• 제목/요약/키워드: Network Mining

검색결과 1,053건 처리시간 0.032초

Comparative co-expression analysis of RNA-Seq transcriptome revealing key genes, miRNA and transcription factor in distinct metabolic pathways in diabetic nerve, eye, and kidney disease

  • Asmy, Veerankutty Subaida Shafna;Natarajan, Jeyakumar
    • Genomics & Informatics
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    • 제20권3호
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    • pp.26.1-26.19
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    • 2022
  • Diabetes and its related complications are associated with long term damage and failure of various organ systems. The microvascular complications of diabetes considered in this study are diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. The aim is to identify the weighted co-expressed and differentially expressed genes (DEGs), major pathways, and their miRNA, transcription factors (TFs) and drugs interacting in all the three conditions. The primary goal is to identify vital DEGs in all the three conditions. The overlapped five genes (AKT1, NFKB1, MAPK3, PDPK1, and TNF) from the DEGs and the co-expressed genes were defined as key genes, which differentially expressed in all the three cases. Then the protein-protein interaction network and gene set linkage analysis (GSLA) of key genes was performed. GSLA, gene ontology, and pathway enrichment analysis of the key genes elucidates nine major pathways in diabetes. Subsequently, we constructed the miRNA-gene and transcription factor-gene regulatory network of the five gene of interest in the nine major pathways were studied. hsa-mir-34a-5p, a major miRNA that interacted with all the five genes. RELA, FOXO3, PDX1, and SREBF1 were the TFs interacting with the major five gene of interest. Finally, drug-gene interaction network elucidates five potential drugs to treat the genes of interest. This research reveals biomarker genes, miRNA, TFs, and therapeutic drugs in the key signaling pathways, which may help us, understand the processes of all three secondary microvascular problems and aid in disease detection and management.

aCN-RB-tree: Constrained Network-Based Index for Spatio-Temporal Aggregation of Moving Object Trajectory

  • Lee, Dong-Wook;Baek, Sung-Ha;Bae, Hae-Young
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제3권5호
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    • pp.527-547
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    • 2009
  • Moving object management is widely used in traffic, logistic and data mining applications in ubiquitous environments. It is required to analyze spatio-temporal data and trajectories for moving object management. In this paper, we proposed a novel index structure for spatio-temporal aggregation of trajectory in a constrained network, named aCN-RB-tree. It manages aggregation values of trajectories using a constraint network-based index and it also supports direction of trajectory. An aCN-RB-tree consists of an aR-tree in its center and an extended B-tree. In this structure, an aR-tree is similar to a Min/Max R-tree, which stores the child nodes' max aggregation value in the parent node. Also, the proposed index structure is based on a constrained network structure such as a FNR-tree, so that it can decrease the dead space of index nodes. Each leaf node of an aR-tree has an extended B-tree which can store timestamp-based aggregation values. As it considers the direction of trajectory, the extended B-tree has a structure with direction. So this kind of aCN-RB-tree index can support efficient search for trajectory and traffic zone. The aCN-RB-tree can find a moving object trajectory in a given time interval efficiently. It can support traffic management systems and mining systems in ubiquitous environments.

A Fusion of Data Mining Techniques for Predicting Movement of Mobile Users

  • Duong, Thuy Van T.;Tran, Dinh Que
    • Journal of Communications and Networks
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    • 제17권6호
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    • pp.568-581
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    • 2015
  • Predicting locations of users with portable devices such as IP phones, smart-phones, iPads and iPods in public wireless local area networks (WLANs) plays a crucial role in location management and network resource allocation. Many techniques in machine learning and data mining, such as sequential pattern mining and clustering, have been widely used. However, these approaches have two deficiencies. First, because they are based on profiles of individual mobility behaviors, a sequential pattern technique may fail to predict new users or users with movement on novel paths. Second, using similar mobility behaviors in a cluster for predicting the movement of users may cause significant degradation in accuracy owing to indistinguishable regular movement and random movement. In this paper, we propose a novel fusion technique that utilizes mobility rules discovered from multiple similar users by combining clustering and sequential pattern mining. The proposed technique with two algorithms, named the clustering-based-sequential-pattern-mining (CSPM) and sequential-pattern-mining-based-clustering (SPMC), can deal with the lack of information in a personal profile and avoid some noise due to random movements by users. Experimental results show that our approach outperforms existing approaches in terms of efficiency and prediction accuracy.

Environmental Consciousness Data Modeling by Association Rules

  • Park, Hee-Chang;Cho, Kwang-Hyun
    • Journal of the Korean Data and Information Science Society
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    • 제16권3호
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    • pp.529-538
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    • 2005
  • Data mining is the method to find useful information for large amounts of data in database. It is used to find hidden knowledge by massive data, unexpectedly pattern, relation to new rule. The methods of data mining are association rules, decision tree, clustering, neural network and so on. Association rule mining searches for interesting relationships among items in a riven large data set. Association rules are frequently used by retail stores to assist in marketing, advertising, floor placement, and inventory control. There are three primary quality measures for association rule, support and confidence and lift. We analyze Gyeongnam social indicator survey data using association rule technique for environmental information discovery. We can use to environmental preservation and environmental improvement by association rule outputs.

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SEISMIC MONITORING IN SURFACE MINES

  • Ajay Kumar, L.;David Raj, D. Edwin;Renaldy, T. Amrith;Vinoth, S.
    • 터널과지하공간
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    • 제19권3호
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    • pp.174-180
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    • 2009
  • This paper gives a brief review of seismicity and seismic monitoring in surface mines. A summary of various researches related to seismicity is presented. Our research focuses on the understanding of seismicity and the application of analytical techniques to seismicity. Seismic monitoring plays an important role in the identification of potential failure planes and thereby predict potential failures. Much of the instrumentation used in our research is derived from earthquake monitoring systems. The major aspects in seismic monitoring are an instrumentation used, size of the network and data acquisition systems. Seismic monitoring in surface mines could be successfully applied to the improvement of safety standards in slope stability.

데이터 마이닝을 이용한 생산공정 데이터 분석 시나리오 (Scenarios for Manufacturing Process Data Analysis using Data Mining)

  • 이형욱;배성민
    • 융복합기술연구소 논문집
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    • 제3권1호
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    • pp.41-44
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    • 2013
  • Process and manufacturing data are numerously accumulated to the enterprise database in industries but little of those data are utilized. Data mining can support a decision to manager in process from the data. However, it is not easy to field managers because a proper adoption of various schemes is very difficult. In this paper, six scenarios are conducted using data mining schemes for the various situations of field claims such as yield problem, trend analysis and prediction of yield according to changes of operating conditions, etc. Scenarios, like templates, of various analysis situations are helpful to users.

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데이터 마이닝 기반의 6 시그마 방법론 : 철강산업 적용사례 (A Six Sigma Methodology Using Data Mining : A Case Study of "P" Steel Manufacturing Company)

  • 장길상
    • 한국정보시스템학회지:정보시스템연구
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    • 제20권3호
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    • pp.1-24
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    • 2011
  • Recently, six sigma has been widely adopted in a variety of industries as a disciplined, data-driven problem solving approach or methodology supported by a handful of powerful statistical tools in order to reduce variation through continuous process improvement. Also, data mining has been widely used to discover unknown knowledge from a large volume of data using various modeling techniques such as neural network, decision tree, regression analysis, etc. This paper proposes a six sigma methodology based on data mining for effectively and efficiently processing massive data in driving six sigma projects. The proposed methodology is applied in the hot stove system which is a major energy-consuming process in a "P" steel company for improvement of heat efficiency through reduction of energy consumption. The results show optimal operation conditions and reduction of the hot stove energy cost by 15%.

Environmental Consciousness Data Modeling by Association Rules

  • 박희창;조광현
    • 한국데이터정보과학회:학술대회논문집
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    • 한국데이터정보과학회 2004년도 추계학술대회
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    • pp.115-124
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    • 2004
  • Data mining is the method to find useful information for large amounts of data in database. It is used to find hidden knowledge by massive data, unexpectedly pattern, relation to new rule. The methods of data mining are association rules, decision tree, clustering, neural network and so on. Association rule mining searches for interesting relationships among items in a given large data set. Association rules are frequently used by retail stores to assist in marketing, advertising, floor placement, and inventory control. There are three primary quality measures for association rule, support and confidence and lift. We analyze Gyeongnam social indicator survey data using association rule technique for environmental information discovery. We can use to environmental preservation and environmental improvement by association rule outputs.

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데이터 마이닝을 위한 이동 에이전트의 효율적인 이주 전략 (An Efficient Migration Strategy of Mobile Agents for Data Mining)

  • 권혁찬;유우종;김흥환;유관종
    • 한국정보처리학회논문지
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    • 제7권5호
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    • pp.1511-1519
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    • 2000
  • 본 논문에서는 데이터 마이닝 (data mining)을 위한 이동 에이전트의 효율적인 이주 전략 알고리즘을 제시한다. 제시한 알고리즘의 목적은 최소의 네트워크 소요시간을 갖도록 이동 에이전트의 이주 계획을 세우는 것이다. 본 논문의 이주 간략 일고리즘을 검증하고 평가하기 우해 데이터 마이닝을 수행하기 위한 세 가지 패러다임-RPC(Remote Procodure Call),이 등 에지전트, locker 패턴이 적용된 이동 에이전트에 대한 수행 평가 모델을 제시하였으며, 시뮬레이션을 수행하여 알고리즘을 평가하였다.

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Association Rule of Gyeongnam Social Indicator Survey Data for Environmental Information

  • Park, Hee-Chang;Cho, Kwang-Hyun
    • Journal of the Korean Data and Information Science Society
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    • 제16권1호
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    • pp.59-69
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    • 2005
  • Data mining is the method to find useful information for large amounts of data in database It is used to find hidden knowledge by massive data, unexpectedly pattern, relation to new rule. The methods of data mining are decision tree, association rules, clustering, neural network and so on. We analyze Gyeongnam social indicator survey data by 2001 using association rule technique for environment information. Association rule mining searches for interesting relationships among items in a given large data set. Association rules are frequently used by retail stores to assist in marketing, advertising, floor placement, and inventory control. There are three primary quality measures for association rule, support and confidence and lift. We can use to environmental preservation and environmental improvement by association rule outputs

  • PDF