• 한국조명전기설비학회:학술대회논문집
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• 한국조명전기설비학회 2007년도 춘계학술대회 논문집
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• pp.224-228
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• 2007

It is focused on a methodology to establish a optimal inspection cycle of electrical facility of railroad Decision method of optimal inspection cycle is a process which establishes maintenance plan for facilities' immanent function as using reliability theory in operation term In order to ensure normal operation in a given condition, the decision method is logical for selecting effective maintenance plan to consider characteristic of system In estimation of failure rate, critical facility is selected firstly. After that, proper distribution function on each facility is decided to investigate distribution function for extraction of failure rate. Next, cost produced by the case that facility's failure is occurred is surveyed. Finally, maintenance method developed until now is investigated, before suitable model for the facility applying maintenance method is developed, and that maintenance decision is made. Therefore, this process is the method to find optimal inspection cycle for reasonable cost and effective reliability on facility.

• 시스템엔지니어링학술지
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• 제6권1호
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• pp.61-68
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• 2010

Generally EPC management system was simply management concept through the normal S/W. Our LNG Plant R&D Center wanted to the excellent management system from the S/W. So We developed the R&D management S/W and EPC management S/W Built in the Microsoft Project Server. Our system made to the customer Requirements. It was just User Interface protocol. But User Interface has more Weak position, because it makes from the MS Project Servers. Ms Projector server make easy to treat the project on the WBS. EPC parts mixed WBS and normally Ms SQL Database. It has very complicated Structures. Now We planed to make the general Database and Ms Project Server, It' means to the S/W Developer and Schedule Manager ability. We will successfully integrate R&D management system and EPC system and other softwares.

• Asian Pacific Journal of Cancer Prevention
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• 제16권7호
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• pp.2665-2669
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• 2015

CD4+CD25+regulatory T cells (Tregs) play a key role in regulation of immnue response and maintenance of self-tolerance. Studies have found Tregs could suppress tumor-specific T cell-mediated immune response and promote cancer progression. Depletion of Tregs can enhance antitumor immunity. Dendritic cells (DCs) are professional antigen-presenting cells and capable of activating antigen-specific immune responses, which make them ideal candidate for cancer immunotherapy. Now various DC vaccines are considered as effective treatment for cancers. The aim of this study was to evaluate variation of Tregs in BALB/C mice with hepatocellular carcinoma and investigate the interaction between tumor-derived Tregs, effector T cells (Teff) and splenic DCs. We found the percentages of Tregs/CD4+ in the peripheral blood of tumor-bearing mice were higher than in normal mice. Tumor-derived Tregs diminished the up-regulation of costimulatory molecule expression on splenic DCs, even in the presence of Teff cells and simultaneously inhibited IL-12 and $TNF-{\alpha}$ secretion by DCs.

• 부모자녀건강학회지
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• 제6권1호
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• pp.59-69
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• 2003

Objective : Recent government policy for encouraging increased birth rate and its historical background were reviewed from the standpoint of a midwife. Suggestions were made for an effective policy to encourage more births. Possible roles of midwives regarding this new policy were also discussed. Methods : Literature reviews and internet research Results : Korea has been very successful in implementing its population control policy since the 1960s. It now considers a policy to encourage increased births due to falling birth rates. There are two opposite sides on this policy. One is positive and the other is negative opinion. The health of women and children should be given top priority in any policy -making or decisions, so that the quality of their lives can be improved. Midwives can be active members in the establishment and implementation of such policies. Conclusion : This policy to increase birth rates can be a good opportunity for midwives to publicize the fact that normal deliveries can be handled economically, efficiently, and safely by them. This will attract more women to employ midwives and use their clinics. If midwifery clinics in the form of a corporation or a consortium with other health care professionals can be established, they could be developed as One-Stop Women's Health Care Centers, where health needs of, not only pregnant women, but all women over the course of their lifetimes can be satisfied.

• 천문학회보
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• 제41권2호
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• pp.43.4-44
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• 2016

The presence of multiple stellar populations is now well established in most globular clusters (GCs) in the Milky Way. The origin of this phenomenon, however, is yet to be understood. In this respect, the study of NGC 2808, an intriguing GC which hosts subpopulations with extreme helium abundances, would help to resolve this problem. In order to investigate chemical abundance patterns among different subpopulations in this GC, we have performed low-resolution spectroscopy for the red-giant-branch (RGB) stars and measured CN & CH bands, and Ca line strength. We have identified at least three subpopulations from the CN abundance distribution. This GC shows CN-CH anti-correlation following the general trend among "normal" GCs. In addition, we have cross-matched our results with the high-resolution data in literature, and found a tight correlation between CN strength and sodium abundance. However, CN is anticorrelated with oxygen abundance, as expected from the well known N(&Na)-O anticorrelation. In this talk, we will discuss the implication of these results.

• BMB Reports
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• 제45권12호
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• pp.677-685
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• 2012

In the process of tumorigenesis, normal cells are remodeled to cancer cells and protein expression patterns are changed to those of tumor cells. A newly formed tumor microenvironment elicits the immune system and, as a result, a humoral immune response takes place. Although the tumor antigens are undetectable in sera at the early stage of tumorigenesis, the nature of an antibody amplification response to antigens makes tumor-associated autoantibodies as promising early biomarkers in cancer diagnosis. Moreover, the recent development of proteomic techniques that make neo-epitopes of tumor-associated autoantigens discovered concomitantly has opened a new area of 'immuno-proteomics', which presents tumor-associated autoantibody signatures and confers information to redefine the process of tumorigenesis. In this article, the strategies recently used to identify and validate serum autoantibodies are outlined and tumor-associated antigens suggested until now as diagnostic/prognostic biomarkers in various tumor types are reviewed. Also, the meaning of autoantibody signatures and their clinical utility in personalized medicine are discussed.

• Molecules and Cells
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• 제37권12호
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• pp.851-856
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• 2014

ATAD2, a remarkably conserved, yet poorly characterized factor is found upregulated and associated with poor prognosis in a variety of independent cancers in human. Studies conducted on the yeast Saccharomyces cerevisiae ATAD2 homologue, Yta7, are now indicating that the members of this family may primarily be regulators of chromatin dynamics and that their action on gene expression could only be one facet of their general activity. In this review, we present an overview of the literature on Yta7 and discuss the possibility of translating these findings into other organisms to further define the involvement of ATAD2 and other members of its family in regulating chromatin structure and function both in normal and pathological situations.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 추계학술대회 논문집
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• pp.494-499
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• 2007

The ballast, one of a track components, plays an essential role as intermedium in transmitting train traffic-load to subgrade safely, and deterioration of ballast caused by cumulative load effects growth of track irregularity. Especially in the case of Gyeongbu high-speed railway, the deteriorating speed of ballast by dynamic vibration is faster than conventional line because KTX is longer than normal trains in length and it's velocity is very fast with high speed of 300km/h as well. In addition, ballast is a nonlinear material contrary to ordinary metal which has homogeneous property and this property of ballast may cause transformation of ballast. Therefore the theoretical modeling of ballast is quite complicated and it is hard to ensure the reliability of the result. The objective of this paper is to examine the availability of GPR(Ground Penetrating Radar) in estimating the thickness and the degree of deterioration of ballast. First, We figured out the principle of GPR which is the technique of evaluating the condition of ballast and then analyzed data which were measured at Gyeongbu high-speed railway where KTX is running now.

• Nuclear Engineering and Technology
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• 제34권5호
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• pp.502-516
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• 2002

Wolsong NPP are CANDU6 type reactors and there are 4 CANDU6 type reactors in commercial operation. CANDU type reactors require on-power refuelling by two remote controlled F/Ms (Fuelling Machines). Most of channels, fuel bundles are float by channel coolant flow and move toward downstream, however in about 30% of channels the coolant flow are not sufficient enough to carry fuel bundles to downstream. For those channels a special device, FARE (Flow Assist Ram Extension) device, is used to create additional force to push fuel bundles. It has been showing that during fuelling operation of some channels the channel coolant flow rate is reduced below specified limit (80% of normal), and consequently trip alarm signal turns on. This phenomenon occurs on selected channels that are instrumented for the channel flow and required to use the FARE device for refuelling. Hence it is believed that the FARE device causes the problem. It is also suspected that other channels that do not use the FARE device for refuelling might also go into channel flow low state. The analysis revealed that the channel How low occurs as the FARE device is introduced into the core and disappears as the FARE device is removed from the core. This paper presented the FARE device behavior, detailed fuelling operation sequence with the FARE device and effect on channel flow low phenomena. The FARE device components design changes are also suggested, such as increasing the number or now holes in the tube and flow slots in the ring orifice.

• 콘크리트학회논문집
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• 제12권4호
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• pp.49-58
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• 2000

There are many methods to improve the performance of concrete. Especially, granuated blast furnace slag. by-products used in concrete as the replacement material of cement, could contribute to improve the fluidity, resistance of chemical attack and strength of concrete. Also, it could contribute to decrease the rate of generating hydration heat, in addition to cost-down of concrete and prevention of enviromental pollution. Therefore, in order to establish the systemical application of granuated blast furnace slag in normal concrete, the engineering properties of concrete, such as fluidity, strength, setting and hydration properties etc.. was evaluated. In this study, replacement ratio of granuated blast furnace slag was 0, 30, 50, 70(%), and target slump was 8, 12, 15, 18(cm). Results from the experiment, granuated blast furnace slag showed the outstanding effects of improving the engineering properties of concrete. From now on, positive application of granuated blast furnace slag is expected in the point of improving the performance and cost-down of concrete.