• Journal of Life Science
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• v.26 no.2
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• pp.265-274
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• 2016

Toxin-antitoxin (TA) systems are ubiquitous genetic modules that are evolutionally conserved in bacteria and archaea. TA systems composed of an intracellular toxin and its antidote (antitoxin) are currently classified into five types. Commonly, activation of toxins under stress conditions inhibits diverse cellular processes and consequently induces cell death or reversible growth inhibition. These effects of toxins play various physiological roles in such as regulation of gene expression, growth control (stress response), programmed cell arrest, persister cells, programmed cell death, phage protection, stabilization of mobile genetic elements or postsegregational killing of plasmid-free cells. Accordingly, bacterial TA systems are commonly considered as stress-responsive genetic modules. However, molecule screening for activation of toxin in TA system is available as development of antimicrobial agents. In addition, cytotoxic effect induced by toxin is used as effective cloning method with antitoxic effect of antitoxin; consequently cells containing cloning vector inserted a target gene can survive and false-positive transformants are removed. Also, TA system is applicable to efficient single protein production in biotechnology industry because toxins that are site-specific ribonuclease inhibit protein synthesis except for target protein. Furthermore, some TA systems that induce apoptosis in eukaryotic cells such as cancer cells or virus-infected cells would have a wide range of applications in eukaryotes, and it will lead to new ways of treating human disease. In this review, we summarize the current knowledge on bacterial TA systems and their applications.

• Journal of the Korean Chemical Society
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• v.65 no.2
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• pp.133-144
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• 2021

Science teachers in elementary schools and secondary schools recognize the necessity of character education, feeling difficulties such as evaluation methods, mood of competition, extra work and lack of time according to previous research, which were based on answers from science teachers not experiencing character education. As a rare study of teacher experiencing, previous researches didn't fully address the problems and suggestions about adopting character education in science classrooms. This study is about teacher practice of character education on site with the CoProC (Collaborative Problem-Solving for Character Competence) program in science classes with which other previous studies shed new light. Five teachers, adapting the CoProC program in their science classes, participated in two interviews, sharing their student achievement in character education. Results showed that student achievement was high when their teacher had experienced the training program, development, and classes of CoProC rather than their normal teaching career. Teacher recognition on the aims of CoProC influenced difficulties, evaluation, and feedback.

• Journal of Korean Society of Forest Science
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• v.110 no.4
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• pp.479-495
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• 2021

To improve on the efficient management of forest resources, it is necessary to create a forest soil map, which represents a comprehensive database of forest lands. Although a 1:25,000 scale forest site map has been used in Korea, the need for a large-scale forest soil map with high precision and information on forest lands that is specialized for individual purposes has been identified. Moreover, to keep pace with the advancement in forest management and transition to a digital society, it is essential to develop a method for constructing new forest soil maps that can diversify its use. Therefore, this paper presented a developmental process and used a 1:5,000 scale forest soil map to propose future directions. National maps showing the soil type, depth, and texture were produced based on the survey and analysis of forest soils, followed by the Forest Land Soil Map (1:5,000) Production Standard Manual. Alternatively, forest soil map data were the basis on which various other maps that can be used to prevent and predict forest disasters and evaluate environmental capacities were developed. Accordingly, ways to provide appropriate information to achieve the national forest plan, secure forestry big data, and accomplish sustainable forest management that corresponds to the national development plan are proposed based on results from the current study.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.16-22
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• 2019

Off-line programming and robot calibration through simulation are essential when setting up a robot in a robot automation production line. In this study, we developed a new robot calibration method to match the CAD data of the production line with the measurement data on the site using 3D scanner. The proposed method calibrates the robot using 3D point cloud data through Iterative Closest Point algorithm. Registration is performed in three steps. First, vertices connected by three planes are extracted from CAD data as feature points for registration. Three planes are reconstructed from the scan point data located around the extracted feature points to generate corresponding feature points. Finally, the transformation matrix is calculated by minimizing the distance between the feature points extracted through the ICP algorithm. As a result of applying the software to the automobile welding robot installation, the proposed method can calibrate the required accuracy to within 1.5mm and effectively shorten the set-up time, which took 5 hours per robot unit, to within 40 minutes. By using the developed system, it is possible to shorten the OLP working time of the car body assembly line, shorten the precision teaching time of the robot, improve the quality of the produced product and minimize the defect rate.

• Korean Journal of Heritage: History & Science
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• v.51 no.2
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• pp.154-169
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• 2018

In modern society, cultural heritage has played a role in constituting national identity. The Cultural Heritage Education Project started in the 2000s by the Cultural Heritage Administration was also aware of the issue of sustainable development and cultural diversity as major cultural issues at the time. However, the main purpose of previous cultural heritage education was to foster national identity. The Cultural Heritage Administration has executed cultural heritage education programs since 2006. The education program of the cultural heritage teacher visiting the school, the project to designate a cultural heritage school, and an education program to experience cultural heritage at an archaeological site were carried out. In the 2010s, the theme of cultural rights and enjoyment of cultural heritage in life was raised as an important issue. Cultural heritage education had to accept the 'new meaning of cultural heritage', 'cultural rights', and 'learnercentered education'. In this context, the local cultural heritage education project started. The region is a space where various identities are reconstructed. However, local cultural heritage education itself cannot realize cultural heritage enjoyment in life. Therefore, it is necessary to seek cultural heritage in life through the various efforts of local cultural heritage education.

• Korean Journal of Heritage: History & Science
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• v.35
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• pp.284-303
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• 2002

The purpose of this research paper is to examine, from an ethnological viewpoint, the traditional practice of using sacrificial game and domestic livestock as is often seen at communal rites in Korea. This paper also examine how the more convenient use of livestock sacrifice developed from that in which wild game were once offered, and how this change in the type of animals used affected the significance of the sacrifice. It also looks at how the use of animal sacrifice for ceremonies eventually influenced the practice of meat consumption on the part of the participants in their daily life, and how it contributed to the eventual establishment and development of livestock breeding for the purpose of meat consumption. The practice of catching wild game in the mountains for sacrificial purposes eventually gave way to the use of pasturage cattle, but it should be understood that these domesticated livestock were raised primarily for ceremonial rather than meat consumption purpose. When used for sacrifice, these cattle were not castrated, as is normally done when they are slaughtered for meat consumption, but it should not be assumed that this was done for purposes of simplification. In addition, not only rice farmers but also when enterpreneurs set up a new enterprise, animal sacrifice was viewed not only as a form of on-site purification of evil, but also served the dual purpose of enhancing their business through the traditional custom of serving meat to those invited guests in attendance. In the large-scale village communal rite of Hwaghae Province located in the northwestern part of Korea, animal sacrifice was carried out in the ritual for the Mountain God in a highly dramatic style, and suggests that it originated with the agrarian rites of the "fire-field" farmers of East Asia, which were utilized to foretell whether the coming year would be one of abundance or famine, and to the royal ceremony held on the 3rd day of the 3rd month of the lunar calendar, as well as that held for the God of the Mountains and Streams. The dramatic-style hunting rite, included in the large-scale communal ritual of Hwanghae Province mentioned previously, as well as in the Ritual of the Cow from Pyungsan, also located in Hwanghae Province, in which wild game were used as sacrifice, is significant in that it points up the changes that have occurred in ceremonial animal sacrifice. However, more research on ritualistic animal sacrifice is still called for in rites for good farming, fishing, and the variety of others that are held throughout Korea.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.24 no.6
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• pp.49-65
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• 2021

Although the Environmental Impact Assessment (EIA) is continuously being advanced, the number of environmental disputes regarding it is still on the rise. In order to supplement this, it is necessary to analyze the accumulated complaint cases. In this study, through the analysis of complaint cases, it is possible to identify matters that need to be improved in the existing EIA stages as well as various damages and conflicts that were not previously considered or predicted. In the process, we dervied 'complaint-based data demands' that should be additionally examined to improve the EIA. To this end, a total of 348 news articles were collected by searching with combinations of 'environmental impact assessment' and a keyword for each of the six assessment groups. As a result of analysis of collected data, a total of 54 complaint-based data demands were suggested. Among those were 15 items including 'impact of changes in seawater flow on water quality' in the category of water environment; 13 items including 'area of green buffer zone' in atmospheric environment; 10 items including 'impact of soundproof wall on wind corridor' in living environment; 8 items including 'expected number of users' in socioeconomic environment, 4 items including 'feasibility assessment of development site in terms of environmental and ecological aspects' in natural ecological environment; and 4 items including 'prediction of sediment runoff and damaged areas according to the increase in intensity and frequency of torrential rain' in land environment. In future research, more systematic complaint collection and analysis as well as specific provision methods regarding stages, subjects, and forms of use should be sought to apply the derived data demands in the actual EIA process. It is expected that this study can serve to advance the prediction and assessment of EIA in the future and to minimize environmental impact as well as social conflict in advance.

• Korean Journal of Agricultural and Forest Meteorology
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• v.23 no.4
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• pp.268-279
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• 2021

The geospatial schemes based on topo-climatology have been developed to produce digital climate maps at a site-specific scale. Their development processes are reviewed here to derive the needs for new schemes in the future. Agricultural and forestry villages in Korea are characterized by complexity and diversity in topography, which results in considerably large spatial variations in weather and climate over a small area. Hence, the data collected at a mesoscale through the Automated Synoptic Observing System (ASOS) operated by the Korea Meteorological Administration (KMA) are of limited use. The geospatial schemes have been developed to estimate climate conditions at a local scale, e.g., 30 m, lowering the barriers to deal with the processes associated with production in agricultural and forestry industries. Rapid enhancement of computing technologies allows for near real-time production of climate information at a high-resolution even in small catchment areas and the application to future climate change scenarios. Recent establishment of the early warning service for agricultural weather disasters can provide growth progress and disaster forecasts for cultivated crops on a farm basis. The early warning system is being expanded worldwide, requiring further advancement in geospatial schemes and digital climate mapping.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.520-533
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• 2021

It is necessary to increase the blasting efficiency in order to minimize the economic loss caused when the excavation cross section is reduced due to the stability problem of underground mining development, and for this, a new blasting design is proposed. In this study, the blasting efficiency of the general design in the field, the suggestion designI, which added two columns to production blasting, and the suggestion design II, which added one column to create asymmetry, is compared. Advance rate and fragmentation were selected as the evaluation index of the blasting efficiency. In the case of advance rate, compared to the normal, the suggestionI improved by 6.07% and the suggestionII improved by 4.65%. In the case of fragmentation, based on P80, compared to the normal, the suggestionI reduced about 58% and the suggestionII was about 47%. Accoording to the evaluation index, the suggestion designI shows better blasting efficiency than the suggestion designII. But considering the additional work time and cost required for the suggestion designI due to the insignificant difference in the evaluation index results, the asymmetry V-cut, the suggestion designII, is judged to be a more suitable blasting design for the site.

• Korean Journal of Construction Engineering and Management
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• v.23 no.4
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• pp.15-25
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• 2022

As the incidence and mortality of serious disasters in the construction industry are the highest, various efforts are being made in Korea to reduce them. Among them, risk assessment is used as data for disaster reduction measures and evaluation of risk factors at the construction stage. However, the existing risk assessment involves the subjectivity of the performer and is vulnerable to the domestic construction site. This study established a DB classification system for risk assessment with the aim of early identification and pre-removal of risks by quantitatively deriving risk factors using BIM in the risk assessment field and presents a methodology for risk assessment using BIM. Through this, prior removal of risks increases the safety of construction workers and reduces additional costs in the field of safety management. In addition, since it can be applied to new construction methods, it improves the understanding of project participants and becomes a tool for communication. This study proposes a framework for deriving quantitative risks based on BIM, and will be used as a base technology in the field of risk assessment using BIM in the future.