• Title/Summary/Keyword: Nutrient dynamic

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Association of Dietary Quality with Subjective Health-Related Perception and Chronic Diseases According to Age Segmentation of Korean Elderly (한국 노인의 연령 세분화에 따른 식사의 질과 주관적 건강 관련 인식 및 만성질환의 연관성)

  • Lee, Sojeong;Lee, Seungmin
    • Korean Journal of Community Nutrition
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    • v.26 no.5
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    • pp.363-381
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    • 2021
  • Objectives: This study examined the Korean elderly's dietary intake status, subjective health-related perception and chronic disease prevalence among age groups. Associations of dietary quality with subjective health-related perception and chronic diseases were also examined. Methods: Based on data from the 7th National Health and Nutrition Examination Survey, a total of 3,231 elderly were selected and categorized into 4 age groups of '65 ~ 69', '70 ~ 74', '75 ~ 79' and 'over 80'. Nutrient intakes, proportions of those with insufficient nutrient intakes, Korean Healthy Eating Index (KHEI), some subjective health-related perceptions and prevalence of major chronic diseases were compared according to the age groups. Differences in the subjective health-related perceptions and odds ratios of the chronic diseases according to the quartile levels of KHEI within the same age group were analyzed. Results: With the increase of age, several nutrient intakes (P < 0.001) and KHEI scores significantly decreased (P < 0.01). In women, activity restriction increased (P < 0.05), and EQ-5D score decreased with age (P < 0.001). Prevalence of hypertension (P < 0.0001), hypercholesterolemia (P < 0.05) and anemia (P < 0.01) significantly increased, while hypertriglyceridemia (P < 0.01) significantly decreased only in men. Obesity prevalence decreased, while underweight prevalence increased (P < 0.05). Subjective health status, EQ-5D score and PHQ-9 score significantly improved as KHEI score increased in certain age groups of women (P < 0.05). Odds ratio of hypercholesterolemia significantly increased with the increase of KHEI score in 65 ~ 69-year-old women. However, hypertension and anemia significantly decreased with the increase of KHEI score in 75 ~ 79-year-old women (P < 0.05). Conclusions: The study findings suggest that nutrition management and policy for the Korean elderly need to apply a segmented age standard that can better reflect their dynamic characteristics.

A New Perspective on the Heterogeneity of Cancer Glycolysis

  • Neugent, Michael L.;Goodwin, Justin;Sankaranarayanan, Ishwarya;Yetkin, Celal Emre;Hsieh, Meng-Hsiung;Kim, Jung-whan
    • Biomolecules & Therapeutics
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    • v.26 no.1
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    • pp.10-18
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    • 2018
  • Tumors are dynamic metabolic systems which highly augmented metabolic fluxes and nutrient needs to support cellular proliferation and physiological function. For many years, a central hallmark of tumor metabolism has emphasized a uniformly elevated aerobic glycolysis as a critical feature of tumorigenecity. This led to extensive efforts of targeting glycolysis in human cancers. However, clinical attempts to target glycolysis and glucose metabolism have proven to be challenging. Recent advancements revealing a high degree of metabolic heterogeneity and plasticity embedded among various human cancers may paint a new picture of metabolic targeting for cancer therapies with a renewed interest in glucose metabolism. In this review, we will discuss diverse oncogenic and molecular alterations that drive distinct and heterogeneous glucose metabolism in cancers. We will also discuss a new perspective on how aberrantly altered glycolysis in response to oncogenic signaling is further influenced and remodeled by dynamic metabolic interaction with surrounding tumor-associated stromal cells.

Effects of Dietary Lysine Levels on Apparent Nutrient Digestibility and Serum Amino Acid Absorption Mode in Growing Pigs

  • Zeng, P.L.;Yan, H.C.;Wang, X.Q.;Zhang, C.M.;Zhu, C.;Shu, G.;Jiang, Q.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.7
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    • pp.1003-1011
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    • 2013
  • Two experiments were conducted to determine the effects of different dietary lysine levels on the apparent nutrient digestibility, the serum amino acid (AA) concentration, and the biochemical parameters of the precaval and portal vein blood in growing pigs. In Experiment 1, 15 noncannulated pigs received diets with different lysine densities (0.65%, 0.95%, and 1.25% lysine) for 13 d. A total collection digestion test was performed, and blood samples were collected from the precaval vein at the end of the experiment. In Experiment 2, four cannulated pigs were fed the same diets of Experiment 1. The experiment used a self-control experimental design and was divided into three periods. On d 5 of each period, at 0.5 h before feeding and hourly up to 8 h after feeding, single blood samples were collected from catheters placed in the portal vein. In Experiment 1, some serum AAs (including lysine), serum urinary nitrogen (SUN), and total protein (TP) concentrations were significantly affected by the dietary lysine levels (p<0.05). Moreover, the 0.65% lysine treatment showed a significant lower apparent digestibility of gross energy, dry matter, crude protein, and phosphorus than the other treatments (p<0.05). In Experiment 2, serum lysine, histidine, phenylalanine, threonine, valine, isoleucine (p = 0.0588), triglyceride, and SUN (p = 0.0572) concentrations were significantly affected by the dietary lysine levels (p<0.05). Additionally, almost all of the determined serum AA and total AA concentrations reached their lowest values at 0.5 h before feeding and their highest values at 2 h after feeding (p<0.05). These findings indicate that the greatest absorption of AA occurred at 2 h after feeding and that the dynamic profile of serum AA is affected by the dietary lysine levels. Moreover, when the dietary lysine content was 0.95%, the growing pigs achieved a better nutrient digestibility and serum metabolites levels.

Contribution of Nutrient Flux through the Korea Strait to a Primary Production in the Warm Region of the East Sea (동해 난수역의 일차생산에 대한 대한해협 유입 영양염의 기여)

  • Lee, Tongsup;Rho, Taekeun
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.18 no.2
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    • pp.65-69
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    • 2013
  • In situ measurement of a primary production in East Sea, a marginal sea with a fair accessibility, is nonetheless an arduous task because of dynamic variability. In this study, we estimated the mean value of background (gross) primary production over the warm region of the East Sea based on a biogeochemical hypothesis. We propose an immiscible-shoaling hypothesis for the estimation of primary production, which assumes that primary production in the warm region occurred only by the nutrient supply through the Korea Strait. Annual primary production thus estimated is $209\;gC\;m^{-2}\;y^{-1}$, which is comparable to the satellite-based estimates of net primary production in the region. However, since this hypothesis assumes that primary production is based on only the new nutrients supplied to the system, primary production would increase by 40% if we release the assumption, and assume f = 0.6. This suggests that nutrient influx through the Korea Strait alone is more than enough to support primary production previously reported. Primary production may increase as much as two times if we considered other external perturbations excluded intentionally to estimate the background level of primary production, such as coastal upwelling, submerged ground water discharge, aeolian input, ocean dumping, and mixing by typhoons as well as the contribution of cyanobacteria that has not been quantified in the region. This implies the primary production in the warm region of the East Sea would be comparable to that of the Peru upwelling region with f = 0.6.

Change of Chemical Properties and Nutrient Dynamic in Pore Water of Upland Soil During Flooding (담수에 의한 밭 토양 공극수의 화학적 특성 및 영양분 농도 변화)

  • Kim, Jae-Gon;Chon, Chul-Min;Lee, Jin-Soo
    • Economic and Environmental Geology
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    • v.41 no.3
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    • pp.327-334
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    • 2008
  • Understanding the chemical characteristics of sediments and the nutrient diffusion from sediments to the water body is important in the management of surface water quality. Changes in chemical properties and nutrient concentration of a submerged soil were monitored for 6 months using a microcosm with the thickness of 30cm for upland soil and 15cm of water thickness above the soil. The soil color changed from yellowish red to grey and an oxygenated layer was formed on the soil surface after 5 week flooding. The redox potential and the pH of the pore water in the microcosm decreased during the flooding. The nitrate concentration of the surface water was continuously increased up to $8\;mg\;l^{-1}$ but its phosphate concentration decreased from $2\;mg\;l^{-1}$ to $0.1\;mg\;l^{-1}$ during flooding. However, the concentrations of $NH_4^+$, $PO_4^{3-}$, Fe and Mn in the pore water were increased by the flooding during this period. The increased $NO_3^-$ in the surface water was due to the migration of $NH_4^+$ formed in the soil column and the oxidation to $NO_3^-$ in the surface water. The increased phosphate concentration in the pore water was due to the reductive dissolution of Fe-oxide and Mn-oxide, which scavenged phosphate from the soil solution. The oxygenated layer played a role blocking the migration of phosphate from the pore water to the water body.

Disturbance and Its Role in Forest Ecosystems (삼림생태계에서의 교란과 그 역할)

  • 조도순
    • Journal of Plant Biology
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    • v.33 no.2
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    • pp.147-150
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    • 1990
  • Different species with similar niches can coexist in the same community if disturbances prevent compeptitive exclusion of competitively inferior species. Disturbances which open up gaps are common in all kind of community. Even in virgin forests without any artificial disturbance, there exist a significant proportion of trees of early successional shade-in-tolerant species in addition to the dominant late successional shade-tolerant species. In forest ecosystems, most canopy tree species including shade-tolerant ones require one or more gaps in their life-time to reach the canopy. Because of these frequent disturbances, forests can be considered of dynamic mosaics of patches of different ages and with different species composition which are in certain stages of recovery from disturbances. Disturbances temporarily increase the availability of resources such as light, water and soil nutrient for other in dividuals through the death of one or more canopy trees.

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Performances of Intermittently Aerated and Dynamic Flow Activated Sludge Process (2단간헐폭기 및 유로변경 간헐폭기 활성슬러지 시스템을 이용한 도시하수 처리)

  • 원성연;민경국;이상일
    • Journal of environmental and Sanitary engineering
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    • v.13 no.1
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    • pp.26-31
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    • 1998
  • Removal of nitrogen and phosphate in wastewater is concerned to important for the prevention of eutrophication in receiving water and lake. Conventional activated sludge system designed for organics removal can be retrofitted only by modification of aeration basin to maintain anaerobic and aerobic state. Biological nutrient removal processes(BNR) such as Bardenpho, A$^{2}$/O, UCT, VIP were generally used for the treatment of wastewater. However these BNR processes used in large scale WWTP were not suitable in small scale WWTP(i.e., package type WWTP) due to relatively large fluctuation of flow rate and concentration of pollutants. The purpose of this research was to develop the compact, effective and economical package type WWTP for the removals of carbon and nitrogen in small scale wastewater. Intermittently aerated activated sludge system (IADFAS) were investigated for removal of nitrogen in both domestic wastewater, Bardenpho process was also evaluated. Nitrogen removal of IAAS, IADFAS, Bardenpho were 75, 77 and 67%, respectively.

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Intrinsic and Extrinsic Regulation of Hematopoiesis in Drosophila

  • Koranteng, Ferdinand;Cho, Bumsik;Shim, Jiwon
    • Molecules and Cells
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    • v.45 no.3
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    • pp.101-108
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    • 2022
  • Drosophila melanogaster lymph gland, the primary site of hematopoiesis, contains myeloid-like progenitor cells that differentiate into functional hemocytes in the circulation of pupae and adults. Fly hemocytes are dynamic and plastic, and they play diverse roles in the innate immune response and wound healing. Various hematopoietic regulators in the lymph gland ensure the developmental and functional balance between progenitors and mature blood cells. In addition, systemic factors, such as nutrient availability and sensory inputs, integrate environmental variabilities to synchronize the blood development in the lymph gland with larval growth, physiology, and immunity. This review examines the intrinsic and extrinsic factors determining the progenitor states during hemocyte development in the lymph gland and provides new insights for further studies that may extend the frontier of our collective knowledge on hematopoiesis and innate immunity.

Evaluation of Biological Organic and Nutrient Removal Performance in Intermittent MBR Systems by Computer Simulation (컴퓨터 시뮬레이션을 이용한 간헐폭기 MBR시스템에서의 유기물 및 영양염류 처리 성능 평가)

  • Yoo, Hosik;Rhee, Seung-Whee
    • Journal of the Korea Organic Resources Recycling Association
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    • v.21 no.3
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    • pp.82-92
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    • 2013
  • The Intermittent Aeration MBR systems have the advantage of controlling reaction time by changing aeration period and are one of economic BNR systems since these processes do not require MLSS recirculation that demands capital and operation costs. In this study, two intermittent aeration MBR systems were studied by computer simulation: an intermittent aeration MBR system that had both 1hr/1hr and 4hr/4hr aeration/unaeration periods at intermittent reactor and NEW INTERMITTENT-process that was an energy saving process and certified as a new process by Korean government. Since DO concentration reached only at 0.23mg/L at intermittent reactor when it was aerated, the Intermittent aeration MBR system having 1hr/1hr aeration/unaeration period showed simultaneous nitrification/denitrification and had the highest nitrogen and phosphorus removal efficiencies that were 57% and 55%, respectively. Since this study was based on the constant influent flow and characteristics, more studies are needed to define the operational characteristics of intermittent aeration MBR systems under dynamic influent conditions.

Evaluation of Internal Phosphorus Loading through the Dynamic Monitoring of Dissolved Oxygen in a Shallow Reservoir (수심이 얕은 저수지에서 용존산소 동적 모니터링을 통한 인 내부부하 평가)

  • Park, Hyungseok;Choi, Sunhwa;Chung, Sewoong;Ji, Hyunseo;Oh, Jungkuk;Jun, Hangbae
    • Journal of Environmental Impact Assessment
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    • v.26 no.6
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    • pp.553-562
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    • 2017
  • In these days, agricultural reservoirs are considered as a useful resource for recreational purposes, tour and cultural amenity for vicinity communities as well as irrigation water supply. However, many of the agricultural reservoirs are showing a eutrophic or hyper-eutrophic state and high level of organic contamination. In particular, about 44.7% of the aged agricultural reservoirs that constructed before 1945 exceed the water quality criteria for irrigational water use. In addition to external loading, internal nutrient loading from bottom sediment may play an important role in the nutrient budget of the aged reservoirs. The objectives of this study were to characterize variations of thermal structure of a shallow M reservoir (mean depth 1.7 m) and examine the potential of internal nutrient loading by continuous monitoring of vertical water temperature and dissolved oxygen (DO) concentration profiles in 2015 and 2016. The effect of internal loading on the total loading of the reservoir was evaluated by mass balance analysis. Results showed that a weak thermal stratification and a strong DO stratification were developed in the shallow M Reservoir. And, dynamic temporal variation in DO was observed at the bottom of the reservoir. Persistent hypoxic conditions (DO concentrations less than 2 mg/L) were established for 87 days and 98 days in 2015 and 2016, respectively, during the no-rainy summer periods. The DO concentrations intermittently increased during several events of atmospheric temperature drop and rainfall. According to the mass balance analysis, the amount of internal $PO_4-P$ loading from sediment to the overlying water were 37.9% and 39.7% of total loading during no-rainy season in 2015 and 2016, respectively on August when algae growth is enhanced with increasing water temperature. Consequently, supply of DO to the lower layer of the reservoir could be effective countermeasure to reduce nutrient release under the condition of persistent DO depletion in the bottom of the reservoir.