• Title/Summary/Keyword: NSA9

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Test for Resource Service by the User Web Portal and the NSI based Network Resource Service Agent (사용자 웹 포털과 NSI 기반의 네트워크 자원 서비스 에이전트에 의한 자원서비스 시험)

  • Lim, Huhnkuk
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37B no.9
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    • pp.822-830
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    • 2012
  • The most representative research network in Korea, KREONET has developed the NSI based NSA (Network Service Agent) technology. The developed NSA supports web service and provides services for reservation, provision, release and termination of network resource, whenever users want to utilize them. In this paper, the system blocks of the developed NSA and flows of NSI interface massage are presented firstly, Also, service test results for NSI connection reservation is given through internet communication of the web portal system to operate as the RA NSA and the NSA, Finally, it is confirmed that reservation, provision, release and termination of network resource can be established through NSI messages based on reservation information from user, between the web portal and the NSA.

NSA9, a human prothrombin kringle-2-derived peptide, acts as an inhibitor of kringle-2-induced activation in EOC2 microglia

  • Kim, Ji-Yeon;Kim, Tae-Hyong;Kim, Soung-Soo
    • BMB Reports
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    • v.42 no.6
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    • pp.380-386
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    • 2009
  • In neurodegenerative diseases, such as Alzheimer' and Parkinson', microglial cell activation is thought to contribute to CNS injury by producing neurotoxic compounds. Prothrombin and kringle-2 increase levels of NO and the mRNA expression of iNOS, IL-1$\beta$, and TNF-$\alpha$ in microglial cells. In contrast, the human prothrombin kringle-2 derived peptide NSA9 inhibits NO release and the production of pro-inflammatory cytokines such as IL-1$\beta$, TNF-$\alpha$, and IL-6 in LPS-activated EOC2 microglia. In this study, we investigated the anti-inflammatory effects of NSA9 in human prothrombin- and kringle-2-stimulated EOC2 microglia. Treatment with 20-100 ${\mu}M$ of NSA9 attenuated both prothrombin- and kringle-2-induced microglial activation. NO production induced by MAPKs and NF-$\kappa$B was similarly reduced by inhibitors of ERK (PD98059), p38 (SB203580), NF-$\kappa$B (N-acetylcysteine), and NSA9. These results suggest that NSA9 acts independently as an inhibitor of microglial activation and that its effects in EOC2 microglia are not influenced by the presence of kringle-2.

Translation and Validation of the Korean Version Revised Nottingham Sensory Assessment (한국판 수정된 노팅엄 감각평가의 신뢰도 타당도 연구)

  • Ji, Eun-Kyu;Lee, Sang-Heon
    • The Journal of the Korea Contents Association
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    • v.20 no.9
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    • pp.511-519
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    • 2020
  • The aim of this study was to translate and validate the revised Nottingham Sensory Assessment(rNSA) in Republic of Korea. A cross-sectional study was conducted to translate the rNSA into Korean using a modified forward/backward translation procedure. Inter-rater and intra-rater reliability, internal consistency, and concurrent validity were investigated to validate the Korean version rNSA. The Korean version rNSA showed excellent inter-rater reliability (r=0.92-1.00) and intra-rater reliability (r=0.93-1.00). Significant correlations were found between sensory assessment results of the Korean version of the rNSA and the Korean Fugl Meyer Assessment Sensory subscales (r=0.96). The Cronbach α value of internal consistency of Korean version rNSA was ranged from 0.73 to 0.90, the value of K-FMA-S was ranged from 0.70 to 0.88. In these results, psychometric properties of the Korean version of the rNSA achieved the standard level and can be feasible in clinical practice to assess sensory function following stroke in Republic of Korea.

Functional Properties and Antioxidant Effects of Solanum nigrum-Ethanol Extract (까마중-에탄올 추출물의 기능적 특성과 항산화 효과)

  • Jeong, Kap-Seop;Lee, Nahm-Gull
    • Journal of Environmental Science International
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    • v.18 no.11
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    • pp.1207-1214
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    • 2009
  • Functional properties of Solanium nigrum-ethanol extract were investigated, nitrite scavenging ability(NSA) and antioxidant activities based on thiobarbituric acid(TBA) value were measured. The contents of potassium in fruit and root, calcium in leaf were the highest mineral components in each parts of Solanium nigrum. Total aromatics contents(TAC) was order of fruit>root>leaf, total flavonoid contents(TFC) in leaf was 6 and 10 times, total phenolic compounds contents(TPC) in leaf was 15 and 30 times of those in fruit and root, respectively, and TFC was high with TPC increase. NSA of leaf-ethanol extract was 61.9% on pH 1.2, 53.5% on pH 3.0, 54.8% on pH 4.0 and 14.3% on pH 6.0, where as NSA of root and fruit-ethanol were considerably low to 3.5~7.9% over pH 1.2~6.0. TBA value of soybean oil with the dosage of leaf-extract showed few differences from control within 3 days, but it fairly decreased with considerable antioxidant effect to 47.6% of the control in 8 days.

Evaluation of Antioxidant and Nitrite Scavenging Activity of Seaweed Extracts (해조류 추출물의 항산화 및 nitrite 소거활성 평가)

  • Ahn, Seon-Mi;Hong, Yong-Ki;Kwon, Gi-Seok;Sohn, Ho-Yong
    • Journal of Life Science
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    • v.21 no.4
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    • pp.576-583
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    • 2011
  • In the course of study for the development of functional food ingredients from seaweeds having useful biological activities, the in-vitro antioxidant and nitrite scavenging activities of the methanol extracts prepared from 35 different seaweeds (17 phaeophyta, 11 rhodophyta and 7 chlorophyta) were determined. At $500\;{\mu}g/ml$ concentration of the methanol extracts, Ecklonia cava, Ecklonia stolonifera, Eisenia bicyclis (Kjellman) Setchell, Ishige foliacea, I. okamurai, Sargassum confusum, S. fulvellum, S. yamade and Zostera marina showed 60% more DPPH and ABTS scavenging activity. The exceptions were found in I. okamurai and Z. marina, which showed 45% and 53% ABTS scavenging activity, respectively. The correlation coefficient between DPPH and ABTS scavenging activities was 0.855, suggesting that the 9 different seaweeds extracts could scavenge anion and cation radicals concurrently. In reducing power, only E.cava, E.stolonifera and E.bicyclis showed above 0.88 ($Abs_{700}$). In a while, in nitrite scavenging activity at $100\;{\mu}g/ml$ concentration of the methanol extracts, 19 different seaweeds extracts including I. foliacea, I. okamurai, S. confusum, S. fulvellum, and S. yamade showed 60% more activity. Calculation of $IC_{50}s$ of DPPH, ABTS and nitrite scavenging activities of 9 different seaweeds extracts further showed that I. foliacea and S. yamade, besides E.cava, E.stolonifera and E.bicyclis, have strong antioxidant and nitrite scavenging activity. These results suggest that the selected 9 different seaweeds could be developed as functional food ingredients and I. foliacea and S. yamade have potential as novel natural sources of antioxidant and nitrite scavenger.

Antioxidative and Nitrite Scavenging Activities of Mugwort and Pine Needle Extracts (쑥과 솔잎의 항산화작용 및 아질산염 소거작용)

  • 박찬성;권충정;최미애;박금순;최경호
    • Food Science and Preservation
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    • v.9 no.2
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    • pp.248-252
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    • 2002
  • Mugwort and pine needle were extracted with water and 70% ethanol. Electron donating ability(EDA) of extracts were ranged from 50% to 57% in mugwort water extract(MGW) and ranged from 51% to 64% in mugwort ethanol extract(MGE) at 300-1,000ppm. EDA of extracts were ranged from 52% to 60% in pine needle water extract(PNW) and ranged from 68% 71% in pine needle ethanol extract(PNE) at 100-500ppm. EDA of PNW was 70% and that of PNE was 77% at 1,00(ppm. Nitrite scavenging ability(NSA) of extracts measured at various pH(1.2, 3.0, 4.2, 6.0) was the highest in all extracts at pH 1.2 and decreased with increasing pH, suggesting it is pH dependent. NSA of mugwort extracts at 1,000ppm, water extract was 37% and ethanol extract was 27% at pH 1.2. NSA of pine needle extracts at 1,000ppm, water extract was 65%and ethanol extract was 53% at pH 1.2. EDA and NSA of pine needle extracts were higher than mugwort in both of water and ethanol extract. EDA of ethanol extracts were higher than water extracts while NSA of water extracts were higher than ethanol extracts in both of mugwort and pine needle.

Functional Properties of Brassica oleracea L- Extracts and Quality Characteristics of Korean Wheat Noodles With Brassica oleracea L. (적채 추출물의 기능성 및 적채를 첨가한 우리밀 국수의 품질특성)

  • Kim, Mi-Lim
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.9
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    • pp.1443-1449
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    • 2005
  • Quality characteristics and functional properties of Korean wheat noodle with brassica oleracea L. powder were investigated to develop health promoting and high quality product. Brassica oleracea L. powder was extracted with water and $70\%$ ethanol, and the extracts were tested its electron donating ability (EDA) and nitrite scavenging ability (NSA). Quality characteristics of the noodle were evaluated by its color, flavor, moisture, softness, texture and taste evaluation. Microbiological Quality was also tested counting total viable cells. EDA was highest at 1000 ppm of both water extract ($64\%$ of EDA) and ethanol extract ($76\%$ of EDA). NSA was highest pH 1.2 of both water extract ($42\%$ of NSA) and ethanol extract ($46\%$ of NSA). In antimicrobial activity test, Korean wheat noodle with $3\%$ pine pollen powder displayed $0.5{\~}1$ log cycle of total viable cell counts lower than that of control at 5 days of storage. Sensory evaluation of Korean wheat dried and cooked noodles with $3\%$ Brassica oleracea L. powder showed significantly higher scores in overall.

Antioxidative and Nitrite Scavenging Activities of Cordyceps militaris Extracts (동충하초의 항산화작용 및 아질산염 소거작용)

  • 박찬성;권충정;최미애;박금순;최경호
    • Food Science and Preservation
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    • v.9 no.1
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    • pp.109-113
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    • 2002
  • The purpose of this study was to investigate antioxidative and nitrite scavenging activities of extracts of Cordyceps militaris. Fruiting body and mycelia of artificially cultivated Cordyceps militaris were extracted with water and 70% ethanol. In Cordyceps militaris mycelia, electron donating ability (EDA) of water extract ranged from 37% to 47% and ethanol extract ranged from 57% to 70% at 300∼1,000 ppm. In Cordyceps militaris fruiting body, EDA of water extract and ethanol extract were similar, ranged from 19% to 48% at 300-1,000 ppm. Nitrite scavenging ability (NSA) of extracts measured at various pH (1.2, 3.0, 4.2, 6.0) was the highest at pH 1.2 and decreased with increasing pH, suggesting it is pH dependent. In Cordyceps militaris mycelia, NSA of water extract 1,000 ppm was 23% and that of ethanol extract 1,000 ppm was 37% at pH 17. In Cordyceps militaris fruiting body, NSA of water extract 1,000 ppd was 12% and that of ethanol extract 1,000 ppm was 37% at pH 1.2. EDA and NSA of Cordyceps milituis were higher in extract of mycelia than fruiting beds and higher in ethanol extract than water extract of each part.

효율적 국방망 구축을 위한 MISSI 분석

  • 송유진
    • Review of KIISC
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    • v.9 no.2
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    • pp.3-16
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    • 1999
  • 본 고에서는 국방부의 현대적 전쟁환경에 맞는 새로운 정보시스템을 구축하여 폭넓 은 정보교환과 효율적인 정보관리 능력을 증강하기 위하여 행정, 교육, 금융, 공안, 외교 및 물류 등의 독립적인 전용 전산망을 통합된 하나의 전산망으로 구축할 경우 다중등급보안을 처리하기 위해 미국 NSA가 주도하여 수행하고 있는 MISSI와 이에 이용되는 Fortezza 그리 고 현재 미국에서 구축중에 있는 DII의 구성에 대해 분석하였다. 본 고는 향후 정보전을 대 비한 효율적인 국방망 구축을 위한 기초자료이다.

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Mixed Carbon/Polypyrrole Electrodes Doped with 2-Naphthalenesulfonic Acid for Supercapacitor (2-Naphthalenesulfonic Acid로 도핑된 혼합카본/폴리피롤을 이용한 Supercapacitor용 전극)

  • Jang, In-Young;Kang, An-Soo
    • Korean Chemical Engineering Research
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    • v.43 no.3
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    • pp.425-431
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    • 2005
  • New type of supercapacitor using high surface area activated carbons mixed with high conductivity polypyrrole (Ppy) has been prepared in order to achieve low impedance and high energy density. Mixed carbons of BP-20 and MSP-20 were used as the active electrode material, and polypyrrole doped with 2-naphthalenesulfonic acid (2-NSA) and carbon black (Super P) as conducting agents were added to activated carbons in order to enhance good electric conductivity. Electrodes prepared with the activated electrode materials and the conducting agents were added to a solution of organic binder [P(VdF-co-HFP) / NMP]. The ratio of optimum electrode composition was 78 : 17 : 5 wt.% of (MSP20 : BP-20=1 : 1), (Super P : Ppy=10 : 7) and P(VdF-co-HFP) respectively. The performance of unit cell with addition of 7 wt% Ppy have shown specific capacitance of 28.02 F/g, DC-ESR of $1.34{\Omega}$, AC-ESR of $0.36{\Omega}$, specific energy of 19.87 Wh/kg and specific power of 9.77 kW/kg. With addition of Ppy, quick charge-discharge of unit cell was possible because of low ESR, low charge transfer resistance and quick reaction rate. And good stability up to 500 chargedischarge cycles were retained about 80% of their original capacity. It was concluded that the specific capacitance originated highly from compound phenomena of the pseudocapacitance by oxidation-reduction of polypyrrole and the nonfaradaic capacitance by adsorption-desorption of activated carbons.