The present study was conducted to propose future research directions for weed management by examining the current trends of research on weed occurrence according to cropping systems. The cropping systems are developed for the efficient use of arable land, and the weed flora changes according to the management practices of a given cropping system. In particular, weed occurrence can be reduced by altering the soil environment. In addition, cultivation methods, such as tillage, affect the weed seed bank in the soil, thus altering the pattern of weed occurrence. Here, we propose three weed management practices according to the cropping system. First, it is necessary to develop a model that can classify weed species by analyzing young seedlings and can predict the flora in the field. Second, it is important to manage the cropping system history and establish a database of agricultural information, which can be linked to meteorological and geographic data. Third, it is critical to estimate the weed occurrence and soil seed bank dynamics, based on which a cropping system platform and digitalization technology can be developed. In the future, the prediction of weed occurrence and control according to the cropping system will contribute to sustainable agriculture by reducing the use of herbicides and solving the problems of resistant weeds.
Purpose: The purpose of this study was to describe sports injuries among elderly people and to compare physical activity, perceived health status and exercise self-efficacy between elderly people who had experienced a sports injury and elderly people who hadn't. Methods: The sample of this study were 100 elderly in Korea, 51 of whom had had a sports injury. The study used questionnaires to gather data. There were 8 demographic factors, 4 factors related to physical activity, perceived health status and exercise self-efficacy of the subjects. Data were analyzed by frequencies, chi-square test, and t-test. Result: Among the sports injured elders, one occurrence of a sport injury was 86.3%. There were more outdoor than indoor sports injuries of elders (66.7%), and sports injuries of elders occurred more in the winter (82.7%). The major cause of the sports injuries was loss of balance. Ankles were frequently damaged from these injuries. The most significant change after the sports injury was reduction of physical activity (60.8%). There were significant differences between sports injured elderly and non-injured elderly for age (${\chi}^2=2.58$, p=.011) and the amount of physical activity (t=1.96, p=.050), but there was no significant difference in perceived health status and exercise self-efficacy. Conclusion: To prevent sports injuries in the elderly means to maintain a medium level of physical activity and to improve their balance.
Background: The activation and inactivation of receptor tyrosine kinases are tightly regulated to ensure faithful replication of cells. After having transduced extracellular growth activating signals, activated EGFR is subjected to downregulation either by clathrin mediated endocytosis or c-Cbl mediated proteasome degradation depending on the ligand concentration. c-Cbl is an ubiquitin ligase which requires a phosphorylated tyrosine residue at position 1045 in the cytoplasmic domain of EGFR to interact and add ubiquitin molecules. While activating mutations in exons 19 and 21 have been associated with the development of several cancers, the status of mutations at tyrosine 1045 coding exon 27 of EGFR remain to be investigated. Consistently, defective phosphorylation at 1045 has been associated with sustained phosphorylation of EGFR in non-small lung carcinomas. Hence in the present study we investigated the genetic status of the tyrosine 1045 coding site within exon 27 of EGFR gene to explore for possible occurrence of mutations in this region, especially since no studies have addressed this issue so far. Materials and Methods: Tumor chromosomal DNA isolated from thirty five surgically excised oral squamous cell carcinoma tissues was subjected to PCR amplification with intronic primers flanking the tyrosine 1045 coding exon 27 of EGFR gene. The PCR amplicons were subsequently subjected to direct sequencing to elucidate the mutation status. Results: Sequence analysis identified no mutations in the tyrosine 1045 codon of EGFR in any of the thirty five samples that were analyzed. Conclusions: The lack of identification of mutation in the tyrosine 1045 codon of EGFR suggests that mutations in this region may be relatively rare in oral squamous cell carcinomas. To the best of our knowledge, this study is the first to have explored the genetic status of exon 27 of EGFR in oral squamous cell carcinoma tissue samples.
Ibrahim, Noha Y.;Sroor, Mahmoud Y.;Darwish, Dalia O.
Asian Pacific Journal of Cancer Prevention
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v.16
no.3
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pp.1007-1010
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2015
Background: The clinical significance of bilateral breast cancer is unclear and its influence on prognosis is controversial. Materials and Methods: Between 2005 and 2009 we identified 110 cases of bilateral breast cancer (BBC) ; 49 patients had synchronous (duration between the occurrence of carcinoma in both breasts was less than 12 months) and 61 had metachronous (duration was more than one year with no ipsilateral local recurrence). We compared the patient characteristics including age, menopausal status, clinical stage, tumor size, histological classification, lymph node status, and hormone receptor and Her-2 status. We also compared the treatment given and overall and disease free survival (DFS) of both groups. Results: Synchronous cases tend to present more aggressively than metachronous cases and age at first presentation adversely affects survival. The 5 year overall survival was 78.7% for metachronous and 60% for synchronous. Patients with positive hormonal status had better five year disease free survival in metachronous compared to synchronous cases, at 76% and 63%, respectively. Age at first presentation >45years had better DFS (65%) compared to those with age ${\leq}45$ years (52%) at 5 years follow up. Conclusions: Patients with synchronous breast cancer may have worse prognosis. Young age and hormone receptor negative were risk factors in our study. Close follow up and early detection of contralateral breast cancer is mandatory.
Purpose: Chemotherapy-induced nausea and vomiting (CINV) can cause severe malnutrition. However, relationships between CINV levels, non-pharmacological coping methods, and nutritional status of female cancer patients have rarely been investigated. Therefore, this study aimed to analyze their relationships in gynecologic cancer patients. Methods: Participants receiving a highly and moderately emetogenic chemotherapy were recruited. The level of CINV was assessed using a numeric rating scale. Coping methods were determined using multiple-choice self-report questionnaires and categorized into seven types for statistical analysis. Nutritional status was evaluated using biochemical and anthropometric parameters. Results: Among all the 485 patients, 200 eligible inpatients were included. Despite the administration of prophylactic antiemetics, 157 patients (78.5%) still experienced CINV, and several used nonmedically recommended coping methods, such as just enduring the symptom or rejecting food intake. A total of 181 patients (90.5%) had nutritional disorders. Although the level of CINV was indirectly related to the occurrence of nutritional disorders, patients who rejected food (${\beta}=1.57$, p=.023) and did not use physical measures (${\beta}=-1.23$, p=.041) as coping methods were under the high risk of nutritional disorders. Conclusion: Korean gynecologic cancer patients had high levels of CINV and were at high risk of nutritional disorders, which may be related to the use of nonscientific coping methods, possibly due to cultural backgrounds and lack of proper nutritional program. Therefore, developing a culturally appropriate educational program for the cancer patients with CINV is urgently needed.
Lee, Seon Hye;Lee, Haejung;Hyun, Sookyung;Lee, Mi Soon;Kim, Do Hyung;Kim, Yeong Dae
Journal of Korean Biological Nursing Science
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v.23
no.1
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pp.11-21
/
2021
Purpose: The aim of this study was to examine the nutritional intake status of the lung cancer patients who underwent pulmonary resection and to analyze the relationship between the status of the nutritional intake and the occurrence of postoperative pulmonary complications. Methods: This study was a secondary analysis to determine whether the changes in the nutritional intake after surgery were related to pulmonary complications. Data of a total of 89 patients were included in the analysis and the nutritional intake status was confirmed using a 24-hour dietary recall method. The data were analyzed by descriptive statistics, chi-square or Fisher's exact test, and ANOVA using the SPSS WIN 26.0 program and word clouds were generated using the R software program. Results: Overall, a decrease in the postoperative nutritional intake was observed in the patients who underwent pulmonary resection, except for the intake of fat. The pulmonary complications were identified to be associated with BMI and the presence of comorbidity. Twenty-three out of 74 patients with vitamin E levels below the Estimated Average Requirements developed pulmonary complications after surgery. Conclusion: Lung cancer patients who underwent pulmonary resection generally have difficulty in acquiring appropriate nutritional intake and need balanced nutritional management. Future investigations on the impact of increased vitamin E intake on postoperative pulmonary complications may provide better insight into the relationship between vitamin E intake and pulmonary complication among patients who underwent pulmonary resection.
Journal of the Korea Academia-Industrial cooperation Society
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v.22
no.2
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pp.459-467
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2021
This study examined the onset of adolescent delinquency through discrete-time survival analysis. Our analysis used data obtained from the Korean Children & Youth Panel Survey, and included 2,277 middle school students. The main analysis results are as follows. First, the hazard probability for the occurrence of delinquency was the highest at 16.6% in the second year of middle school, slightly decreased in the third year of middle school, but continued to increase as the overall grade increased. Second, adolescent psychological and emotional factors have significantly affected the onset of delinquency. Third, negative parenting methods had a significant impact on delinquency, but neglect was not significant. Fourth, having delinquent friends was an important factor affecting the status of delinquency. Fifth, among the school factors, adjustment of learning activities, adjustment of school rules, and adjustment of friendship relations influenced the status of delinquency, while the adjustment of teacher relations was not significant. As early intervention is important to prevent juvenile delinquency, education and support for establishing healthy relationships are needed.
Seoul Metro railway facilities' inspection and maintenance tasks cause failure analysis, but if there is trouble the diverse cause investigation and the systematic analysis and management among broken facilities, related facilities and components fell short and the conditions are different. And, excess and insufficiency, under inspection and maintenance, is being raised regardless of the introduction year and the operating environment including the number of use by applying the same facilities in the uniform inspection cycle. In this study, we will analysis systematically facility system information, failures, operational status, performance, fault and maintenance information resulting from the maintenance management of railway facilities and derive the relationship between associated equipment and its components. In addition, optimizing the inspection and the maintenance cycles of railway facilities, we will improve the reliability of operation. Considering the probability of risk, it is possible to predict the occurrence of accidents or faults and to minimize the frequency of breakdown by pre-inspection maintenance. Finally, This paper is to introduce the content of constructing the Seoul Metro RCM-based failure analysis system for railway facilities to support the optimal continuance of operation status of equipments and the securement of the safe operation of vehicles.
This study examines married couples' forgiveness and forgiveness process in order to provide basic information related to married couples' forgiveness and to identify significant variables through analyzing socio-demographic characteristics affecting forgiveness and what influences the forgiveness process variables. Based on the study, the conclusions are as follows: First, men are affected by personal and intrinsic factors and women are affected by the other person's factor in the forgiveness. Married couples all expect that self-growth and the recovery of negative emotion occur through forgiveness. It indicates that the forgiveness contains a strong selfish character and not an altruistic character for others. Second, married couples experience hurt in the martial relationship due to problems caused by relationships with the husband's family, wife's family, and relatives. There is a significant difference between men and women in the period of problem occurrence, period of worry, seriousness degree of the problem, intention status of the problem, hurt degree, unfairness status of hurt, unfairness degree of hurt, and locus of control. Third, men's forgiveness level is higher in emotional forgiveness, cognitive forgiveness, and behavioral forgiveness. Among them, there is the biggest difference of cognitive forgiveness between men and women. Also, the variable affecting forgiveness is different between men and women.
Journal of the Korean Society of Food Science and Nutrition
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v.27
no.6
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pp.1197-1203
/
1998
This study was conducted to investigate serum lipids and antioxidant vitamins status of male patients with cerebrovascular disease. The study consisted of 16 hospital patients(57.8$\pm$13.7 years) at 3 General Hospitals in Taegu who suffer from cerebrovascular disease and 21 healthy adults(55.5$\pm$7.2 years). The results were as follows: The systolic blood pressure of the patients(150.0$\pm$13.7mmHg) was sig nificantly higher than healthy control(126.0$\pm$17.4mmHg). In patients the percentages of drinking alcohol(more than 5 times/week) and smoking were also higher. And the patients had more stress than control. Total calorie, protein, carbohydrate, vitamin B1 and niacin intakes were significantly lower in the patients. The energy nutrients consumption reached the recommended level in all subjects who were investigated. HDL cholesterol(24.99 vs 37.86mg/dl) and vitamin E(12.94 vs 20.88mg/L) level showed significantly lower, but triglyceride level(175.50 vs 117.69mg/dl), total cholesterol/HDL cho lesterol(6.22 vs 4.39) and atherogenic index(5.22 vs 3.39) were significantly higher in the patient group. Therefore, it might be expected that refraining from drinking alcohol and smoking, and that having proper exercise and certain other healthy living habits which can decrease stress in addition suitable consumption of antioxidant vitamins can prevent the occurrence of cerebrovascular disease.
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