• 가정∙방문간호학회지
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• 제27권3호
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• pp.321-329
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• 2020

Purpose: This study was conducted to assess the factors that affect the confidence of nurses at small and medium-sized hospitals in the control of infections caused by multidrug-resistant organisms and to establish basic data for the interventional strategy to improve the nurses' execution of the control of infection caused by multidrug-resistant organisms. Methods: A total of 154 nurses working at four small and medium-sized hospitals situated in City C were selected as participants of this study. Data were collected using a structured questionnaire and analyzed using the IBM SPSS 21.0 software. Results: Confidence in controlling infections caused by multdrug-resistant organisms had a positive correlation with the level of knowledge of this control and the health beliefs of the nurses. Factors that affect nurses' confidence in controlling infections caused by multidrug-resistant organisms included perceived benefits (β=.431, p<.001) and knowledge (β=.354, p<.001) with an explanatory power of 36.4%. Conclusion: It was found that the nurses have higher confidence in executing their duties with higher perceived benefits of and knowledge about the control of infections caused by multidrug-resistant organisms. As such, it is deemed necessary to establish strategies to elevate the advantages of and knowledge about infection prevention activities at the time of training/education on controlling infections caused by multidrug-resistant organisms.

• 산업융합연구
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• 제20권11호
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• pp.205-211
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• 2022

본 연구는 임상실습을 경험한 간호대학생의 다제내성균에 대한 지식 정도와 감염관리 이행수준을 파악하기 위한 서술적 조사연구이다. 2020년 11월 1일부터 2021년 3월 10일까지 D시에 소재한 2개 간호학과에 재학 중인 3학년과 4학년 간호대학생 212명을 대상으로 설문조사를 실시하였다. 수집된 자료는 IBM SPSS/WIN 25.0 통계 프로그램을 이용하여 분석하였다. 연구결과 다제내성균 지식과 다제내성균 감염관리 이행은 유의한 양의 상관관계(r=.40, p<.001)를 보였다. 따라서 간호대학생의 다제내성균 감염관리 이행수준을 높이기 위해서는 교육과정과 임상실습에서 다제내성균에 대한 이론 및 실습 지침을 구체적으로 마련하고 다제내성균 감염관리 교육으로 지식을 높이는 것이 필요하다.

• 보건의료산업학회지
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• 제8권4호
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• pp.163-173
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• 2014

This study was performed to investigate the current status of isolation precautions of multidrug resistant organisms(MDROs) in general hospitals with more than 200bed. The questionnaires were mailed from 3rd, April 2013 to 30th, April 2013. Methicillin resistant Staphylococcus aureus:(MRSA), vancomycin resistant Staphylococcus aureus:(VRSA), vancomycin resistant Enterococcus(VRE), multidrug-resistant Acinetobacter baumannii, carbapenem-resistant Enterobacteriaceae multidrug-resistant Pseudomonas aeruginosa were enrolled. MRSA(100.0%) and VRE(98.7%) were isolated respectively. VRE(97.3%) and MRSA(64.0%) were regulated strictly respectively. VRE(91.5%) and VRSA(50.7%) were isolated in a single room respectively. Hospital being located in Seoul(p<0.001), and beds(${\geq}600$)(p=0.008) were different significantly. The isolation space limitation(71.1%) was the highest difficulty. The development of refunding the costs of the extra supplies and other hygienic materials for infection control was discovered as the most urgent strategy.

• 가정∙방문간호학회지
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• 제30권2호
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• pp.155-162
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• 2023

Purpose: This study was conducted to identify the status and risk factors for the carriage of multidrug-resistant organisms carriage in home health nursing patients. Methods: This retrospective study enrolled 122 participants who received home health nursing and analyzed the data obtained from chart review and diagnostic tests for multidrug-resistant organisms carriage from January 2019 to January 2021. Results: Multivariate analysis revealed that surgical procedures in the preceding year, injectable antibiotic use in the preceding month, pressure ulcer, and indwelling nasal tubes were significantly associated with multi-drug resistant infection. Conclusions: Infection-control strategies need to be developed and customized for use in the home health-nursing service for patients who are carriers of multidrug-resistant organisms.

• Journal of Korean Biological Nursing Science
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• 제14권1호
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• pp.8-15
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• 2012

Purpose: This study was undertaken to identify the knowledge and compliance level of nursing students. It was based on self-administered questionnaires about multidrug-resistant organisms (MDROs). Methods: The test group was 184 nursing students who had contact with MDROs during clinical practice. The study was conducted from May 1 to September 16, 2011. Results: The average knowledge level of MDROs was 16.20 (correct answer rate: 67.5%). The nurses' compliance level of MDROs infection control was on average 40.50 (range: 13-52). "Hand hygiene" ranked highest in the compliance level of MDROs infection control. The lowest level of MDRO infection control was the wearing of disposable aprons or gowns. Conclusion: This study demonstrated the nursing students' knowledge and the compliance level of infection control. We suggest that nursing students receive mandated systematic education of MDROs in the nursing curriculum. And clinical practice experience of MDROs infection control is required in hospitals. These steps will help prevent transmission of MDROs in nursing settings.

• 디지털융복합연구
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• 제19권4호
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• pp.159-166
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• 2021

본 연구는 중소병원 간호사를 대상으로 다제내성균 감염관리 시뮬레이션 프로그램을 개발하고 개발된 다제내성균 감염관리 시뮬레이션 교육 프로그램의 효과를 평가하기 위해 시도되었다. 본 연구는 중소병원에 근무하는 간호사 33명을 대상으로 시행한 단일군 전·후 실험설계연구이다. 수집된 자료는 IBM SPSS 21.0 프로그램을 이용하여 분석하였으며 대상자의 일반적 특성, 다제내성균 감염관리 지식과 수행도는 기술통계 분석하였고 프로그램 적용 전후 지식과 수행도의 차이는 paired t-test로 분석하였다. 연구결과 시뮬레이션 프로그램 적용 후 간호사의 다제내성균 감염관리 지식(t=-10.764, p<.001)과 감염관리 수행도(t=-4.215, p<.001)가 통계적으로 유의하게 높아졌다. 의료기관 내 다제내성균 전파 차단 및 유행발생을 예방하기 위해 간호사의 감염관리 지식과 수행도 향상이 중요하므로 향후 다양한 시뮬레이션 프로그램 개발이 필요하다.

• 중환자간호학회지
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• 제11권1호
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• pp.89-100
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• 2018

Purpose : The purpose of this study was to analyze factors influencing the adherence to guidelines for intensive care unit (ICU) nurses to control infections due to multidrug-resistant organisms (MDRO). Method : Participants were 194 ICU nurses at 3 university hospitals. Questions for the survey inquired about attitude, subjective norms, perception of patient safety culture to carry out MDRO management guidelines, perceived behavior control (PBC), and intention, based on the theory of planned behavior. Path analysis were utilized. Results : The path analysis presented that PBC, perception of patient safety culture, and intent had a direct effect on MDRO management guidelines. Attitude towards following the manual did not have any correlation. The hypothetical model based on the theory of planned behavior was revealed as applicable; the degree of the variance in explaining adherence to the manual was 23 %, and the variance in explaining intention to fulfill the manual was 33 %. Conclusion : The results of this study suggest that we should develop a program to improve PBC to increase adherence to MDRO management guidelines. ICU nurses' perceptions of patient safety culture should also be surveyed.

• 한국미생물·생명공학회지
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• 제42권2호
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• pp.152-161
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• 2014

The in vitro antimicrobial potential of the unexplored Moringa oleifera seed coat (SC) was evaluated against some Gram-positive and Gram-negative bacteria and yeast pathogens. Antimicrobial studies with various solvent extracts indicated ethyl acetate to be the best extractant, which was used for the rest of the antimicrobial studies as it tested neither toxic nor mutagenic. Gram-positive bacteria including a methicillin resistant Staphylococcus aureus (MRSA) strain were more susceptible with a minimum inhibitory concentration (MIC) range of 0.03-0.04 mg/ml. The antimicrobial pharmacodynamics of the extract exhibited both concentration-dependent and time-dependent killing. Most of the test organisms exhibited a short post antibiotic effect (PAE) except Enterococcus faecalis, Staphylococcus aureus, and Klebsiella pneumoniae 1, which exhibited longer PAEs. Amongst the major phytoconstituents established, flavonoids, diterpenes, triterpenes and cardiac glycosides exhibited inhibitory properties against most of the test organisms. The identified active phytochemicals of the M. oleifera seed coat exhibited antimicrobial potential against a wide range of medically important pathogens including the multidrug-resistant bugs. Hence, the M. oleifera seed coat, which is usually regarded as an agri-residue, could be a source of potential candidates for the development of drugs or drug leads of broad spectrum that includes multidrug-resistant bugs, which are one of the greatest concerns of the $21^{st}$ century.

• 공업화학
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• 제22권2호
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• pp.119-124
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• 2011

현재, 사람들은 많은 병에 노출되어 있다. 산업화의 빠른 변화는 생산시설의 자동화, 정보 통신 산업기술의 발달로 삶의 질이 향상되었으나, 신체활동의 감소와 환경오염으로 인해 환경적 스트레스와 병원균 감염 반응에 대한 인간의 면역체계가 악화되었다. 아울러 현재 약물의 오 남용으로 다재약물내성을 갖는 미생물들(multidrug-resistant microbes)과 암세포(tumor)의 출현으로 인해 새로운 항생제 개발이 시급하다. 그들 중 하나가 항생 펩타이드(antibiotic peptide)로 기존 약물과 비교하면 약물저항성이 거의 일어나지 않는다. 여러 가지 항생활성을 가지는 펩타이드들은 다양한 생명체로부터 동정되고 있다. 이 논문은 항생 펩타이드들의 활성과 적용분야에 대해 논하려 한다.

• 기본간호학회지
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• 제22권3호
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• pp.268-276
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• 2015

Purpose: The purpose of this study was to identify factors which influence the management of MultiDrug -Resistant Organisms (MDROs) by nurses in Intensive Care Units (ICUs). Methods: Data were collected from December 8 to 20, 2013 and participants were 163 ICU nurses working in one general hospital. The Health Belief Model tool and knowledge and management of MDROs infection tools were used in the study. Descriptive statistics, t-test, analysis of variances, Pearson correlation coefficients and multiple regression were used to analyze the data. Results: Knowledge, perceived susceptibility, and perceived benefits had a significant influence on MRSA (Methicillin Resistant Staphylococcus Aureus,) and MDRAB (Multidrug Resistant Acinetobacter Baumannii) infection management when all the other variables were considered. Significant variable which had influence on VRE (Vancomycin Resistant Eenterococci) infection management were perceived susceptibility and perceived benefits. Conclusion: Perceived susceptibility and perceived benefits had significant influence on MDROs infection management. Emphasis needs to be on the perceived susceptibility and perceived benefits of MDROs infection management when providing an educational program for ICU nurses.