• Title/Summary/Keyword: One-pot

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One-pot Synthesis of Dihydropyrimidinones Using Polyoxometalate Tri-supported Transition Metal Complexes (Polyoxometalate Tri-supported Transition Metal Complexes를 이용한 Dihydropyrimidinones의 one-pot 합성)

  • Fazaeli, Razieh;Aliyan, Hamid;Mohammadifar, Foroogh;Zamani, Amir Abbas;Bagi, Mohammad Javad
    • Journal of the Korean Chemical Society
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    • v.55 no.4
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    • pp.666-672
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    • 2011
  • The catalytic activity of an inorganic-organic complex with a vanadium-substituted polyoxometalate 1, formulated as [Cu(2,2'-bipy)]$[Cu(2,2'-bipy)_2]_2[PMo_8V_6O_{42}]{\cdot}1.5H_2O$ was studied in the Biginelli reactions. The obtained results showed that, in the one-pot synthesis of dihydropyrimidinones, the turnover frequencies (TOF) for the [Cu(2,2'-bipy)]$[Cu(2,2'-bipy)_2]_2[PMo_8V_6O_{42}]{\cdot}1.5H_2O$ catalyst were higher than the $H_3PMo_{12}O_{40}$ catalyst.

Improved One-pot Regioselective Synthesis of 3,7-Diarylpyrazolo[1,5-α]pyrimidines and Their CB1R Activity (3,7-Diarylpyrazolo[1,5-α]pyrimidines의 개선된 One-pot Regioselective 합성과 CB1R 활성)

  • Hong, Yong Deog;Byoun, Kyoung Hee;Park, Miyoung;Park, Jun Seong;Shin, Song Seok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.2
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    • pp.143-150
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    • 2015
  • This study demonstrates an effective one-pot regioselective synthesis of 3,7-diarylpyrazolo [1,5-${\alpha}$]pyrimidines. Moreover, the derivatives obtained were effective CB1R antagonists. These pyrazolo [1,5-${\alpha}$]pyrimidines with diaryl groups at the 3,7-positions are potential pharmacophores for CB1R candidates.

One-pot Enzymatic Synthesis of UDP-D-glucose from UMP and Glucose-1-phosphate Using an ATP Regeneration System

  • Lee, Hei-Chan;Lee, Seung-Don;Sohng, Jae-Kyung;Liou, Kwang-Kyoung
    • BMB Reports
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    • v.37 no.4
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    • pp.503-506
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    • 2004
  • Glucose-1-phosphate uridylyltransferase from E. coli K12 was used to convert uridine-5'-triphosphate and glucose-1-phosphate to UDP-D-glucose. The conversion was efficient and completed within 5 minutes under the employed conditions. In addition, thymidine-5'-monophosphate kinase and acetate kinase were proven to be non-specific, converting udridine-5'-monophosphate to uridine-5'-triphosphate with 55% conversion after 6 h, which was much slower than the production of TTP under the same conditions (complete conversion within one hour). Since these two reactions could proceed under the same conditions, a one-pot synthesis of UDP-D-glucose with ATP regeneration was designed from easily available starting materials, and conversion up to 40% by HPLC peak integration was achieved given a reaction time of 4 h.

Environmental Impact and Water Foot Print Assessment of Pot Bearing Using Life Cycle Assessment (LCA) (LCA를 이용한 교량용 포트받침 환경영향 및 물발자국 분석)

  • Park, Jihyung;Wie, Daehyung;Ko, Kwanghoon;Hwang, Yongwoo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.38 no.6
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    • pp.851-857
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    • 2018
  • In this research, LCA analysis of the manufacturing process of pot bearing for fixed, movable in all directions, movable in one direction was carried out to analyze the environmental load using the LCA methodology. Especially, the water footprint that has been and issue in recent years was analyzed. As a result of LCA, it was analyzed that the contribution of the plate was more than 64.2% in all of the six impact categories in the case of fixed pot bearing base, and more than 94% in the category of resource depletion and photochemical oxidant creation. In the case of all direction pot bearing and one direction pot bearing, the contribution of PTFE was the highest in the global warming and stratospheric ozone depletion, and the contribution by the plate was higher in the other impact categories. The water footprint of each type of pot bearing was analyzed as $22.4m^3\;H_2O\;eq/kg$ for one direction pot bearing, $17.1m^3\;H_2O\;eq/kg$ for fixed pot bearing, and $14.1m^3\;H_2O\;eq/kg$ for all direction pot bearing. As a result of life cycle analysis, the contribution of water use in manufacturing was more than 65% in all three types. The results of this study can be used as basic data for decision making in construction method and material selection of bridges in the future.

One-pot Synthesis of Hydrous MnO2 Nanowires for Selective Oxidative Transformation of Furfuryl Alcohol (Furfuryl 알코올의 선택적 산화 전환에 대한 수화 이산화망간 나노와이어의 One-pot 합성)

  • Mobina, Irshad;Choi, Bong Gill;Kim, Jung Won
    • Applied Chemistry for Engineering
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    • v.30 no.1
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    • pp.49-53
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    • 2019
  • Hydrous $MnO_2$ nanowires were easily synthesized by an one-pot synthesis with a simple hydrothermal method. As prepared hydrous $MnO_2$ nanowires were characterized with scanning emission microscopy (SEM), transmit emission microscopy (TEM), X-ray diffraction (XRD), and Brunauer-Emmett-Teller (BET). They showed a good catalytic activity with the suitable nano-size of 4-5 nm and morphology. The furfuryl alcohol was selected as a substrate and the reaction was carried out in a toluene solvent at $100^{\circ}C$ under the atmospheric pressure of oxygen. The hydrous $MnO_2$ nanowire catalyst exhibited an excellent yield of furfural with the first-rate selectivity and conversion. The catalytic performance during recycle tests was also carried out and the catalyst showed a good mechanical strength with a negligible loss in the activity over five reaction cycles.

One-Pot Homo- and Cross-Coupling Reactions of Arenediazonium Tosylate Salts for the Synthesis of Biaryls and Polyaryls

  • Vajpayee, Vaishali;Song, Young-Ho;Ahn, Jeong-Soo;Chi, Ki-Whan
    • Bulletin of the Korean Chemical Society
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    • v.32 no.spc8
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    • pp.2970-2972
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    • 2011
  • One-pot homo- and cross-coupling reactions of arenediazonium tosylate salts bearing a halogen group have been exploited for the synthesis of biaryls and polyaryls under mild conditions. $Pd(OAc)_2$ has proven to be an efficient catalyst for the successful dual transformation of diazonium salts into p-quaterphenyl (3).

A Study on Children′s Satisfaction with Food Service in Elementary Schools in Seoul Area (Baps, Soups, Pot Stews, One Course Dishes, Kimchies) (서울지역 초등학생들의 학교 급식 만족도 연구 (밥류, 국류, 찌개류, 일품요리류, 김치류))

  • 박신인;배소연
    • The Korean Journal of Food And Nutrition
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    • v.14 no.6
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    • pp.532-542
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    • 2001
  • The purpose of this study is to investigate children's satisfaction with baps, soups, pot stews, one course dishes, and kimchies provided by elementary school lunch program in Seoul area. Two hundred and thirty two children enrolled in 3 different elementary schools participated In this study through a questionnaire developed by the researchers. Conclusions drawn from the results of this study are 1) children seemed to be generally satisfied with foods provided by school lunch program : 2) it is necessary for children to control amount of food and salt and/or hot peppers depending upon their own preference; and 3) appropriate temperature of each food should be maintained by using thermos pots, and the shape of dining board needs to be improved for younger children's convenience.

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Silica Gel Promoted Mild, Efficient and Inexpensive Protocol for the Preparation of 3,4-dihydropyrano[c]chromenes (Silica Gel을 이용한 효율적인 3,4-dihydropyrano[c]chromenes의 합성)

  • Prasanna, T.S.R.;Raju, K. Mohana
    • Journal of the Korean Chemical Society
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    • v.55 no.4
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    • pp.662-665
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    • 2011
  • Highly efficient, three-component condensation of aromatic aldehyde, malononitrile and 4-hydroxycoumarin promoted by neat silica gel at room temperature is described. The method offers an excellent alternative to the synthesis of 3,4-dihydropyrano[c]chromenes. The reactions are fast and clean, and the products are obtained with good yield and purity.

One-pot synthesis of PdAu bimetallic composite nanoparticles and their catalytic activities for hydrogen peroxide generation

  • Xiao, Xiangyun;Kang, Tae-Uook;Nam, Hyobin;Bhang, Suk Ho;Lee, Seung Yong;Ahn, Jae-Pyung;Yu, Taekyung
    • Korean Journal of Chemical Engineering
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    • v.35 no.12
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    • pp.2379-2383
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    • 2018
  • We report a facile one-pot aqueous-phase synthesis of PdAu bimetallic nanoparticles with different Pd/Au ratio. The synthesis was conducted by co-reduction of Pd and Au precursor using ascorbic acid as a reducing agent and in the presence of polyallylamine hydrochloride (PAH). By high-angle annular dark field scanning transmission electron microscopy (HAADF-STEM) and energy-dispersive X-ray spectrometry (EDS) analyses, we found that the synthesized nanoparticles had an onion-like core/shell/shell/shell structure with Au-rich core, Pd-rich shell, Au-rich shell, and Pd shell, respectively. We also investigated the catalytic performance of the synthesized PdAu nanoparticles toward hydrogen peroxide generation reaction.

One-pot Synthesis of Multifunctional Mn3O4/mesoporous Silica Core/shell Nanoparticles for Biomedical Applications

  • Lee, Dong Jun;Lee, Nohyun;Lee, Ji Eun
    • Applied Chemistry for Engineering
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    • v.33 no.1
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    • pp.113-118
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    • 2022
  • Multifunctional nanomaterials based on mesoporous silica nanoparticles (MSN) and metal oxide nanocrystals are among the most promising materials for theragnosis because of their ease of modification and high biocompatibility. However, the preparation of multifunctional nanoparticles requires time-consuming multistep processes. Herein, we report a simple one-pot synthesis of multifunctional Mn3O4/mesoporous silica core/shell nanoparticles (Mn3O4@mSiO2) involving the temporal separation of core formation and shell growth. This simple procedure greatly reduces the time and effort required to prepare multifunctional nanoparticles. Despite the simplicity of the process, the properties of nanoparticles are not markedly different from those of core/shell nanoparticles synthesized by a previously reported multistep process. The Mn3O4@mSiO2 nanoparticles are biocompatible and have potential for use in optical imaging and magnetic resonance imaging.