• Steel and Composite Structures
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• v.20 no.4
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• pp.869-887
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• 2016

The socket-spigot template supporting system is widely used in engineering applications in China. As a newer type of support structure, there has been growing research interest in its bearing capacity. In this paper, four vertical bearing capacity tests were carried out on the basic mechanical unit frame of a socket-spigot template supporting system. The first goal was to explore the influence of the node semi-rigid degree and the longitudinal spacing of the upright tube on the vertical bearing capacity. The second objective was to analyze the displacement trend and the failure mode during the loading process. This paper presents numerical analysis of the vertical bearing capacity of the unit frames using the finite element software ANSYS. It revealed the relationship between the node semi-rigid degree and the vertical bearing capacity, that the two-linear reinforcement model of elastic-plastic material can be used to analyze the socket-spigot template supporting system, and, through node entity model analysis, that the load transfer direction greatly influences the node bearing area. Finally, this paper indicates the results of on-site application performance experiments, shows that the supporting system has adequate bearing capacity and stability, and comments on the common work performance of a socket and fastener scaffold.

• Journal of the Korean School Mathematics Society
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• v.17 no.1
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• pp.93-108
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• 2014

In this paper we carried out a survey targeting 185 elementary, middle and high school mathematics teachers to identify their conception, satisfaction, requirements of after-school mathematics education. The survey results show that we need to develop newer programs, reduce teachers' task, build a more effective system for supporting and researching after-school mathematics education, and so on. Using these survey results we understand the facts of existing after-school mathematics education and provide preliminary data for discussing how to invigorate and advance the after-school mathematics education.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.1
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• pp.1-8
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• 2006

Addiction to illicit drugs is one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems is not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis. Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In audition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further.

• Korean Journal of Biological Psychiatry
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• v.6 no.2
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• pp.259-263
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• 1999

Nefazodone, a newer antidepressant is a phenylpiperazine derivative that inhibits the reuptake of both norepinephrine and serotonin, and antagonizes $5-HT_{2A}$ and ${\alpha}_1$ adrenergic receptors. Compared with SSRIs, nefazodone caused the fewer activating symptoms, adverse gastrointestinal effects(nausea, diarrhea, anorexia) and adverse effects of sexual function, but is associated with the more dizziness, dry mouth, constipation, visual disturbances and confusion. We report on 4 cases of visual disturbances and hallucinations in patients taking nefazodone. It is not certain what mechanisms mediated these side effects, but three mechanisms are possible. 1) Nefazodone, as a 5-HT2 antagonist, might induce visual disturbances. 2) mCPP, metabolite of nefazodone might contribute to the hallucination through action on 5-HT receptor. 3) Dopaminergic enhancing activity of nefazodone might cause hallucination. These case report raises the possibility that dose-related perceptual disturbances may exist with nefazodone. The fact emphasizes the need to pay close attention to all possible drug interactions, particularly in patients treated with multiple psychoactive agents, older patients, and patients with decreased hepatic function.

• Korean Journal of Biological Psychiatry
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• v.4 no.1
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• pp.132-135
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• 1997

Current treatment strategies for levodopa-induced psychosis in advanced Parkinson's disease have had limited success. Reduction or discontinuation of levodopa and coadministration with dopamine-blocking neuroleptics may attenuate the psychotic symptoms, but these strategies are associated with worsening of parkinsonian symptoms. Administration of 5-HT3 receptor antagonist ; ondansetron, a newer strategy to attenuate psychosis of Parkinson'disease without motor deterioration was introduced. A 41-year-old young-onset male, who was diagnosed as Parkinson's disease 7 years ago, was treated with levodopa therapy, and had levodopa-induced psychosis(delusion, hallucination, paranoid, insomnia). After trial of ondansetron, he showed improvement in the Brief Psychiatric Rating Scale(from 21 points to 9 points) in spite of increasing the dosage of levodopa. With ondansetron, we could increase the dosage of levodopa without psychotic complications(esp, hallucination), and he showed improvement in the motor fluctuation.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.663-663
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• 2002

The National Oceanographic Research Institute of KOREA started to survey for the basic data necessary to territorial sea and EEZ identification and marine development with Multi-Beam Echo Sounder(L3 SeaBeam 2112) since 1996. The Multi-Beam surveys has provided a very new and precise way of describing the morphology and nature of the underwater seabed. Multi-Beam Echo Sounder systems employ sound waves propagating at angles which vary from vertical to nearly horizontal. The locations on the bottom where echoes are generated cover a swath whose port to starboard width may be equal to many times the water depth. Newer Multi-beam bathymetric sonars provide both a beam by beam depth and backscatter amplitude of the bottom. But The backscattered amplitude didn't use for identification of bottom properties because backscatter amplitude effects by the many environmental variables of underwater and seabed. We investigates the utilization of geo-referenced backscatter amplitude and analysis of relationship between The Backscattered Amplitude and Sidescan Sonar imagery from Sea Beam 2112. For the backscattered amplitude imagery mainly represents the properties of sediment, we computed the beam geometry, time-varied amplifier gain, and mainly incidence angle to the topography using bathymetric model at each ping. In this paper, those issues are illustrated, and the angular independent imagery based on swath topographic model is described.

• Journal of Life Science
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• v.5 no.3
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• pp.145-150
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• 1995

Alcoholic liver disease is defined by the development of three types of liver damage following chronic heavy alcohol consumption, namely, alcoholic fatty liver, alcoholic hepatitis, and alcoholic cirrhosis, The clinical features and laboratory tests often do not distinguish among these types of liver injuries. In addition, a considerable number of the patients who have clinical and laboratory features compatible with alcoholic liver disease are diagnosed on liver biopsy to have chronic viral hepatitis or other lesion. Because of these factors, liver biopsy is frequently needed to arrive a definite diagnosis of the disease, its activity, and its chronicity. Fatty liver is usually a benign and reverible condition that disappears on abstinence from alcohol. However, alcoholic hepatitis is usually regarded as a precursor of cirrhosis. The principle factors in the development of alcoholic hepatitis and cirrhosis are the quantity and length of ingestion of alcohol. women are much more susceptible than men to hepatic injuries. Since only 10 - 20% of alcoholics develop cirrhosis, however, it is conceivable that other factors, either genetic, environmental, or nutritional may contribute in the genesis of liver injuries. The most important factor in the treatment of alcoholic liver disease is prolonzed abstinence from alcohol, since abstinence by itself improves clinical status and survival, Nutritional support in patients with nutritional deficiency, and specific drug therapies such as corticosteroid or anabolic steroids for hospitaliged patients with severe alcoholic hepatitis also play an important role in devreasing morbidity and improving survival. Liver transplantation is a newer treatment modality in the patients with advanced cirrhosis, not responsible to medical treatment.

• Journal of the Korean earth science society
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• v.26 no.2
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• pp.129-136
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• 2005

Continued observation of ARGO floats for years(about 4 years) makes the conductivity sensor more vulnerable to fouling by marine life and associated drift in salinity measurements. In this paper, we address this issue by making use of floats deployed in different years. Floats deployed in the East Sea and the Indian Ocean are examined to find out float-to-float match-ups in such a way that an older float pops up simultaneously with a newer deployment (with tolerable space-time difference). A time difference of less than five days and space difference of less than 100km are considered for the match-up data sets. For analysis of the salinity drift under the stable water mass, observations of the floats from deepest water masses have been used. From the cross-check of ARGO floats in the East Sea and the Indian Ocean, it is found that there is a systematic drift in the older float compared to later deployments. All drift results, consistently show negative bias indicating the typical nature of drift from fouled sensors. However, the drift is much less than 0.01, the specified accuracy of ARGO program.

• Journal of the Korean Society of Fashion and Beauty
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• v.1 no.1 s.1
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• pp.79-94
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• 2003

The purpose of this study was to discuss how make-up materials were used for the design techniques of special make-up that is part of impersonation, what kinds of materials were applied to special make-up design and how they were utilized, in a bid to find out more materials available for each of diverse design techniques in pursuit of better make-up design. The most widely used materials were divided into transformational and supplementary types, and the focus of this study was placed on two different design techniques. One put transformational materials to use, and the other utilized supplementary materials that also could serve as alternative and effect materials. Unlike general make-up that pursues beauty, special make-up focuses on realistic effect, and it cannot make any progress without newer, diverse materials which are increasingly gaining in importance. Although special make-up designing is a skilled technique that requires systematic knowledge of theories, proper materials and repeated practice, there is no absolute standard for it, since it is a product of imagination and depends on delicate hand skills and its effect hinges on individual viewer's visual perspective. In the future, more comprehensive and broader-scale experiments are called for to tackle this problem.

• Clinical and Experimental Pediatrics
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• v.51 no.10
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• pp.1031-1037
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• 2008

Macrolide antimicrobial agents including erythromycin, roxithromycin, clarithromycin, and azithromycin are commonly used in the treatment of respiratory tract infections in children. Newer macrolides that have structural modifications of older drug erythromycin show improved change in the spectrum of activity, dosing, and administration. However, recent studies reported that increasing use of macrolide antibiotics is the main force driving the development of macrolide resistance in streptococci. In particular, azithromycin use is more likely to select for macrolide resistance with Streptococcus pneumoniae than is clarithromycin use, a possible reflection of its much longer half life. Recently, erythromycin resistance rates of S. pneumoniae and Streptococcus pyogenes are rapidly increasing in Korea. Two main mechanisms of acquired macrolide resistance have been described, altered binding site on the bacterial ribosome encoded by the ermB gene and active macrolide efflux pump encoded by the mef gene. Relationship between the susceptibility of S. pneumoniae and the response to macrolides has been shown in studies of acute otitis media, but less clear in cases of pneumonia. This article reviews the spectrum of activity, pharmacokinetic properties, mechanisms of action and resistance, and clinical implication of resistance on the treatment of respiratory tract infections in children.