• 대한한의학회지
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• 제42권1호
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• pp.75-98
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• 2021

Objectives: The purpose of this study is to investigate the characteristics, validity, and reliability of non-radiological assessment tools of scoliosis that have been studied so far. Methods: Electronic databases including Pubmed, Cochrane Library, CNKI, Science On, RISS, OASIS were searched by keywords including 'scoliosis assessment', 'scoliosis screening', 'physical examination', 'functional measurement', 'photography', and 'smartphone'. Results: 32 articles using radiation-free assessments were identified from 1,011 records. The mostly used non-radiological methods were Surface topography, Scoliometer, Ultrasound, Digital Infrared Thermal Imaging, and Photography. The other methods were Gait analysis, 3D depth sensor imaging, and Low intensity electromagnetic scan. Conclusions: It was found that non-radiological assessment tools might reduce the number of radiographs taken in scoliosis patients. To increase the reliability and validity, further research on the measurement tools of scoliosis will be needed.

• Korean Journal of Radiology
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• 제24권4호
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• pp.284-293
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• 2023

Objective: To validate a simplified ordinal scoring method, referred to as modified length-based grading, for assessing coronary artery calcium (CAC) severity on non-electrocardiogram (ECG)-gated chest computed tomography (CT). Materials and Methods: This retrospective study enrolled 120 patients (mean age ± standard deviation [SD], 63.1 ± 14.5 years; male, 64) who underwent both non-ECG-gated chest CT and ECG-gated cardiac CT between January 2011 and December 2021. Six radiologists independently assessed CAC severity on chest CT using two scoring methods (visual assessment and modified length-based grading) and categorized the results as none, mild, moderate, or severe. The CAC category on cardiac CT assessed using the Agatston score was used as the reference standard. Agreement among the six observers for CAC category classification was assessed using Fleiss kappa statistics. Agreement between CAC categories on chest CT obtained using either method and the Agatston score categories on cardiac CT was assessed using Cohen's kappa. The time taken to evaluate CAC grading was compared between the observers and two grading methods. Results: For differentiation of the four CAC categories, interobserver agreement was moderate for visual assessment (Fleiss kappa, 0.553 [95% confidence interval {CI}: 0.496-0.610]) and good for modified length-based grading (Fleiss kappa, 0.695 [95% CI: 0.636-0.754]). The modified length-based grading demonstrated better agreement with the reference standard categorization with cardiac CT than visual assessment (Cohen's kappa, 0.565 [95% CI: 0.511-0.619 for visual assessment vs. 0.695 [95% CI: 0.638-0.752] for modified length-based grading). The overall time for evaluating CAC grading was slightly shorter in visual assessment (mean ± SD, 41.8 ± 38.9 s) than in modified length-based grading (43.5 ± 33.2 s) (P < 0.001). Conclusion: The modified length-based grading worked well for evaluating CAC on non-ECG-gated chest CT with better interobserver agreement and agreement with cardiac CT than visual assessment.

• 방사성폐기물학회지
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• 제17권1호
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• pp.95-106
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• 2019

원전 해체를 준비함에 있어 정성적 또는 정량적 위험도 평가는 필수요소이다. 해체 공정간 발생하는 방사선학적 및 비방사선학적 위험요소는 해체 작업자 및 대중의 안전을 보장하기 위해 사전에 평가되어야 한다. 현재 해체 경험이 많은 미국의 기존 사업자들 및 NRC의 경우 위험의 중대성만 평가하는 결정론적 위험도 평가에 집중하고 있다. 하지만 최근 IAEA는 위험도 매트릭스를 활용한 위험도평가를 결정론적 위험도 평가의 대체안으로 제안하고 있다. 따라서 본 연구에서는 위험도평가에 앞서 해체 공정 별 해체 활동을 Risk Breakdown Structure에 맞추어 정리하였고, 미국 20여개 해체 원전에서 해체 공정별 위험도 평가 시행 중 선정한 해체 활동간 잠재적 사고를 해체 활동에 맞게 체계적으로 정리하였다. 그리고 복합 리스크 매트릭스를 개발 및 활용하여 해체 공정간 방사선학적 및 비방사선학적 위험요소의 위험도를 평가하여 정량적으로 수치화 하였다.

• Nuclear Engineering and Technology
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• 제54권2호
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• pp.770-780
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• 2022

In 1993 the University of Extremadura initiated the design, construction and management of the Radiological Alert Network of Extremadura (RAREx). The goal was to acquire reliable near-real-time information on the environmental radiological status in the surroundings of the Almaraz Nuclear Power Plant by measuring, mainly, the ambient dose equivalent. However, the phased development of this network has been carried out from two points of view. Firstly, there has been an increase in the number of stations comprising the network. Secondly, there has been an increase in the number of monitored parameters. As a consequence of the growth of RAREx network, large data volumes are daily generated. To face this big data paradigm, software applications have been developed and implemented in order to maintain the indispensable real-time and efficient performance of the alert network. In this paper, the description of the current status of RAREx network after 30 years of design and performance is showed. Also, the performance of the graphing software for daily assessment of the registered parameters and the automatic on real time warning notification system, which aid with the decision making process and analysis of values of possible radiological and non-radiological alterations, is briefly described in this paper.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2010년도 학술논문요약집
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• pp.51-52
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• 2010

• 한국방사선학회논문지
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• 제5권6호
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• pp.377-381
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• 2011

이 연구의 목적은 일반방사선촬영에서 입사표면선량에 대하여 나노도트선량계의 측정값과 Non Dosimeter Dosimetry-Method(NDD-M)의 계산값과 비교 평가하는 데 있다. 입사표면선량들의 측정과 계산은 두부(AP), 복부(AP), 골반(AP), 흉추(AP)와 요추(AP)에 대하여 수행하였다. 결과로서, 계산값에 대한 측정값의 상대비들은 각 부위에 대하여 1.5-2.1을 얻었다. 재현성은 변동계수로서 0.035를 얻었다.

• Toxicological Research
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• 제30권3호
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• pp.211-220
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• 2014

Resveratrol has received considerable attention as a polyphenol with various biological effects such as anti-inflammatory, anti-oxidant, anti-mutagenic, anti-carcinogenic, and cardioprotective properties. As part of the overall safety assessment of HS-1793, a novel resveratrol analogue free from the restriction of metabolic instability and the high dose requirement of resveratrol, we assessed genotoxicity in three in vitro assays: a bacterial mutation assay, a comet assay, and a chromosomal aberration assay. In the bacterial reverse mutation assay, HS-1793 did not increase revertant colony numbers in S. typhimurium strains (TA98, TA100, TA1535 and TA1537) or an E. coli strain (WP2 uvrA) regardless of metabolic activation. HS-1793 showed no evidence of genotoxic activity such as DNA damage on L5178Y $Tk^{+/-}$ mouse lymphoma cells with or without the S9 mix in the in vitro comet assay. No statistically significant differences in the incidence of chromosomal aberrations following HS-1793 treatment was observed on Chinese hamster lung cells exposed with or without the S9 mix. These results provide additional evidence that HS-1793 is non-genotoxic at the dose tested in three standard tests and further supports the generally recognized as safe determination of HS-1793 during early drug development.

• Korean Journal of Radiology
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• 제22권7호
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• pp.1034-1043
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• 2021

Objective: The purpose of this meta-analysis was to investigate the pooled agreements of the coronary artery calcium (CAC) severities assessed by electrocardiogram (ECG)-gated and non-ECG-gated CT and evaluate the impact of the scan parameters. Materials and Methods: PubMed, EMBASE, and the Cochrane library were systematically searched. A modified Quality Assessment of Diagnostic Accuracy Studies-2 tool was used to evaluate the quality of the studies. Meta-analytic methods were utilized to determine the pooled weighted bias, limits of agreement (LOA), and the correlation coefficient of the CAC scores or the weighted kappa for the categorization of the CAC severities detected by the two modalities. The heterogeneity among the studies was also assessed. Subgroup analyses were performed based on factors that could affect the measurement of the CAC score and severity: slice thickness, reconstruction kernel, and radiation dose for non-ECG-gated CT. Results: A total of 4000 patients from 16 studies were included. The pooled bias was 62.60, 95% LOA were -36.19 to 161.40, and the pooled correlation coefficient was 0.94 (95% confidence interval [CI] = 0.89-0.97) for the CAC score. The pooled weighted kappa of the CAC severity was 0.85 (95% CI = 0.79-0.91). Heterogeneity was observed in the studies (I² > 50%, p < 0.1). In the subgroup analysis, the agreement between the CAC categorizations was better when the two CT examinations had reconstructions based on the same slice thickness and kernel. Conclusion: The pooled agreement of the CAC severities assessed by the ECG-gated and non-ECG-gated CT was excellent; however, it was significantly affected by scan parameters, such as slice thickness and the reconstruction kernel.

• 재활간호학회지
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• 제19권1호
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• pp.20-29
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• 2016

Purpose: The purpose of this study was to develop Situation, Background, Assessment, Recommendations(SBAR) program and to test the effects of the program on communication clarity, clinical competence, and self-efficacy for clinical nurses in cancer hospitals. Methods: This study applied a nonequivalent control group non-synchronized design. There were 28 participants in the intervention group and 27 in the control group. SBAR program consisted of 4 parts and applied for 6 weeks in the intervention group. Data were analyzed with ${\chi}^2$ test, Fisher's exact test, t-test and ANCOVA using the SPSS program. Results: Communication clarity, clinical competence and self efficacy were significantly increased in the intervention group compared to those in the control group. Conclusion: These results suggest that SBAR program may improve communication clarity, clinical competence and self-efficacy for clinical nurses in cancer hospitals. Therefore, it is required to actively take advantage of this program to improve communication clarity among medical staffs, clinical competence, and self-efficacy in clinical nursing practices.

• Korean Journal of Radiology
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• 제24권12호
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• pp.1200-1220
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• 2023

Dilated cardiomyopathy (DCM) is one of the most common types of non-ischemic cardiomyopathy. DCM is characterized by left ventricle (LV) dilatation and systolic dysfunction without coronary artery disease or abnormal loading conditions. DCM is not a single disease entity and has a complex historical background of revisions and updates to its definition because of its diverse etiology and clinical manifestations. In cases of LV dilatation and dysfunction, conditions with phenotypic overlap should be excluded before establishing a DCM diagnosis. The differential diagnoses of DCM include ischemic cardiomyopathy, valvular heart disease, burned-out hypertrophic cardiomyopathy, arrhythmogenic cardiomyopathy, and non-compaction. Cardiac magnetic resonance (CMR) imaging is helpful for evaluating DCM because it provides precise measurements of cardiac size, function, mass, and tissue characterization. Comprehensive analyses using various sequences, including cine imaging, late gadolinium enhancement imaging, and T1 and T2 mapping, may help establish differential diagnoses, etiological work-up, disease stratification, prognostic determination, and follow-up procedures in patients with DCM phenotypes. This article aimed to review the utilities and limitations of CMR in the diagnosis and assessment of DCM.