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Market expectations of future progressive lenses through comparison of general progressive lenses and free-form progressive lenses (일반 누진다초점렌즈와 프리폼 누진다초점렌즈의 비교를 통한 향후 누진다초점렌즈 시장의 예측)

  • Lee, Jeung-Young;Park, Jeong-Sik;Jang, Woo-Yeong
    • Journal of the Korea society of information convergence
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    • v.6 no.2
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    • pp.57-60
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    • 2013
  • In this paper, We compared middle-aged wearer's satisfaction of progressive multifocal lens and free-form progressive multifocal lens wearers, and investigate the direction of improvement of progressive multifocal lens. We tried to predict the development direction of progressive lenses in the future. The results of the survey, satisfaction of free-form progressive multifocal lens wearers was high, compared to normal progressive lenses. The price of free-form progressive multifocal lens is expensive compared to the nomal progressive multifocal lens, but provides a wide view than nomal progressive lenses. It was confirmed that there is sufficient merit. because it can be made in individual customized to the wearer. In the near future, It is expected that free-form progressive multifocal lenses is the most popular progressive multifocal lenses to middle-aged wearers.

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Tumor Cell Clone Expressing the Membrane-bound Form of IL-12p35 Subunit Stimulates Antitumor Immune Responses Dominated by $CD8^+$ T Cells

  • Lim, Hoyong;Do, Seon Ah;Park, Sang Min;Kim, Young Sang
    • IMMUNE NETWORK
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    • v.13 no.2
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    • pp.63-69
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    • 2013
  • IL-12 is a secretory heterodimeric cytokine composed of p35 and p40 subunits. IL-12 p35 and p40 subunits are sometimes produced as monomers or homodimers. IL-12 is also produced as a membrane-bound form in some cases. In this study, we hypothesized that the membrane-bound form of IL-12 subunits may function as a costimulatory signal for selective activation of TAA-specific CTL through direct priming without involving antigen presenting cells and helper T cells. MethA fibrosarcoma cells were transfected with expression vectors of membrane-bound form of IL-12p35 (mbIL-12p35) or IL-12p40 subunit (mbIL-12p40) and were selected under G418-containing medium. The tumor cell clones were analyzed for the expression of mbIL-12p35 or p40 subunit and for their stimulatory effects on macrophages. The responsible T-cell subpopulation for antitumor activity of mbIL-12p35 expressing tumor clone was also analyzed in T cell subset-depleted mice. Expression of transfected membranebound form of IL-12 subunits was stable during more than 3 months of in vitro culture, and the chimeric molecules were not released into culture supernatants. Neither the mbIL-12p35-expressing tumor clones nor mbIL-12p40-expressing tumor clones activated macrophages to secrete TNF-${\alpha}$. Growth of mbIL-12p35-expressing tumor clones was more accelerated in the $CD8^+$ T cell-depleted mice than in $CD4^+$ T cell-depleted or normal mice. These results suggest that $CD8^+$ T cells could be responsible for the rejection of mbIL-12p35-expressing tumor clone, which may bypass activation of antigen presenting cells and $CD4^+$ helper T cells.

CEPHALOMETRIC ANALYSIS FOR CHILDREN WITH NORMAL OCCLUSION IN THE PRIMARY DENTITION (정상교합을 가진 유치열기 아동의 두부방사선 계측학적 연구)

  • Suh, Moon-Sun;Son, Heung-Kyu;Baik, Hyung-Sun;Choi, Hyung-Jun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.1
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    • pp.109-118
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    • 2005
  • In the field of pediatric dentistry, comparison and analysis of cephalogram values of children are important fir evaluation of growth and development, and are essential to evaluate the craniofacial form and growth pattern for early diagnosis of malocclusion. For this, cephalographic norm values are important, but not many studies on the primary dentition exist. To compare the past norm values of normal occlusion in the primary dentition with current norms, preschool children, 4 to 5 years of age, with normal occlusion in the primary dentition who visited our hospital were examined. Among these children, 46 children with normal facial form and developmental status were chosen for evaluation of cephalogram values. The following results were as follows: 1. For skeletal values, the angular values showed no significant differences between males and females, and the linear values were generally greater in males than females. 2. SNA was $81.3^{\circ}$, SNB was $76.6^{\circ}$ and ANB difference was $4.7^{\circ}$. 3. The ratio for Mandibular body length to Anterior cranial base length was 0.9 : 1 for both male and female and the ratio for posterior facial height to anterior facial height was 61.4 % for male, 62.0 % for female. 4. For dental values, IMPA was $84.2^{\circ}$ and UA to SN was $90.8^{\circ}$. 5. The upper lip to Ricketts esthetic line was positioned 2.6 mm anteriorly, and the lower lip to Ricketts esthetic line was positioned 2.5 mm anteriorly.

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DEVELOPMENT OF THE KOREAN FORM OF MORAL DEVELOPMENT INVENTORY FOR ADOLESCENTS (한국판 청소년용 도덕발달수준 평가도구의 개발)

  • Shin, Jee-Yong;Cho, Soo-Churl
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.8 no.2
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    • pp.183-198
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    • 1997
  • Objects:This study was carried out to develop the Korean form of Moral Development Inventory for Adolescents designed to assess the principled morality in adolescents. And the auther also intended to find the demographic variables that influence the moral development. Methods:The Korean form inventory was applied to 507 middle and high school adolescents, and retest was done in 42 second year middle school adolescents with 3 weeks interval. Together this inventory, short form of Rest moral development which had been proved its reliability and validity, were administered to the all subjects for concurrent validity. And then the author examined whether this inventory discriminates between conduct disorder patients, psychiatric controls and normal controls in the level of moral development. Results:Test-retest reliability and internal consistency were very satisfactory. Concurrent validity with this inventory was also high level. And conduct disorder patients were scored significant lower than psychiatric and normal controls in the level of principled morality. The mean PM scores did not show significant difference according to the variables such as sex, birth order and religion. But there was significant difference according to the educational level of mother and places. Conclusions:These results indicate that the Korean form of Moral Development Inventory is a reliable and valid rating inventory to assess the moral development level in Korean adolescents.

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A Study on Development of Questionaire for Use in Epidmiologic Survey on Respiratory Illness in Korea (호흡기계(系) 질환의 역학적(疫學的) 조사방법 게발에 관한 연구(II) -한국(韓國) 실정에 맞는 설문조사서 개발-)

  • Ahn, Yoon-Ok;Kim, Keun-Youl;Kwon, E-Hyock
    • Journal of Preventive Medicine and Public Health
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    • v.15 no.1
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    • pp.57-73
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    • 1982
  • Questionaires on symptoms of respiratory disease have been used in Korea to elicit the probable health effects of air pollution in epidemiologic studies: The objectives of such studies often include comparing prevalence of symptoms of respiratory system between different population groups or between the same population groups, at different times. Unfortunately, little attention has, been paid to standardization of those questionaires, whether those are Korean. versions or not. Furthermore, no attempt to develop Korean ,questionaire on respiratory symptoms and relevant information has been made. Followed by 'a comparative study on responses to Korean version questionaires(English origin) of CMI, MRC, and ATS-DLD-78' two types of questionaires on respiratory symptoms and relevant information for Korean adult, which are short form (SUN-81-AS) and long forms (optional questions are added to the short one, SUN-81-AL), have been designed suitable to Korean background by authors (see Annex). The self-administered and closed-question questionaire were tested their validity and reliability by administration to l80 normal adults (medical and nursing students) and 60 clinical patients of Seoul National University Hospital, with spirometric exam. The results obtained and conclusions drawn are as follow: 1. It took less than 10 minutes to complete the questionaire SNU-81-AS and SNU-81-AL. 2. The test-retest reliability of each questions in AS and AL ,were observed as 92.7% and 92.1%, respectively. And all of the level of agreement are statistically significant with kappa statistic. 3. In addition to higher prevalence rate of symptoms in patients group compared, with, normal. group, the correlations between FEV 1.0/FVC predictive value(%) and number of symptoms were statistically significant inpatients group (See Fig. 1 and, Table 7). 4. The answer rate to optional questions in AL form among those who are not to do was about 10%, while the no-answer rate among who are to do was about 15% in Normal (medical and nursing students) group. 5. From the viewpoints of validity and reliability, the new Korean questionaire (SNU-81-AS and AL) developed by authors are to be recommendable to use in epidemiologic studies on respiratory illness in Korea. The self-administration, however, of optional questions in AL form may not assure the quality of data gathered.

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Development of Short Form of the Korean Version- the Boston Naming Test (K-BNT-15) Based on Item Response Theory (문항반응이론을 적용한 한국판 보스톤 이름대기 검사 단축형(K-BNT-15) 개발)

  • Kim, HyangHee;Kim, Soo Ryon
    • The Journal of the Korea Contents Association
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    • v.13 no.12
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    • pp.321-327
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    • 2013
  • Impaired naming difficulty is common in normal elderly as well as in patients with neurological impairment. The 60-item Korean version-Boston Naming Test(K-BNT) is one of the most commonly used test for measuring confrontational naming ability. However, age-related cognitive decline may make the elderly difficult concentrating during the 60-item test, therefore, item reduction of the K-BNT would improve test validity and reliability. Thus, the purpose of this study was to develop a short form of the K-BNT based on Item Response Theory(IRT). Considering item-fit index, sex factor, and item difficulty through Rasch analysis, the 15-item K-BNT(i.e., K-BNT-15) was developed. Via administration of the K-BNT-15, we observed age-related decline in naming ability and significantly different performance between the normal elderly and patients with mild cognitive impairment. This study demonstrates the utility of IRT for developing a short-form language evaluation tool. The K-BNT-15 can be effective as a language screening tool to differentiate between normal aging and pathological diseases.

Development of Reminiscence Function Scale-Short Form: A Study on Reliability and Validity (단축형 회상기능척도(Reminiscence Function Scale-Short Form) 개발 : 신뢰도 및 타당도 연구)

  • Cha, Yu-Jin
    • The Journal of the Korea Contents Association
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    • v.16 no.6
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    • pp.225-235
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    • 2016
  • This study aims at developing Reminiscence Function Scale-Short Form(RFS-S) and verifying it as a supplemental diagnosis instrument to judge differences between normal and mild cognitive impairment and useful measure to rate effects of reminiscence therapy in the clinical field through internal consistency reliability and criterion validity. The study also aims at figuring out factors affection reminiscence function by figuring out demographic features of RFS-S. The research subjects were the control group of 60 normal people and experimental group of 58 people with mild cognitive impairment and both groups were over 65 years old. For internal consistency reliability(Cronbach's alpha) between questions was reliable with 0.63. Convergent validities of RFS-S with SRT and CDR-SB were 0.20(p<.05) and -0.25(p<.001), respectively, as both showed significant correlations. As a result of criterion validity to analyze AUROC, it was 0.68(p<.001) and less accurate. Its optimal cut-off points were 17 and sensitivity according to them was 0.59, and specificity was 0.72, respectively. However, reminiscence function according to demographic variables did not show any significant differences. Therefore, it is expected that RFS-S will be used as a supplemental diagnosis instrument with higher reliability and validity for discerning differences between normal and mild cognitive impairment and as a useful one to verify effects of reminiscence therapy.

A Cohesive Surface Separation Potential

  • Lee, Youngseog;Kim, Kwang-Soo
    • Journal of Mechanical Science and Technology
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    • v.16 no.11
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    • pp.1435-1439
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    • 2002
  • This paper presents a form of the cohesive surface separation potential, which can produce potential curves by varying a single dimensionless parameter. Results show that a partial modification of Xu and Needleman's (1994) cohesive surface separation potential makes it possible to present the other potential corves as a special case as long as the normal separation is concerned. The proposed potential may describe interfacial debonding-crack initiation and growth-character of materials and, through numerical simulation, provide an insight for the effect of different cohesive surface separation potentials on the interfacial debonding.

SEMI-INVARIANT SUBMANIFOLDS OF CODIMENSION 3 IN A COMPLEX HYPERBOLIC SPACE

  • KI, U-HANG;LEE, SEONG-BAEK;LEE, AN-AYE
    • Honam Mathematical Journal
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    • v.23 no.1
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    • pp.91-111
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    • 2001
  • In this paper we prove the following : Let M be a semi-invariant submanifold with almost contact metric structure (${\phi}$, ${\xi}$, g) of codimension 3 in a complex hyperbolic space $H_{n+1}{\mathbb{C}}$. Suppose that the third fundamental form n satisfies $dn=2{\theta}{\omega}$ for a certain scalar ${\theta}({\leq}{\frac{c}{2}})$, where ${\omega}(X,\;Y)=g(X,\;{\phi}Y)$ for any vectors X and Y on M. Then M has constant eigenvalues correponding the shape operator A in the direction of the distinguished normal and the structure vector ${\xi}$ is an eigenvector of A if and only if M is locally congruent to one of the type $A_0$, $A_1$, $A_2$ or B in $H_n{\mathbb{C}}$.

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Nonlinear section model for analysis of RC circular tower structures weakened by openings

  • Lechman, Marek;Stachurski, Andrzej
    • Structural Engineering and Mechanics
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    • v.20 no.2
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    • pp.161-172
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    • 2005
  • This paper presents the section model for analysis of RC circular tower structures based on nonlinear material laws. The governing equations for normal strains due to the bending moment and the normal force are derived in the case when openings are located symmetrically in respect to the bending direction. In this approach the additional reinforcement at openings is also taken into account. The mathematical model is expressed in the form of a set of nonlinear equations which are solved by means of the minimization of the sums of the second powers of the residuals. For minimization the BFGS quasi-Newton and/or Hooke-Jeeves local minimizers suitably modified are applied to take into account the box constraints on variables. The model is verified on the set of data encountered in engineering practice. The numerical examples illustrate the effects of the loading eccentricity and size of the opening on the strains and stresses in concrete and steel in the cross-sections under consideration. Calculated results indicate that the additional reinforcement at the openings increases the resistance capacity of the section by several percent.