• Journal of Physiology & Pathology in Korean Medicine
• /
• v.21 no.1
• /
• pp.104-110
• /
• 2007

Aralia contientalis show several beneficial effects including anti-oxidant effects. Aralia contientalis is used as a therapeutic agent to stop haemorrhages and a tonic to promoted health in Korean and Chinese medicine. The pharmacokinetic profiles of the main Aralia contientalis is still not accurately investigated. In present study, I examined the effects of water extracts of Aralia contientalis on high cholesterol diet atherosclerosis-induced rats in serum and abdominal aorta. A total of 3-week old 9 male rats of Sprague-Dawley were divided into 3 groups and fed with the basal diet (normal group), high cholesterol diet (atherosclerosis induced group) for 8 weeks, high cholesterol diet supplemented with water extracts of Aralia contientalis (Aralia contientalis group) for 2 weeks. And rats were sacrificed, serum lipid level, abodominal aortic anti-oxidant activities and lipid peroxide were measured. These results indicated that serum total cholesterl, LDL-cholesterol, triglycerides concentration significently lowered in Aralia contientalis group than high cholesterol diet group. But HDL-cholesterol concentraion significently higher in Aralia contientalis group than high cholesterol diet group.

• Korean Journal of Clinical Laboratory Science
• /
• v.41 no.1
• /
• pp.1-5
• /
• 2009

The Platelet Function Analyzer (PFA)$^{(R)}$-100 measures the ability of platelets activated in a high-shear environment to occlude an aperture in a membrane treated with collagen and epinephrine (CEPI) or collagen and ADP (CADP). The time taken for the flow across the membrane to stop (closure time, CT) is recorded. The aim of this study was to assess the potential of the PFA$^{(R)}$-100 as a primary clinical screening tool using the wide spectrum of clinical samples assessed for platelet function as well as to perform the optimal algorithm for the use of PFA$^{(R)}$-100. We established the reference interval in 460 hospital inpatients defined as having normal platelet function based on classical laboratory tests. The reference interval by using the range $5^{th}$ and $95^{th}$ percentile was 84~251 seconds for males CEPI-CT and 85~249 seconds for females CEPI-CT. A total of 1,200 inpatients were enrolled to identify impaired hemostasis before surgical interventions. The abnormal group showing prolonged CEPI-CT was 303 cases (18.9%). Only 3 cases had both abnormal CEPI-CT and CADP-CT. Several factors including sample errors, drugs, hematologic abnoralities were contributed to unexpected prolonged CEPI-CT for screening test. The von Willebrand factor (vWF:Ag) assay was performed only in one patient to verify the algorithm for the use of PFA$^{(R)}$-100. The PFA$^{(R)}$-100 was sensitive and rapid method for primary screening test of platelet dysfunction, so we can substitute it for the bleeding time in routine clinical practice.

• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.43 no.5 s.347
• /
• pp.147-155
• /
• 2006

In this paper, we propose a new Mushroom-like PBG concepts for designing with forbidden frequency band-gap at low frequency. These design rules are based on enhancing the capacitance per unit area using modified top-patch of mushroom PBG with no increase on the overall thickness of the substrate board. Also, in this paper, a new approach to suppress the surface wave from antenna is proposed by embedding compact mushroom PBG in the substrate. Comparisons between the results from a conventional patch antenna to a patch antenna on a PBG substrate show that the reduction in the surface wave level is remarkable. This can be observed in the radiation pattern and the maximum gain. The maximum gain for reference patch antenna is $6.43dB{\imath}$ at 5.37 GHz, while the maximum gain for the patch antenna with normal mushroom and vane mushroom PBG is $7.24dB{\imath}\;and\;7.53dB{\imath}$at 5.14 GHz. The back radiation is also considerably reduced; this will lead, of course, to an increase in the antenna efficiency.

• Journal of the Korean Applied Science and Technology
• /
• v.32 no.2
• /
• pp.181-187
• /
• 2015

We found that we could manage the crystal size of active material by controlling the temperature on curing procedure which is one of the process to produce lead acid battery. The active material causes to improve initial efficiency and durability for the batteries. 3BS from the active materials after curing process is better for initial efficiency. 4BS is not good for the initial efficiency but is better than 3BS in durability by 48%. Accroding to our test results of DOD17.5% life test which is for evaluating of automobile applied ISG system, it is not suitable for flooded lead acid battery which is used for the normal automobil but it is proper to AGM lead acid battery.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.35 no.5
• /
• pp.661-670
• /
• 2006

Selenium (Se) obtained from dietary sources including cereals, grains and vegetables is an essential micronutrient for normal function of the body. Plants convert Se into selenomethionine and incorporate it into proteins in place of methionine, while higher animals synthesize selenoproteins containing selenocysteine. Excessive Se in the body is methylated stepwise to methylated selenium metabolites from selenide. Both inorganic and organic forms of selenium can be the nutritional sources in human, and they are transformed to selenide and then the amino acid selenocysteine attached to a specific $tRNA^{ser(sec)}$. The selenocysteine (Sec) is incorporated into selenoprotein sequences by the UGA codon. The decoding of UGA as Sec requires specific mechanisms because UGA is normally read as a stop codon: cis-acting sequences in the mRNA (the selenocysteine insertion sequence, SECIS, within the 3'untranslated region) and trans -acting factors dedicated to Sec incorporation are required for incorporation of Sec during translation of selenoprotein mRNAs. Approximately 25 selenoproteins have been identified in mammals. Several of these, including glutathione peroxidases, thioredoxin reductases and selenoprotein P, have been purified or cloned, allowing further characterization of their biological function. The antioxidant properties of selenoproteins help prevent cellular damage from free radicals which may contribute to the development of chronic disease such as cancer and heart disease. Other selenoproteins have important roles in regulation of thyroid function and play a role in the immune system. Daily selenium iatake was reported to be $42.0{\pm}16.9{\mu}g/day$ in Korean adult women. This review focuses on the metabolism and biological functions of selenium, and the nutritional status of selenium in the Korean population.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.18 no.5
• /
• pp.1505-1511
• /
• 2004

Inhibition of angiotensin converting enzyme (ACE) activity is one of the common antihypertensive methods functioned by drugs such as captopril, lisinopril and enalapril to serve as inhibitors of ACE. This study was designed to compare the effects of enalapril, an angiotensin-converting enzyme inhibitor and GLM002, an oriental medicine, on tail systolic pressure, aorta and plasma properties in spontaneously hypertensive rats (SHR) after 4 weeks of treatment. During the treatment, blood pressure was depressed to normal in GLM002 and enalapril groups. The treatments of enalapril and GLM002 were discontinued in 4 weeks. One week after the treatment stop, systolic blood pressure was smoothly increased in both groups; the increment of blood pressure was slightly greater in GLM002-SHR, but the increment of plasma ACE activity was proportionately similar in each group. In the aspects of the triglyceride, HDL and total cholesterol level, those levels were slightly different among each group. We also conducted clinical dosage of GLM002 to the patients who have mild and severe hypertension for approximately 7 weeks. Clinical treatments also showed remarkable efficiencies on blood pressure (systolic blood pressure, diastolic blood pressure), complete blood count (CBC) routine, differ count (NEUTRO, LYM, MONO, EOS and BASO) and R-chemistry. We conclude that GLM002, like already proven enalapril, plays a role as an angiotensin-converting enzyme inhibitor, and can be suggested as a drug candidate for curing hypertension.

• Journal of Korean Society of Transportation
• /
• v.28 no.6
• /
• pp.85-97
• /
• 2010

The present study aims at estimating the model of bus bunching duration along with its influential determinants in an attempt to understand the status of bus bunching being created by buses from various routes converging into one bus stop. To do so, the duration analysis, a well-known survival analysis, was adopted in order to capture the distribution of duration time as for 8 base lines, accordingly developing the model best fit for weibull distribution. Key attention to draw out the duration time model for bus bunching phenomena was laid, by analyzing 18 impact factors, on such criterion variables as number of berth, number of bus line in each berth and maximum capacity of on-and-off passengers in each line. Comparison in two typical types of bus lane was made between bus-only center lane(Dobong Mia-ro) and normal street-side lane(Tongil Euiju-ro). In this regard, the study, based on the model as above, suggested appropriate alternatives to improve the bus operation by effectively controlling bus bunching.

• Journal of the Korean Society of Safety
• /
• v.32 no.6
• /
• pp.22-28
• /
• 2017

According to the National Fire Data System (NFDS), more than 5,000 vehicle fires have occurred every year for the last 10 years. Vehicle fires are primarily caused by mechanical (breaking system and engine), electrical (wiring and battery), and chemical (oil and fuel gas leakage) problems. The electrical factor has increased with the installation of driver convenience equipment. For example, today, the black box is widely used to provide video data recording of motor vehicle accidents. The black box consists of a front camera, rear camera, and wires. The black box wires are directly connected to the junction box or fuse box from the start battery that operates to provide normal on power supplying for engine stop. It is extremely dangerous when the wires short circuit due to insulation aging, mechanical and electrical stress, etc. In this study, the black box wiring fire risk have been analyzed and investigated when the steady state and abnormal operations, and under the following conditions: wiring arrangements with a high temperature condition, insulation aging, poor contact, and short circuits. The results showed that black box wiring short circuits had a higher fire risk than the other fire hazard elements. To prevent fire hazards caused by black box wiring, the black boxes must be installed by qualified service personnel. Do not modify the wiring, remove the fuse and secure the wiring using cable ties or insulation tape.

• Clinical and Experimental Pediatrics
• /
• v.53 no.5
• /
• pp.634-638
• /
• 2010

Purpose: In Kyung Hee East-West Neo Medical Center, Seoul, Korea, efforts to raise rooming-in care success rate have been undertaken since when the hospital was established in 2006. We intended to analyze our experience over the past 3 years of period and to discuss the advantages of rooming-in. Methods: We analyzed the rooming-in practice rate, failure rate, and the breast feeding rate. Subjects were 860 normal healthy neonates from June 2006 to June 2009. Results: Among these 860 cases, 83 babies were required separation out of rooming-in in the middle of the course. Among these 83 cases, 70 cases had to stop the course due to poor condition of babies and 13 cases due to maternal condition. 70 cases of infant's causes consist of 68 cases of NICU admission and 2 cases of poor feeding support. The other 13 cases of separation include refusal by maternal condition. Therefore the success rate of rooming-in for the last 3 years was 90.3%, that is 777 cases among the total 860 cases. The percentage of exclusive breast feeding was 64%, that of mixed feeding with breast and formula feeding was 25%, and formula feeding only was 11%. Conclusion: We experienced successful rooming-in care for the last 3 years. Nursery facilities should educate and encourage the advantages of rooming-in, including the good formation of attachment between mother and infant, emotional stability, protection from infection, and increased breast feeding rate so that rooming-in care can be fully established.

• Journal of the Ergonomics Society of Korea
• /
• v.26 no.4
• /
• pp.25-31
• /
• 2007

The purpose of this study was to investigate the strength and endurance of the deep neck flexor muscles in individuals with work-related neck pain. Subjects consisted of two groups: twenty industrial workers with neck pain and twenty age-matched healthy subjects. To evaluate the strength and endurance of deep cervical flexors, maximum voluntary contractile strength (MVCS) and a sustained time at sub-maximal voluntary contractile strength (SMVCS) (80% and 50% of MVCS) were measured using a pressure biofeedback unit and a stop watch in supine. The MVCS of deep neck flexor muscles was 29.67${\pm}$4.56 in neck pain group and 54.27${\pm}$6.78㎜Hg in normal group. The sustained time at 80% SMVCS was 12.42${\pm}$2.64 seconds and 55.12${\pm}$12.76 seconds in the groups with and without neck pain. The sustained time at 50% SMVCS was 25.40±5.88 seconds and 109.70${\pm}$31.50 seconds in the groups with and without neck pain. The difference of the lower jaw position was 16.75${\pm}$3.57㎜ and 23.03${\pm}$2.51㎜. The MVCS, endurance at the two sub-maximal levels and the difference of the lower jaw position were significantly greater in the group without neck pain than with neck pain (p$<$0.05). The findings indicate that the maximal strength and endurance of the deep neck flexors were decreased in the workers with neck pain compared to those without neck pain. Therefore, it is necessary to include strengthening and endurance exercises of the deep neck flexor muscles in therapeutic program of work-related musculoskeletal disorders involving neck pain.