• 제목/요약/키워드: Odd Ratio

검색결과 134건 처리시간 0.029초

Analysis of FHIT Gene Methylation in Egyptian Breast Cancer Women: Association with Clinicopathological Features

  • Zaki, Seham Mahrous;Abdel-Azeez, Hala A.;El Nagar, Mona Roshdy;Metwally, Khaled Abdel-Aziz;Ahmed, Marwa M. Samir S.
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권3호
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    • pp.1235-1239
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    • 2015
  • Background: Fragile histidine triad (FHIT) gene is a tumor suppressor gene which involved in breast cancer pathogenesis. Epigenetics alterations in FHIT contributes to tumorigenesis of breast cancer. Objective: Our objective was to study FHIT promoter region hypermethylation in Egyptian breast cancer patients and its association with clinicopathological features. Materials and Methods: Methylation-specific polymerase chain reaction was performed to study the hypermethylation of FHIT promoter region in 20 benign breast tissues and 30 breast cancer tissues. Results: The frequency of hypermethylation of FHIT promoter region was significantly increased in breast cancer patients compared to bengin breast disease patients. The Odd's ratio (95%CI) of development of breast cancer in individuals with FHIT promoter hypermethylation (MM) was 11.0 (1.22-250.8). There were also significant associations between FHIT promoter hypermethylation and estrogen, progesterone receptors negativity, tumor stage and nodal involvment in breast cancer pateints. Conclusions: Our results support an association between FHIT promotor hypermethylation and development of breast cancer in Egyptian breast cancer patients. FHIT promoter hypermethylation is associated with some poor prognostic features of breast cancer.

자계 결합 무선 전력 전송에서의 결합 계수 추출 방법 (Extraction Solution for the Coupling Coefficient at the Magnetically Coupled Wireless Power Transmission)

  • 김건영;이범선
    • 한국전자파학회논문지
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    • 제23권9호
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    • pp.1073-1078
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    • 2012
  • 본 논문에서는 손실을 고려한 등가 회로 분석을 통하여 자계 결합 무선 전력 전송 시스템에서의 결합 계수 추출식을 유도하였다. 부하 저항을 고려한 유도된 추출식을 이용하여 결합 모드 이론을 이용한 기존의 추출식을 일반화시켰다. 따라서 우수/기수 모드 해석이 불필요하기 때문에 측정 과정에서 쉽게 결합 계수를 구할 수 있다. 또한, EM 시뮬레이션에서 두 루프를 통과하는 자속의 비를 이용하여 구한 결합 계수와 유도된 추출식을 이용하여 구한 결합 계수가 일치함을 확인할 수 있다. 자계 결합 무선 전력 전송에서의 정확한 결합 계수를 추출한다면, 시스템을 분석하고 최적화시키는 데 유용하게 활용할 수 있다.

렙틴 수용체 유전자 다형성에 따른 대학생의 생화학 지표와 체지방 분포에 관한 연구 (Study on Biochemical Parameters and Body Fat Mass according to Leptin Receptor Polymorphism in University Students)

  • 김경희;조희숙
    • 동아시아식생활학회지
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    • 제22권2호
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    • pp.219-223
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    • 2012
  • The purpose of this study was to investigate the body composition, biochemical parameters, and consumption of convenience foods according to leptin receptor polymorphism in university students. A survey was conducted on a total of 418 students - 271 males and 147 females. Based on a self-reporting method, questionnaires were administered for over 20 minutes, and leptin receptor and blood samples were analyzed. The genotype frequencies of leptin receptor polymorphism were Gln/Arg heterozygote (64.8%) and Gln/Gln homozygote (35.2%). Leptin polymormphism showed no significant association with biochemical parameters(ALT, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, and hemoglobin) and body composition. GG homozygote was associated with a higher risk of visceral fat obesity compared to those with GA heterozygote (odd ratio 1.758, 95% confidence intervals 0.812~3.803). Leptin polymorphism appeared to be a genetic risk factor for visceral fat obesity. This study suggests that leptin polymorphism has a causative role to body fat distribution in Korean.

감정노동 수행시간과 근육통의 관련성 (The Relationship between Emotional Working Hour and Muscle Pain)

  • 이복임
    • 한국직업건강간호학회지
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    • 제23권4호
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    • pp.269-276
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    • 2014
  • Purpose: The purpose of this study was to investigate muscle pains of emotional laborers and determine whether there were differences in their muscle pains depending on the hours spent on emotional labor. Methods: This is a secondary analysis of the data collected from the 3rd (2011) Korean Working Conditions Survey. 50,032 participants responded to the study's questionnaire. Among them, 15,669 participants were emotional laborers who directly dealt with people such as customers, passengers, pupils, patients, etc. Results: Thirty three percent of subjects had reported muscle pains. Muscle pains of subjects were positively related to the hours spent on emotional labor (p<.001). According to the logistic regression analysis, the adjusted odd ratio of the subjects who spent about almost all of the work hours on emotional labor was 1.32 (95% CI: 1.15~1.52), compared to the subjects who spent about a quarter of their work hours on emotional labor, when other factors were controlled. Conclusion: The study's findings indicate that engaging in emotional labor for longer hours increases the risks of muscle pains. Occupational nurses must pay closer attention to the management of muscle pains of emotional laborers.

한국 청년의 치주건강에 대한 건강행태의 영향- 제6기 국민건강영양조사 (Effects of health behaviors on the periodontal health status of Korea young man: The 6th Korean National Health and Nutrition Examination Survey)

  • 한수진
    • 한국치위생학회지
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    • 제18권6호
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    • pp.957-967
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    • 2018
  • Objectives: The aim of this study was to confirm health behaviors that affect periodontal health status. Based on these results, we also intended to provide information for the prevention of gingivitis prior to periodontitis and establish strategies for maintaining healthy periodontal tissues. Methods: Data for this descriptive study were extracted from the Korea National Health and Nutrition Examination Survey 2013-2015. A total of 2,710 adults, aged 19-39 years were included in this study. Complex logistic regression analyses were performed to confirm relationships between health behaviors and periodontal health, after adjusting for socio-demographics, oral and systemic health status. Results: Dental clinic visits (odd ratio [OR] = 1.761, 95% confidence interval [CI]; 1.391-2.229), use of floss (OR = 1.504, 95% CI; 1.213-1.865), and non-smoking (OR = 1.269, 95% CI; 1.040-1.549) were found to support periodontal health. Conclusions: Dental visits for continued professional oral health care, self-oral care including interdental flossing, and a non-smoking habit, are necessary for periodontal health maintenance. Additionally, the results suggest that physical activities such as regular walking can help. These methods should be considered as the primary preventative care strategies for minimizing the occurrence of gingival inflammation.

Use of N-alkanes to Estimate Intake and Digestibility by Beef Steers

  • Premaratne, S.;Fontenot, J.P.;Shanklin, R.K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제18권11호
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    • pp.1564-1568
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    • 2005
  • The objective of the study was to evaluate the use of n-alkanes to estimate DM intake and digestibility by beef cattle. Six steers were blocked (3 blocks, 2 animals/block) according to the body weight (279${\pm}$19 kg) and randomly allotted within blocks to two diets (3 steers/diet). A second trial was conducted with the same animals (321${\pm}$18 kg) after 36 days (d), using a switch back design. The diets consisted of two types of chopped sun-cured hay, alfalfa (Medicago sativa L) hay, or fescue (Festuca arundinacea Schreb) and alfalfa mixture, which were fed in equal amounts to steers. Animals were dosed with $C_{32}$ and $C_{36}$ alkanes, employing an intra-ruminal controlled-release device at the beginning of each trial. Hay intake per animal was measured from d 6 to 12 and sub samples were taken for chemical analysis. Rectal samples of feces were taken from each animal once/daily from d 8 to 14, freeze dried, and ground prior to alkane analysis. Alkanes were extracted from ground hay and feces. Feed intake was calculated from the dose rate of $C_{32}$ alkane and, the herbage and fecal concentrations of adjacent odd ($C_{33}$ or $C_{31}$) and even ($C_{32}$) chain length alkanes. Crude Protein, NDF, ADF, ash concentrations and In vitro dry matter digestibility (IVDMD) were 17.7, 42.2, 28.4, 7.9 and 71.7 for alfalfa, and 12.4, 56.5, 30.4, 6.9 and 69.1% for fescue/alfalfa mixture, respectively. For both diets, intake estimated from $C_{33}$:$C_{32}$ ratio was not different from the measured intake, but intake estimated from $C_{31}$:$C_{32}$ ratio was lower (p<0.05), than the measured intake for both diets. The average estimated forage intake from $C_{33}$:$C_{32}$ ratio was 4.86 and 0.69% below than the measured intake for alfalfa and, fescue/alfalfa mixed diets, respectively. The respective estimates with $C_{31}$:$C_{32}$ ratio were 9.59 and 11.33% below than the measured intake. According to these results, alkane $C_{33}$:$C_{32}$ ratio is better than alkane $C_{31}$:$C_{32}$ ratio for the estimation of intake by beef steers.

개선된 전력 분배율을 갖는 태극형 방향성 결합기에 관한 연구 (A Study on the Taegeuk Shaped Directional Coupler with Improved Power Split Ratio)

  • 양규식;오양현;이종악
    • 한국전자파학회지:전자파기술
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    • 제2권2호
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    • pp.19-24
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    • 1991
  • 본 논문에서는 태극 모양의 새로운 방향성 결합기를 고안하여 높은 전력 분배율을 실현할 수 있음을 실험을 통하여 입증하였다. 제안돈 태극형 방향성 결합기는 하이브리드 링형 방향성 결합기의 $3\lambda/4$부분을 적극적으로 활용하기 위하여 태극 모양의 구조를 취했으며, 우수 기수 모드 해석법을 이용하여 완전정합과 분리 조건을 만족하는 각 지로의 어드미턴스를 구하였다. 그 결과 마이크로 스트립 라인으로 제작 가능한 저항의 범의 내에서 이미 발표된 연구 결과에서와 같은 크기의 회로 면적내에서도 훨씬 높은 전력 분배율(최대 28DB)을 실현할 수 잇음을 알았으며, CGP-502기판을 이용하영 중심 주파수 10GHz에서 0,8,16dB 전력 분배율을 갖는 태극형 방향성 결합기를 설계 제작하고 실험을 하여 이론의 타당성을 확인하였다.

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동축선을 이용한 광대역 전력 분배기 (Wideband Power Divider Using a Coaxial Cable)

  • 박웅희
    • 한국정보통신학회논문지
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    • 제16권4호
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    • pp.661-668
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    • 2012
  • 높은 전력과 광대역에서 동작하는 동축선을 이용한 임피던스 트랜스포머는 추가적인 동축선을 이용하면 다양한 임피던스 변환 비율을 가질 수 있다. 50-${\Omega}$ to 25-${\Omega}$의 임피던스 변환 비율의 동축선 임피던스 트랜스포머에 50-${\Omega}$ 선로 두 개를 25-${\Omega}$ 지점에 병렬 연결하면 쉽게 광대역에서 동작하는 전력 분배기를 제작할 수 있다. 이런 동축선을 이용한 광대역 전력 분배기는 두 개의 출력 단자의 단자 정합 특성과 출력 단자사이의 격리 특성이 매우 낮아 개선이 필요하다. 본 논문에서는 단일 종단 여파기 설계 방식을 이용하여 동축선을 사용한 전력 분배기의 단자 정합 특성과 격리 특성을 개선하였다. 먼저, 저주파 대역 통과 단일 종단 여파기 계수를 이용하여 ADS 시뮬레이션을 통해 2-way 전력 분배기의 정합 단자 수와 Ripple에 따른 동작 특성을 살펴보았고, 종단 정합이 없는 전력 분배기와 2단 정합과 4단 정합을 가지는 전력 분배기를 제작하여 출력 단자의 정합 특성 및 격리 특성의 개선 정도를 살펴보았다.

큰검정풍뎅이와 참검정풍뎅이 성충의 비상활동 (Flight Activities of Larger Black Chafer (Holotrichia morosa Waterhouse) and Korean Black Chafer (H. diomphalia Bates))

  • 김기황
    • 한국응용곤충학회지
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    • 제29권4호
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    • pp.222-229
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    • 1990
  • 1984-1989년의 6년간 Blacklight trap에 유살된 성충수를 통하여 큰검정풍댐이와 참검정풍뎅이와 참검정풍뎅이 성충의 비상활동을 조사하였다. 큰검정풍뎅이 성충의 비상 활동은 주로 6월 하순-8월 상순에 이루어지고 7월 중순에 peak으며, 참검정풍뎅이 성충의 비상 활동은 주로 홀수년도의 5 월 상순-6월 하순에 이루어졌는데 peak의 시기는 해에 따라 일정치 않았다. 두 종의 비상 기간 중의 비상 활동은 모두 강우량이 많은 시기에 활발하였으며 참검정풍뎅이 월동 성충의 비상 활동은 일평균기온 $15^{\circ}C$ 이상 되면서 시작되는 것으로 보였다. Blacklight trap에 유살된 성충의 성비에 있어, 큰검정풍뎅이는 자충이 53.3%였으나 참검정풍뎅이는 야외 채집 성충의 57.4%가 자충이 었음에도 불구하고 자충이 전혀 없었다.

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성별에 따른 알코올사용행태와 대사증후군과의 관계 - 제5기 2010년 국민건강영양조사 자료를 이용하여 - (Gender Differences in the Relationship between Alcohol Use Behaviors and Metabolic Syndrome - Korean National Health and Nutrition Examination Survey (KNHANES) V 2010 -)

  • 류지영;김대환
    • 보건교육건강증진학회지
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    • 제30권1호
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    • pp.83-93
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    • 2013
  • Objectives: The objective of this study was to assess the gender differences in the relationship between alcohol use behaviors and the risk of metabolic syndrome among Korean adult population. Methods: Data from the Korean National Health and Nutrition Examination Survey (5th, 2010) was analyzed. Using the Alcohol Use Disorders Identification Test, subjects were classified into 4 groups including non-drinking, low-risk drinking, medium-level alcohol problem, and high-level alcohol problem group. Metabolic syndrome and its components were compared among the alcohol behavior groups by gender. Results: The odds ratio vs. non-drinking group for metabolic syndrome was significantly higher in male medium and high-level alcohol problem group. In female, high-level alcohol problem group showed significantly higher odds ratio for metabolic syndrome. Blood pressure and HDL-cholesterol were likely to be higher with the excessive drinking behaviors in both men and woman. Triglyceride level in men was significantly higher in the medium and high-level alcohol problem group than non-drinking group. Although fasting glucose level did not show differences among drinking groups, the odd ratios vs. non-drinking group for the hyperglycemia (${\geq}$ 100mg/dl) were significantly higher in female drinking groups. Conclusions: Problematic alcohol drinking is likely to increase the risk of metabolic syndrome in Korean adults.