• 한국패류학회지
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• 제29권3호
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• pp.171-179
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• 2013

동양달팽이의 arginine kinase 유전자는 염기서열 1065개로 이루어져있으며 355개의 아미노산으로 이루어져 있으며, BLAST 결과를 토대로 유사도가 높은 25개의 참고 서열과 동양달팽이의 arginine kinase의 아미노산 서열을 MEGA5 프로그램의 clustalW 모듈을 이용하여 multiple sequence alignment 를 수행한 결과, 연체동물문에 속하는 복족강 (5종), 두족강 (5종), 이매패강 (4종) 등에 속하는 생물들이 같은 군으로 묶였으며, 절지동물문 곤충강 에 속하는 나비목 (2종), 벌목 (1종), 노린재목 (2종) 등에 속하는 생물들이 같은 군으로 묶이고, 갑각강 (5종), 거미강 (1종) 에 속하는 생물들이 묶이는 것을 알 수 있었다. Psipred 소프트웨어를 통해 2D 구조를 비교 분석한 결과도 multiple align 및 phylodendrogram 결과와 밀접한 관계가 있음을 알 수 있었다. 시간에 따른 arginine kinase의 발현양상을 확인한 결과 control에 비하여 6시간에서 약 1.2배 정도 발현이 증가하는 것을 확인할 수 있었으며, 12시간이 지나면 점차 감소하는 것을 확인할 수 있었다. EST를 통해 밝혀진 N. samarangae 의 Ark 서열은 근연종들의 서열과 일치함을 알 수 있었으며, 본 연구 결과를 통해 무척추동물에서의 선천성 면역 관련 유전자 연구에 동양달팽이가 좋은 모델이 될 수 있음을 제시하고 있다.

• 센서학회지
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• 제16권5호
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• pp.337-341
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• 2007

$CsSrCl_{3}$ crystal was grown using Czochralski method from equimolar mixture of CsCl and $SrCl_{2}$. The spectrum range of the luminescence excited by 205 nm of wavelength was about $280{\sim}550$ nm, and its peak emission appeared at 343 nm. The luminescence decay curve of the $CsSrCl_{3}$ revealed two exponential components with time constants of 60 ns and 700 ns. The energy resolution for $^{137}Cs$ 662 keV ${\gamma}$-ray was 10.3 %. The pulse shape was linear at high energy, but some deviation existed in the low energy region.

• International Journal of Control, Automation, and Systems
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• 제2권3호
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• pp.279-288
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• 2004

This paper presents a novel design for a tubular linear brushless permanent-magnet motor. In this design, the magnets in the moving part are oriented in an NS-NS―SN-SN fashion which leads to higher magnetic force near the like-pole region. An analytical methodology to calculate the motor force and to size the actuator was developed. The linear motor is operated in conjunction with a position sensor, three power amplifiers, and a controller to form a complete solution for controlled precision actuation. Real-time digital controllers enhanced the dynamic performance of the motor, and gain scheduling reduced the effects of a nonlinear dead band. In its current state, the motor has a rise time of 30 ms, a settling time of 60 ms, and 25% overshoot to a 5-mm step command. The motor has a maximum speed of 1.5 m/s and acceleration up to 10 g. It has a 10-cm travel range and 26-N maximum pull-out force. The compact size of the motor suggests it could be used in robotic applications requiring moderate force and precision, such as robotic-gripper positioning or actuation. The moving part of the motor can extend significantly beyond its fixed support base. This reaching ability makes it useful in applications requiring a small, direct-drive actuator, which is required to extend into a spatially constrained environment.

• The Korean Journal of Pain
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• 제25권2호
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• pp.89-93
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• 2012

Background: Hemorrhoid is one of the most common surgical diseases occurring in the anorectal region. In this study, we evaluated the effect of ischiorectal fossa block on alleviating post hemorrhoidectomy pain. Methods: In this study, 90 patients suffering from hemorrhoids were evaluated. They were randomly divided into 3 groups. The first group had no block, the second group an ischiorectal block with placebo (normal saline), and the third group a preemptive ischiorectal block with bupivacaine. Postoperative variables such as pain intensity, pethidine consumption, nausea, and vomiting were compared between the groups. Results: The postoperative pain score in group 1 was $8.5{\pm}1.3$ and $8.1{\pm}0.9$ (P=NS) in group 2. The post operative analgesic demand was $3.1{\pm}1.5$ and $3.3{\pm}1.8$ hours in groups 1 and 2, respectively (P=NS). The post operative pain score and analgesic demand were $4.2{\pm}2.1$ and $9.3{\pm}2.7$ hours, respectively, in group 3 (P < 0.0001). Conclusions: Preemptive ischiorectal block reduces the posthemorrhoidectomy pain and opioid demand.

• 한국가금학회지
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• 제46권3호
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• pp.173-183
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• 2019

조류인플루엔자 바이러스 H7 subtype에 속하는 바이러스 중 일부는 가금류에 감염할 경우 고병원성이 발휘된다. 또 H7 아형 AIV중 일부는 사람에 감염하여 사망 등을 유발할 수도 있다. 본 연구는 야생조류로부터 분리된 H7 아형 조류인플루엔자 바이러스 6주(H7N7 아형 4주, H7N1 아형 2주)를 대상으로 8개 유전자 분절 전체의 염기서열을 분석하여 병원성, 사람 감염 가능성 등 그 특성을 조사하였다. 계통유전학적 분석결과, 국내에서 분리된 H7 아형 분리주들은 8개 유전자(HA, NA, PB2, PB1, PA, NP, M, NS) 모두 Eurasian lineage로 분류되었으나, Eurasian lineage 내에서도 각기 다른 sublineage로 분류되어 유전적 다양성이 있는 것으로 분석되었다. 한국 분리주 6주는 HA 단백질 분절부위 아미노산은 두 종류(PEIPKGR 및 PELPKGR)의 motif를 가지고 있었으나, 모두 저병원성 바이러스 특성을 가지고 있었다. 숙주세포 결합 특이성과 관련 있는 HA 단백질 receptor-binding site를 분석한 결과, 한국 분리주 모두는 사람 세포 수용체 결합특이성보다는 조류 세포 수용체 결합 특이성을 가지는 것으로 나타났다. 사람 감염 가능성을 높게 하는 부위에서의 아미노산 치환(PB2 단백질의 E627K 및 PB1단백질의 I368V)도 나타나지 않았고, 또한 NA stalk region에서의 결손도 관찰되지 않았다. 이상의 결과를 미루어 볼 때 한국 야생조류에서 분리된 H7 아형 6주 모두는 저병원성 바이러스로 최근 중국에서 사람 감염이 나타나고 있는 H7N9 바이러스와는 유전적으로 다른 계열의 바이러스인 것으로 판단된다.

• 한국광학회지
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• 제6권3호
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• pp.201-213
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• 1995

전자빔여기 XeF$(C\rightarrowA$ 엑시며 레이저의 상준위 B-와 C-상태에 대하여 충동혼합 운동과정을 포함하는 모델을 컴퓨터 시뮬레이션하여 이의 출력특성을 해석하였다 $XeF^*(B)$ 의 수밀도에 관련되는 $XeF^*(C)$의 형성에 대하여 레이저 에너지를 실험치와 비교하였다. 이 결과는 70ns[FWHM]의 전자빔(800kV, 21kA)을 사용한 대기압 매질에서 매우 좋은 일치$(28.5 mJ\pm5%)$를 보였고, $Xe/F_2/Ar=5.26/0.49/94.28%$의 최적화된 가스혼합비를 확인하였다. 또한 시뮬레이션으로 $XeF^*(C)$의 형성경로, $XeF^*(C)$의 완화경로, 청록색 파장대역의 흡수경로에 대한 $F_2$ 할로겐 도우너 및 Xe 압력의 함수관계를 조사하였다.

• Restorative Dentistry and Endodontics
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• 제24권4호
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• pp.614-622
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• 1999

Recent studies have implicated that more rostral components of the trigeminal spinal nucleus including subnucleus oralis (Vo) in orofacial nociceptive mechanisms. Since there is only limited electrophysiological evidence, the present study was initiated to characterize the receptive field and response properties of malls nociceptive neurons in chloralose/urethan-anesthetized rats. Single neuronal activity was recorded in right subnucleus oralis, and types of nociceptive neurons classified wide dynamic range (WDR), NS (nociceptive specific) and deep nociceptive (D) and the mechanoreceptive field (RF) and response properties were determined. A total of 34 nociceptive neurons could be subdivided into 17WDR neurons, 12NS neurons and 5D neurons. Vo nociceptive neurons had RF involving maxillary and/or mandibular divisions mainly located in the intraoral and/or perioral regions. Majority of Vo nociceptive neurons showed spontaneous activity less than 1Hz. The NS and D neurons activated only by heavy pressure and/or pinch stimuli had high mechanical thresholds compared to WDR neurons activated also by tactile stimuli. Vo nociceptive neurons showed a progressive increase of response to the graded mechanical stimuli. 39% of Vo nociceptive neurons received C-fiber electrical input as well as A-fiber electrical input from their RF, and 45% of them responded to electrical stimulation of the right maxillary first molar. 41% of Vo nociceptive neurons responded to noxious heat applied to their RF, and 18% of them showed an immediate burst of discharges following MO application to the right maxillary first molar pulp. These results indicate that Vo is involved in the transmission of nociceptive information mainly coming from intraoral or perioral region including tooth pulp.

• Transactions on Electrical and Electronic Materials
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• 제7권1호
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• pp.7-11
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• 2006

The changes of the electrical conductivity in chalcogenide amorphous semiconductors, $Ge_{1}Se_{1}Te_{2}$, have been studied. A phase change random access memory (PRAM) device without an access transistor is successfully fabricated with the $Ge_{1}Se_{1}Te_{2}$-phase-change resistor, which has much higher electrical resistivity than $Ge_{2}Sb_{2}Te_{5}$ and its electric resistivity can be varied by the factor of $10^5$ times, relating with the degree of crystallization. 100 nm thick $Ge_{1}Se_{1}Te_{2}$ thin film was formed by vacuum deposition at $1.5{\times}10^{-5}$ Torr. The static mode switching (DC test) is tested for the $100\;{\mu}m-sized$ $Ge_{1}Se_{1}Te_{2}$ PRAM device. In the first sweep, the amorphous $Ge_{1}Se_{1}Te_{2}$ thin film showed a high resistance state at low voltage region. However, when it reached to the threshold voltage, $V_{th}$, the electrical resistance of device was drastically reduced through the formation of an electrically conducting path. The pulsed mode switching of the $20{\mu}m-sized$ $Ge_{1}Se_{1}Te_{2}$ PRAM device showed that the reset of device was done with a 80 ns-8.6 V pulse and the set of device was done with a 200 ns-4.3 V pulse.

• 한국전기전자재료학회논문지
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• 제14권5호
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• pp.417-422
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• 2001

The needs of new materials that substitute Si Oxide capacitor layer in high density DRAM increase. So in this paper, we choose the slim region 14/50/50 PLZT composition and fabricated thin films by PLD and estimated the characteristics for DRAM application. 14/50/50 PLZT thin films have crystallized into perovskite structure in the $600^{\circ}C$ deposition temperature and 200 mTorr Oxygen pressure. In this condition, PLZT thin films had 985 dielectric constant, storage charge density 8.17 $\mu$C/$\textrm{cm}^2$ and charging time 0.20ns. Leakage Current density was less than 10$^{-10}$ A/$\textrm{cm}^2$ until 5V bias voltage.

• 대한전자공학회논문지
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• 제23권6호
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• pp.741-746
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• 1986

A novel n-p-n bipolar transistor of which emitter is self-aligned with base contact by polyilicon is developed for using in high speed and high packing density LSI circuits. The emitter of this transistor is separated less than 0.4 \ulcorner with base contact by self-aligh technology, and the emitter feature size is less than 3x5 \ulcorner\ulcorner Because the active region of this transistor is not damaged through all the process, it has excellent electric properties. Using the n-p-n transistors by 3.0\ulcorner design rules, a NTL ring oscillator has 380 ps, a CML ring oscillator has 390ps, and a I\ulcorner ring oscillator has 5.6ns of per-gate minimum propagation delay time.