• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1998.06a
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• pp.573-578
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• 1998

In this paper, we propose a new technique of codification. The purpose of this method is to take in consideration the natural language nuances and the fuzziness that characterizes the human reasoning. So, we warranted a means of more flexible encoding that translates as well the linguistic descriptions. Its principle is simple and intuitive. It consists simply in replacing in ambiguous cases, a unique number by an interval. The introduction of the new codification necessitates the elaboration of metric or similarity in order to compare two intervals. This comparison must take in consideration the difference of their size, the remoteness of their center and the width of their intersection. In consequence, we defined three new fuzzy concepts : "fuzzy inclusion degree", "fuzzy resemblance degree," and " fuzzy curve".

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9355-9360
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• 2014

Background: Oral squamous cell carcinoma (OSCC) remains as one of the most difficult malignancies to control because of its high propensity for local invasion and cervical lymph node dissemination. In this study, we evaluate the efficacy of our novel pH and temperature sensitive doxorubicin-methotrexate-loaded nanoparticles (DOX-MTX NP) in affecting HER2 expression profile in OSCC model in rat. Results: DOX-MTX- nanoparticle complexes caused significant decrease in mRNA level of HER2 compared to untreated cancers (p<0.05) and this finding was more pronounced with the IV mode (p<0.000). Surprisingly, HER2 mRNA was not affected in DOX treated as compared to the control group (p>0.05). On the other hand, in the DOX-MTX NP treated group, fewer tumors characterized with advanced stage and decreased HER2 paralleled improved clinical outcome (P<0.05). Moreover, the effectiveness of the oral route in the group treated with nanodrug accounted for the enhanced bioavailability of nanoparticulated DOX-MTX compared to free DOX. Furthermore, there was no significant difference in mRNA level of HER2 (p>0.05). Conclusions: Influence of HER2 gene expression is a new feature and mechanism of action observed only in dual action DOX-MTX-NPs treated groups. Down-regulation of HER2 mRNA as a promising marker and prognosticator of OSCC adds to the cytotoxic benefits of DOX in its new formulation. Both oral and IV application of this nanodrug could be used, with no preferences in term of their safety or toxicity. As HER2 is expressed abundantly by a wide spectrum of tumors, i DOX-MTX NPs may be useful for a wide-spectrum of lesions. However, molecular mechanisms underlying HER2 down regulation induced by DOX-MTX NPs remain to be addressed.

• Journal of Digital Convergence
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• v.13 no.2
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• pp.35-42
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• 2015

As the value of Bigdata has been recognized importantly, public agencies including the government, private sector, etc. began to have an interest in Big Data. As there are sources of various data, and a variety of planning and analysis methods based on these sources has emerged, It is true that Bigdata will become a tool for creation of the new high qualitied information and decision making based on new insights. The purpose of this study is to find an alternative to the subway congestion problem that is not improved even though the various measures. In this study, we tried to explore approaches for ways to improve the congestion of the Seoul Subway using Seoul Metropolitan public data. Lastly, this study derived a policy alternative to establish new bus route that runs around the metro station that have a high level of congestion.

• The KIPS Transactions:PartC
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• v.19C no.3
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• pp.191-208
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• 2012

Proxy Mobile IPv6 (PMIPv6) is designed to provide network-based mobility management support to an MN without any involvement of the MN in the mobility related signalling, hence, the proxy mobility entity performs all related signalling on behalf of the MN. The new principal functional entities of PMIPv6 are the local mobility anchor (LMA) and the mobile access gateway (MAG). In PMIPv6, all the data traffic sent from the MN gets routed to the LMA through a tunnel between the LMA and the MAG, but it still has the single point of failure (SPOF) and bottleneck state of traffic. To solve these problems, various approaches directed towards PMIPv6 performance improvements such as route optimization proposed. But these approaches add additional signalling to support MN's mobility, which incurs extra network overhead and still has difficult to apply to multiple-LMA networks. In this paper, we propose a improved route optimization in PMIPv6-based multiple-LMA networks. All LMA connected to the proxy internetworking gateway (PIG), which performs inter-domain distributed mobility control. And, each MAG keeps the information of all LMA in PMIPv6 domain, so it is possible to perform fast route optimization. Therefore, it supports route optimization without any additional signalling because the LMA receives the state information of route optimization from PIG.

• Journal of the Korean Society of Marine Environment & Safety
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• v.24 no.1
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• pp.36-42
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• 2018

This paper considers the Marine Traffic Risk Assessment for fixed and moving targets, which threaten officers during a voyage. The Collision Risk Assessment Formula was calculated based on a dynamic ship domain considering the length, speed and maneuvering capability of a vessel. In particular, the Navigation Risk Assessment Model that is used to quantitatively index the effect of a ship's size, speed, etc. has been reviewed and improved using a hybrid combination of a vessel's dynamic area and the Collision Risk Assessment Formula. Accordingly, a new type of Marine Traffic Risk Assessment Model has been suggested giving consideration to the Speed Length Ratio, which was not sufficiently reflected in the existing Risk Assessment Model. The larger the Speed Length Ratio (dimensionless speed), the higher the CJ value. That is, the CJ value is presented well by the Speed Length Ratio. When the Speed Length Ratio is large, states ranging from [Caution], [Warning], [Dangerous] or [Very Dangerous] are presented from a greater distance than when the Speed Length Ratio is small. The results of this study, can be used for route and port development, including dangerous route avoidance, optimum route planning, breakwater width, bridge span, etc. as well as the development of costal navigation safety charts. This research is also applicable for the selection of optimum ship routing and the prevention of collisions for smart ships such as autonomous vessels.

• Journal of Korean Society of Transportation
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• v.26 no.5
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• pp.81-90
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• 2008

Bus passengers need some time to adapt to the changed bus route or free bus transfer system which is part of the public transportation system restructuring plan. This research is focused on the characteristics of monthly patterns of bus passengers. The period of stabilization of bus passenger demand after the rearrangement of bus route system by a time series were analysed. In order to look into the characteristics of bus passenger demand by month, data on the number of monthly bus passengers of recent five years in metropolitan cities across the nation was collected. Kendall's coefficient of concordance is used to test whether the cities showed concordance with respect to the number of monthly bus passengers during a period of five years. The study collected and performed a time series analysis of data on the number of monthly bus passengers during the past ten years in Daegu metropolitan area which carried out a new bus route plan in February 2006. The number of monthly bus passengers in 2006 was estimated using the time series analysis. The city of Daegu found that after six months the estimated and actual values displayed a similar pattern. This result can be applied to other cities in estimating the passenger demands in the future.

• Spatial Information Research
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• v.22 no.5
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• pp.19-26
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• 2014

International attention on the Northern Sea Route has been increased as the decreased sea-ice extents in Northern Sea raise the possibility to develop new sea routes and natural resources. However, to protect ships' safety and pristine environments in polar waters, International Maritime Organization(IMO) has been developing the Polar Code to regulate polar shipping. The marine navigation supporting system is essential for ships traveling long distance in the Northern Sea as they are affected by ocean weather and sea-ice. Therefore, to cope with the IMO Polar Code, this research proposes the functional requirements to develop the marine navigation supporting system for the Northern Sea Route. The functional requirements derived from the IMO Polar code consist of arctic voyage risk map, arctic voyage planning and MSI(Marine Safety Information) methods, based on which the navigation supporting system is able to provide dynamic and safe-economical sea route service using the sea-ice observation and prediction technologies. Also, a requirement of the system application is derived to apply the marine navigation supporting system for authorizing ships operating in the Northern Sea. To reflect the proposed system in the Polar Code, continual international exchange and policy proposals are necessary along with the development of sea-ice observation and prediction technologies.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.12
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• pp.17-23
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• 2010

In the mobile cloud computing, the mobile node should request and receive the services while being connected. In PMIPv6, all packets sent by mobile nodes or correspondent nodes are transferred through the local mobility anchor. This unnecessary detour still results in high delivery latency and significant processing cost. Several PMIPv6 route optimization schemes have been proposed to solve this issue. However, they also suffer from the high signaling costs and handover latency when determining the optimized path. We propose the route optimization handover scheme which adopts the prediction algorithm in PFMIPv6. In the proposed scheme, the new mobile access gateway establishes the bi-directional tunnel with the correspondent node's MAG using the context message when the mobile node's handover is imminent. This tunnel may eliminate the need of separate route optimization procedure. Hence, the proposed scheme can reduce the signaling cost than other conventional schemes do. Analytical performance evaluation is preformed to show the effectiveness of the proposed scheme. The result shows that our scheme is more effective than other schemes.

• Spatial Information Research
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• v.19 no.4
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• pp.11-20
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• 2011

In accordance with low carbon and green growth paradigm, a subway is one of major public transit systems for resolving traffic congestion and decreasing traffic accidents. In addition, as subway networks expand, passengers' travel pattern in the subway network change and consequently affect the urban structure. Generally, new subway route has been planned and developed, mainly considering a travel demand forecast. However, it is desired to conduct an empirical analysis on the forecast model regarding change of travel accessibility and passenger demand pattern according to new subway line. Therefore, in this paper, an alternative method, developed based upon a spatial syntax model, is proposed for evaluating new subway route in terms of passenger's mobility and network accessibility. In a case study, we constructed subway network data, mainly targeting the no 9 subway line opened in 2009. With an axial-map analysis, we calculated spatial characteristics to describe topological movement interface. We then analyzed actual modal shift and change on demand of passengers through the number of subway passenger between subway stations and the number of passenger according to comparative bus line from Smart Card to validate suggested methods. Results show that the proposed method provides quantitative means of visualizing passenger flow in subway route planning and of analyzing the time-space characteristics of network. Also, it is expected that the proposed method can be utilized for predicting a passengers' pattern and its impact on public transportation.

• Korean Journal of Heritage: History & Science
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• v.45 no.3
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• pp.174-193
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• 2012

This study focused on distribution ratio of stone properties based on material characteristic analysis, provenance presumption and transportation route interpretation of the Sungnyemun stone block foundation. The stone block foundation is composed of pinkish granite (56.0%), reddish granite (4.5%) and leucocratic granite (26.2%) of original stones and pinkish granite of new stones(13.3%). The rock-forming minerals for granites are consisted mainly of quartz, alkali-feldspar, plagioclase and biotite, and are similar geochemical evolution trend of major, rare earth, compatible and incompatible elements. Therefore, it is clear that the rocks are genetically same origin. As a result of magnetic susceptibility measurement, the pinkish and reddish granite of original stones and pinkish granite of new stones showed normal distribution around about 4.00(${\times}10^{-3}SI\;unit$). But the leucocratic granite of original stones were confirmed ilmenite series under about 1.00(${\times}10^{-3}SI\;unit$). As a result of provenance interpretation and transportation route analysis based on the petrological results, the provenance of pinkish granite and reddish granite of original stones are presumed the north slope in Namsan mountain and Naksan mountain. Also, the leucocratic granite of original stones and the pinkish granite of new stones are strongly possible furnished from the south and north slope in Namsan mountain and Naksan mountain, respectively.