1 |
Germain, E., Castro-Roa, D., Zenkin, N. and Gerdes, K. 2013. Molecular mechanism of bacterial persistence by HipA. Mol. Cell 52, 248-254.
DOI
|
2 |
Goeders, N. and Van Melderen, L. 2014. Toxin-antitoxin systems as multilevel interaction systems. Toxins (Basel) 6, 304-324.
DOI
|
3 |
Hallez, R., Geeraerts, D., Sterckx, Y., Mine, N., Loris, R. and Van Melderen, L. 2010. New toxins homologous to ParE belonging to three-component toxin-antitoxin systems in Escherichia coli O157:H7. Mol. Microbiol. 76, 719-732.
DOI
|
4 |
Miki, T., Park, J. A., Nagao, K., Murayama, N. and Horiuchi, T. 1992. Control of segregation of chromosomal DNA by sex factor F in Escherichia coli. Mutants of DNA gyrase subunit A suppress letD (ccdB) product growth inhibition. J. Mol. Biol. 225, 39-52.
DOI
|
5 |
Munoz-Gomez, A. J., Lemonnier, M., Santos-Sierra, S., Berzal-Herranz, A. and Diaz-Orejas, R. 2005. RNase/anti-RNase activities of the bacterial parD toxin-antitoxin system. J. Bacteriol. 187, 3151-3157.
DOI
|
6 |
Jaffe, A., Ogura, T. and Hiraga, S. 1985. Effects of the ccd function of the F plasmid on bacterial growth. J. Bacteriol. 163, 841-849.
|
7 |
Jiang, Y., Pogliano, J., Helinski, D. R. and Konieczny, I. 2002. ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase. Mol. Microbiol. 44, 971-979.
DOI
|
8 |
Jones, L. J., Carballido-Lopez, R. and Errington, J. 2001. Control of cell shape in bacteria: helical, actin-like filaments in Bacillus subtilis. Cell 104, 913-922.
DOI
|
9 |
Jorgensen, M. G., Pandey, D. P., Jaskolska, M. and Gerdes, K. 2009. HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea. J. Bacteriol. 191, 1191-1199.
DOI
|
10 |
Kawano, M., Aravind, L. and Storz, G. 2007. An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin. Mol. Microbiol. 64, 738-754.
DOI
|
11 |
Lee, M. W., Rogers, E. E. and Stenger, D. C. 2012. Xylella fastidiosa plasmid-encoded PemK toxin is an endoribonuclease. Phytopathology 102, 32-40.
DOI
|
12 |
Leplae, R., Geeraerts, D., Hallez, R., Guglielmini, J., Dreze, P. and Van Melderen, L. 2011. Diversity of bacterial type II toxin-antitoxin systems: a comprehensive search and functional analysis of novel families. Nucleic Acids Res. 39, 5513-5525.
DOI
|
13 |
Park, J. H., Yamaguchi, Y. and Inouye, M. 2012. Intramolecular regulation of the sequence-specific mRNA interferase activity of MazF fused to a MazE fragment with a linker cleavable by specific proteases. Appl. Environ. Microbiol. 78, 3794-3799.
DOI
|
14 |
Park, S. J., Son, W. S. and Lee, B. J. 2013. Structural overview of toxin-antitoxin systems in infectious bacteria: a target for developing antimicrobial agents. Biochim. Biophys. Acta 1834, 1155-1167.
DOI
|
15 |
Mutschler, H. and Meinhart, A. 2011. Epsilon/zeta systems: their role in resistance, virulence, and their potential for antibiotic development. J. Mol. Med. (Berl) 89, 1183-1194.
DOI
|
16 |
Lopes, A. P., Lopes, L. M., Fraga, T. R., Chura-Chambi, R. M., Sanson, A. L., Cheng, E., Nakajima, E., Morganti, L. and Martins, E. A. 2014. VapC from the leptospiral VapBC toxin-antitoxin module displays ribonuclease activity on the initiator tRNA. PLoS One 9, e101678.
DOI
|
17 |
Maezato, Y., Daugherty, A., Dana, K., Soo, E., Cooper, C., Tachdjian, S., Kelly, R. M. and Blum, P. 2011. VapC6, a ribonucleolytic toxin regulates thermophilicity in the crenarchaeote Sulfolobus solfataricus. RNA 17, 1381-1392.
DOI
|
18 |
Miallau, L., Faller, M., Chiang, J., Arbing, M., Guo, F., Cascio, D. and Eisenberg, D. 2009. Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis. J. Biol. Chem. 284, 276-283.
DOI
|
19 |
Masuda, H., Tan, Q., Awano, N., Yamaguchi, Y. and Inouye, M. 2012. A novel membrane-bound toxin for cell division, CptA (YgfX), inhibits polymerization of cytoskeleton proteins, FtsZ and MreB, in Escherichia coli. FEMS Microbiol. Lett. 328, 174-181.
DOI
|
20 |
McKenzie, J. L., Duyvestyn, J. M., Smith, T., Bendak, K., Mackay, J., Cursons, R., Cook, G. M. and Arcus, V. L. 2012. Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry. RNA 18, 1267-1278.
DOI
|
21 |
Sharp, J. D., Cruz, J. W., Raman, S., Inouye, M., Husson, R. N. and Woychik, N. A. 2012. Growth and translation inhibition through sequence-specific RNA binding by Mycobacterium tuberculosis VapC toxin. J. Biol. Chem. 287, 12835-12847.
DOI
|
22 |
Siboo, I. R., Chambers, H. F. and Sullam, P. M. 2005. Role of SraP, a Serine-rich surface protein of staphylococcus aureus, in binding to human platelets. Infect. Immun. 73, 2273-2280.
DOI
|
23 |
Stieber, D., Gabant, P. and Szpirer, C. 2008. The art of selective killing: plasmid toxin/antitoxin systems and their technological applications. BioTechniques 45, 344-346.
DOI
|
24 |
Suzuki, M., Zhang, J., Liu, M., Woychik, N. A. and Inouye, M. 2005. Single protein production in living cells facilitated by an mRNA interferase. Mol. Cell 18, 253-261.
DOI
|
25 |
Nariya, H. and Inouye, M. 2008. MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development. Cell 132, 55-66.
DOI
|
26 |
Park, J. H., Yamaguchi, Y. and Inouye, M. 2011. Bacillus subtilis MazF-bs (EndoA) is a UACAU-specific mRNA interferase. FEBS Lett. 585, 2526-2532.
DOI
|
27 |
Okamoto, M., Chono, H., Kawano, Y., Saito, N., Tsuda, H., Inoue, K., Kato, I., Mineno, J. and Baba, M. 2013. Sustained inhibition of HIV-1 replication by conditional expression of the E. coli-derived endoribonuclease MazF in CD4+ T cells. Hum. Gene Ther. Methods 24, 94-103.
DOI
|
28 |
Overgaard, M., Borch, J., Jorgensen, M. G. and Gerdes, K. 2008. Messenger RNA interferase RelE controls relBE transcription by conditional cooperativity. Mol. Microbiol. 69, 841-857.
DOI
|
29 |
Pandey, D. P. and Gerdes, K. 2005. Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res. 33, 966-976.
DOI
|
30 |
Wang, X., Lord, D. M., Cheng, H. Y., Osbourne, D. O., Hong, S. H., Sanchez-Torres, V., Quiroga, C., Zheng, K., Herrmann, T., Peti, W., Benedik, M. J., Page, R. and Wood, T. K. 2012. A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS. Nat. Chem. Biol. 8, 855-861.
DOI
|
31 |
Wang, X., Lord, D. M., Hong, S. H., Peti, W., Benedik, M. J., Page, R. and Wood, T. K. 2013. Type II toxin/antitoxin MqsR/MqsA controls type V toxin/antitoxin GhoT/GhoS. Environ. Microbiol. 15, 1734-1744.
DOI
|
32 |
Weaver, K. E., Ehli, E. A., Nelson, J. S. and Patel, S. 2004. Antisense RNA regulation by stable complex formation in the Enterococcus faecalis plasmid pAD1 par addiction system. J. Bacteriol. 186, 6400-6408.
DOI
|
33 |
Weaver, K. E., Weaver, D. M., Wells, C. L., Waters, C. M., Gardner, M. E. and Ehli, E. A. 2003. Enterococcus faecalis plasmid pAD1-encoded Fst toxin affects membrane permeability and alters cellular responses to lantibiotics. J. Bacteriol. 185, 2169-2177.
DOI
|
34 |
Schifano, J. M., Vvedenskaya, I. O., Knoblauch, J. G., Ouyang, M., Nickels, B. E. and Woychik, N. A. 2014. An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3. Nat. Commun. 5, 3538.
|
35 |
Ramage, H. R., Connolly, L. E. and Cox, J. S. 2009. Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution. PLoS Genet. 5, e1000767.
DOI
|
36 |
Sala, A., Bordes, P. and Genevaux, P. 2014. Multiple toxin-antitoxin systems in Mycobacterium tuberculosis. Toxins (Basel) 6, 1002-1020.
DOI
|
37 |
Schifano, J. M., Edifor, R., Sharp, J. D., Ouyang, M., Konkimalla, A., Husson, R. N. and Woychik, N. A. 2013. Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site. Proc. Natl. Acad. Sci. USA 110, 8501-8506.
DOI
|
38 |
Yamaguchi, Y., Park, J. H. and Inouye, M. 2011. Toxin-antitoxin systems in bacteria and archaea. Annu. Rev. Genet. 45, 61-79.
DOI
|
39 |
Zhang, J., Zhang, Y., Zhu, L., Suzuki, M. and Inouye, M. 2004. Interference of mRNA function by sequence-specific endoribonuclease PemK. J. Biol. Chem. 279, 20678-20684.
DOI
|
40 |
Zhang, Y. and Inouye, M. 2011. RatA (YfjG), an Escherichia coli toxin, inhibits 70S ribosome association to block translation initiation. Mol. Microbiol. 79, 1418-1429.
DOI
|
41 |
Zhang, Y., Zhang, J., Hoeflich, K. P., Ikura, M., Qing, G. and Inouye, M. 2003. MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli. Mol. Cell 12, 913-923.
DOI
|
42 |
Zhang, Y., Zhu, L., Zhang, J. and Inouye, M. 2005. Characterization of ChpBK, an mRNA interferase from Escherichia coli. J. Biol. Chem. 280, 26080-26088.
DOI
|
43 |
Vogel, J., Argaman, L., Wagner, E. G. and Altuvia, S. 2004. The small RNA IstR inhibits synthesis of an SOS-induced toxic peptide. Curr. Biol. 14, 2271-2276.
DOI
|
44 |
Unterholzner, S. J., Poppenberger, B. and Rozhon, W. 2013. Toxin-antitoxin systems: Biology, identification, and application. Mob. Genet. Elements 3, e26219.
DOI
|
45 |
Van Melderen, L., Bernard, P. and Couturier, M. 1994. Londependent proteolysis of CcdA is the key control for activation of CcdB in plasmid-free segregant bacteria. Mol. Microbiol. 11, 1151-1157.
DOI
|
46 |
Vesper, O., Amitai, S., Belitsky, M., Byrgazov, K., Kaberdina, A. C., Engelberg-Kulka, H. and Moll, I. 2011. Selective translation of leaderless mRNAs by specialized ribosomes generated by MazF in Escherichia coli. Cell 147, 147-157.
DOI
|
47 |
Williams, J. J. and Hergenrother, P. J. 2012. Artificial activation of toxin-antitoxin systems as an antibacterial strategy. Trends Microbiol. 20, 291-298.
DOI
|
48 |
Winther, K. S., Brodersen, D. E., Brown, A. K. and Gerdes, K. 2013. VapC20 of Mycobacterium tuberculosis cleaves the sarcin-ricin loop of 23S rRNA. Nat. Commun. 4, 2796.
|
49 |
Winther, K. S. and Gerdes, K. 2011. Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA. Proc. Natl. Acad. Sci. USA 108, 7403-7407.
DOI
|
50 |
Yamaguchi, Y. and Inouye, M. 2009. mRNA interferases, sequence-specific endoribonucleases from the toxin-antitoxin systems. Prog. Mol. Biol. Transl. Sci. 85, 467-500.
DOI
|
51 |
Yamaguchi, Y., Park, J. H. and Inouye, M. 2009. MqsR, a crucial regulator for quorum sensing and biofilm formation, is a GCU-specific mRNA interferase in Escherichia coli. J. Biol. Chem. 284, 28746-28753.
DOI
|
52 |
Hurley, J. M. and Woychik, N. A. 2009. Bacterial toxin HigB associates with ribosomes and mediates translation-dependent mRNA cleavage at A-rich sites. J. Biol. Chem. 284, 18605-18613.
DOI
|
53 |
Zhu, L., Inoue, K., Yoshizumi, S., Kobayashi, H., Zhang, Y., Ouyang, M., Kato, F., Sugai, M. and Inouye, M. 2009. Staphylococcus aureus MazF specifically cleaves a pentad sequence, UACAU, which is unusually abundant in the mRNA for pathogenic adhesive factor SraP. J. Bacteriol. 191, 3248-3255.
DOI
|
54 |
Zhu, L., Zhang, Y., Teh, J. S., Zhang, J., Connell, N., Rubin, H. and Inouye, M. 2006. Characterization of mRNA interferases from Mycobacterium tuberculosis. J. Biol. Chem. 281, 18638-18643.
DOI
|
55 |
de la Cueva-Mendez, G., Mills, A. D., Clay-Farrace, L., Diaz-Orejas, R. and Laskey, R. A. 2003. Regulatable killing of eukaryotic cells by the prokaryotic proteins Kid and Kis. EMBO J. 22, 246-251.
DOI
|
56 |
Dy, R. L., Richter, C., Salmond, G. P. C. and Fineran, P. C. 2014. Remarkable Mechanisms in Microbes to Resist Phage Infections. Annu. Rev. Virol. 1, 307-331.
DOI
|
57 |
Hayes, F. 2003. Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest. Science 301, 1496-1499.
DOI
|
58 |
Bertram, R. and Schuster, C. F. 2014. Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems. Front. Cell. Infect. Microbiol. 4, 6.
|
59 |
Bi, E., Dai, K., Subbarao, S., Beall, B. and Lutkenhaus, J. 1991. FtsZ and cell division. Res. Microbiol. 142, 249-252.
DOI
|
60 |
Brown, J. M. and Shaw, K. J. 2003. A novel family of Escherichia coli toxin-antitoxin gene pairs. J. Bacteriol. 185, 6600-6608.
DOI
|
61 |
Brzozowska, I. and Zielenkiewicz, U. 2013. Regulation of toxin-antitoxin systems by proteolysis. Plasmid 70, 33-41.
DOI
|
62 |
Liu, M., Zhang, Y., Inouye, M. and Woychik, N. A. 2008. Bacterial addiction module toxin Doc inhibits translation elongation through its association with the 30S ribosomal subunit. Proc. Natl. Acad. Sci. USA 105, 5885-5890.
DOI
|
63 |
Bukowski, M., Lyzen, R., Helbin, W. M., Bonar, E., Szalewska-Palasz, A., Wegrzyn, G., Dubin, G., Dubin, A. and Wladyka, B. 2013. A regulatory role for Staphylococcus aureus toxin-antitoxin system PemIKSa. Nat. Commun. 4, 2012.
|
64 |
Cook, G. M., Robson, J. R., Frampton, R. A., McKenzie, J., Przybilski, R., Fineran, P. C. and Arcus, V. L. 2013. Ribonucleases in bacterial toxin-antitoxin systems. Biochim. Biophys. Acta 1829, 523-531.
DOI
|
65 |
Lioy, V. S., Rey, O., Balsa, D., Pellicer, T. and Alonso, J. C. 2010. A toxin-antitoxin module as a target for antimicrobial development. Plasmid 63, 31-39.
DOI
|
66 |
Fineran, P. C., Blower, T. R., Foulds, I. J., Humphreys, D. P., Lilley, K. S. and Salmond, G. P. 2009. The phage abortive infection system, ToxIN, functions as a protein-RNA toxin-antitoxin pair. Proc. Natl. Acad. Sci. USA 106, 894-899.
DOI
|
67 |
Fozo, E. M., Hemm, M. R. and Storz, G. 2008. Small toxic proteins and the antisense RNAs that repress them. Microbiol. Mol. Biol. Rev. 72, 579-589.
DOI
|
68 |
Gerdes, K., Christensen, S. K. and Lobner-Olesen, A. 2005. Prokaryotic toxin-antitoxin stress response loci. Nat. Rev. Microbiol. 3, 371-382.
DOI
|
69 |
Gerdes, K., Thisted, T. and Martinussen, J. 1990. Mechanism of post-segregational killing by the hok/sok system of plasmid R1: sok antisense RNA regulates formation of a hok mRNA species correlated with killing of plasmid-free cells. Mol. Microbiol. 4, 1807-1818.
DOI
|