• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 춘계학술대회
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• pp.67-70
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• 2015

정보통신(ICT)산업의 빠른 진화 속도에 따라, ICT 산업을 뒷받침할 인력양성(HRD)의 필요성이 꾸준히 대두 되고 있다. 특히 우리나라의 경우, 유엔 전자정부발전지수 연속1위, ITU의 ICT개발지수 2위등 우수한 공공인프라를 유지하고 있고, 학계에서는 ICT전공자를 꾸준히 배출함에도 불구하고, 해당 산업계에서의 만족도는 많은 차이(Gap)가 있어서 산업계 스스로 재교육이나 이에 따른 사회적 비용이 부가적으로 존재하고 있는 실정이다. 이러한 현상은 다른 나라에서도 동일한 사회적 현상이다. 이에, ICT산업 종사자 및 소프트웨어 개발자가 비즈니스를 이해하고, 요구사항에 따른 과제를 해결하여 산업계 진입 후, 특정 직무나 직위에 상관없이 비즈니스 요구에 따른 문제를 해결하고 업무를 성공적으로 수행하는데 요구되는 기본적인 핵심적 지식, 스킬, 태도의 종합적인 능력수준을 진단하고 평가하는 제도와 도구의 필요성이 대두되어 왔다, 이에 본 논문에서는 IT공통역량 강화를 도모하는 교수-학습-실무현장을 위한 제도, 개념 및 구조, 정책과 영향에 따라 개발된 제도적 시스템을 소개하고 결과를 평가한다. 이 시스템은 ITU-ASP 주관 ICTD-USO포럼 기간 중 초청 소개 되었고, 주요 ASEAN국가들의 관심과 지원요청을 받았다.

• Asian-Australasian Journal of Animal Sciences
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• 제15권1호
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• pp.72-78
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• 2002

The effects of housing and nutrition on the performance of growing gilts of the Nepalese Pakhribas breed were investigated. A total of 36 pigs were allocated according to a factorial design with 3 levels of nutrition, provided to achieve a target growth rate of 200, 300 or 400 g/day, and two types of housing, traditional or improved. The growth rate and body composition were monitored during the growing period and subsequent pregnancy. There was a significantly higher growth rate (p<0.01), greater $P_2$ backfat thickness (p<0.01), and greater eye muscle depth (p<0.01) at service in pigs given the higher level of nutrition. Similarly, there was a significantly higher growth rate (p<0.05), and greater eye muscle depth (p<0.10) with improved housing but no significant difference in $P_2$ backfat thickness. The conception rate was 90% at first service, with no difference between treatments. Gilts from the high plane of rearing produced a mean litter size of one piglet greater than those on the low plane, but this was not significant with the limited numbers. However, both improved plane of nutrition and reduced climatic penalty by improving housing resulted in increased birthweight of piglets (p<0.05). It is concluded that improvement in housing can give benefits equivalent to at least a 7% improvement in efficiency of feed use under traditional Nepalese circumstances for pig rearing.

• 대한임상독성학회지
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• 제4권1호
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• pp.78-81
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• 2006

Mad-honey poisoning is mainly brought about by the honey imported from Napal, Turkey, Brazil and other parts of Europe. This mad honey is extracted from Ericaceae plants of Rhododendron species and contains grayanotoxins that causes poisoning. These toxic compounds exert a specific stimulatory action on membrane permeability to Na+ions in various excitable tissues and cause depolarization of cell membranes. The toxic effects of grayanotoxins contained honey are mainly cardiovascular disturbances with bradycardia, cardiac arrhythmia, hypotension. There are Other symptoms like nausea, vomiting, salivation, dizziness, weakness and loss of consciousness. The precise amount for a toxic dose is not known. In general the severity of the honey poisoning depends on the amount ingested. Two cases of mad-honey poisoning are described here. Both patients showed bradycardia and arterial hypotension after ingestion of honey which was brought from Nepal. They were recovered fully within 24 hours after administration of fluids and atropine sulphate.

• 과학기술학연구
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• 제13권2호
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• pp.1-35
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• 2013

이 글은 한국에서의 적정기술에 대한 논의와 실천이 기술중심적이고 기술개발(제공)자 중심적인 접근에 국한된 상대적으로 좁은 범위에서 이루어지고 있다는 성찰 위에서, 기술을 둘러싼 사회적, 제도적인 측면과 기술 수용자의 측면을 강조하는 사회-기술 시스템적인 시각에서 적정기술을 통한 국제개발협력 활동을 논의할 필요성을 제기한다. 이를 위해서 우선 적정기술을 기술사회 시스템 논의에 비춰 볼 때 검토해 볼 몇 가지 쟁점-적정기술은 수준 낮은 수준인가? 적정기술 실천은 단위 기술 혹은 제품을 제공하는 것인가? 적정기술은 개발도상국 사람들의 기본적인 필요만을 충족시키기 위한 것인가?-에 대해 논의하였다. 이어 개발도상국-라오스, 태국, 방글라데시-에서 이루어지는 (재생)에너지와 관련한 현지 단체들의 적정기술 실천을 앞서 정리한 쟁점을 중심으로 살펴보면서 사회기술적 시스템적 접근의 의미를 구체적으로 논의해보았다. 다음으로 한국의 적정기술 담론을 비판적으로 평가하는 한편, 민간 국제개발협력 활동 중 재생에너지 관련 사례-몽골의 G-Saver, 네팔과 라오스의 태양광 발전기-를 통해 적정기술 실천의 현황에 대해서 검토하고자 했다. 마지막으로 국내외 사례를 종합하면서, 한국 국제개발협력 활동에서 적정기술 접근을 수용하기 위해 고려해야 할 점에 대해서 몇가지 제안하고, 추후 연구과제를 정리하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1829-1832
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• 2016

Background: Breast cancer is the second most common malignancy among Nepalese women, accounting for 60% of the total cancer cases in females. Women diagnosed with germline mutations in BRCA1 like 185delAG, 1294del40 develop breast and/or ovarian cancer with a lifelong likelihood of up to 85% whereas presence of a mutation increases the risk for mutations to occur in other genes. The major objective of this study was to find the prevalence of these mutations in Nepalese cancer patients. Materials and Methods: This prospective study was carried out at two cancer hospitals in the Kathmandu valley over a period of 11 months. Irrespective of age group and stage of canceran appropriate amount of blood was withdrawn from 50 breast cancer patients and 20 controls. DNA was extracted manually and subjected to PCR using primers for 185delAG and 1294del40 mutations. PCR products were then digested with restriction enzyme (DdeII) followed by electrophoresis. Results: Prevalence of 185delAG in reference breast cancer patients was found to be 4/50 (8%) but no 1294del40 was apparent. Conclusions: Several mutations occurring in different exons of BRCA1 as well as mutations in other genes like BRCA2, for example, should also be taken in account.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.1031-1033
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• 2014

Aim: To investigate the effect of hyperglycemia and hyperinsulinemia on prostate cancer risk. Materials and Methods: This hospital based study was carried out using data retrieved from the register maintained in the Department of Biochemistry of a tertiary care hospital of Kathmandu, Nepal between $31^{st}$ December, 2011 and $31^{st}$ October, 2013. The variables collected were age, serum cholesterol, serum calcium, PSA, fasting blood glucose, serum insulin. Analysis was performed by descriptive statistics and testing of hypothesis using Excel 2003, R 2.8.0, Statistical Package for the Social Sciences (SPSS) for Windows Version 16.0 (SPSS Inc; Chicago, IL, USA) and the EPI Info 3.5.1 Windows Version. Results: Of the total 125 subjects enrolled in our present study, 25 cases were of PCa and 100 were healthy controls. The mean value of fasting plasma glucose was 95.5 mg/dl in cases of prostatic carcinoma and the mean value of fasting plasma insulin was $5.78{\mu}U/ml$ (p value: 0.0001*). The fasting insulin levels ${\mu}U/ml$ were categorized into the different ranges starting from ${\leq}2.75$, >2.75 to ${\leq}4.10$, >4.10 to ${\leq}6.10$, > $6.10{\mu}U/ml$. The maximum number of cases of prostatic carcinoma of fasting insulin levels falls in range of > $6.10{\mu}U/ml$. The highest insulin levels (> $6.10{\mu}U/ml$) were seen to be associated with an 2.55 fold risk of prostatic carcinoma when compared with fasting insulin levels of (< $2.75{\mu}U/ml$). Conclusions: Elevated fasting levels of serum insulin appear to be associated with a higher risk of prostate cancer.

• 대기
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• 제21권3호
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• pp.301-309
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• 2011

In this study, we compared light-absorption properties of aerosols observed in East and South Asia from black carbon (BC) mass concentration, aerosol scattering (${\sigma}_s$) and absorption (${\sigma}_a$) coefficients measurements at four sites: Korea Climate Observatory-Gosan (KCO-G), Korea Climate Observatory-Anmyeon (KCO-A), Maldives Climate Observatory-Hanimaadhoo (MCO-H) and Nepal Climate Observatory-Pyramid (NCO-P). No significant seasonal variations of BC mass concentration, ${\sigma}_s$ and ${\sigma}_a$, despite of wet removal of aerosols by precipitation in summer, were observed in East Asia, whereas dramatic changes of light-absorbing aerosol properties were observed in South Asia between dry and wet monsoon periods. Although BC mass concentration in East Asia is generally higher than that observed in South Asia, BC mass concentration at MCO-H during winter dry monsoon is similar to that of East Asia. The observed solar absorption efficiency (${\alpha}$) at 550 nm, where ${\alpha}={\sigma}_a/({\sigma}_s+{\sigma}_a)$, at KCO-G and KCO-A is higher than that in MCO-H due to large portions of BC emission from fossil fuel combustion. Interestingly, ${\alpha}$ at NCO-P is 0.14, which is two times great than that in MCO-H and is about 40% higher than that in East Asia, though BC mass concentration at NCO-P is the lowest among four sites. Consistently, the highest elemental carbon to sulphate ratio is found at NCO-P.

• 대한한의학방제학회지
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• 제24권4호
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• pp.323-333
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• 2016

Objectives : The purpose of this study was to investigate musk deer in taxonomic status and genus species. We investigated the characteristic of musk deer for medicinal usages. Methods : To identifications of musk deer on the taxonomic status and genus species, the literary investigation were conducted on the Korean, China, and Japan pharmacopoeia and published herbal books, CITES Species Lists too. Results : Musk deer placement in a separate family status is the Moschidae. M. chrysogaster Hodgson and M. sifanicus Przewalski was the same species. So, Alpine musk deer revised M. chrysogaster Hodgson[=M. sifanicus Przewalski]. Geographic distribution of M. moschiferus L. divided Sibirica group and himalaica group. Group himalaica contains three subspecies: Korean musk deer(M. moschiferus parvipes Hol.), Chinese musk deer(M. chrysogaster Hodgson), and Himalayan musk deer(M. leucogaster Hodgson). The genetic divergence between M. moschiferus L. and other species was clearly distinguished from the others. M. berezovskii Flerove was less than the others. However, the divergence among M. chrysogaster Hodgson, M. fuscus Li, and M. leucogaster Hodgson were quite low. Musk deers are mostly distributed around the high-plateau. Moschus were from Nepal, Bhutan, Russia, China. Forest musk deer(M. berezovskii Flerove) farming was conducted in China from 1950s. In the Korean hebal pharmacopoeia, Moschus include l-muscone($C_{16}H_{30}O$ : 238.40) over 2% for quantitative test. Conclusions : There are three species of musk deer, Siberian musk deer(M. moschiferus L.), forest musk deer(M. berezovskii Flerove), and Alpine musk deer(M. chrysogaster Hodgson) for medicinal usages.

• Biomolecules & Therapeutics
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• 제19권1호
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• pp.70-76
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• 2011

Bone remodeling is a dynamic process involving a constant balance between osteoclast-induced bone resorption and osteoblast-induced bone formation. Osteoclasts play a crucial homeostatic role in skeletal modeling and remodeling, and destroy bone in many pathological conditions. Previously, we reported that the hexane soluble fraction of Ficus carica inhibited osteoclast differentiation. Poly unsaturated fatty acids, such as ethyl docosahexaenoate (E-DHA), docosahexaenoic acid (DHA), cis-11,14-eicosadienoic acid (EDA) and eicosapentaenoic acid (EPA), were identified from the hexane soluble fraction of Ficus carica. Among them, E-DHA most potently inhibited osteoclastogenesis in RAW264.7 cells. E-DHA reduced the activities of JNK and NF-$\kappa}B$. E-DHA suppressed the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1). Interestingly, DHA increased the activity of alkaline phosphatase and expression of bone morphogenetic protein 2 (BMP2) more than E-DHA in MC3T3-E1 cells, suggesting that DHA may induce osteoblast differentiation. The data suggests that a combination of E-DHA and DHA has potential use in the treatment of diseases involving abnormal bone lysis, such as osteoporosis, rheumatoid arthritis and periodontal bone erosion.

• 한국작물학회지
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• 제55권1호
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• pp.47-57
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• 2010

More than 2,500 accessions of squash germplasm are preserved in the National Agrobidiversity Center of RDA, Korea. We investigated the ecological and morphological characteristics on 100 accessions of the squash germplasms with a low viability. Two typical types of oriental squash (Cucurbita moschata) and western squash (Cucurbita maxima) are possessed 89 and 11 accessions, respectively. The origin of 100 accessions was divided into three groups, group I (Korea landraces with 81 accessions), group II (Nepal with 15 accessions) and group III (Russia, Uzbekistan, Laos, and Mexico with each one accession). Seventy eight accessions germinated at $27^{\circ}C$ in growth chamber. Days to first flowering of the female and male flower ranged from 32 days to 67 days and 24 days to 55 days after planting, respectively. Vine length showed the largest variation ranging from 357.8 cm to 1,465 cm, also the average length of ten stem node range has a variable ranges from 92 cm to 217.5 cm. All regenerated squash accessions have an only collided tendril and have three to seven lateral shoots. The flattened globe-shaped squash is the most predominant and exhibited ordinarily round shaped, ball shaped, long oblong-shaped, elongated shape, and pear shape. The average weight of fruit ranged from 1.33 kg to 7.95 kg. Sugar contents showed 5.4~12.6 $Brix^{\circ}$ without ripening period.