• 소음진동
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• 제10권3호
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• pp.523-530
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• 2000

In this paper we present an efficient method for finite element vibration analysis of a structure with cyclic symmetry and applied it to calculating the natural vibration characteristics for a blower impeller. Blower impeller having a cyclically symmetric structure is composed of circumferentially repeated substructures., The whole-structure is partitioned into substructures and then finite element vibration analysis is performed for a substructure using transformed equations for each number of nodal diameter which are derived from discrete Fourier transform in consideration of the cyclic symmetry. natural vibration characteristics for three kinds of models which are blower impeller without support ring with small support ring and with large support ring are numerically analyzed and compared. Accuracy and efficiency of the present method are verified by comparison of results of the analysis with substructure and with whole-structure. Also the results of the analysis by cyclic symmetry module(SOL 115) of MSC/NASTRAN are presented and compared.

• 소음진동
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• 제7권4호
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• pp.637-644
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• 1997

In this paper, a method of finite element analysis is presented for efficient calculation of vibration characteristics of not only simply interconnected structure with cyclic symmetry but also multiply interconnected structure with cyclic symmetry by using discrete Fourier trandform by means of a computer with small memory in a short time. Simply interconnected structure means it is composed of substructures which are adjacent themselves in circumferential direction. First, a mathematical model of multiply interconnected structure with cyclic symmetry is defined. The multiply interconnected structure is partitioned into substructures with the same goemetric configuration and constraint eqauations to be satisfied on connecting boundaries are defined. Nodal displacements and forces are transformed into complex forms through discrete Fourier transform and then finite element analysis is performed for just only a representative substructure. In free vibration analysis, natural frequencies of a whole structure can be obtained through a series of calculation for a substructure along the number of nodal diameter. And in forced vibration analysis, forced response of whole structure can be achieved by using inverse discrete Fourier transform of results which come from analysis for a substructure.

• 대한두경부종양학회지
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• 제37권2호
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• pp.33-41
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• 2021

Background/Objectives: Extra-nodal extension (ENE) is one of the strongest prognosticators in oral cancers. Here we tried to evaluate clinicopathological factors associated with the presence of ENE. Materials & Methods: We retrospectively analyzed clinical information of 120 patients who diagnosed with oral cancer and received curative surgery at our hospital from Mar 2012 to Apr 2020. We comparatively analyzed clinicopathological factors associated with the presence of lymph node (LN) metastasis and ENE, respectively. Results: Variable factors of primary tumor characteristics such as lymphovascular invasion, perineural invasion, largest diameter of tumor, depth of invasion and maximum standardized uptake value were significantly associated with the presence of cervical LN metastasis. The largest diameter of tumor was statistically significant also in multivariate analysis for predicting the LN metastasis. Meanwhile, the association between primary tumor characteristics and the presence of ENE were not statistically significant except the primary tumor size. Importantly, factors associated with LN characteristics including the maximum diameter and number of metastatic LNs were significantly associated with ENE. Conclusion: In this study, several factors affecting cervical LN metastasis and ENE in oral cancer patients were identified. The ENE seems to be influenced by the status of the metastatic LNs, such as the number of metastatic LNs, rather than the characteristics of the primary tumor itself.

• 한국소음진동공학회논문집
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• 제11권9호
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• pp.439-453
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• 2001

This study deals with the free vibration of two identical circular plates coupled with a bounded fluid. An analytical method based on the finite Fourier-Bessel series expansion and Rayleigh-Ritz method is suggested. In the theory, it is assumed that the ideal fluid in a rigid cylindrical container and the two plates are clamped along the plate edges. The proposed method is verified by the finite element analysis using commercial program with a good accuracy. Two transverse vibration modes, namely in-phase and out-of-phase, are observed alternately in the fluid-coupled system when the number of nodal circles increases for the fixed nodal diameter. The effect of gap between the plates on the fluid-coupled natural frequencies sis also investigated.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 춘계학술대회논문집
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• pp.213-219
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• 2001

This paper deals with the free vibration of two identical circular plates coupled with a bounded fluid. An analytical method based on the [mite Fourier-Bessel series expansion and Rayleigh-Ritz method is suggested. In the theory, it is assumed that the ideal fluid is filled in a rigid cylindrical container and the two plates are clamped along the plate edges. The proposed method is verified by the finite element analysis using commercial software with a good accuracy. Two transverse vibration modes, namely in-phase and out-of-phase, are observed alternately in the fluid-coupled system when the number of nodal circles increases for the fixed nodal diameter. The effect of gap between the plates on the fluid-coupled natural frequency is also investigated.

• 한국소음진동공학회논문집
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• 제19권2호
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• pp.208-216
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• 2009

In this paper, we present the equations of motion by which the natural vibration of a rotating annular disk can be analyzed accurately. These equations are derived from the theory of finite deformation and the principle of virtual work. The radial displacements of annular disk at the steady state where the disk is rotating at a constant angular velocity are determined by non-linear static equations formulated with 1-dimensional finite elements in radial direction. The linearlized equations of the in-plane vibrations at the disturbed state are also formulated with 1-dimensional finite elements in radial direction along the number of nodal diameters. They are expressed as in functions of the radial displacements at the steady state and the disturbed displacements about the steady state. In-plane static deformation modes of an annular disk are used as the displacement functions for the interpolation functions of the 1-dimensional finite elements. The natural vibrations of an annular disk with different boundary conditions are analyzed by using the presented model and the 3-dimensional finite element model to verify accuracy of the presented equations of motion. Its results are compared and discussed.

• 소음진동
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• 제8권6호
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• pp.1150-1157
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• 1998

In this Paper, we present an efficient method for finite element vibration analysis of constantly rotating structures with cyclic symmetry, which are deformed to some considerable extent by centrifugal force, Coriolis force and operating load, and vibrate due to several types of exciting forces. A structure with cyclic symmetry is composed of circumferentially repeated substructures with the same geometry. Being only one substructure modeled. the dynamic characteristics of the structure can be analyzed systematically. rapidly and exactly using discrete Fourier transform by means of a computer with small memory.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.717-722
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• 2013

Background: Breast cancer is the most common cancer among women worldwide. The aim of this study was to investigate the relationship between tumor size and axillary lymph node involvement (ALNI) in patients with invasive lesions, to find the best candidates for a full axillary dissection. Additionally, we evaluated the association between tumor size and invasive behavior. The study was based on data from 789 patients with histopathologically proven invasive breast cancer diagnosed in Shohada University hospital in Tehran, Iran (1993-2009). Cinical and histopathological characteristics of tumors were collected. Patients were divided into 6 groups according to primary tumor size: group I ($0.1-{\leq}1cm$), II ($1.1-{\leq}2cm$), III ($2.1-{\leq}3cm$), IV ($3.1-{\leq}4cm$), V ($4.1-{\leq}5cm$) and VI (>5cm). The mean(${\pm}SD$) size of primary tumor at the time of diagnosis was $3.59{\pm}2.69$ cm that gradually declined during the course of study. There was a significant correlation between tumor size and ALNI (p<0.001). A significant positive correlation between primary tumor size and involvement of surrounding tissue was also found (p<0.001). The mean number of LNI in group VI was significantly higher than other groups (p<0.05). We observed more involvement of lymph nodes, blood vessels, skin and areola-nipple tissue with increase in tumor size. We found 15.3% overall incidence of ALNI in tumors ${\leq}2cm$, indicating the need for more investigation to omit full axillary lymph node dissection with an acceptable risk for tumors below this diameter. While in patients with tumors ${\geq}2cm$, 84.3% of them had nodal metastases, so the best management for this group would be a full ALND. Tumor size is a significant predictor of ALNM and involvement of surrounding tissue, so that an exact estimation of the size of primary tumor is necessary prior to surgery to make the best decision for management of patients with invasive breast cancer.

• Journal of Plant Biotechnology
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• 제40권3호
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• pp.147-155
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• 2013

이 실험에서 우리는 더덕의 기내 소비대근형성에 의한 대량생산을 처음으로 보고하였다. 첫번째로, 다경지유도를 위한 싸이토키닌의 효과를 실험하였다. 2.0 $mg{\cdot}L^{-1}$ kinetin 처리는 줄기유도비율(19.1%)뿐만 아니라 줄기의 길이신장(17.1 mm)이 가장 높았다. 두번째로, 절간절편에서 유도되는 기내 소비대근형성에서 탄소급원의 효과를 연구하였다. 비대근의 직경은 1/2 MS배지에 145.9 mM Suc첨가시 증가하였다. 조직학적 분석은 비대근 내에 전분입자가 포함된 유세포의 수가 증가하였다. 게다가 세근은 비대근과 달리 관다발이 피층내에 흩어져 존재하였다. 세번째로, 소비대근의 보전과 발아 촉진을 위하여 $4^{\circ}C$ 저온저장고에 9달 동안 저장 후 이것을 인공상토로 이식한 결과 생존율 75%, 발아율 70%라는 결과를 보였다. 이러한 결과 더덕의 대량 번식은 기내 소비대근 형성에 의해 얻을 수 있고 이러한 방법은 우수클론의 번식 뿐만 아니라 더덕 유전자원 보존을 위해 제공될 수 있을 것으로 사료된다.

• Journal of Gastric Cancer
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• 제6권4호
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• pp.244-249
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• 2006

목적: 수술 전 측정이 가능한 종양의 크기는 위암의 중요한 예후 인자로 생각되고 있으며 크기가 큰 위암은 주위 장기 침범, 광범위 림프절 전이, 원격 전이 등을 동반한 진행성 위암으로 예후가 불량하다고 알려져 있다. 본 연구에서는 종양의 크기를 기준으로 하여 대형위암의 임상 병리학적 분석과 생존율에 영향을 주는 인자들을 분석하였다. 대상 및 방법: 1983년 9월부터 2001년 12월까지 고려대학교 외과학교실에서 위암으로 진단되어 절제술을 시행받은 2,260명을 대상으로 후향적 연구를 시행하였다. 대상군을 장경 8 cm를 기준으로 대형위암 335 (14.8%))예 소형위암 1,925예(85.2%)의 두 군으로 나누어 분석하였다. 대형위암의 임상 병리학적 특성을 분석하기 위하여 두 군 간의 임상 병리학적 인자들을 다변량 분석과 단변량 분석을 시행하였으며 생존은 COx proportional hazards model을 사용하였다. P<0.05인 경우를 통계학적으로 유의한 것으로 판정하였다. 결과: 종양의 위치(P<0.001), 수술 방법(P<0.001), 근치도(P<0.001), 위벽침윤도(P<0.001), 림프절 전이(P<0.001), 분화도(P<0.001) 그리고 타장기의 합병절제율(P<0.001)이 두 군간의 통계학적 차이를 보였다. 대형 위암의 생존율을 Cox proportional hazards model로 분석한 결과 림프절 전이(P<0.001), 근치도(P<0.001), 위벽 침윤도(P=0.010), 수술 방법(P=0.018)과 나이(P=0.033)가 통계적으로 유의한 독립적인 위험인자였다. 결론: 대형위암은 소형위암에 비해 진행된 소견을 보였다. 대형 위암에서 근치절제는 생존율을 향상시키는 매우 중요한 인자로 근치적 절제를 위해 노력이 필요하며 근치적 수술 가능성에 대한 좀더 정확한 수술 전 병기결정에 주의를 기울여야 할 것이다.