• Title/Summary/Keyword: NU

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한국어판 간호 섬망 선별 도구 개발 및 검증 (Development and validation of the Korean Nursing Delirium Scale)

  • 김경남;김철호;김광일;유현정;박시영;박연환
    • 대한간호학회지
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    • 제42권3호
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    • pp.414-423
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    • 2012
  • Purpose: The aims of this study were to develop and test the validity of the Korean Nursing Delirium Scale (Nu-DESC) for older patients in hospital. Methods: The Korean Nu-DESC was developed based on the Nu-DESC (Gaudreau, 2005), and revised according to nursing records related to signs and symptoms of older patients with delirium (n=361) and the results of a pilot study (n=42) in one general hospital. To test the validity of the Korean Nu-DESC, 75 older patients whom nurses suspected of delirium from 731 older patients from 12 nursing units were assessed by bedside nurses using the Korean Nu-DESC. A Receiver Operating Characteristic Curve of the Korean Nu-DESC was constructed with an accompanying Area Under the Curve (AUC). Results: Specific examples such as irritable, kidding, sleeping tendency, which were observed by bedside nurses in Korea, were identified in the five features of signs and symptoms of delirium in the instrument. The Korean Nu-DESC was psycho-metrically valid and had a sensitivity and specificity of .81-.76 and .97-.73, respectively. The AUC were .89, .74. Conclusion: Results of this study indicate that the Korean Nu-DESC is well-suited for widespread clinical use in busy inpatients settings and shows promise as a research instrument.

Functional Analyses of Centrosomal Proteins, Nek2 and NuMA in Development of Mouse Gametes and Early Embryos

  • Youn, Hong-Hee;Oh, Hwa-Soon;Lee, Kwang-Hee;Son, Chae-Ick;Lee, Sang-Ho
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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    • pp.96-96
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    • 2003
  • Nek2 (NIMA-related protein) is a mammalian cell cycle-regulated kinase that involves in chromosome condensation and centrosome regulation and NuMA (nuclear mitotic apparatus protein) is involved in spindle assembly during a cell cycle. The cellular distribution and organization of the centrosomal components is completely unknown during fertilization and embryonic development. We examined distribution of two well-known centrosomal proteins, Nek2 and NuMA in mouse gametes and embryos to get an insight in the reorganization of centrosomal proteins during germ cell development and early fertilization. Spermatogenic cells, gametes, and embryos were analyzed with anti-Nek2 or -NuMA antibodies by immunological assay, RT-PCR, and overexpression through gene transfection. Mitotically or meiotically active spermatogenic cells were intensively stained with these antibodies in both centrosomes and cytoplasm, whereas the oocytes showed different staining patterns depending on the meiotic stages. During maturation, GV, GVBD, and MI stage were clearly stained with NuMA antibody in the nucleus or cytoplasm at MII. Also, Nek2 was detectable in cytoplasm as scattered spots or chromosome associated at MII. In early developmental embryo, NuMA was detected in nucleus of each blastomere, while Nek2 was detected in cytoplasm. In contrast to previously reported results, Nek2 and NuMA were detected in both decondensing head, and the centriole of demembranated and decondensed sperm or whole body of trypsin-treated sperm for Nek2. During meiotic progress in oocytes, transcripts levels were the highest in MI stage and then downregulated in MII. Also, it shows dramatically change in early developmental embryos, firstly, it was increased until 4 cell stage and reduced in 8 cell stage, and finally, transcript levels were upregulated until blastoscyst. This finding suggests that cnetrosomal component may play an important role in reorganizing of functional centrosome during fertilization process and subsequent development.

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A Study on an Analysis and Design of the Internal Structure of Heumgyeonggak-nu

  • Kim, Sang Hyuk;Yun, Yong-Hyun;Ham, Seon Young;Mihn, Byeong-Hee;Ki, Ho-Chul;Yoon, Myung-Kyoon
    • Journal of Astronomy and Space Sciences
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    • 제34권2호
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    • pp.171-182
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    • 2017
  • In this study, the internal structure of a Heumgyeonggak-nu (欽敬閣漏) was designed, and the power transmission mechanism was analyzed. Heumgyeonggak-nu is an automated water clock from the Joseon Dynasty that was installed within Heumgyeonggak (欽敬閣), and it was manufactured in the $20^{th}$ year of the reign of King Sejong (1438). As descriptions of Heumgyeonggak-nu in ancient literature have mostly focused on its external shape, the study of its internal mechanism has been difficult. A detailed analysis of the literature record on Heumgyeonggak-nu (e.g., The Annals of the Joseon Dynasty) indicates that Heumgyeonggak-nu had a three-stage water clock, included a waterfall or tilting vessel (欹器) using the overflowed water, and displayed the time using a ball. In this study, the Cheonhyeong apparatus, water wheel, scoop, and various mechanism wheels were designed so that 16 fixed-type scoops could operate at a constant speed for the water wheel with a diameter of 100 cm. As the scoop can contain 1.25 l of water and the water wheel rotates 61 times a day, a total of 1,220 l of water is required. Also, the power gear wheel was designed as a 366-tooth gear, which supported the operation of the time signal gear wheel. To implement the movement of stars on the celestial sphere, the rotation ratio of the celestial gear wheel to the diurnal motion gear ring was set to 366:365. In addition, to operate the sun movement apparatus on the ecliptic, a gear device was installed on the South Pole axis. It is expected that the results of this study can be used for the manufacture and restoration of the operation model of Heumgyeonggak-nu.

유리섬유시트로 보강된 RC 보의 휨 거동에 관한 연구 (Flexural Behaviors of Reinforced Concrete Beams Strengthened with Glass Fiber Sheets)

  • 김성도;조백순;성진욱
    • 한국철도학회논문집
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    • 제12권3호
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    • pp.388-395
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    • 2009
  • 유리섬유시트로 보강된 철근콘크리트 보의 휨 거동을 조사하기 위해, 하나의 기준보와 8개의 보강보(4개의 NU-보강보, 4개의 U-보강보)에 대한 보강보 휨 실험을 수행하였다. NU 보강보는 단부에 U 밴드를 적용하지 않은 보를, U-보강보는 U 밴드를 가진 보를 의미한다. 보강보 실험에서의 실험변수들은 유리섬유시트의 보강 양, U 밴드의 유무 등이 있다. 기준보와 비교하여 NU 보강보와 U 보강보의 최대하중은 각각 48%와 34% 증가하였으며, 휨 강성은 각각 920%와 880% 증가하였다. NU 보강보와 U 보강보에 대한 연성지수는 1.43에서 2.60 사이에 놓여있다. U 밴드를 가진 보강 시스템은 섬유시트의 계면박리 파괴를 지연시키고, U 밴드가 없는 보강시스템보다 나은 연성거동을 나타내 보였다. NU 보강보와 U 보강보 모두에서 섬유시트 겹수의 증가에 따라 최대하중과 휨 강성은 증가하였다. 실험결과들을 이론적인 비선형 휨 해석결과와 비교하였으며, 잘 일치함을 확인하였다.

On (H, μn) Summability of Fourier Series

  • CHANDRA, SATISH
    • Kyungpook Mathematical Journal
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    • 제43권4호
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    • pp.513-518
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    • 2003
  • In this paper, we have proved a theorem on Hausdorff summability of Fourier series which generalizes various known results. We prove that if $${\int}_{o}^{t}\;{\mid}{\phi}(u){\mid}\;du=o(t)\;as\;t{\rightarrow}0\; and\;\lim_{n{\rightarrow}{\infty}}{\int}^{\eta}_{{\pi}/n}{\frac{{\mid}{\phi}(t)-{\phi}(t+{\pi}/n){\mid}}{t}}dt=o(n)$$ where 0 < ${\eta}$ < 1, then the Fourier series is (H, ${\mu}_n$) summable to s at t = x where the sequence ${\mu}_n$ is given by ${\mu}_n={\int}^1_0x^n{\chi}(x)\;dx\;n=0,1,2\;and\;K_n(t)=\limits\sum_{{\nu}=0}^n(\array {n\\{\nu}})({\Delta}^{{n}-{\nu}}{\mu}_{\nu}){\frac{sin{\nu}t}{t}}$.

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The CCP Assessment of CANDU-6 Channel Loaded with CANFLEX-NU Fuel Bundle

  • Jun, Ji-Su;Park, Joo-Hwan;Suk, Ho-Chun
    • 한국원자력학회:학술대회논문집
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    • 한국원자력학회 1997년도 춘계학술발표회논문집(1)
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    • pp.374-379
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    • 1997
  • The thermal margin of CANDU-6 reactor is estimated by the CCP, which is dependent on fuel channel hydraulics and the CHF of fuel bundle. This paper intents to describe the characteristics of CCP behavior for the CANDU-6 channel in which CANFLEX-NU fuel bundles are assumed to be loaded. Also, it includes the thermal margin evaluation of the CANDU-6 channel loaded with a mixed CANFLEX-NU and 37-element fuel bundles as a simulation of the partial loading of CANFLEX-NU fuel bundle in the CANDU-6 reactor. For the mixed fuel channels, the effects of axial flux distribution(AFD) on CCP were investigated by using the AFD tilted in the downstream. The CCP of CANFLEX-NU fuel bundle was found to be improved by the CHF enhancement, despite of the slight flow decrease, in case of both full and partial loading, compared with those of a standard 37-element fuel bundle.

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Ab Initio Studies of Hydrogen Bihalide Anions: Anharmonic Frequencies and Hydrogen-Bond Energies

  • Cheong, Byeong-Seo
    • 대한화학회지
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    • 제63권4호
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    • pp.237-245
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    • 2019
  • Hydrogen bihalide anions, $XHX^-$ (X = F, Cl, and Br) have been studied by high level ab initio methods to determine the molecular structure, vibrational frequencies, and energetics of the anions. All bihalide anions are found to be of linear and symmetric structures, and the calculated bond lengths are consistent with experimental data. The harmonic frequencies exhibit large deviations from the experimental frequencies, suggesting the vibrations of these anions are very anharmonic. Two different approaches, the VSCF and VPT2 methods, are employed to calculate the anharmonic frequencies, and the results are compared with the experimental frequencies. While the ${\nu}_1$ and ${\nu}_2$ frequencies are in reasonable agreement with the experimental values, the ${\nu}_3$ and ${\nu}_1+{\nu}_3$ frequencies still exhibit large deviations. The hydrogen-bond energies and enthalpies are calculated at various levels including the W1BD and G4 composite methods. The hydrogen-bond enthalpies calculated are in good agreement with the experimental values.

Rapid Detection of Ovarian Cancer from Immunized Serum Using a Quartz Crystal Microbalance Immunosensor

  • Chen, Yan;Huang, Xian-He;Shi, Hua-Shan;Mu, Bo;Lv, Qun
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권7호
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    • pp.3423-3426
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    • 2012
  • Background: The objective of this study was to measure the antibody content of NuTu-19 ovarian cancer cells in serum samples using a quartz crystal microbalance (QCM) immunosensor. Materials and Methods: NuTu-19 cells were first cultured onto the electrode surfaces of crystals in Dulbecco's modified Eagle medium, and then specified amounts of immunized serum samples of immunized rabbit were also added. The change in mass caused by specific adsorbtion of antibodies of NuTu-19 to the surfaces of the crystals was detected. Results: The change in resonance frequency of crystals caused by immobilization of NuTu-19 cells was from 83 to 429Hz. The antibody content of NuTu-19 detected was 341ng/ul. The frequency shifts were linearly dependent on the amount of antibody mass in the range of 69 to 340ng. The positive detection rate and the negative detection rate were 80% and 100%, respectively. Conclusion: This immunoassay provides a viable alternative to other early ovarian cancer detection methods and is particularly suited for health screening of the general population.

Interpretation of coefficient of consolidation from CRS test results

  • Jia, Rui;Chai, Jinchun;Hino, Takenori
    • Geomechanics and Engineering
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    • 제5권1호
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    • pp.57-70
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    • 2013
  • Constant rate of strain (CRS) consolidation tests were conducted for undisturbed Ariake clay samples from three boreholes in Saga Plain of Kyushu Island, Japan. The coefficients of consolidation ($c_{\nu}$) were interpreted from the CRS test results by small- and large-strain theory. Large-strain theory was found to interpret smaller $c_{\nu}$ values and less strain rate effect on $c_{\nu}$ than that by small-strain theory. Comparing the theoretical strain distributions within a soil specimen to those obtained by numerical simulation shows that the small-strain theory can be used only for the dimensionless parameter $c_{\nu}/\dot{\varepsilon}H_0^2{\geq}50$ (where $\dot{\varepsilon}$ is strain rate and $H_0$ is the specimen height), and the large-strain theory can be used for a larger range of strain rates. Applying the criterion to undisturbed Ariake clay with a $c_{\nu}$ value of about $1{\times}10^{-7}\;m^2/s$, it is suggested that the large-strain theory should be adopted for calculating the $c_{\nu}$ value when $\dot{\varepsilon}$ > 0.03%/min.