• Title/Summary/Keyword: Natural Breaks

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Use of Molecular Replacement to Determine the Phases of Crystal Structure of Taq DNA Polymerase

  • Kim, Young-Soo;Suh, Se-Won
    • BMB Reports
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    • v.29 no.1
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    • pp.38-44
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    • 1996
  • Taq DNA polymerase from Thermus aquaticus has been shown to be very useful in the polymerase chain reaction method, which is being used for amplifying DNA. Not only does Taq DNA polymerase have high commercial value commercial value for the polymerase chain reaction application, but it is also important in studying DNA replication, because it is apparently an homologue to E. coli DNA polymerase I, which has long been used for DNA replication study (Lawyer et ai., 1993). The crystal structure determination of Taq DNA polymerase was initiated. An X-ray diffraction pattern breaks down a crystal structure into discrete sine waves in a Fourier series. The original shape of a crystal object in terms of electron density may be represented as the sum of those sine waves with varying amplitudes and phases in three dimensions. The molecular replacement method was initially employed to provide phase information for the structure of Taq DNA polymerase. The rotation search using the program MERLOT resulted in a solution peak with 5.4 r.m.s. PC-refinement of the X-PLOR program verified the result and also optimized the orientation angles. Next, the translation search using the X-PLOR program resulted in a unique solution peak with 7.35 r.m.s. In addition, the translation search indicated $P3_121$ to be the true space group out of two possible ones. The phase information from the molecular replacement was useful in the MIR phasing experiment.

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The effects of active release technique on the gluteus medius for pain relief in persons with chronic low back pain

  • Tak, Sajin;Lee, Yongwoo;Choi, Wonjae;Lee, Gyuchang
    • Physical Therapy Rehabilitation Science
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    • v.2 no.1
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    • pp.27-30
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    • 2013
  • Objective: Low back pain is a primary of source of dysfunction and economic costs. Gluteus medius muscle co-activation and activity pattern change caused the low back pain. Active release technique (ART) is a patented, non-invasive, soft tissue treatment process that both locates and breaks down the scar tissue and adhesions. The purpose of this study was to assess the effects on chronic low back pain using ART on gluteus medius so that suggest usable treatment method for treating chronic low back pain. Design: One group pretest-posttest design. Methods: Twelve patients with chronic low back pain were participated in this study. Subjects in ART group were received 2 times a week for 3 weeks treatments with either ART on gluteus medius muscle trigger points. Outcome measures were conducted by pain intensity with a pain visual analogue scale and pressure pain threshold on gluteus medius. Results: Completion of the intervention, the visual analogue scale was decreased in ART group (p<0.05). Also pressure pain threshold was decreased in ART group (p<0.05). Conclusions: Our results suggest that the response to ART may be usable to treat low back pain. ART was presented to reduce pain level of low back in people with chronic low back pain. Further study is required to management for low back pain due to gluteus medius and more ART study.

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NEWLY DISCOVERED z ~ 5 QUASARS BASED ON DEEP LEARNING AND BAYESIAN INFORMATION CRITERION

  • Shin, Suhyun;Im, Myungshin;Kim, Yongjung;Jiang, Linhua
    • Journal of The Korean Astronomical Society
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    • v.55 no.4
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    • pp.131-138
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    • 2022
  • We report the discovery of four quasars with M1450 ≳ -25.0 mag at z ~ 5 and supermassive black hole mass measurement for one of the quasars. They were selected as promising high-redshift quasar candidates via deep learning and Bayesian information criterion, which are expected to be effective in discriminating quasars from the late-type stars and high-redshift galaxies. The candidates were observed by the Double Spectrograph on the Palomar 200-inch Hale Telescope. They show clear Lyα breaks at about 7000-8000 Å, indicating they are quasars at 4.7 < z < 5.6. For HSC J233107-001014, we measure the mass of its supermassive black hole (SMBH) using its C IV λ1549 emission line. The SMBH mass and Eddington ratio of the quasar are found to be ~108 M and ~0.6, respectively. This suggests that this quasar possibly harbors a fast growing SMBH near the Eddington limit despite its faintness (LBol < 1046 erg s-1). Our 100% quasar identification rate supports high efficiency of our deep learning and Bayesian information criterion selection method, which can be applied to future surveys to increase high-redshift quasar sample.

Vibration Control of a Beam with a Tip Mass using a Lightweight Piezo-composite Actuator (경량 압전 복합재료 작동기를 이용한 끝단 질량이 부착된 보의 진동 제어)

  • Martua, Landong;Park, Hoon-Cheol;Goo, Nam-Seo
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.35 no.3
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    • pp.218-224
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    • 2007
  • Although piezoelectric materials such as PZT have been widely used as actuators in the field of active vibration suppression, the use of bare PZT as an actuator may cause some drawbacks such as critical breaks in the installation process, short circuits in the host material and low fatigue performance. The LIPCA-C2 (lightweight piezocomposite actuator) was developed to alleviate these problems. We implemented the LIPCA as an actuator to suppress the vibration of an aluminum cantilever beam with a tip mass. In our test, we used positive position feedback control algorithm. The filter frequency for this type of feedback should be tuned to the natural frequency of the target mode. The first three experimental natural frequencies of the aluminum cantilever beam agree well with the results of finite element analysis. The effectiveness of using the LIPCA as an actuator in active vibration suppression was investigated with respect to the time and frequency domains, and the experimental results show that LIPCAs with PPF control can significantly reduce the amplitude of forced vibrations and the settling time of free vibrations. For a case study, the forced vibration control of several beams with different thicknesses were performed.

Industrial Safety Risk Analysis Using Spatial Analytics and Data Mining (공간분석·데이터마이닝 융합방법론을 통한 산업안전 취약지 등급화 방안)

  • Ko, Kyeongseok;Yang, Jaekyung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.4
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    • pp.147-153
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    • 2017
  • The mortality rate in industrial accidents in South Korea was 11 per 100,000 workers in 2015. It's five times higher than the OECD average. Economic losses due to industrial accidents continue to grow, reaching 19 trillion won much more than natural disaster losses equivalent to 1.1 trillion won. It requires fundamental changes according to industrial safety management. In this study, We classified the risk of accidents in industrial complex of Ulju-gun using spatial analytics and data mining. We collected 119 data on accident data, factory characteristics data, company information such as sales amount, capital stock, building information, weather information, official land price, etc. Through the pre-processing and data convergence process, the analysis dataset was constructed. Then we conducted geographically weighted regression with spatial factors affecting fire incidents and calculated the risk of fire accidents with analytical model for combining Boosting and CART (Classification and Regression Tree). We drew the main factors that affect the fire accident. The drawn main factors are deterioration of buildings, capital stock, employee number, officially assessed land price and height of building. Finally the predicted accident rates were divided into four class (risk category-alert, hazard, caution, and attention) with Jenks Natural Breaks Classification. It is divided by seeking to minimize each class's average deviation from the class mean, while maximizing each class's deviation from the means of the other groups. As the analysis results were also visualized on maps, the danger zone can be intuitively checked. It is judged to be available in different policy decisions for different types, such as those used by different types of risk ratings.

Comparison of Rating Methods by Disaster Indicators (사회재난 지표별 등급화 기법 비교: 가축질병을 중심으로)

  • Lee, Hyo Jin;Yun, Hong Sic;Han, Hak
    • Journal of the Society of Disaster Information
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    • v.17 no.2
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    • pp.319-328
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    • 2021
  • Purpose: Recently, a large social disaster has called for the need to diagnose social disaster safety, and the Ministry of Public Administration and Security calculates and publishes regional safety ratings such as regional safety index and national safety diagnosis every year. The existing safety diagnosis system uses equal intervals or normal distribution to grade risk maps in a uniform manner. Method: However, the equidistant technique can objectively analyze risk ratings, but there is a limit to classifying risk ratings when the distribution is skewed to one side, and the z-score technique has a problem of losing credibility if the population does not follow a normal distribution. Because the distribution of statistical data varies from indicator to indicator, the most appropriate rating should be applied for each data distribution. Result: Therefore, in this paper, we analyze the data of disaster indicators and present a comparison and suitable method for traditional equidistant and natural brake techniques to proceed with optimized grading for each indicator. Conclusion: As a result, three of the six new indicators were applied differently from conventional grading techniques

A Study on the Development of Long-term Self Powered Underground Pipeline Remote Monitoring System (자가 발전형 장기 지하매설배관 원격감시 장치 개발에 관한 연구)

  • Kim, Youngsear;Chae, Hyun-Byung;Seo, Jae-Soon;Chae, Soo-Kwon
    • Journal of the Korean Society for Environmental Technology
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    • v.19 no.6
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    • pp.576-585
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    • 2018
  • Systematic management during the whole life cycle from construction to operation and maintenance is very important for the seven underground pipelines (waterworks, sewerage, electricity, telecommunications, gas, heating, oil including waterworks and sewerage). Especially, it is the construction process that affects the whole life cycle of underground buried pipeline. In order to construct a new city or to maintain different underground pipes, it is always necessary to dig the ground and carry out construction and related work. There is a possibility that secondary and tertiary breaks frequently occur in the pipeline construction process after the piping constructed first in this process. To solve this problem, a system is needed which can monitor damage in real time. However, the supply of electric power for continuous operation of the system is limited according to the environment of underground buried pipelines, so it is necessary to develop a stable electric power supply system using natural energy rather than existing electric power. In this study, we developed a system that can operate the pipeline monitoring system for long time (24 hours and 15 days) using natural energy using wind and solar light.

Analysis on Ground Temperature Arrangement Function of Jinan Macho Village Grove (진안 하초 마을숲의 온도 조절 기능 분석)

  • Park, Jae-Chul;Jung, Gyung-Suk;Jang, Hei-Hwa
    • Journal of Korean Society of Rural Planning
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    • v.9 no.4 s.21
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    • pp.35-41
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    • 2003
  • The purpose of this study is on identifying the function of ground temperature arrangement of village grove. Case study was accomplished at Hacho village grove in Jinan-gun, Jeonbuk province. Hacho village grove was the largest grove of all and most formal grove in Jinan region. So ground temperature of outside and inside of Hacho village grove were measured from March to October in 2001. And comparative review about difference between outside and inside of village grove was accomplished. Our ancestors, in spite of orient and occident, have made a settlement in consideration of climatic conditions. We have to team from past pattern and add modern scientific technology. So traditional wisdom and wise planning process must be considered in order to create qualitative residential environment in present through natural elements. It is identified that in winter, the inner side ground temperature is higher than outside one of that and in summer, in contrary, the inner side one of that is lower than outside one of that. So it is identified that Macho village grove breaks winds and reduce the heating energy in winter, it reduces ground temperature and reduces cooling energy very well in summer. It is identified that village grove reduce ground temperature in summer better than any other season. It is identified that in summer, the effect of maintaining constant temperature is also better than my other season. So it is identified that village grove stabilize most changeable outside temperature in inside of that.

Synthesis of Vegetable Oil-Based Poly(β-amino ester) (식물성 오일 기반 Poly(β-amino ester) 합성)

  • Jang, Na-Ri;Kim, Beom Soo
    • Korean Chemical Engineering Research
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    • v.50 no.6
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    • pp.1064-1067
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    • 2012
  • Recently, there is a growing interest in vegetable oils, cheap and abundant renewable natural resources. Vegetable oils can be used as raw materials for ecofriendly biodegradable polymer materials. In this study, poly(${\beta}$-amino esters) were synthesized by polymerization reaction of acrylated epoxidized soybean oil (AESO) and 2-aminoethanol. Various polymer films were prepared by changing the molar ratio of AESO to 2-aminoethanol. The formation of C-N bonds in poly(${\beta}$-amino ester) was confirmed using FT-IR. Gel contents higher than 98% confirmed the synthesis of crosslinked polymer networks. Tensile strengths and elongation at breaks of polymer films ranged from 0.3 to 1.3 MPa and 32 to 55%, respectively. Polymer films degraded 2 to 7% of the initial weight in 35 days in phosphate buffer solution (pH 7.2) containing lipase enzyme.

A Study on Aesthetic Characteristics of Enlargement Hair Type - Compare the Enlarged Hair Type in the late Chosun Dynasty and that in Rococo - (확대형 두발양식의 미적특성에 관한 연구 - 조선후기와 로코코시대의 비교분석 -)

  • Yim, Lynn;Kim, Eun-Jung
    • Journal of the Korean Society of Costume
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    • v.57 no.4 s.113
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    • pp.143-158
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    • 2007
  • This study considers enlargement phenomenon in hair style as one of Costume types and analyzes its artistic characteristics based on the comparison between Hair style in the late Chosun Dynasty and that of the Rococo. First, its formative property, one of the common aesthetic characteristics, breaks the concept of traditional balance in Clothing and emphasizes its transformation, changes, and space beauty. This formative property shows the Enlargement and exaggeration beyond the concept of Space. Its sensuous property reflects women's psychological minds; exaggeration and sensualism. Artistic property doesn't focus on hair style only or clothing style only and considers hair style as renter of beauty as well as its important element. It shows the traditional beauty of nature and creativity in the Chosun Dynasty. Second, its formative property, one of the differential aesthetic characteristics, shows these following differences considering the aesthetic characteristics in the late Chosun Dynasty and that of the Rococo; mutual transformation, independent transformation, focus on distortion, harmony in scale, disharmony between irregularity and exception, extension and separation in space, etc. Sensuous property shows the temperate beauty and metaphorical sense, affected by the Practical Science, in the late Chosun Dynasty while it shows the secular sense and exaggerated beauty, affected by the Enlightenment, in the Rococo. Artistic property shows the harmony with the Clothing style, balanced wearing lines, and natural beauty, as one part of Clothing, in the late Chosun Dynasty. However it shows creativity, as separate part from Clothing, in the Rococo.