• Asian-Australasian Journal of Animal Sciences
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• 제32권3호
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• pp.350-356
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• 2019

Objective: To examine the regulatory effects of exercise on myokine expression in horse skeletal muscle cells, we compared the expression of several myokine genes (interleukin 6 [IL-6], IL-8, chemokine [C-X-C motif] ligand 2 [CXCL2], and chemokine [C-C motif] ligand 4 [CCL4]) after a single bout of exercise in horses. Furthermore, to establish in vitro systems for the validation of exercise effects, we cultured horse skeletal muscle cells and confirmed the expression of these genes after treatment with hydrogen peroxide. Methods: The mRNA expression of IL-6, IL-8, CXCL2, and CCL4 after exercise in skeletal muscle tissue was confirmed using quantitative-reverse transcriptase polymerase chain reactions (qRT-PCR). We then extracted horse muscle cells from the skeletal muscle tissue of a neonatal Thoroughbred. Myokine expression after hydrogen peroxide treatments was confirmed using qRT-PCR in horse skeletal muscle cells. Results: IL-6, IL-8, CXCL2, and CCL4 expression in Thoroughbred and Jeju horse skeletal muscles significantly increased after exercise. We stably maintained horse skeletal muscle cells in culture and confirmed the expression of the myogenic marker, myoblast determination protein (MyoD). Moreover, myokine expression was validated using hydrogen peroxide ($H_2O_2$)-treated horse skeletal muscle cells. The patterns of myokine expression in muscle cells were found to be similar to those observed in skeletal muscle tissue. Conclusion: We confirmed that several myokines involved in inflammation were induced by exercise in horse skeletal muscle tissue. In addition, we successfully cultured horse skeletal muscle cells and established an in vitro system to validate associated gene expression and function. This study will provide a valuable system for studying the function of exercise-related genes in the future.

• 디지털콘텐츠학회 논문지
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• 제18권8호
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• pp.1529-1535
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• 2017

혜성은 그 특유의 조형성과 신비로움으로 인하여 다양한 창작 분야에 영감을 주는 주요한 모티브로서 작용하고 있다. 현대 과학 기술의 발전과 그 맥락을 함께하며 계속해서 변화, 확장되는 미디어 아트는 테크놀로지의 활용을 통해 혜성의 구조와 같은 고유 특성까지 작품 내에 모티브로서 표현하는 형태를 보이고 있다. 본 연구는 혜성의 특성을 모티브로 하여 관객이 작품에 근접하면 상호작용이 일어나 관객에게 혜성의 꼬리를 만드는 주체가 되는 경험을 제공하는 거리 인식 기반 인터랙티브 미디어 아트 작품 "Near by"를 제작하는 과정을 기술한 연구이다. 본 작품은 관객이 가까이 다가온 것이 인식되면 혜성의 핵을 표현한 LED 구조물에 색 변화가 일어남과 동시에 구조물의 뒤로 꼬리를 표현한 영상이 프로젝션 되는 구조로 이루어져 있으며, 이러한 상호 작용 과정을 통해 관객들로 하여금 혜성에 대한 인식을 새롭게 하고 작품과 감성적으로 교감할 수 있도록 하고자 하였다. 단순히 혜성의 조형적 특성 뿐 아니라 혜성의 형성 과정까지 작품의 모티브로서 담아내고자 시도하였으며, 이러한 복합적인 모티브 표현 방법을 제안함을 통해 향후 미디어 아트 분야에 있어 자연 현상 모티브의 표현 범위를 확장시킬 수 있는 가능성을 제시하고자 한다.

• 대한가정학회지
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• 제49권8호
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• pp.13-24
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• 2011

This paper purports to find the characteristics of blue costumes as expressed in modern fashion. As such, we made an empirical analysis, using 436 works from 2006 S/S through 2010 F/W collections. Result indicated that modernness was emphasized by applying a minimum expressive technique to items of a simple form, and an image of simplicity was emphasized by placing focus on the rational color image of blue. Second, images of blue, such as trust, stability, and success were expressed as refined elegance through the combination of tight silhouettes, glossy and translucent materials, and indirect exposure. Third, natural image was expressed through natural silhouettes, soft or natural materials, gradation of various tones, and natural motif decorations as well as the color itself. Fourth, dynamic image was expressed by introducing fashion items, mostly worn by men only, to simple and tight forms or through the inspiration of a masculine fashion image. Fifth, abstinent image was expressed by using an image of religious apparel or symbols, covering up the body, minimizing details, and using a dark blue tone.

• Bulletin of the Korean Chemical Society
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• 제30권12호
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• pp.2867-2868
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• 2009

• International Journal of Costume and Fashion
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• 제12권2호
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• pp.67-82
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• 2012

21st century is the Age of Culture, and a period that is represented by symbolism and imagery. This is no exception for the countries that want to enhance their image in the international community. In order for a country to improve its brand, it has to select a representative emblem, symbols and cultural items. The usual suspects for this are its name, flag, and anthem. Each of these items can elicit different types of symbolism. It can also be used to differentiate the country from others; however, these are not the only sources of symbolism at the country's disposal. Other popular tools include cultural heritage, both tangible and intangible, climate, natural environment, and its national character. A country can use these items to associate itself with certain images. The purpose of this study is to find an objective way to effectively boost Korea's brand. This will be done by comparing and contrasting the ways countries including Korea have used their national emblems to enhance their image. Data from each of the countries were collected and analyzed. The results of this study will become empirical evidence in researches aimed to develop fashion designs that use Korea's national emblem as its motif in order to improve its national brand Countries that were used for this research were United States, United Kingdom, Japan, France and Korea, and they were chosen because their national brand rated highly. The items selected for the analysis were scarves and neckties. This was because, compared to other fashion items, it was easier to sort out scarves and neckties that used motifs of national emblems as well as these two items having the highest usage rate of this type of motif. Group of experts looked through a combined total of 370 scarves and ties and they analyzed the following factors in the design: type of motifs, frequency, use of color, methods of expression and images.

• 한국의류산업학회지
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• 제10권6호
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• pp.857-863
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• 2008

The purpose of this study is to analyze the types of Hibiscus patterns expressed on Aloha shirts. This study analyzed real data collected from man's aloha shirts displayed at the International Market Place in Waikiki of Hawaii during January 21-27, 2007. 35 pieces of Aloha shirts with Hibiscus Patterns were was analyzed. The total of each analysis means all number of patterns sampled or appeared to analyze the types of patterns. The motif of Hibiscus was sampled a total of 42 units for some shirts having several motifs. Its motif was divided into two groups, 20 units(47.62%) of natural type and 22 units(52.38%) of stylized type, according to modeling. Two types were much the same percentage. Hibiscus patterns were classified into three groups, isolated, band and arabesque type, by formation type. The isolated type was appeared most frequently. The layout of Hibiscus pattern was classified into three groups, engineered print, all over print and border print. All over print was appeared most frequently. The data of this study will be provided as a resource to promote using and developing of the pattern of Korean rose of Sharon.

• 한국잠사학회:학술대회논문집
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• 한국잠사학회 2003년도 International Symposium of Silkworm/Insect Biotechnology and Annual Meeting of Korea Society of Sericultural Science
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• pp.78-79
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• 2003

To further understanding of the role of calreticulin in insects, we have isolated a cDNA of calreticulin from silkworm, Bombyx mori. The cDNA encodes a 398 amino acid residues of B. mori calreticulin with endoplasmic reticulum retentional HDEL motif at its C-terminus, and a predicted molecular mass of 45801 Da. The B. mori calreticulin shows high protein homology with those of G mellonella (88%), A. aegypti (71%) and H. sapiens (63%). (omitted)

• Molecules and Cells
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• 제44권7호
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• pp.444-457
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• 2021

Although the mechanism of chronic myeloid leukemia (CML) initiation through BCR/ABL oncogene has been well characterized, CML cell differentiation into erythroid lineage cells remains poorly understood. Using CRISPR-Cas9 screening, we identify Chromobox 8 (CBX8) as a negative regulator of K562 cell differentiation into erythrocytes. CBX8 is degraded via proteasomal pathway during K562 cell differentiation, which activates the expression of erythroid differentiation-related genes that are repressed by CBX8 in the complex of PRC1. During the differentiation process, the serine/threonine-protein kinase PIM1 phosphorylates serine 196 on CBX8, which contributes to CBX8 reduction. When CD235A expression levels are analyzed, the result reveals that the knockdown of PIM1 inhibits K562 cell differentiation. We also identify TRIM28 as another interaction partner of CBX8 by proteomic analysis. Intriguingly, TRIM28 maintains protein stability of CBX8 and TRIM28 loss significantly induces proteasomal degradation of CBX8, resulting in an acceleration of erythroid differentiation. Here, we demonstrate the involvement of the CBX8-TRIM28 axis during CML cell differentiation, suggesting that CBX8 and TRIM28 are promising novel targets for CML research.

• 대중서사연구
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• 제25권4호
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• pp.135-158
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• 2019

본고의 목적은 기예르모 델 토로의 <판의 미로>(2006)를 환상영화로 평가하게 해주는 특성과 그것에 밀접하게 결부되어 나타나는 미궁의 모티프의 의미와 기능을 고찰하는 데 있다. 츠베탕 토도로프는 '환상적인 것'을 현실에 침입한 초자연적인 사건에 직면하여 자연적 해석과 초자연적 해석 사이에서 겪는 망설임이라고 정의하였는데, <판의 미로>는 그 망설임이 사라져 환상적인 것이 '기이'장르나 '경이'장르로 들어가도록 하지 않고 그 상태가 그대로 유지되도록 하기 때문에 이 영화에서는 환상성이 계속해서 잘 드러난다. 이때 미궁은 환상계로 들어가는 통로이자 그것을 대표하는 공간으로서 예술을 상징한다. 로즈메리 잭슨은 환상이 "문화적 속박으로부터 비롯된 결핍을 보상하려고 하는 욕망의 문학"이어서 무의식적 제재들을 반복적으로 다룬다고 보았는데, 델 토로의 영화는 환상 세계에서 가족 로맨스가 이루어지도록 함으로써 욕망의 표현으로서의 환상의 특성을 잘 보여준다. 이때 미궁은 욕망의 장소로서 마음을 상징한다. 캐스린 흄은 환상이 미메시스와 같이 현실에 대한 반응이자 '일치된 현실로부터의 이탈'이라고 정의하였는데, 이 영화는 '비전'장르로서 '대조'의 방법을 통해 환상계가 현실계를 비추도록 함으로써 그 정의를 충족시키고 그것이 가진 환상성을 돋보이게 한다. 이때 미궁은 현실계의 거울로서 세계를 상징한다. 이처럼 <판의 미로>는 환상적인 것이 매우 효과적으로 기능한다는 점에서 환상영화를 대표할 만하며, 이 영화에 나타난 미궁은 예술, 세계, 마음의 세 가지를 모두 상징하여 의미가 충만한 모티프라고 평가할 수 있다. 본고의 의의는 위와 같은 고찰을 통해 한 모티프가 특정 장르에서 작용하는 방식을 조명한 데 있다.

• 한국의상디자인학회지
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• 제19권2호
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• pp.15-28
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• 2017

Today, modern people are exposed to various environmental pollutants such as harmful substances and stress, which can compromise health. Therefore, a healing culture that seeks to enjoy human life based on the healing of body and mind is attracting great attention. The purpose of this study is to develop environmentally friendly natural dyeing considering a healing concept with four elements: color, dye, material, and pattern. The research methods and scope are based on a theoretical review of healing and research on the literature of bedding related to natural dyes, national and international books, the Internet, etc., and naturally dyed bedding. This paper presents actual production research. The results of this study are as follows. First, the elements of color, dyeing, material and pattern were developed through the process of a bedding design development model that applies a healing concept and can be commercialized as a healing bedding product. Second, a healing color proposal was expressed in an intermediate color system of pink, ocher, lavender, and indigo colors for emotional stability, warmth, calmness, comfort and softness. Third, eco-friendly bedding using natural dyes with medicinal efficacy can obtain the healing effect of the natural treatment method, which can aid healthy sleep. Fourth, the pattern used in the bedclothes was a motif of Sarasa embroidery, flower embroidery, ribbon embroidery, and wave quilting motifs to provide psychological stability as a healing concept in the sleeping environment. The natural healing bedding with the healing concept proposed in this study has natural treatment that is beneficial to human health and the development of bedding with natural dyes will lead to an increase of demand for the sleeping environment.