• Title/Summary/Keyword: Multiple events

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Signal Transduction of the Cytokine Receptor

  • Watanabe, Sumiko
    • Animal cells and systems
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    • v.2 no.2
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    • pp.153-164
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    • 1998
  • Cytokines regulate proliferation, differentiation and functions of haemotopoietic cells. Each cytokine possesses a variety of activities on various target cells (pleiotropy) and various cytokines have similar and overlapping activities on the same target cells (redundancy). The nature of these cytokine activities predicts unique feature of cytokine receptors, namely, cytokine has multiple receptors, different cytokines share a common receptor, and different cytokine receptors are linked to common signaling pathways. cDNA cloning of genes for cytokine receptors revealed distinct sets of receptor family with different structural features. The cytokine receptor superfamily consists of a largest family, and contains more than twenty cytokine receptor subunits. This receptor has common structural features in both extracellular and intracellular regions without tyrosine kinase domain. Another striking feature of the receptor is to share common subunit of multiple cytokines, which partly explains the redundancy of activities of some cytokines. Recent studies revealed detailed signaling events of the cytokine receptor, the primary activation of JAK and subsequent phosphorylation of tyrosine residues of receptor, and various cellular proteins. Many SH2 containing adapter proteins play an important role in cytokine signals, and this system has similarities with tyrosine kinase receptor signal transduction. STAT may mainly account for cytokine specific functions as suggested by knockout mice studies. It is of importance to note that cytokine activates multiple signaling pathways and the balance and combination of related signaling events may determine the specificity of functions of cytokines.

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Reactivated Timings of Some Major Faults in the Chugaryeong Fault Zone since the Cretaceous Period (추가령단층대 주요 단층의 백악기 이후 재활동 연대)

  • Chung, Donghoon;Song, Yungoo;Park, Changyun;Kang, Il-Mo;Choi, Sung-Ja;Khulganakhuu, Chuluunbaatar
    • Economic and Environmental Geology
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    • v.47 no.1
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    • pp.29-38
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    • 2014
  • Recently developed illite-age-analysis (IAA) approach has been applied to determine the multiple events for the Singal and Wangsukcheon faults in the Chugaryeong fault belt, Korea. Fault reactivated events during Late Cretaceous to Paleogene events($69.2{\pm}0.3$ Ma and $27.2{\pm}0.5$ Ma) for the Singal fault and of $75.4{\pm}0.8$ Ma for the Wangsukcheon fault were determined by combined approach of the optimized illite-polytype quantification and the K-Ar age-dating of clay fractions separated from the fault clays. These absolute geochronological determinations of the multiple tectonic events recorded in the Chugaryeong fault belt are crucial to establish the tectonic evolution of the Korean Peninsula since Late Cretaceous.

A Semantic Aspect-Based Vector Space Model to Identify the Event Evolution Relationship within Topics

  • Xi, Yaoyi;Li, Bicheng;Liu, Yang
    • Journal of Computing Science and Engineering
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    • v.9 no.2
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    • pp.73-82
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    • 2015
  • Understanding how the topic evolves is an important and challenging task. A topic usually consists of multiple related events, and the accurate identification of event evolution relationship plays an important role in topic evolution analysis. Existing research has used the traditional vector space model to represent the event, which cannot be used to accurately compute the semantic similarity between events. This has led to poor performance in identifying event evolution relationship. This paper suggests constructing a semantic aspect-based vector space model to represent the event: First, use hierarchical Dirichlet process to mine the semantic aspects. Then, construct a semantic aspect-based vector space model according to these aspects. Finally, represent each event as a point and measure the semantic relatedness between events in the space. According to our evaluation experiments, the performance of our proposed technique is promising and significantly outperforms the baseline methods.

A Study on Architecture of Event Driven Service System (EDS(Event Driven Service) 시스템 구조에 관한 연구)

  • Song, Kwang-Bin;Cho, Sok-Pal
    • The Journal of Information Technology
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    • v.10 no.4
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    • pp.11-26
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    • 2007
  • EDS is a typical convergence service performing convergence between functions owned by multiple SPs. EDS provides users with the relevant information and the communication by the various personal conditional environment. An alternative terminology for events for net- work related applications is 'triggers'-these are assumed to be included in the present description. Events could be defined as any activities which occur within a service avail ability, signals. Events can be managed, for example, as part of a context-aware application. EDS carry out a procedure for processing user's requested information about mobil network-based entities, such as the combination with various applications, such as a LBS (Location Based Service) and area information. In AS (Application Service) network environments, the user has his customized EDS in the network, the EDS automatically connects the appropriate Terminals consistent with a user profile. EDS can also send the collected information to other requesting users by way of event information and using the procedures of combination with other services. The user can record/retrieve the user-related information to from the information base through EDS.

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Faster Detection of Step Initiation for the Lower Limb Exoskeleton with Vertical GRF Events

  • Cha, Dowan;Kang, Daewon;Kim, Kab Il;Kim, Kyung-Soo;Lee, Bum-Joo;Kim, Soohyun
    • Journal of Electrical Engineering and Technology
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    • v.9 no.2
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    • pp.733-738
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    • 2014
  • We propose a new approach called as a peak time approach for faster detection of step initiation for the lower limb exoskeleton. As faster detection of step initiation is an important criterion in evaluating the lower limb exoskeleton, many studies have investigated approaches to detect step initiation faster, including using electromyography, the center of pressure, the heel-off time and the toe-off time. In this study, we will utilize vertical ground reaction force events to detect step initiation, and compare our approach with prior approaches. Additionally, we will predict the first step's heel strike time with vertical ground reaction force events from multiple regression equations to support our approach. The lower limb exoskeleton should assist the operator's movement much faster and more reliably with our approach.

Risk Factors for the Number of Sustained Injuries in Artisanal and Small-Scale Mining Operation

  • Ajith, Michael M.;Ghosh, Apurna K.;Jansz, Janis
    • Safety and Health at Work
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    • v.11 no.1
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    • pp.50-60
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    • 2020
  • Background: The relationship between risk factors and likelihood of occupational injury has been studied. However, what has been published has only provided a limited explanation of why some of the employees working in the same environment as other employees suffered a single-injury event, while other employees experienced multiple-injury events. This article reports on an investigation of whether artisanal and small-scale miners in Migori County of Kenya are susceptible to a single-injury or multiple-injury incidences, and if so, what underpinning parameters explain the differences between the single incident injured and the multiple incident injured group. Mine management commitment to safety in artisanal and small-scale mining (ASM) operations is also considered. Materials and methods: The research objectives were achieved by surveying 162 uninjured and 74 injured miners. A structured, closed-end questionnaire was administered to participants after the stratification of the study population and systematic selection of the representative samples. Results: The results showed that most injured miners suffer a single-injury incident rather than experiencing multiple-injury events, and laceration (28.40%) was the common injury suffered by the miners. The analysis showed that the risk factors for the single incident injured group were not similar to those in the multiple incident injured group. The research also found mine workers have low opinion about mine management/owners commitment to safety. Conclusion: The study concluded that mine management and miners need to be educated and sensitized on the dangers of this operation. Provision of safety gears and positive safety culture must be a top priority for management.

Performance Prediction of Multiple Hypothesis Tracking Algorithm (다중 가설 추적 알고리듬의 추적 성능예측)

  • 정영헌
    • Proceedings of the IEEK Conference
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    • 2003.07c
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    • pp.2787-2790
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    • 2003
  • In this paper, we predict tracking performance of the multiple hypothesis tracking (MHT) algorithm. The MHT algorithm is known to be an optimal Bayesian approach and is superior to asly other tracking filters because it takes into account the events that the measurements can be originated from new targets and false alarms 3s well as interesting targets. In the MHT algorithm, a number of candidate hypotheses are generated and evaluated later as more data are received. The probability of each candidate hypotheses is approximately evaluated by using the hybrid conditional average approach (HYCA). We performed numerical experiments to show the validity of our performance prediction.

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Recent Insights from the International Common-Cause Failure Data Exchange Project

  • Kreuser, Albert;Johanson, Gunnar
    • Nuclear Engineering and Technology
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    • v.49 no.2
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    • pp.327-334
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    • 2017
  • Common-cause failure (CCF) events can significantly impact the availability of safety systems of nuclear power plants. For this reason, the International Common Cause Data Exchange (ICDE) project was initiated by several countries in 1994. Since 1997 it has been operated within the Organisation for Economic Co-operation and Development (OECD)/Nuclear Energy Agency (NEA) framework and has successfully been operated over six consecutive terms (the current term being 2015-2017). The ICDE project allows multiple countries to collaborate and exchange CCF data to enhance the quality of risk analyses, which include CCF modeling. As CCF events are typically rare, most countries do not experience enough CCF events to perform meaningful analyses. Data combined from several countries, however, have yielded sufficient data for more rigorous analyses. The ICDE project has meanwhile published 11 reports on the collection and analysis of CCF events of specific component types (centrifugal pumps, emergency diesel generators, motor operated valves, safety and relief valves, check valves, circuit breakers, level measurement, control rod drive assemblies, and heat exchangers) and two topical reports. This paper presents recent activities and lessons learnt from the data collection and the results of topical analysis on emergency diesel generator CCF impacting entire exposed population.

Semantic Event Detection in Golf Video Using Hidden Markov Model (은닉 마코프 모델을 이용한 골프 비디오의 시멘틱 이벤트 검출)

  • Kim Cheon Seog;Choo Jin Ho;Bae Tae Meon;Jin Sung Ho;Ro Yong Man
    • Journal of Korea Multimedia Society
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    • v.7 no.11
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    • pp.1540-1549
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    • 2004
  • In this paper, we propose an algorithm to detect semantic events in golf video using Hidden Markov Model. The purpose of this paper is to identify and classify the golf events to facilitate highlight-based video indexing and summarization. In this paper we first define 4 semantic events, and then design HMM model with states made up of each event. We also use 10 multiple visual features based on MPEG-7 visual descriptors to acquire parameters of HMM for each event. Experimental results showed that the proposed algorithm provided reasonable detection performance for identifying a variety of golf events.

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Predictors of Depression in Mothers with Young Children by Income status (유아기 자녀를 둔 기혼여성의 우울에 대한 영향 요인: 저소득층과 중산층 비교를 중심으로)

  • Lee, In Jeong
    • Korean Journal of Health Education and Promotion
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    • v.31 no.1
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    • pp.27-43
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    • 2014
  • Objectives: The purpose of this study was to evaluate depression of mothers with children in early childhood and to identify predictors by income level. Methods: The research was conducted with 1,761 data from the 3rd wave of the Panel Study of Korean Children(PSKC) data. Independent variables were socio-demographic data, self-esteem, normative life-events, non-normative life events, parenting stress, marital conflict, social support. Data were analyzed by t-test, ANOVA, hierarchical multiple regression analysis were conducted. Results: Significant factors of depression of female in low-income were non-normative life events, parenting stress, marital conflict. In middle class, significant factors were education, birth order of children, self-esteem, normative and non-normative life events, parenting stress, marital conflict, sociable support. At last, we found that marital conflict was the biggest factor for depression of female in low-income and parenting stress was the most powerful predictor in middle class. Conclusions: Mother's depression has a enormous impacts on development of children in early childhood. Therefore It is required to prevent depression in mothers and it is important to intervene at the early stage of depression. Results of this study showed a different pattern of predictors by income level. Therefore, Intervention and services for a mother's depression should change the direction depending on the level of income.