• 한국콘텐츠학회논문지
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• 제15권10호
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• pp.626-635
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• 2015

건강에 대한 사회적인 욕구와 관심에 따라 만성질환 예방 및 식생활관리 서비스의 새로운 모델로 U-Healthcare 서비스가 주목 받고 있다. 본 연구는 50세 이상의 남녀 중장년층을 대상으로 U-Healthcare 서비스 관련 요구 특성을 조사하였다. 조사대상의 U-Healthcare 서비스에 기대하는 부분으로 개인 맞춤형 진료 및 관리 부분(37.7%), 개인의 건강상태의 체계적인 파악(21.4%)이 높게 나타났다. 건강관리 이용 분야에서는 식이요법 관리(43.9%)가 가장 높게 나타나 U-Healthcare 서비스에서 개인 맞춤형 식이요법 서비스가 필요할 것으로 보였다. 건강 정보 검색 관심분야는 질병관리(35.6%), 식재료(28.6%), 건강음식 조리법(22.7%) 순으로 나타나 조사대상의 50% 이상이 식품에 관심이 있었다. 식단 정보에 대한 요구사항은 영양성분, 건강상태별(질환별) 맞춤형 식단 등을 5점 척도로 조사한 결과 모든 항목이 3.9 이상의 필요성이 있다고 답변하였다. 이상의 결과를 통해 현재의 중장년층은 U-Healthcare 서비스를 통해 질병관리와 더불어 식생활 관리 서비스를 요구하고 있는 것을 확인하였다. 따라서 본 연구의 후속 연구로 남녀 중장년층 집단의 요구 특성을 반영하여 원격 진료를 통해 매일매일 개인의 건강상태 및 질환의 진행 정도를 파악하고 그에 따라 필요한 식재료, 식단, 조리법에 대한 처방을 U-Healthcare 서비스로 제공할 수 있는 데이터베이스를 구축하고자 한다. 이를 통해 식생활 관리 콘텐츠의 활용도를 높이고 미래의 고령자들이 건강한 삶을 영위할 수 있을 것으로 기대한다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권6호
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• pp.521-530
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• 2020

Purpose: Malnutrition is a common feature in critically ill children. Enteral nutrition (EN) is the main strategy to nutritionally support critical ill children, but its use can be hindered by the development of intolerance. The study aimed to assess the effectiveness and safety of amoxicillin/clavulanate (A/C) to treat EN intolerance. Methods: We retrospectively evaluated patients admitted to the pediatric intensive care unit from October 2018 to October 2019. We conducted a case-control study: in the first 6 months (October 2018-April 2019) we implemented the nutritional protocol of our Institution with no drug, whereas in the second half (May 2019-October 2019) we employed A/C for 1 week at a dose of 10 mg/kg twice daily. Results: Twelve cases were compared with 12 controls. At the final evaluation, enteral intake was significantly higher than that at baseline in the cases (from 2.1±3.7 to 66.1±27.4% of requirement, p=0.0001 by Wilcoxon matched-pairs signed rank test) but not in the controls (from 0.2±0.8 to 6.0±14.1% of the requirement, p=NS). Final gastric residual volume at the end of the observation was significantly lower in the cases than in the controls (p=0.0398). The drug was well tolerated as shown by the similar safety outcomes in both cases and controls. Conclusion: Malnutrition exposes critically ill children to several complications that affect the severity of disease course, length of stay, and mortality; all may be prevented by early EN. The development of intolerance to EN could be addressed with the use of A/C. Future prospective clinical trials are needed to confirm these conclusions.

• Journal of Nutrition and Health
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• 제54권6호
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• pp.584-593
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• 2021

2020 한국인 영양소 섭취기준에서 탄수화물은 만성질환 예방을 위한 섭취기준으로 총 에너지 섭취량에 대한 탄수화물로부터의 에너지 섭취비율인 에너지적정비율을 1세 이후 모든 연령에서 55-65%로설정하였다. 그리고 2020년에 처음으로 탄수화물의 평균필요량과 권장섭취량을 설정하였다. 인체의 탄수화물 필요량은 뇌에서 하루에 소비되는 포도당량과 케톤체 생성이 나타나지 않는 양을 기준으로 1세 이후 모든 연령에서 1일 100 g을 설정하고, 권장섭취량은 15% 변이계수를 사용하여 두 배의 변이계수를 더한 130 g/일로 설정하였다. 탄수화물의 평균필요량은 최소필요량의 개념이지 에너지원으로서 적절한 섭취량에 대한 개념은 아니므로 탄수화물의 영양소섭취상태를 평가할 경우에는 평균필요량이나 권장섭취량에 비교하는 것은 적절하지 않고, 에너지적정비율을 활용하여 탄수화물로부터의 에너지 섭취비율의 적절성을 평가하는 것이 적절하다. 탄수화물은 에너지 적정비율범위에서 섭취할 때 만성질환의 위험을 낮출 수 있으며, 이를 탄수화물의 양뿐만 아니라 급원도 고려하는 식생활에 활용해야 할 것이다.

• Journal of Nutrition and Health
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• 제55권1호
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• pp.10-20
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• 2022

2020 한국인 영양소 섭취기준 개정에서 단백질은 기본적으로 질소평형을 유지하는데 필요한 단백질 양 0.66 g/kg 체중/일에 이용효율 90%를 적용한 평균필요량 0.73 g/kg 체중/일과 변이계수 12.5%를 적용한 권장섭취량 0.91 g/kg 체중/일을 생애주기별 체위기준치 변화에 따라 제시하였다. 그러나 성장기의 단백질 섭취기준에서는 체중 기준을 2017년에 개정된 소아청소년 성장도표에 근거하고, 일본 DRI 자료를 참고로 단백질 식품 이용효율을 차등 적용하였으며, WHO/FAO/UNU 보고서상의 성장에 필요한 단백질량 오류를 수정·반영하여 기준값을 개정하였다. 그 결과 일부 연령구간에서 섭취기준의 상향조정이 있었으나 한국인의 연령대별 1일 평균 단백질 섭취량은 대부분의 연령대에서 단백질 평균필요량의 100%를 넘는 것으로 나타났고, 남자 75세 이상과 여자 65세 이상을 제외하고는 권장섭취량과 비교했을 때도 많은 것으로 나타나 단백질 섭취기준의 상향 조정은 국민의 평균 단백질 섭취기준을 반영하는 것으로 판단된다. 한편, 75세 이상의 단백질 섭취량은 근감소증 예방, 근력 강화 등을 위해 65-74세 단백질 섭취기준과 동일하게 설정하였다. 이번 개정에서 단백질 에너지 적정비율은 기존의 7-20%를 유지하였으나 향후 단백질의 적정한 섭취수준 및 만성질환예방을 위한 단백질 필요량 설정에 관한 과학적 근거마련을 위해 우리나라 국민을 대상으로 한 다양한 중재연구가 수행되어야 할 것이다.

• 미생물학회지
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• 제28권1호
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• pp.47-54
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• 1990

섬유소를 분해할 수 있는 Cellutomonas flavigena NCIB 12901 과 Cellulomonas bibula NCIB 8142의 종간 원형질체 융합을 하고 그로부터 얻은 융합체의 특성을 조사하였다. C. bibuta의 원형질체는 lysozyme(600Ieιllulomoηas libula NCIB 8142의 종간 원형 섣처l 융 한응 하고:1로부터 얻은융합셰익 특성을 조사하였다 . C bibula의 원형선셰는 lysozyme $600{\mu}{\textrm{g}}$/ml)를 6시간 처리하여 얻었으며, 삼투안정제로는 O.5M sorbitol의 최저이었고 원형질체 재생률은 6.7%였다. 원형질체 융합은 25mM $CaCl_{2}$를 포함하는 40% PEG (M.W.6000)를 $30^{\circ}C$에서 30분간 처리함으로 수행하였고 C. bibuιl와 C. flavigeηa의 융합 빈도는 $5\times 10^{-4}$으로 원형질체 형성 및 합체를 얻었고, 모균주와 융합체의 영양요구성, 항생물질 내성, 효소활성, 세포벽 성분, 운동성 등을 비교하여 융합체는 모균주의 재조합체임을 밝히었다.

• Asian-Australasian Journal of Animal Sciences
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• 제23권7호
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• pp.916-923
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• 2010

We report nutritional physiology and non-specific immune responses of vitamin E in parrot fish for the first time. This study aimed to investigate the essentiality and requirements in diets based on growth performances, non-specific immune responses and a challenge test against Vibrio angullarum. Six casein-gelatin based semi-purified diets were formulated to contain six graded levels of DL-${\alpha}$-tocopheryl acetate (${\alpha}$-TA) at 0, 25, 50, 75, 100 and 500 mg/kg diet (designated as E0, E25, E50, E75, E100 and E500, respectively) and fed to triplicate groups of juvenile parrot fish for 12 weeks. The analyzed dietary concentrations of vitamin E were 0, 38, 53, 87, 119 and 538 mg/kg diet for E0, E25, E50, E75, E100 and E500, respectively. At the end of the feeding trial, growth performance and feed utilization of fish fed the E25 were significantly higher compared to that of fish fed the other diets. Liver ${\alpha}$-tocopherol concentration was significantly increased with an increase in dietary ${\alpha}$-TA in a dose dependent manner. No apparent clinical signs of vitamin E deficiency and mortality were observed in fish fed the basal diet for 12 weeks. Among the immune responses assayed, phagocytic (NBT assay) and myeloperoxidase activities were significantly increased with increment of dietary ${\alpha}$-TA levels. During the challenge test with V. anguillarum, E75, E100, and E500 diets resulted in higher survivals than E0, E25 and E50 diets. The findings of this study suggest that parrot fish require exogenous vitamin E and the optimum dietary level could be approximately 38 mg ${\alpha}$-TA/kg diet for normal growth and physiology. Dietary ${\alpha}$-TA concentration over 500 mg/kg could be required to enhance the nonspecific immune responses and improve the resistance of juvenile parrot fish against V. anguillarum.

• Nutrition Research and Practice
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• 제7권3호
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• pp.216-223
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• 2013

The purpose of this study is to assess folate intake, and serum and red blood cell (RBC) folate concentrations, and investigate the association between folate status and health-related behaviors among Korean college students. A total of 169 students, aged between 18 and 27 years, participated in this study. Dietary intake data were collected by trained interviewers using a 24-hour recall method for three non-consecutive days in 2009. Information on health-related behaviors was obtained by a self-administered questionnaire. Serum and RBC folate concentrations were measured by microbiological assay. The average intakes of folate were $456{\mu}gDFE$ and $347{\mu}gDFE$ in male and female students, respectively. While the average serum folate concentration was significantly lower in male students (8.9 ng/mL) compared to female students (12.5 ng/mL), RBC concentrations were not significantly different between male (398.6 ng/mL) and female students (405.3 ng/mL). In male students, low serum folate concentrations were associated with total folate intake less than the Estimated Average Requirement, non-use of folic acid supplements, smoking, alcohol drinking at least once a week and low physical activity. In female students, low serum folate concentrations were associated with smoking and alcohol drinking at least two drinks at a time and BMI ${\geq}25$. Alcohol drinking and low physical activity were also associated with low RBC folate concentrations in both male and female students. In order to improve folate nutritional status of college students, the practice of desirable health-related behaviors, such as non-smoking, moderate alcohol drinking, regular physical activity, and maintenance of healthy BMI should be encouraged along with consumption of folate-rich foods and supplements.

• Journal of Nutrition and Health
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• 제43권6호
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• pp.628-637
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• 2010

To determine vitamin A and E intakes and their food sources, dietary intakes were collected by three consecutive 24-hour recalls from 192 adults living in Seoul and Gyeonggi Province, Korea. The mean vitamin A, retinol and ${\beta}$-carotene intakes were $1240.1{\pm}1101.1\;{\mu}g$ retinol equivalent/day ($693.3{\pm}563.2\;{\mu}g$ retinol activity equivalent/day), $182.6{\pm}149.5\;{\mu}g$/day and $5443.3{\pm}6365.5\;{\mu}g$/day, respectively. Only 9.4% of the subjects consumed less than the Korean Estimated Average Requirement for vitamin A. The mean vitamin E intake was $6.03{\pm}2.54\;mg$ ${\alpha}$-tocopherol equivalent/day. The ${\alpha}$-tocopherol and ${\gamma}$-tocopherol intakes were $4.83{\pm}2.03$ and $5.57{\pm}3.41\;mg$/day, respectively. Most of the subjects (93.8%) consumed less than the Korean Adequate Intake for vitamin E. The major food sources of vitamin A were sweet potato, carrot, red pepper powder, spinach, and citrus fruit, and the top 30 foods provided 91.5% of total Plant foods provided 81.0% and animalderived foods 10.5% of the vitamin A intake from the top 30 foods. The major food sources of vitamin E were soybean oil, red pepper powder, Ramyeon (cup noodles), spinach, and egg. The top 30 foods provided 78.0% of total vitamin E intake. Plant foods provided 61.3% and animal-derived foods 15.9% of the vitamin E intake from the top 30 foods. In conclusion, the vitamin A intake of the Korean adults in this study was ge-nerally adequate, but the vitamin E intake of many subjects was inadequate. Therefore, nutritional education may be of benefit to Korean adults to increase their vitamin E intake.

• Nutrition Research and Practice
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• 제12권1호
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• pp.47-51
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• 2018

BACKGROUND/OBJECTTIVES: The purposes of the study were to investigate folate intakes and plasma folate concentrations as well as estimate folate status in Korean healthy adults. SUBJECTS/METHODS: A total of 254 healthy 19- to 64-year-old adults (68 men and 186 women) living in Seoul metropolitan area, Gumi, and Kwangju, Korea participated. Three consecutive 24-hour dietary recalls, information on folate supplementation, and fasting blood samples were collected from the subjects. RESULTS: The mean dietary folate intakes were 587.4 and $499.2{\mu}g$ dietary folate equivalent (DFE)/day for men and women, respectively. The median dietary intakes of men and women were 566.6 and $474.6{\mu}g\;DFE/day$, respectively. Forty subjects (16.7% of total) less total folate than the estimated average requirement (EAR). Folate intakes of 23.3% of men and 34.8% of women aged 19-29 years did not meet the EAR for folate. Major food sources consumed for dietary folate were baechukimchi (Chinese cabbage kimchi), rice, spinach, eggs, and laver, which provided 44% of dietary folate intake for the subjects. Plasma folate concentrations were 23.4 nmol/L for men and 28.3 nmol/L for women, and this level was significantly lower in men than in women. Approximately 13% of men and 3% of women were folate-deficient, and the percentages of subjects showing folate concentrations lower than 10 nmol/L were 27.9% of men and 6.4% of women. CONCLUSIONS: Folate intakes of Korean adults in this study were generally adequate. However, one-third of young adults had inadequate folate intakes.

• Asian-Australasian Journal of Animal Sciences
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• 제5권2호
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• pp.383-388
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• 1992

Nutritional status of macro minerals (Ca, Mg and P) in goats grazed on the native pasture was investigated for 2 years in Luzon Island, Republic of the Philippines. Three regions in Luzon Island (Los Banos; Southern area, Munoz, Nueva Ecija; Central area and Baguio; Northern area) were objected to collect the samples of forages and blood of goats on the pasture. The average values in Ca, Mg and P contents of all the forage samples were 0.29-1.32, 0.13-0.56 and 0.15-0.45% of dry matter, respectively, and these figures almost exceeded the required dietary levels for sheep. There was no obvious changes in mineral content of forages between the seasons of rainy and dry, or among regions. In blood Ca level, more than a half of goats (57.9%) without supplement showed the level below the lower limit, and the low level was not improved even when they fed with some supplemental concentrates. The plasma levels of Mg and P were satisfactory, referring to the lower limit of normal level in goats. It is, therefore, necessary to decide the requirement and to establish a most suitable technique for supplying Ca to grazing goats in Luzon Island.