• IMMUNE NETWORK
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• v.6 no.4
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• pp.192-198
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• 2006

Background: Investigating strategy to enhance efficiency of gene transfer via adenovirus is critical to sustain gene expression in targeted cells or tissues to regulate immune responses. However, the use of adenovirus as a gene delivery method has been limited by the native tropism of the virus. In this study, the critical parameter is to improve the efficient binding of viral particles to the plasma membrane prior to cellular uptake. Methods: Human immunodeficiency virus (HIV-1) trans-acting activator of transcription (TAT), a protein transduction domain, was fused to the ectodomain of the coxsackie-adenovirus receptor (CAR). The CAR-TAT protein was produced from a Drosophila Schneider 2 cells (S2) transfected with CAR-TAT genes. The function of CARTAT was analyzed the efficiency of adenoviral gene transfer by flow cytometry, and then immunizing AdVGFP with CAR-TAT was transduced on dendritic cells (DCs). Results: S2 transfectants secreting CAR-TAT fusion protein has been stable over a period of 6 months and its expression was verified by western blot. Addition of CAR-TAT induced higher transduction efficiency for AdVGFP at every MOI tested. When mice were vaccinated with DC of which adenoviral transduction was mediated by CAR-TAT, the number of IFN-${\gamma}$ secreting T-cells was increased as compared with those DCs transduced without CAR-TAT. Conclusion: Our data provide evidence that CAR-TAT fusion protein enhances adenoviral transduction and immunogenecity of transgenes on DCs and may influence on the development of adenoviral-mediated anti-tumor immunotherapy.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.47 no.4
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• pp.71-81
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• 2010

In grid system, Task scheduling based on list scheduling models has showed low complexity and high efficiency in fully connected processor set environment. However, earlier schemes did not consider sufficiently the communication cost among tasks and the composition process of lightpath for communication in optical gird environment. In this thesis, we propose LSOG (Leveling Selection in Optical Grid) which sets task priority after forming a hierarchical directed acyclic graph (DAG) that is optimized in optical grid environment. To determine priorities of task assignment in the same level, proposed algorithm executes the task with biggest communication cost between itself and its predecessor. Then, it considers the shortest route for communication between tasks. This process improves communication cost in scheduling process through optimizing link resource usage in optical grid environment. We compared LSOG algorithm with conventional ELSA (Extended List Scheduling Algorithm) and SCP (Scheduled Critical Path) algorithm. We could see the enhancement in overall scheduling performance through increment in CCR value and smoothing network environment.

• Management & Information Systems Review
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• v.28 no.3
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• pp.191-210
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• 2009

Internet was first designed only for sending data, but as the time passed, internet started to evolve into a broadband multi-media web that is capable of transmitting sound, video, high-capacity data and more due to the demands of internet users and the rapid changing internet-communication technology. Domestically, in January, 2000 Saerom C&T, launched a free VoIP, but due to limited ways of conversation(PC to PC) and absence of a revenue model, and bad speech quality, it had hit it's growth limit. This research studied VoIP based on technological enhancement in super-speed internet. According to IDC, domestic internet market's size was 80,800 million in 2008, and it formed a percentage of 12.5% out of the whole sound-communication market. in case of VoIP, it is able to maximize it's profit by connecting cable and wireless network, also it has a chance of becoming firm-concentrated monopoly market by fusing with IPTV. Considering the fact that our country is insignificant in MVNO revitalization, regulating organizations will play a significant roll on regulating profit between large and small businesses. Further research should be done to give VoIP a secure footing to prosper and become popularized.

• Journal of Agricultural Extension & Community Development
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• v.21 no.4
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• pp.1191-1226
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• 2014

The purpose of this study is to develop the evaluation criteria for the maintenance preserve of agriculture and rural heritage. The major steps for this study are 1) drafting the evaluation criteria for maintenance preservation of agriculture and rural heritage 2) verifying the evaluation criteria, and 3) determining the weighting values of the confirmed evaluation criteria. First, to derive the evaluation criteria for maintenance preservation of agriculture and rural heritage, the researcher reviewed the literature on the evaluation of agriculture and rural heritage, including research on the indexes of agriculture and rural heritage, the degree of the maintain preservation of heritage. A total of 31 evaluation criteria were selected. Second, to verify the selected 5 evaluation items and 31 evaluation indexes, the Delphi Method was implemented. Using traditional 3-step Delphi Method consisting of close-ended forms, with a panel of 41 experts, the researchers verified 5 evaluation items 31 evaluation indexes, two for each evaluation area validity. The confirmed evaluation areas are 5 items of management plan, management support system, surroundings of heritage, local network, heritage utilization and 31 criteria were preservation maintenance, performance plan, resident community composition, monitoring, act of parliament fulfillment, ecosystem management, landscape harmony, restoration and transmission plan and enhancement of residents' capability, etc. in the order. Through maintenance preservation evaluation index of agriculture and rural heritage, it can be utilized as sustainable development of plural resources.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.7 no.1
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• pp.71-82
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• 1996

In this paper, the Doppler phase error due to the relative velocity between a satellite and the earth station in communications using a low earth orbit mobile satellite is detected. The performance of BPSK system in the presence of Rician fading with Doppler phase error and interference, noise is compared with that of the system disturbed by Doppler phase error and noise only. The expression of error rate performance of BPSK system is derived as the type of complementary error function. The numerical calculation of the induced equation are performed in terms of satellite-height, orbit-eccentricity, the velocity of the earth, Rician fading parameter, signal to interference rateio (SIR), the ratio of carrier frequency and base band bit rate. The main conclusion that can be drawn from this analysis is that Rician fading channel environment with Doppler phase error and interference effect yields severe performance degradation than Do- ppler phase error and noise effect in satellite communication channel. And using the numerical calculation, we give a quantitative insight how much the satellite communication channel parameters degrade the system performance. Furthermore it is shown that an appropriate transmission power control for the performance enhancement is beneficial to the new satellite communication system planning.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.7 no.2
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• pp.128-138
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• 1996

In this paper, the Doppler phase error due to the relative velocity between a satellite and the earth station in communications using a low earth orbit mobile satellite is detected. The performance of BPSK system in the presence of Rician fading channel environment with Doppler phase error, inter- ference and noise is compared with that of the system disturbed by Doppler phase error and noise only, And adopted coding techniques are Hamming, BCH, RS and convolution codes. The expression of error rate performance of BPSK system is derived as the type of complementary error function. The main conclusion that can be drawn from this analysis is that Rician fading channel environment with Do- ppler phase error and interference, noise effect yields severe performance degradation then Doppler phase error and noise effect in satellite communication channel. The conclusion can be drawn from this analysis is that using coding technique then noncoding. And using the numerical calculation, we give a quantitative insight how much the satellite communication channel parameters degrade the system per- formance. Furthermore it is shown that an appropriate transmission power control for the performance enhancement is beneficial to the new satellite communication system planning.

• Journal of Digital Contents Society
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• v.10 no.4
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• pp.639-648
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• 2009

Earth's environment issues are introduced recently and every year the social loss have been occurred by the impact of various disaster. This kind of disaster and weather problems are the increasing reason of electricity transmission network equipment's failures because of exposing by the natural environment. The emergency and abnormal status of electricity equipment make the power outage of manufacturing plant and discomfort of people's lives. So, to protect the electricity equipment from the natural disasters and to supply the power to customer as stable, the supporting systems are required. In this paper, the research results are described the development process and the outcomes of the real-time natural disaster failure analysis information system including the describing about the impact of disaster and weather change, making the natural weather information, and linking the realtime monitoring system. As of development process, according to application development methodology, techniques are enumerated including the real time interface with related systems, the analysing the geographic information on the digital map using GIS application technology to extract the malfunction equipment potentially and to manage the equipments efficiently. Through this system makes remarkable performance it minimize the failures of the equipments, the increasing the efficiency of the equipment operation, the support of scientific information related on the mid-term enhancement plan, the savings on equipment investment, the quality upgrading of electricity supply, and the various supports in the field.

• Korea journal of population studies
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• v.12 no.1
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• pp.104-142
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• 1989

IndustrialiBation and urbanisation have been known to increase divorce rates through the enhancement of emotional function of flmily, the weakness of extendedfamilial network, the separation of public and private spheres, increase of educationallevel for women, increase of labor participation rate for women, and the pursuit ofegalitarian relationship for the couple. Divorce rates by sex, age, province andeducation in Korea for the period 1970 ~ 1995 were examined using the data ofmarriage and divorce registration and population census. Crude divorce rates, sex-age-specific divorce rates and sex-age-adjusted divorce rates were calculated for thetotal population and the married population respectively, and the characteristics ofvarious divorce indicators were discussed. During 1970~1995, divorce rates increasedthree times, and divorce rate in 1995 was 3.5 per 1,000 married persons. Divorcerate was highest for those under 25 years old, and it was increasing rapidly fDr allages, with the most rapid increase fDr the middle-aged. The relative divorce increaserate was highest fDr females than males. Divorce rates were highest for Seoul, Pusan,Inchon, Taejon, Kyonggi, and Jeju, and for aged 25 ~ 34 years of Chonbuk andKangwon. Divorce rate was highest fDr the male elementary-school graduates andlowest for the male college graduates, it was highest for the female high-schoolgraduates and lowest for the female uneducated.

• Journal of Home Health Care Nursing
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• v.10 no.1
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• pp.5-14
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• 2003

Recently, there has been an increasing need for long-term care and comprehensive health care services in community settings. The Ministry of Health and Welfare introduced the Hospital-Based Home Nursing Care Program in 2000. Before this initiative, there was a Home Nursing Demonstration Center, affiliated with the Seoul Nurse Association, had offered home nursing services with the financial support from the local government. since 1993, the Center's nursing staff has been engaged in a general hospital in an effort to provide home nursing care services within Korea's health care system. The purpose of this study was to analyze and identify characteristics of community-based home nursing care supplied by a community-based home nursing team engaged in a general hospital. Also. visit nursing care services provided by public health centers were evaluated in terms of accessibility and supply versus demand, to enhance the accessibility of low-income patients living in Seoul to home nursing care services. Data were collected from home nursing insurance reimbursement claims submitted by the community-based home nursing care team from March 1 to October 30 in 2001 and a questionnaire survey on home-visit nursing services of 25 public health centers in Seoul. The subjects consisted of 197 patients and 12 public health centers. The result were as follows. First, medical institution's community-based home nursing care program was better in technical quality than health-center-based home-visit nursing care. In addition. the pattern of the subject patients was similar to that of hospital-based home nursing care program. Second, there was a high demand for community-based home nursing care while only a small number of home-visiting nurses served at public health centers in Seoul. As a result, many patients could not receive adequate care. Finally, we suggest that community-based home nursing care program should be introduced in the national health system to meet the at-home care needs of severely ill low-income patients. Furthermore, to better utilize home nursing and visit-nursing care resources and offer continued care for patients in community settings, an efficient referral network should be built among related institutions. This would require improvement of reimbursement system and amendment of the law related to health insurance system and community-based home nursing care services.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.322-331
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• 2013

The purpose of the present study was to develop a convergent education contents for dementia prevention, operating on the web network applying modern information technology(IT). At the preparation stage, local and worldwide literatures related to dementia were analyzed followed by surveying industry demands, based on which the program was designed and developed. In the following enhancement stage, the program was modified as much as possible by advices obtained from experts in various fields. Development results of the present program are summarized as follows. Firstly, 645 intellect development model to prevent dementia was established through peer review and verification of convergent education theories by expert groups. This model was named as "Garisani" meaning "cognition capable of judging objects" in the Korean language. Secondly, 'Find a way' and 'Connect a line' modules were developed in the numeric field as well as 'Identify a letter(I, II)' modules, in the language field for web-based left brain training program. Thirdly, 'Find my car' and 'Vision training' modules in the attention field and 'Object inference' and 'Compare pictures' modules in the cognition field were developed for web-based right brain training program. Fourth, 'Pentomino' and 'BQmaze'(Brain Quotient and maze) modules in the space perception field and 'Visual training' in the memory field were developed for web-based left and right brains training. Fifth, all results were integrated leading to a 52 week Garisani convergent education program for dementia prevention.