• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.2
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• pp.261-268
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• 2018

The study used the simplified flooding analysis model, SIMOD, to distribute the total flood discharge by time, so research on flooding in urban areas can be conducted. The conventional flooding analysis models have limitations in constructing input data and take a long time for analysis. However, SIMOD is useful because it supports rapid decision-making process using quick modeling based on simple hydrological data, such as topography and inflow flood of the study area, to analyze submerged routes formed by flooding. Therefore, the study used the SIMOD model to analyze flooding in urban areas before conducting a comparative study with the outputs from FLO-2D, which is one of the conventional flooding analysis models, to identify the model's applicability. Seongseoje was selected as the study area, as it is located downstream the Geumho river where streams flow in the adjacent areas, and dikes are high enough to apply the "Overflow and Break" scenario for urban areas. With regard to topography, the study applied DEM data for the conventional flooding analysis and DSM data to represent urban building communities, distribution of roads, etc. Input flood discharge was calculated by applying the rectangular weir equation under the bank and break scenario through a 200-year return period of a design flood level. Comparative analysis was conducted in a flooded area with a simulation time of 1-24 hours. The time for the 24-hour simulation in SIMOD was less than 7 minutes. Compared with FLO-2D, the difference in flooded areas was less than 20%. Furthermore, the study identified the need for topography data using DSM for urban areas, as the analysis result that applies DSM showed the influence of roads and buildings.

• The Journal of the Korea Contents Association
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• v.8 no.5
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• pp.246-259
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• 2008

This study was to minimize the trial and error in the primary step of the C4I system(ATCIS) of the each army corps on the front line, and test the economy and efficiency was tested by reviewing related papers and the system characteristics of other countries. The relationship was researched by analyzing the collected survey data and survey data related to the user's requirement level such as the army standards, that is, commonality, timeliness, simplification, automaticity, field availability and viability, multi-stage security and interoperability, unification. The result showed that the C4I system was efficiently operated through the system reliability for the specification of the system and operation manual, maneuverability and security, adaptability of the war field and system support and management, and good education and training about system operation, and less system maintenance and supplementary element. As a result, the development plan confirmed that the continuous operator education and the construction of the maintenance, and the upgrade digitalization(C4ISR+D) with the korean characteristics based on IT of network systems, and system development of the measurement model of the operator performance must be continuously supplemented in the near future.

• Journal of Microbiology and Biotechnology
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• v.14 no.1
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• pp.81-89
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• 2004

Tumor necrosis factor-$\alpha$ (TNF-$\alpha$) and lymphotoxin-$\alpha$ (LT-$\alpha$, TNF-$\beta$) can initiate and perpetuate human diseases such as multiple sclerosis (MS), rheumatoid arthritis (RA), and insulin-dependent diabetes mellitus (IDDM). TNFs can be blocked by the use of soluble TNF receptors. However, since monomeric soluble receptors generally exhibit low affinity or function as agonists, the use of monomeric soluble receptors has been limited in the case of cytokines such as TNF-$\alpha$, TNF-$\alpha$, interleukin (IL)-1, IL-4, IL-6, and IL-13, which have adapted to a multi component receptor system. For these reasons, very high-affinity inhibitors were created for the purpose of a TNFs antagonist to bind the TNFR and trigger cellular signal by using the multistep polymerase chain reaction method. First, recombinant simple TNFR-Ig fusion proteins were constructed from the cDNA sequences encoding the extracellular domain of the human p55 TNFR (CD120a) and the human p75 TNFR (CD120b), which were linked to hinge and constant regions of human $IgG_1$ heavy chain, respectively using complementary primers (CP) encoding the complementary sequences. Then, concatameric TNFR-Ig fusion proteins were constructed using recombinant PCR and a complementary primer base of recombinant simple TNFR-Ig fusion proteins. For high level expression of recombinant fusion proteins, Chinese hamster ovary (CHO) cells were used with a retroviral expression system. The transfected cells produced the simple concatameric TNFR-Ig fusion proteins capable of binding TNF and inactivating it. These soluble versions of simple concantameric TNFR-Ig fusion proteins gave rise to multiple forms such as simple dimers and concatameric homodimers. Simple TNFR-1g fusion proteins were shown to have much more reduced TNF inhibitory activity than concatameric TNFR-Ig fusion proteins. Concatameric TNFR-Ig fusion proteins showed higher affinity than simple TNFR-Ig fusion proteins in a receptor inhibitor binding assay (RIBA). Additionally, concatameric TNFR-Ig fusion proteins were shown to have a progressive effect as a TNF inhibitor compared to the simple TNFR-Ig fusion proteins and conventional TNFR-Fc in cytotoxicity assays, and showed the same results for collagen induced arthritis (CIA) in mice in vivo.

• The Journal of the Korea Contents Association
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• v.19 no.11
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• pp.122-131
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• 2019

This study analyzed the moderating effect according to school levels in the structural relationship between stressful interpersonal relationships at work and rumination in teachers' depression. For this study, a research model was formed based on theoretical understandings and a literature review. The researchers surveyed 811 teachers at primary and secondary schools to measure scales of depression, rumination, and stress in interpersonal relationships at work. Primary education and secondary education were the grouping variables for the school levels, and the collected data was analyzed using multi-group structural equation modeling. Also, to affirm equivalence between the two models, the data was investigated using the constrained model of measurement equivalence. The research results verified the equivalence between the two models and the moderating effect by comparing the path coefficients of the two models on the assumption of equivalence constraint. As a result, the moderating effect according to school levels was revealed on the path from stressful interpersonal relationships at work to depression. Grounded on this analysis, stress in interpersonal relationships at work mediates the impact of rumination in teachers' depression. In addition, the research revealed that the moderating effects on stressful interpersonal relationships at work varied according to school level, and the moderating effect of stress in interpersonal relationships at work affected middle school teachers but not primary school teachers.

• Korean Journal of Remote Sensing
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• v.27 no.4
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• pp.435-444
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• 2011

The land cover map derived from spectral features of high resolution optical images has low spectral resolution and heterogeneity in the same land cover class. For this reason, despite the same land cover class, the land cover can be classified into various land cover classes especially in vegetation area. In order to overcome these problems, detailed vegetation classification is applied to optical satellite image and SAR(Synthetic Aperture Radar) integrated data in vegetation area which is the result of pre-classification from optical image. The pre-classification and vegetation classification were performed with MLC(Maximum Likelihood Classification) method. The hierarchical land cover classification was proposed from fusion of detailed vegetation classes and non-vegetation classes of pre-classification. We can verify the facts that the proposed method has higher accuracy than not only general SAR data and GLCM(Gray Level Co-occurrence Matrix) texture integrated methods but also hierarchical GLCM integrated method. Especially the proposed method has high accuracy with respect to both vegetation and non-vegetation classification.

• Journal of Korean Society of Transportation
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• v.27 no.6
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• pp.119-127
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• 2009

It has been known that bus route and company related characteristics have influences on punctuality, but fewer research have been conducted. Independent variables used in this study were selected using correlation analysis, and OLS(Ordinary Least Square) and HLM(Hierarchical Linear Model) were employed to identify factors affecting bus punctuality(headway deviation). The results showed that ICC(intraclass Correlation Coefficient) is 0.10, indicating that hierarchical linear models are more adequate for these data because there is effective variation in the subjects between companies. Punctuality was found to be negatively associated with the number of vehicles, the number of persons per vehicle, and total travel time. On the other hand, average headway and company size have a positive relationship with punctuality. Therefore, the number of vehicles per route, average headway, and the number of vehicles managed by a company should be considered for more accurately evaluating the management of piunctuality.

• Toxicological Research
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• v.33 no.3
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• pp.225-231
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• 2017

National reference standards (NRSs) for biologics are established through potency estimation by a multi-center joint study of standard materials used in the approval process for national lot release and quality control of vaccines, blood products, and other biologics. In this study, a stability evaluation was conducted to determine whether the potency of NRSs for six blood products was being maintained at a consistent level in Korea. The present study conducted real-time stability tests via in-vivo/in-vitro bioassay on NRSs for blood coagulation factor VIII concentrate (2nd standard), antithrombin concentrate, prekallikrein activator, anti-hepatitis B immunoglobulin, blood coagulation factor IX concentrate, and anti-tetanus human immunoglobulin, as well as a trend analysis using cumulative annual results. The real-time stability test results showed that the mean potency of six NRSs was all within the control limit. In the trend analysis, the potency of NRS for blood coagulation factor VIII concentrate (2nd standard) showed a decreasing trend, while the potency of all other products had been stably maintained. The present study confirmed that the mean potency of NRSs for six blood products had been stably maintained in Korea. The findings of the present study establish a foundation that can ensure the quality of NRSs for biologics in Korea, and it is expected to make a major contribution to the supply of high-quality biologics.

• Journal of Preventive Medicine and Public Health
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• v.38 no.4
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• pp.391-400
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• 2005

Objective : This study examined the socioeconomic differentials for the health and health related behaviors among South Korean middle school students. Methods : A nationwide cross-sectional interview survey of 3,449 middle school second-grade students and their parents was conducted using a stratified multi-stage cluster sampling method. The response rate was 93.3%. The socioeconomic position indicators were based on self-reported information from the students and their parents: parental education, father's occupational class, monthly family income, out-of-pocket expenditure for education, housing ownership, educational expectations, educational performance and the perceived economic hardships. The outcome variables that were measured were also based on the self-reported information from the students. The health measures included self-rated health conditions, psychological or mental problems, the feelings of loneliness at school, the overall satisfaction of life and the perceived level of stress. The health related behaviors included were smoking, alcohol drinking, sexual intercourse, violence, bullying and verbal and physical abuse by parents. Results : Socioeconomic differences for the health and health related behaviors were found among the eighth grade boys and girls of South Korea. However, the pattern varied with gender, the socioeconomic position indicators and the outcome measures. The prevalence rates of the overall dissatisfaction with life for both genders differed according to most of the eight socioeconomic position indicators. All the health measures were significantly different according to the perceived economic hardship. However, the socioeconomic differences in the self-rated health conditions and the psychosocial or mental problems were not clear. The students having higher socioeconomic position tended to be a perpetrator of bullying while those students with lower socioeconomic position were more likely to be a victim. Conclusions : The perceived economic hardships predicted the health status among the eighth graders of South Korea. The overall satisfaction of life was associated with the socioeconomic position indicators. Further research efforts are needed to explore the mechanisms on how and why the socioeconomic position affects the health and health related behaviors in this age group.

• Journal of Preventive Medicine and Public Health
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• v.50 no.1
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• pp.1-9
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• 2017

Objectives: By the end of the 2000s, the economic situation in many European countries started to deteriorate, generating financial uncertainty, social insecurity and worse health status. The aim of the present study was to investigate how the recent financial crisis has affected the lifestyle health determinants and behaviours of older adults living in the Mediterranean islands. Methods: From 2005 to 2015, a population-based, multi-stage convenience sampling method was used to voluntarily enrol 2749 older adults (50% men) from 20 Mediterranean islands and the rural area of the Mani peninsula. Lifestyle status was evaluated as the cumulative score of four components (range, 0 to 6), that is, smoking habits, diet quality (MedDietScore), depression status (Geriatric Depression Scale) and physical activity. Results: Older Mediterranean people enrolled in the study from 2009 onwards showed social isolation and increased smoking, were more prone to depressive symptoms, and adopted less healthy dietary habits, as compared to their counterparts participating earlier in the study (p<0.05), irrespective of age, gender, several clinical characteristics, or socioeconomic status of the participants (an almost 50% adjusted increase in the lifestyle score from before 2009 to after 2009, p<0.001). Conclusions: A shift towards less healthy behaviours was noticeable after the economic crisis had commenced. Public health interventions should focus on older adults, particularly of lower socioeconomic levels, in order to effectively reduce the burden of cardiometabolic disease at the population level.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.10A
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• pp.1003-1013
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• 2006

There is a serious problem in an 802.11g VoWLAN (Voice over Wireless LAN) terminal that talk time is less than 30% compared with an 802.11b terminal. It is almost impossible to achieve talk time level of the 802.11b MAC transmission method because IEEE 802.11g uses OFDM modulation, which is a kind of multi-carrier method and OFDM transmission speed is 54 Mbps faster than normal modulation. In this paper, a new concept of a Holdover time as a power saving method during a call with 802.11g terminal is suggested for the first time. Increase in the number of engaged terminals as a result of holdover time causes to QoS problem because of the increase in the number of back-off and then contention window. In this paper, to solve the QoS problem, a new approach is suggested such that when in down lint the sequence number of 802.11 G.711 is analyzed in the MAC of the terminal and then the Hold over time depending on loss rate is changed. Also, consumption of an electric current of 802.11b/g and MAC parameter's performance due to busy traffic caused by increase in the number of terminal are analyzed and then real data using VQT and Airopeek are analyzed.