strategies and further strengthen their management orientation to consider ESG factors.

Effect of Busan Yacht Experience Tourism on the Stress Recovery and Behavioral Intention of Tourists (해양 요트 체험 매력 속성이 스트레스 회복과 행동 의도에 미치는 영향 연구)

  • Park, Seung-Hwa;Jeong, Chul
    • Journal of Korea Port Economic Association
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    • v.39 no.2
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    • pp.111-128
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    • 2023
  • Due to the coronavirus pandemic, interest in outdoor leisure activities is growing. Among outdoor leisure activities, marine sports can be seen as having good conditions to enjoy in Korea. In the case of yachting among marine sports, a number of yacht experience programs have recently been operated centered on Gwanganli and Suyeong Bay in Busan. This yacht experience is an attractive tourism product that can be enjoyed casually, and can bring stress relief to many users. This study tried to verify the effect of the attractiveness of the yacht experience on the stress recovery based on the tourists' experiences using the yacht experience tour. In addition, we tried to verify the intention of revisiting the yacht experience or sharing it with others through SNS through this stress recovery. In addition, as a moderator variable, the difference between the MZ generation and other generations, which use SNS more actively than other generations, was presented and its significance was verified. The survey of this study was conducted online for tourists who experienced yacht experience in Busan. As a result of the analysis, among the attractive factors of the yacht experience, the program, landscape, facilities and service was found to have a significant influence on the users' stress recovery, and satisfaction through stress recovery had a significant effect on the intention to revisit and to share the SNS. In the verification of the moderating effect according to age, a generational difference in revisit intention between the MZ generation and other generations was confirmed. Through this study, it was suggested that various programs of yacht experience should be developed to induce users to revisit, and various marketing using SNS should be carried out.

A Study on Perceptions of Users for Establishing Mid-to Long Term Development Plan for Public Libraries in Dobong-gu (도봉구 공공도서관 중장기 발전계획 수립을 위한 지역주민 인식 연구)

  • Su-Young Lee;Ji-Ann Yang;Jae-Woo Nam;Min Sun Song
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.34 no.4
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    • pp.183-205
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    • 2023
  • This study was conducted to identify the operation status of Dobong-gu public libraries in order to establish a mid- to long-term development plan for Dobong-gu libraries, and to analyze local residents' perceptions of libraries by factors through user surveys to suggest specific development plans for Dobong-gu libraries. Overall, the satisfaction level of Dobong-gu residents with library services was found to be high, and all libraries were analyzed to be providing high-quality services. From this, the following operational strategies for the mid- to long-term development plan of Dobong-gu public libraries can be derived. First, libraries need to continue to collect and provide books that meet the quantitative and qualitative levels to satisfy the needs of the community and users. Electronic and online materials, including e-books and audiobooks, as well as subject-specific materials should be expanded to provide relevant programs. Second, although Dobong-gu is an aging city, a wide range of age live there, so there is a need to promote communication and understanding between generations and promote integration of the community through a generational empathy program. Third, it is necessary to remodel and improve the space of aging libraries by organizing library facilities and environments into open spaces and creating makerspaces and multicultural spaces for direct experience and practice, reflecting the latest trends in library space organization.

The Effect of Basic Learning Ability Improvement Clinic Classes on Self-efficacy, Immersion, and Major Satisfaction in College Students

  • Jung-Oh Lee;Gyeoung-Ran Moon
    • Journal of the Korea Society of Computer and Information
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    • v.28 no.11
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    • pp.135-145
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    • 2023
  • Due to the decrease in the school-age population, the number of freshmen at local college who lack basic learning skills is increasing. Thus, C college has been running a basic learning ability improvement clinic program. This paper is a case study that investigates the effect of basic learning ability improvement clinic programs on major class immersion, efficacy, and major class satisfaction. In 2022, a total of 459 students were surveyed, including 238 students who participated in online and offline classes for basic learning ability improvement clinics and 221 students who did not participate in classes. Data processing was performed using SPSS Ver. 26.0 was used. The results of this study are as follows. First, among the sub-factors of academic self-efficacy, the group participating in the basic learning ability improvement clinic showed significant differences in task difficulty preference and confidence. Second, the class participation group showed a significant difference in learning immersion in major classes. Third, the class participation group showed significant differences in all sub-factors of major satisfaction. In conclusion, it was found that the basic learning ability improvement clinic class had a significant effect on academic self-efficacy, learning immersion, and major satisfaction.

A study on the relationship between college students' self-differentiation and marriage outlook (대학생의 자아분화와 결혼관의 관계연구)

  • Ri-a Lee;Won-Sun Lim
    • Industry Promotion Research
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    • v.9 no.1
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    • pp.179-187
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    • 2024
  • This study aims to develop policies and programs to improve self-differentiation that will have an impact on establishing a positive view of marriage among college students by examining and confirming the impact of college students' self-differentiation on their views on marriage among college students in early adulthood. This is an attempted research study. For this purpose, a self-report online survey was conducted and analyzed among 204 college students attending a university in northern Gyeonggi Province. The analysis method used SPSS 25.0 program to calculate internal consistency, frequency analysis to identify the general characteristics of the research subject, descriptive statistical analysis to determine the level of the research variable, and differences in research variables according to the characteristics of the research subject. To find out, an independent samples t-test, analysis of variance, and post hoc test were conducted, and analysis using SPSS Process Macro was conducted to verify the mediation effect. The results of the analysis showed a positive (+) correlation between self-differentiation and views on marriage, which suggests that self-differentiation has a significant impact on establishing a positive view on marriage, and for this purpose, it is necessary to establish a positive view on marriage among college students. To this end, we aimed to provide basic data to support education for healthy families through national policy.

The relationship between of snack habits, oral health behavior and oral health status in middle and high school students (중고생들의 식습관 및 구강보건행태와 구강건강 상태의 관련성 연구)

  • Hyun-Kyung Yun;Jong-Hwa Lee;Da-Hye Hwang
    • Journal of Korean Dental Hygiene Science
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    • v.6 no.2
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    • pp.1-12
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    • 2023
  • Objectives: This study attempted to identify the eating habits and oral health behaviors of Korean teenagers, studying their relationship with oral health status. The findings serve as fundamental data to enhance proper eating habits and oral health-related projects, ultimately improving teenagers' oral health. Methods: It was analyzed through the original data of the 16th (2020) online survey of youth health behavior in Korea, Frequency analysis, complex sample cross-analysis, complex sample logistic regression analysis were conducted using the SPSSwin 21.0 program. Results: As a result of the study, was associated with the consumption of all sweet drinks, fast food intake, and the frequency of daily brushing over the past 7 days Teeth pain is noted with the consumption of soda, sweet drinks, fast food, and the frequency of daily brushing over the past 7 days. Gum bleeding is noted with the consumption of sweetened products, fast food intake, and the frequency of daily brushing over the past 7 days. Conclusions: Eating habits and oral health behaviors should be considered for the oral health management of middle and high school students. Specific measures should be sought to provide proper dietary education and systematic oral health education to improve the oral health of middle and high school students.

A study of factors influencing sunscreen use among Koreans: application of the Health Belief Model (HBM) (한국인의 자외선차단제 사용에 영향을 미치는 요인 연구 : 건강신념모델(HBM)의 적용)

  • Ji-Won Kim;Seunghee Bae
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.2
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    • pp.472-483
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    • 2024
  • This study evaluated the attitudes of the Korean population towards sunscreen use through the Health Belief Model (HBM) construct and investigated the psychological factors that influence sunscreen use. For this purpose, an online survey was conducted from 1 November 2023 to 1 January 2024, and a total of 303 participants were collected. The collected data were analysed using SPSS v. 25.0 programme using Cronbach's 𝛼, frequency analysis, descriptive statistics, correlation analysis, independent samples t-test, one way ANOVA, Scheffe's test, and multiple regression analysis. The results of the study showed that the mean score of sunscreen use was 3.26±1.384 out of 5, and there was a significant correlation between the variables of the health belief model and sunscreen use (p<.01). Gender, age, and skin colour were also associated with each variable, with women, the elderly, and those with lighter skin tending to be more proactive in sun protection. Multiple regression analyses revealed that self-efficacy (𝛽=.629, p<.001) and perceived vulnerability (𝛽=.139, p<.001), sub-factors of the Health Belief Model, had a statistically significant positive effect on sunscreen use, while perceived barriers (𝛽=-.261, p<.001) had a statistically significant negative effect on sunscreen use. These results may have important theoretical implications for the development and implementation of educational programmes to promote sunscreen use by providing insight into the psychosocial factors that influence sun protection.

Effects of Positive Psychological Capital, Job Crafting and Nursing Work Environment on Job Satisfaction of Clinical Nurses (임상간호사의 긍정심리자본, 잡 크래프팅과 간호근무환경이 직무만족에 미치는 영향)

  • Kyung Ae Park;Ja-Sook Kim
    • Journal of Industrial Convergence
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    • v.22 no.3
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    • pp.67-78
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    • 2024
  • The purpose of this study is to identify the factors affecting job satisfaction by examining the positive psychological capital, job crafting, and nursing work environment of clinical nurses, and to provide foundational data necessary to devise strategies for enhancing job satisfaction. Data were collected online from 208 clinical nurses working in three comprehensive hospitals located in J city from March 15 to March 30, 2023. Data were analyzed using the SPSS/WIN 26.0 program. The influencing factors on subjects' job satisfaction were marital status, education level, salary satisfaction, workload, clinical experience, positive psychological capital, job crafting, and nursing work environment. A hierarchical regression analysis following the order of general characteristics, positive psychological capital, nursing work environment, and job crafting identified nursing work environment (𝛽=.37, p<.001), job crafting (𝛽=.35, p<.001), positive psychological capital (𝛽=.33, p<.001), education level (𝛽=.09, p=.014) and salary satisfaction (𝛽=.09, p=.015) as the influencing factors of job satisfaction, in which the explanatory power for the final model was 78%. Based on the results of this study, it is suggested to develop and verify the effectiveness of programs to improve the positive psychological capital and job crafting of clinical nurses.