• 제목/요약/키워드: Neural tube

검색결과 121건 처리시간 0.024초

Deep neural network based prediction of burst parameters for Zircaloy-4 fuel cladding during loss-of-coolant accident

  • Suman, Siddharth
    • Nuclear Engineering and Technology
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    • 제52권11호
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    • pp.2565-2571
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    • 2020
  • Background: Understanding the behaviour of nuclear fuel claddings by conducting burst test on single cladding tube under simulated loss-of-coolant accident conditions and developing theoretical cum empirical predictive computer codes have been the focus of several investigations. The developed burst criterion (a) assumes symmetrical deformation of cladding tube in contrast to experimental observation (b) interpolates the properties of Zircaloy-4 cladding in mixed α+β phase (c) does not account for azimuthal temperature variations. In order to overcome all these drawbacks of burst criterion, it is reasoned that artificial intelligence technique may be a better option to predict the burst parameters. Methods: Artificial neural network models based on feedforward backpropagation algorithm with logsig transfer function are developed. Results: Neural network architecture of 2-4-4-3, that is model with two hidden layers having four nodes in each layer is found to be the most suitable. The mean, maximum, and minimum prediction errors for this optimised model are 0.82%, 19.62%, and 0.004%, respectively. Conclusion: The burst stress, burst temperature, and burst strain obtained from burst criterion have average deviation of 19%, 12%, and 53% respectively whereas the developed neural network model predicted these parameters with average deviation of 6%, 2%, and 8%, respectively.

Chiari Malformation with Surgically Induced Open Neural Tube Defect in Late Chick Embryos : Characterization by Magnetic Resonance Imaging and Histopathological Analysis

  • In Sung Hwang;Kyung Hyun Kim;Ki Bum Sim
    • Journal of Korean Neurosurgical Society
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    • 제66권4호
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    • pp.393-399
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    • 2023
  • Objective : Chiari II malformation (CM II) is still the main cause of severe morbidity and mortality in children with open neural tube defects (ONTDs). The goal of this study was to validate a CM II model in late-stage chick embryos with surgically induced ONTDs. Methods : To make the chick embryo model of ONTD, their neural tubes were opened for a length of 5-6 somites at the thoracic level in Hamburger and Hamilton stage 18 chick embryos (n=150). They were reincubated in ovo up to a total age of 17-21 days. A total of 19 embryos survived and were assigned to either the postoperative day (POD) 14-15 group (n=6) or the POD 17-18 group (n=13). Magnetic resonance imaging (MRI) and histopathologic findings of embryo heads with spinal ONTDs were compared with age-matched normal chick embryos. Results : The chick embryos with ONTDs demonstrated definite and constant structural changes, such as downward displacement of the cerebellum to just above the foramen magnum and narrow and small cerebrospinal fluid spaces in the crowded small posterior fossa. These morphologic features were more prominent in the POD 17-18 group than in the POD 14-15 group. Conclusion : This is the first description of CM II with spinal ONTD in a late-stage chick embryo model with MRI and histopathological analysis. The morphological changes of the posterior fossa in this study mimic those of CM II associated with spinal ONTD in humans. This model will facilitate investigation of the pathogenesis of CM II.

MRPC eddy current flaw classification in tubes using deep neural networks

  • Park, Jinhyun;Han, Seong-Jin;Munir, Nauman;Yeom, Yun-Taek;Song, Sung-Jin;Kim, Hak-Joon;Kwon, Se-Gon
    • Nuclear Engineering and Technology
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    • 제51권7호
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    • pp.1784-1790
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    • 2019
  • Accurate and consistent characterization of defects in steam generator tubes (SGT) in nuclear power plants is one of the key issues in the field of nondestructive testing since the large number of signals to be analyzed in a time-limited in-service inspection causes a serious problem in practice. This paper presents an effective approach to this difficult task of automated classification of motorized rotating pancake coil (MRPC) eddy current flaw acquired from tube specimens with deliberated defects using deep neural networks (DNN). This approach consists of five steps, namely, the data acquisition using the MRPC probe in the tube, the signal preprocessing to make data more suitable for training DNN, the data augmentation for boosting a training performance, the training of DNN, and finally demonstration of the trained DNN for discriminating the axial and circumferential defects. The high performance obtained in this study shows that DNN is useful for classification of defects in tubes from the MRPC eddy current signals even though the number of signals is very large.

수평원통 관에서 감온액정을 이용한 난류유동의 온도 및 속도장에 관한 실험적 연구 (An Experimental Study on Temperature and Velocity Fields of the Turbulent Flows Horizontal Cylindrical Tube by Using Thermo-sensitive Liquid Crystal)

  • 장태현;도덕희
    • Journal of Advanced Marine Engineering and Technology
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    • 제27권7호
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    • pp.921-929
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    • 2003
  • An experimental investigation was performed to study the characteristics of turbulent water flow in a horizontal circular tube by using liquid crystal. To determine some characteristics of the turbulent flow, 2D PIV technique is employed for velocity measurement and liquid crystal is used for heat transfer experiments in water. Temperature visualization was made quantitatively by calibrating the color of the liquid crystal versus temperature using various approaches (TLC technique: Thermochromic Liquid Crystal), and a neural-network algorithm was applied to the color-to-temperature calibration. This study shoud the temperature and time-mean velocity distribution for Re = 2,436, 2,500 and 2,724 along longitudinal sections and the results appear to be physically reasonable.

Coexistence of Subcutaneous Dermoid Cyst and Lipomyelomeningocele

  • Kim, Young-Hoon;Jahng, Tae-Ahn;Chung, Chun-Kee
    • Journal of Korean Neurosurgical Society
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    • 제39권4호
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    • pp.310-313
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    • 2006
  • Although lipomyelomeningocele and dermoid cyst are formed during a similar embryologic developmental stage of 'neural tube formation', they are caused by entirely different embryologic mechanisms. We encountered a case, which has not been previously reported, that had a lumbar subcutaneous dermoid cyst associated with lipomyelomeningocele. A 52-year-old man presented with a slowly growing lumbar mass of 3 years duration, which had been present since birth. Lumbosacral magnetic resonance imaging[MRI] showed lipomyelomeningocele at the L3, 4 and 5 levels and a subcutaneous cystic mass of high signal intensity on the T2 weighted image and iso or low signal intensity on the T1 weighted image. He underwent total resection of the lumbar subcutaneous mass. Intraoperative findings and histological examination were consistent with the preoperative diagnosis of a 'dermoid cyst'. We demonstrate that the formation of a dermoid cyst might coexist with lipomyelomeningocele during the embryologic developmental stage.

Clinical and Radiologic Characteristics of Caudal Regression Syndrome in a 3-Year-Old Boy: Lessons from Overlooked Plain Radiographs

  • Kang, Seongyeon;Park, Heewon;Hong, Jeana
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제24권2호
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    • pp.238-243
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    • 2021
  • Caudal regression syndrome (CRS) is a rare neural tube defect that affects the terminal spinal segment, manifesting as neurological deficits and structural anomalies in the lower body. We report a case of a 31-month-old boy presenting with constipation who had long been considered to have functional constipation but was finally confirmed to have CRS. Small, flat buttocks with bilateral buttock dimples and a short intergluteal cleft were identified on close examination. Plain radiographs of the abdomen, retrospectively reviewed, revealed the absence of the distal sacrum and the coccyx. During the 5-year follow-up period, we could find his long-term clinical course showing bowel and bladder dysfunction without progressive neurologic deficits. We present this case to highlight the fact that a precise physical examination, along with a close evaluation of plain radiographs encompassing the sacrum, is necessary with a strong suspicion of spinal dysraphism when confronting a child with chronic constipation despite the absence of neurologic deficits or gross structural anomalies.

Overview of Secondary Neurulation

  • Catala, Martin
    • Journal of Korean Neurosurgical Society
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    • 제64권3호
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    • pp.346-358
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    • 2021
  • Secondary neurulation is a morphological process described since the second half of the 19th century; it accounts for the formation of the caudal spinal cord in mammals including humans. A similar process takes place in birds. This form of neurulation is caused by the growth of the tail bud region, the most caudal axial region of the embryo. Experimental work in different animal species leads to questioning dogmas widely disseminated in the medical literature. Thus, it is clearly established that the tail bud is not a mass of undifferentiated pluripotent cells but is made up of a juxtaposition of territories whose fate is different. The lumens of the two tubes generated by the two modes of neurulation are continuous. There seem to be multiple cavities in the human embryo, but discrepancies exist according to the authors. Finally, the tissues that generate the secondary neural tube are initially located in the most superficial layer of the embryo. These cells must undergo internalization to generate the secondary neurectoderm. A defect in internalization could lead to an open neural tube defect that contradicts the dogma that a secondary neurulation defect is closed by definition.

One-dimensional CNN Model of Network Traffic Classification based on Transfer Learning

  • Lingyun Yang;Yuning Dong;Zaijian Wang;Feifei Gao
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제18권2호
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    • pp.420-437
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    • 2024
  • There are some problems in network traffic classification (NTC), such as complicated statistical features and insufficient training samples, which may cause poor classification effect. A NTC architecture based on one-dimensional Convolutional Neural Network (CNN) and transfer learning is proposed to tackle these problems and improve the fine-grained classification performance. The key points of the proposed architecture include: (1) Model classification--by extracting normalized rate feature set from original data, plus existing statistical features to optimize the CNN NTC model. (2) To apply transfer learning in the classification to improve NTC performance. We collect two typical network flows data from Youku and YouTube, and verify the proposed method through extensive experiments. The results show that compared with existing methods, our method could improve the classification accuracy by around 3-5%for Youku, and by about 7 to 27% for YouTube.

열충격 및 ${\alpha}$-amanitin과 cycloheximide의 처리를 통한 초기 계배의 체절 형성 기작에 대한 발생학적 연구 (Embryological Studies on Somitogenesis of Early Chick Embryos by heat shock and treatments of ${\alpha}$-amanitin and cycloheximide)

  • 최임순;박용빈;김옥용
    • Applied Microscopy
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    • 제21권2호
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    • pp.1-13
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    • 1991
  • In order to investigate the factors of the control mechanism of somitogenesis, early chick embryos (H-H stage $8{\sim}13$) were treated with heat shock, ${\alpha}$-amanitin and cycloheximide and morphological changes of somite were examined by light microscopy, transmission and scanning electron microscopy. In normal chick embryo, somites were formed from the somitomere which preexisted in segmental plate. Somites were wrapped with extracellular collagen fibrils and connected with neural tube, notochord and ectoderm. And then, somites were differentiated to sclerotome, dermatome and myotome by the interaction of nervous tissue. Abnormal somites were observed after formation of six or seven so mites in heat shock treated group. Amounts of collagen fibrils were obviously decreased in this group. In cycloheximide treated group, most so mites were smaller and neural tube formation was incomplete. Chromatins were condenced and formed several heterochromatins in the nucleus of somite cells. Lipid like cytoplasmic dense mass and lipid droplets were also observed. Segmentation of somites seemed to be normal progress in ${\alpha}$-amanitin treated group. Center of somite, however, hollowed in longitudinal sectioned samples. These results suggested that so mites were already existed in the segmental plate as the form of somitomere. Segmented somites were contacted with neural tube or notochord and the somites were tightly connected with each other by the extracellular collagen fibrils which were secreted from neuroepithelium and somite cells. Somites are thought to differentiate into sclerotome, dermatome and myotome by these interactions.

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신경회로망을 이용한 원전SG 세관 결함크기 예측 (Prediction of Defect Size of Steam Generator Tube in Nuclear Power Plant Using Neural Network)

  • 한기원;조남훈;이향범
    • 비파괴검사학회지
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    • 제27권5호
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    • pp.383-392
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    • 2007
  • 본 논문에서는 신경회로망을 이용하여 원자력 발전소 증기발생기 세관의 결함 깊이와 폭을 예측하는 연구를 수행한다. 결함 크기 추정을 위하여 우선, I-In 형태, I-Out 형태, V-In 형태, V-Out 형태의 4가지 결함형상에 대한 와전류탐상시험(ECT) 신호를 생성한다. 특히, 유한요소법에 기반한 수치해석 기법을 이용하여 여러 가지 폭과 깊이를 갖는 결함 400개의 ECT 신호를 생성한다. 이와 같이 생성된 ECT 신호로부터, 결함 크기와 폭을 예측하기 위한 새로운 특징벡터를 추출하는데, 이 특징벡터에는 최대 임피던스 값을 갖는 점과 최대 임피던스값의 1/2의 값을 갖는 점 사이의 위상각이 포함된다. 추출된 특징벡터를 이용하여 결함의 크기를 예측하기 위해서 하나의 은닉층을 갖는 다층퍼셉트론을 이용하였다. 컴퓨터 모의실험 연구를 통하여 제안된 방법이 우수한 예측성능을 갖는다는 것을 보였다.