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Thallium poisoning: a case report

  • Oscar Jimenez;Hector Caceres;Luis Gimenez;Luciana Soto;Micaela Montenegro;Jhon Alexander Avila Rueda
    • Journal of Yeungnam Medical Science
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    • v.40 no.3
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    • pp.311-314
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    • 2023
  • Thallium poisoning is usually accidental. We present a case of a 51-year-old woman who was evaluated in June 2018 for myalgia, vertigo, asthenia, and abdominal pain. Physical examination revealed temporal-spatial disorientation, jaundice, and asterixis. The laboratory reported the following: bilirubin, 10.3 mg/dL; aspartate transaminase, 78 U/L; alanine transaminase, 194 U/L; albumin, 2.3 g/dL; prothrombin time, 40%; and platelet count, 60,000/mm3. Serology performed for hepatitis A, B, and C; Epstein-Barr virus; cytomegalovirus; and human immunodeficiency virus was negative, and a collagenogram was negative. Physical reevaluation revealed alopecia on the scalp, armpits, and eyebrows; macules on the face; plantar hyperkeratosis; and ulcers on the lower limbs. Tests for lead, arsenic, copper, and mercury were carried out, which were normal; however, elevated urinary thallium (540 ㎍/g; range, 0.4-10 ㎍/g) was observed. The patient was treated with D-penicillamine 1,000 mg/day and recovered her urinary thallium levels were within normal range at annual follow-up. Thallium poisoning is extremely rare and can be fatal in small doses. An adequate clinical approach can facilitate early diagnosis.

ON REFORMULATED INJECTIVE CHROMATIC INDEX OF GRAPHS

  • SALEH, ANWAR;AQEEL, A.;ALASHWALI, HANAA
    • Journal of applied mathematics & informatics
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    • v.39 no.1_2
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    • pp.13-29
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    • 2021
  • For a graph G = (V, E), a vertex coloring (or, simply, a coloring) of G is a function C : V (G) → {1, 2, …, k} (using the non-negative integers {1, 2, …, k} as colors). We say that a coloring of a graph G is injective if for every vertex v ∈ V (G), all the neighbors of v are assigned with distinct colors. The injective chromatic number χi(G) of a graph G is the least k such that there is an injective k-coloring [6]. In this paper, we study a natural variation of the injective coloring problem: coloring the edges of a graph under the same constraints (alternatively, to investigate the injective chromatic number of line graphs), we define the k- injective edge coloring of a graph G as a mapping C : E(G) → {1, 2, …, k}, such that for every edge e ∈ E(G), all the neighbors edges of e are assigned with distinct colors. The injective chromatic index χ′in(G) of G is the least positive integer k such that G has k- injective edge coloring, exact values of the injective chromatic index of different families of graphs are obtained, some related results and bounds are established. Finally, we define the injective clique number ωin and state a conjecture, that, for any graph G, ωin ≤ χ′in(G) ≤ ωin + 2.

Antimicrobial susceptibility and prevalence of gram-negative bacteria isolated from bovine mastitis (젖소 유방염으로부터 분리한 그람음성균의 분포 및 항생제 감수성)

  • Lee, Eun-Sil;Kang, Hyun-Mi;Chung, Chung-il;Moon, Jin-San
    • Korean Journal of Veterinary Research
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    • v.47 no.1
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    • pp.67-75
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    • 2007
  • Environmental mastitis has increased particularly in well-managed or low somatic cell countherds that have successfully controled contagious pathogens. Major pathogens of environmental mastitisare Escherichia coli (E. coli) and Streptococcus uberis. The present study was conducted to investigate1,865 quaters of 241 Korean dairy farms from 2001 to 2004. Prevalence of major gram-negative bacteriaisolated from mastitis milk were E. coli (22.7%) and Enterobacter spp. (16.3%) in coliforms and Pseudomoassp. (10.3%) and Serratia spp. (7.9%) in non-coliforms. The results on antibiotic susceptibility by agardifusion test against these pathogens were 86.7% in piperaciliin, 94.6% in cefepime, 85.5% in amikacin,87.7% in gentamicin and so on. In contrast, the susceptibility against ampicillin (41.9%), cephalothin (9.9%),streptomycin (39.9%) and tetracycline (46.7%) appeared to be below 50%. Gram-negative bacteria showed(96.8%). Acording to year, distribution of high $256{\sim}64{\mu}g/ml$ on cephalothin get increased, but the othersare diferent. These findings demonstrate that major gram-negative bacteria were E. coli and Enterobacterspp. isolates, and often encountered the diverse antibiotic resistant patterns.

DISTANCE TWO LABELING ON THE SQUARE OF A CYCLE

  • ZHANG, XIAOLING
    • Korean Journal of Mathematics
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    • v.23 no.4
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    • pp.607-618
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    • 2015
  • An L(2; 1)-labeling of a graph G is a function f from the vertex set V (G) to the set of all non-negative integers such that ${\mid}f(u)-f(v){\mid}{\geq}2$ if d(u, v) = 1 and ${\mid}f(u)-f(v){\mid}{\geq}1$ if d(u, v) = 2. The ${\lambda}$-number of G, denoted ${\lambda}(G)$, is the smallest number k such that G admits an L(2, 1)-labeling with $k=\max\{f(u){\mid}u{\in}V(G)\}$. In this paper, we consider the square of a cycle and provide exact value for its ${\lambda}$-number. In addition, we also completely determine its edge span.

ON RICCI CURVATURES OF LEFT INVARIANT METRICS ON SU(2)

  • Pyo, Yong-Soo;Kim, Hyun-Woong;Park, Joon-Sik
    • Bulletin of the Korean Mathematical Society
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    • v.46 no.2
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    • pp.255-261
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    • 2009
  • In this paper, we shall prove several results concerning Ricci curvature of a Riemannian manifold (M, g) := (SU(2), g) with an arbitrary given left invariant metric g. First of all, we obtain the maximum (resp. minimum) of {r(X) := Ric(X,X) | ${||X||}_g$ = 1,X ${\in}$ X(M)}, where Ric is the Ricci tensor field on (M, g), and then get a necessary and sufficient condition for the Levi-Civita connection ${\nabla}$ on the manifold (M, g) to be projectively flat. Furthermore, we obtain a necessary and sufficient condition for the Ricci curvature r(X) to be always positive (resp. negative), independently of the choice of unit vector field X.

Effect of Grape Seed Proanthocyanidins on Tumor Vasculogenic Mimicry in Human Triple-negative Breast Cancer Cells

  • Luan, Yun-Yan;Liu, Zi-Min;Zhong, Jin-Yi;Yao, Ru-Yong;Yu, Hong-Sheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.531-535
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    • 2015
  • Vasculogenic mimicry (VM) refers to the unique ability of highly aggressive tumor cells to mimic the pattern of embryonic vasculogenesis, which was associated with invasion and metastasis. The grape seed proanthocyanidins (GSPs) had attracted much attention as a potential bioactive anti-carcinogenic agent. However, GSPs regulation of VM and its possible mechanisms in a triple-negative breast cancer cells (TNBCs) remain not clear. Therefore, we examined the effect of GSPs on VM information in HCC1937 cell model. In this study, we identified the VM structure via the three-dimensional (3D) matrix in vitro. Cell viability was measured using the CCK8 assay. The effects of GSPs on human triple-negative breast cancer cells (TNBCs) HCC1937 in terms of related proteins of VM information were determined using western blot analysis. In vitro, the tubular networks were found in highly invasive HCC1937 cells but not in the non-invasive MCF-7 cells when plated on matrigel. The number of vascular channels was significantly reduced when cells were exposed in GSPs ($100{\mu}g$/ml) and GSPs ($200{\mu}g/mL$) groups (all p<0.001). Furthermore, we found that treatment with GSPs promoted transition of the mesenchymal state to the epithelial state in HCC1937 cells as well as reducing the expression of Twist1 protein, a master EMT regulator.GSPs has the ability to inhibit VM information by the suppression of Twist1 protein that could be related to the reversal of epithelial-to-mesenchymal (EMT) process. It is firstly concluded that GSPs may be an p otential anti-VM botanical agent for human TNBCs.

Psychophysiological Reactivity to Affective Visual Stimulation of Negative Emotional Valence: Comparative Analysis of Autonomic and Frontal EEG Responses to the IAPS and the KAPS

  • Sohn, Jin-Hun;Estate M. Sokhadze;Lee, Kyung-Hwa
    • Science of Emotion and Sensibility
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    • v.3 no.2
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    • pp.29-40
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    • 2000
  • Autonomic and EEG responses were analyzed in 32 college students exposed to visual stimulation with Korean Affective Picture System (KAPS) and 36 students exposed to the International Affective Picture System (IAPS). Cardiac, electrodermal, and electrocortical measures were recorded during 30 sec of viewing affective pictures. The slides intended to elicit basic emotions (fear, anger, surprise, disgust, and sadness) were presented to subjects via Kodak slide-projector. The aim of the study was to differentiate autonomic and EEG responses associated with the same negative valence emotions elicited by KAPS and IAPS stimulation and to identify the influence of cultural relevance on physiological reactivity. The analysis of obtained results revealed significant differences in physiological responsiveness to emotionally negative valence slides from KAPS and IAPS. The typical response profile for all emotions elicited by the KAPS included HR acceleration (except surprise), and increase of electrodermal activity, slow and fast alpha blocking and fast beta power increase in EEG, which was not associated with significant asymmetry (except fast alpha in sadness). Stimulation with the IAPS evoked HR deceleration, specific electrodermal responses with relatively high tonic electrodermal activation, alpha-blocking and fast beta increase, and was accompanied also by theta power increase and marked frontal asymmetry (e.g., fast beta, theta asymmetries in sadness, fast alpha in fear). Physiological responses to fear and anger-eliciting slides from the IAPS were significantly less profound and were accompanied by autonomic and EEG changes more typical for attention rather than negative affect. Higher cardiovascular and electrodermal reactivity to fear emotion observed in the KAPS, e.g., as compared to data with the IAPS as stimuli, can be explained by cultural relevance and higher effectiveness of the KAPS in producing certain emotions such as fear in Koreans.

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The Effects of Client Violence on the Burnout of Social Workers Working for Social Welfare Facilities - Focusing on the moderating effects of Institutional confrontation system and demographic characteristic - (사회복지시설 클라이언트의 폭력에 대한 종사자의 반응이 직무소진에 미치는 영향 - 시설의 대응체계와 인구통계적 특성의 조절효과를 중심으로 -)

  • Jung, Eun-Mee;Park, Hwie-Seo
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.5
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    • pp.173-183
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    • 2011
  • The purpose of this study is to suggest the policy implications through the analysis on the effects of social workers' negative reactions for client violence on burnout. Especially, This study is focused on identifying the moderating effects of demographic characteristics and institutional confrontations system. This study was carried out based on survey of social workers on social welfare facilities located in G metropolitan city and J province. The major findings can be summarized as follows. First, Social workers' negative reactions toward client violence affect on burnout significantly. Second, demographic characteristics and institutional confrontations system moderate the relationship between social workers' negative reactions toward client violence and their burnout. This study suggested some implications basing on the analytical results.

Affective Metaphor of Dimensional Perception (물리적 차원 지각에 대한 감성 메타포)

  • Mun, Sung-Chul;Whang, Min-Cheol;Lee, Jung-Nyun;Kim, Jong-Hwa;Kim, Ji-Hye
    • Journal of the Ergonomics Society of Korea
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    • v.30 no.1
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    • pp.187-193
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    • 2011
  • Objective: The aim of this study was to investigate the association between conceptual metaphors of affect and physical dimensions. Background: The evidence that affect is unconsciously linked to physical dimensions(e.g., position and color) has been obtained in western cultures. However, in eastern cultures, especially, in Korea, it has been seldom tested. It is indispensable to examine whether or not cultural differences exist for better understanding of the conceptual metaphors. Method: 50 positive and 50 negative words were adopted from previous studies in order to determine the relationship between physical domains and abstract affect. Three hypotheses were tested in this study: (1) Good is up. (2) Good is bright. (3) Good is right(for right-handers). The automatic association between valence(positive vs. negative) and vertical position (up vs. down) was investigated in experiment 1, in which 100 words were randomly presented on either the top or the bottom of a LCD screen and the evaluation time of the presented word was recorded. The unconscious association between valence and color(white and black) was examined in experiment 2, where each word was randomly presented in either white or black. Lastly, we tested whether right-handers tend to associate rightward space with positive ideas and leftward space with negative ideas. Results: Reaction time was faster when words were presented in metaphor congruent domains(e.g., 'positive words on the top, in bright color, and on right space vs. negative words on the bottom, in dark color, and on left region) than when they were shown in metaphor incongruent domains. Conclusion: The results might give the groundwork for various directions in further understanding perception, emotion, and behavior. Application: This study may provide useful points to GUI designers and service developers if further studies enhanced in validity and reliability are followed.

The Influence of Stress and Emotion Regulation Ability of Health College Students on University Life Adjustment (보건계열 대학생들의 스트레스와 정서조절에 따른 대학생활적응 관련성 연구)

  • Kang, Hyun-Joo
    • Journal of the Korea Convergence Society
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    • v.12 no.9
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    • pp.65-71
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    • 2021
  • The purpose of this study is to investigate the factors that affect stress, emotional regulation, and adjustment to college life of health college students. The survey was conducted from June 21 to 30, 2021 for 190 health students in G and J area. The data were analyzed by frequency analysis, reliability analysis, simple correlation analysis, and multiple regression analysis. The results showed that positive perception had positive correlation with negative perception(r=-.286,p<.01), emotional regulation (r=.296,p<.01), and university life adjustment(r=.520,p<.01). Negative perception was correlated with emotional regulation(r=-.619,p<.01), university life adjustment (r=-.428,p<.01) and negative(-). Emotional regulation had a positive correlation with university life adjustment(r=.341,p<.01). Positive perception, negative perception, and emotional regulation, which are sub-factors of perceived stress, were the factors affecting the adjustment to university life, and the explanatory power was 84%. Therefore, it is necessary to develop a program that can improve the adjustment of college students in health.