• Journal of Institute of Control, Robotics and Systems
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• v.7 no.6
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• pp.477-486
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• 2001

Many physical systems can be modeled by incorporating continuous and discrete event nature together. Such hybrid systems contain both continuous and discrete states that influence the dynamic be-havior of the systems. There has been an increasing interest in thers types of systems during the last dec-ade, mostly due to the growing usage of computers in the control of physical plants but also as a result of the hybrid nature of physical processes. The stability theory for hybrid systems is considered as extension of Lyapunov theory where the existence of an abstract energy function satisfying certain properties verifies stability, called multiple Lyapunov theory. In this paper, a hybrid stabilizing controller is proposed using the control Lyapunov function method and multiple Lyapunov theory, and the proposed method is applied to lon-gitudinal spacing control in a vehicle platoon for intelligent transportation systems(ITS).

• The Journal of the Acoustical Society of Korea
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• v.11 no.4
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• pp.22-30
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• 1992

The propagation of coherent time-harmonic elastic SH waves in a medium with random distribution of cylindrical inclusions is studied for characterizing the dynamic elastic modulus and the attenuation property of fiber-reinforced composite materials. A multiple scattering theory using the single scattering coefficients in conjunction with the Lax's quasicrystalline approximation is derived and from which the dispersion relation for such medium is obtained. The pair-correlation functions between the cylinders which are needed to formulate the multiple scattering interaction between the cylinders are obtained by Monte Carlo simulation method.From the numerically calculated complex wavenumbers, the propagation speed of the average wave, the coherent attenuation coefficient and the effective shear modulus are presented as functions of frequency and area density.

• BMB Reports
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• v.44 no.1
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• pp.11-21
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• 2011

During the last decade small regulatory RNA (srRNA) emerged as central players in the regulation of gene expression in all kingdoms of life. Multiple pathways for srRNA biogenesis and diverse mechanisms of gene regulation may indicate that srRNA regulation evolved independently multiple times. However, small RNA pathways share numerous properties, including the ability of a single srRNA to regulate multiple targets. Some of the mechanisms of gene regulation by srRNAs have significant effect on the abundance of free srRNAs that are ready to interact with new targets. This results in indirect interactions among seemingly unrelated genes, as well as in a crosstalk between different srRNA pathways. Here we briefly review and compare the major srRNA pathways, and argue that the impact of srRNA is always at the system level. We demonstrate how a simple mathematical model can ease the discussion of governing principles. To demonstrate these points we review a few examples from bacteria and animals.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.17 no.12
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• pp.1353-1361
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• 1992

Holographic optical element(HOE) is fabricated with the properties of lightweight, thin thickness and interconnectivity for free space. Particularly, HOE for optical interconnection and multiple image processing should have a high efficiency and equal spot intensity, Nonlinear equations for 2-dimensional binary phase grating(BPG) structure is solved by computer simulation based on modified Newton method. Computer-generated pattern drawn by plotter is scaled down and translated into the microfilm. After contact printing between the microfilm and silver halide hologram film, phase diffraction grating produces the $5{\times}5$ multiple spots. Experimental results are shown that bleached phase grating has a high efficiency and equal focused beams except central zero order.

• Journal of the Korean Operations Research and Management Science Society
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• v.37 no.1
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• pp.1-18
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• 2012

The present study provides some extensions over a recent work in Won (2011) which investigates properties of the static newsvendor problem under a schedule involving progressive multiple discounts under the assumption that demand is given exogenously. Khouja (1995, 1996) formulated the extended versions over the classical newsvendor model with various discount policies including all-units discount and/or multiple discounts and found that the extended newsvendor models with discount schedules yield higher optimal expected profits than the classical newsvendor model with no-discounts. In this study, we establish a robust conjecture as a stronger statement than Khouja's findings with regard to the general relationship among the expected profits of newsvendor models in the sense that the conjecture holds for every order quantity as well as the optimal order quantity. The conjecture encourages the newsvendor facing quantity discounts to safely implement her own discounts policy to customer or accept quantity discounts offered by the supplier even if the optimal order quantity cannot be ordered due to additional restrictions such as budget or warehouse capacity constraints because the newsvendor models with quantity discounts always yield higher expected profit than the classic newsvendor model without quantity discounts regardless of the order quantity. Results from wide experiments with various probability distributions of demand strongly support our conjecture.

• International Journal of Aeronautical and Space Sciences
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• v.14 no.3
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• pp.264-271
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• 2013

A method of multiple transport-aircraft mission modeling is proposed in order to improve the efficiency of evaluating and optimizing pre-mission plans. To deal with the challenge of multiple transport-aircraft missions, the object-oriented modeling method is utilized. The elements of the mission are decomposed into objects and businesses, And the major mission objects and their important properties are summarized. A complex mission can be broken down into basic business modules such as the ground section and flight section. The business models of loading and fueling services in the ground section are described. The business model of the flight section is composed of an air route and flight profile with the flight equation and the fuel consumption model. The logical relationship of objects and business modules is introduced. The architecture of the simulation system, which includes a database, computation module, graphical user interface (GUI) module, and a result analysis module, is established. A sample case that includes two different plans is provided to verify the model's ability to achieve multi-aircraft composite mission simulation.

• Journal of Ocean Engineering and Technology
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• v.29 no.2
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• pp.135-142
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• 2015

The float over method is the most preferred method for installing heavy topside onto a jacket platform. A very complex platform with multiple jacket structures on a specific field requires multiple installation procedures. This study validated the installation of two topsides using a single installation barge to reduce the operation and installation cost. The hydrodynamic properties of the installation barge during the installation of two topsides were calculated. The tension and fender forces during docking were investigated to show the validity of the proposed dual topside installation method. In conclusion, the operational safety of the proposed procedure was validated through the calculation of the motion of the installation vessel and loads on the jacket legs.

• Structural Engineering and Mechanics
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• v.45 no.6
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• pp.837-851
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• 2013

In construction industry, strength is a primary criterion in selecting a concrete for a particular application. The concrete used for construction gains strength over a long period of time after pouring the concrete. The characteristic strength of concrete is defined as the compressive strength of a sample that has been aged for 28 days. Neither waiting for 28 days for such a test would serve the rapidity of construction, nor would neglecting it serve the quality control process on concrete in large construction sites. Therefore, rapid and reliable prediction of the strength of concrete would be of great significance. On this backdrop, the method is proposed to establish a predictive relationship between properties and proportions of ingredients of concrete, compaction factor, weight of concrete cubes and strength of concrete whereby the strength of concrete can be predicted at early age. Multiple regression analysis was carried out for predicting the compressive strength of concrete containing Portland Pozolana cement using statistical analysis for the concrete data obtained from the experimental work done in this study. The multiple linear regression models yielded fairly good correlation coefficient for the prediction of compressive strength for 7, 28 and 40 days curing. The results indicate that the proposed regression models are effectively capable of evaluating the compressive strength of the concrete containing Portaland Pozolana Cement. The derived formulas are very simple, straightforward and provide an effective analysis tool accessible to practicing engineers.

• Steel and Composite Structures
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• v.29 no.5
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• pp.635-645
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• 2018

Beam-column joints play a significant role in static and dynamic performances of reinforced concrete frame structures. This study contributes a numerical approach of topologically optimal design of carbon fiber reinforced plastics (CFRP) to retrofit existing beam-column connections with crack patterns. In recent, CFRP is used commonly in the rehabilitation and strengthening of concrete members due to the remarkable properties, such as lightweight, anti-corrosion and simplicity to execute construction. With the target to provide an optimal CFRP configuration to effectively retrofit the beam-column connection under semi-failure situation such as given cracks, extended finite element method (X-FEM) is used by combining with multi-material topology optimization (MTO) as a mechanical description approach for strong discontinuity state to mechanically model cracked structures. The well founded mathematical formulation of topology optimization problem for cracked structures by using multiple materials is described in detail in this study. In addition, moved and regularized Heaviside functions (MRHF), that have the role of a filter in multiple materials case, is also considered. The numerical example results illustrated in two cases of beam-column joints with stationary cracks verify the validity, benefit and supremacy of the proposed method.

• Biomolecules & Therapeutics
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• v.27 no.2
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• pp.152-159
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• 2019

Multiple sclerosis (MS) is an autoimmune disease characterized by progressive neuronal loss, neuroinflammation, axonal degeneration, and demyelination. Previous studies have reported that 6-shogaol, a major constituent of ginger (Zingiber officinale rhizome), and its biological metabolite, 6-paradol, have anti-inflammatory and anti-oxidative properties in the central nervous system (CNS). In the present study, we investigated whether 6-shogaol and 6-paradol could ameliorate against experimental autoimmune encephalomyelitis (EAE), a mouse model of MS elicited by myelin oligodendrocyte glycoprotein ($MOG_{35-55}$) peptide immunization with injection of pertussis toxin. Once-daily administration of 6-shogaol and 6-paradol (5 mg/kg/day, p.o.) to symptomatic EAE mice significantly alleviated clinical signs of the disease along with remyelination and reduced cell accumulation in the white matter of spinal cord. Administration of 6-shogaol and 6-paradol into EAE mice markedly reduced astrogliosis and microglial activation as key features of immune responses inside the CNS. Furthermore, administration of these two molecules significantly suppressed expression level of tumor necrosis $factor-{\alpha}$, a major proinflammatory cytokine, in EAE spinal cord. Collectively, these results demonstrate therapeutic efficacy of 6-shogaol or 6-paradol for EAE by reducing neuroinflammatory responses, further indicating the therapeutic potential of these two active ingredients of ginger for MS.