• Title/Summary/Keyword: Mouth dryness

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The Use of Salivary Gland Scintigraphy for Diagnosis of Primary Sjögren Syndrome and Thyroid Disease in Patients with Dry Mouth

  • Park, Keun Jeong;Kim, Bok Eum;Lee, Jung Eun;Park, YounJung;Kwon, Jeong-Seung;Ahn, Hyung-Joon;Choi, Jong-Hoon
    • Journal of Oral Medicine and Pain
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    • v.44 no.4
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    • pp.179-182
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    • 2019
  • Sjögren syndrome (SS) is a chronic autoimmune disease characterized by dryness of the mouth and eyes due to lymphocytic infiltration of the exocrine glands. In American European Consensus Group (AECG) criteria, abnormal salivary gland scintigraphy (SGS) result is one of the objective signs of SS and it has been proposed as a valid and non-invasive alternative approach to functional evaluation of salivary gland, especially in the case when unstimulated whole salivary flow is more than 1.5 mL in 15 minutes or other AECG criteria is unmet. Patients with SS are more likely to have the thyroid disease (TD), but this association remains controversial. We present a case of the use of SGS for diagnosis of primary SS and TD in patients with dry mouth and burning sensation of tongue. Through this case, we suggest the usefulness of salivary scintigraphy for screening TD in addition to diagnosis of SS.

A Study on the Oral Symptoms and Oral Health-Related Quality of Life (OHIP-14) of Industrial Workers (근로자의 구강자각증상과 구강건강 관련 삶의 질)

  • Kim, Ah-Jin;Kang, Eun-Ju
    • Journal of dental hygiene science
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    • v.14 no.1
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    • pp.51-58
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    • 2014
  • The purpose of this study was to examine the symptom of dry mouth of workers, their subjective oral symptoms and factors affecting their oral health-related quality of life (Oral Health Impact Profile, OHIP-14) in an effort to provide information on the development of oral health promotion programs geared toward workers. The subjects in this study were the workers in five different companies in North Jeolla Province. After a survey was conducted from August 1 to September 20, 2012, the collected data were analyzed. The findings of the study were as follows: The office workers got 2.59 in oral dryness, and the sales associates got 1.82. The oral dryness of the former was severer than that of the latter (p<0.001). The irregular workers got 2.05 in OHIP-14, and the regular workers got 1.82 (p<0.001). Symptom of dry mouth had a positive correlation to OHIP-14 (r=0.456). OHIP-14 was positively correlated with age (r=0.209) and negatively with academic credential (r=-0.136). OHIP-14 was more significantly affected when their symptom of dry mouth was severer (${\beta}=0.383$, p<0.001), when they were older (${\beta}=0.221$, p<0.001) and when they felt they had oral diseases (${\beta}=0.146$, p<0.01). In conclusion, quality programs should be developed to promote the oral health of industrial workers in consideration of the influential factors for the oral health-related quality of life of the workers, and the government should pay more attention to related policy setting to improve the oral health of industrial workers.

Case Report of Unspecified Tremor with Xerostomia Resulting from Psychometric Drug Intake Treated by Traditional Korean Medicine (한방치료로 호전된 상세불명의 떨림과 동반된 정신과계통 약물유발성 구강건조증 치험 1례)

  • Jung, Yu-jin;Kim, Minserh;Hong, Sang-hoon
    • The Journal of Internal Korean Medicine
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    • v.39 no.5
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    • pp.914-928
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    • 2018
  • Objectives: This case report examines the effects of traditional Korean medicine for unspecified tremor with xerostomia caused by psychometric drug intake. Methods: A patient who suffered from unspecified tremor with xerostomia caused by psychometric drug intake was treated with acupuncture, pharmacopuncture, and traditional Korean medicine for 30 days. We provided the patient with herbal medicines including Ondam-tang-gagam (溫膽湯加減), Pumsimgieum-gagam (忿心氣陰加減), and Hoichunyanggyeok-san-gami (回春凉隔散加味). Symptoms were charted and evaluated using the Yin-deficiency questionnaire score, Yin-deficiency scale score, dry mouth symptom questionnaire, and visual analogue scale. Results: After treatment with Korean Medicine and pharmacopuncture, the frequency and degree of tremor has decreased, and degree of Xerostomia also improved. The Scores of Yin-deficiency questionnaire score, Yin-deficiency scale score, dry mouth symptom questionnaire, and visual analogue scale were also improved. And we could see reduction in the level of distribution of gastrointestinal heat at Digital Infrared Thermal Imaging test. The patient's Symtoms (Xerostomia as well as unspecified tremor) were improved after treated with Korean Medicine and pharmacopuncture. Conclusion: Korean medicine treatments may be valuable for xerostomia caused by psychometric drug intake.

A Case Report of Spinal Pharmacopuncture and Herb Medicine for Dry Mouth (구강건조증 환자에 대한 척추 약침 및 한약 치료 1례)

  • Jin, Joon-soo;Min, Baek-ki;Lee, Do-eun;Seo, Ho-seok;Kim, Jin-won
    • The Journal of Internal Korean Medicine
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    • v.40 no.2
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    • pp.262-269
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    • 2019
  • Xerostomia is a symptom of subjective complaints due to decreased salivary secretion or various other causes, which is common in about 30% of elderly people. Parasympathetic stimulants or artificial saliva are used as remedies, but this has side effects, and there are limitations in completely resolving symptoms. In this study, an 88-year-old woman with subjective dry mouth syndrome for the previous two to three years was treated with spinal pharmacopuncture and herbal medicine (Yookmigihwang-tang). The patient received pharmacopuncture at the thoracic 3rd, 6th, and 10th level twice a day and took herbal medicine three times daily for seven days. Both the degree of oral dryness and behavior were improved after treatment of Korean medicine, especially in the case of pharmacopuncture for inner core muscles.

The Voice Characteristics of Children with Palatine Tonsil and Adenoid Hypertrophy (구개편도와 아데노이드 비대 아동의 음성 특성)

  • Song, Yun-Kyung
    • The Journal of the Acoustical Society of Korea
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    • v.28 no.8
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    • pp.790-795
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    • 2009
  • This study evaluated the voice of 68 normal children and 50 children with palatine tonsil and adenoid hypertrophy with MDVP to examine the hypothesis that their mouth breathing makes the vocal folds dry and this condition contributes to lower the level of voice quality. The results showed that children with palatine tonsil and adenoid hypertrophy had statistically significant elevations in Jitt, RAP, PPQ, Shim and APQ parameters, and had the lower level of voice quality. Therefore, the children with palatine tonsil and adenoid hypertrophy need vocal hygiene education.

Clinical Characteristics and Distribution of the Tongue-Related Diagnoses of Patients with Tongue Symptoms

  • Park, Jae-Man;Kim, Ji Hoo;Park, Hyun-Jeong;Ahn, Jong-Mo
    • Journal of Oral Medicine and Pain
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    • v.47 no.3
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    • pp.109-116
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    • 2022
  • Purpose: This study was conducted to analyze the clinical characteristics and distribution of the tongue-related diagnoses in patients with tongue symptoms. Methods: The subjects were patients who visited Chosun University Dental Hospital with tongue symptoms from January 1, 2021, to December 31, 2021. We analyzed 491 patients (139 males and 352 females) with tongue-related diagnostic code names in the Korean Standard Classification of Disease (KCD) in the Electronic Medical Record (Dentopinformation Technology Co., Seoul, Korea). Results: On analyzing the diagnoses of tongue diseases using the KCD, glossopyrosis (44.8%) and painful tongue (15.2%) showed high rates. Of the 491 patients, 139 (28.3%) were males and 352 (71.7%) were females, and the average age was 58.1 years. As for systemic diseases, there were many patients with diseases of the circulatory system (27.0%) and endocrine, nutritional, and metabolic diseases (13.7%). Tongue symptoms were discomfort in 58 patients, pain in 329 patients, paresthesia in 10 patients, burning sensations in 222 patients, dysgeusia in 25 patients, dryness in 110 patients, fissures in 57 patients, and other symptoms in 72 patients. Areas with tongue symptoms were the anterior area in 102 patients, the lateral area in 140 patients, the posterior area in 12 patients, the dorsal area in 140 patients, the ventral area in 42 patients, and which area in 126 patients overall. Patients with burning mouth syndrome and oral candidiasis had significantly more tongue symptoms. Conclusions: Patients with tongue symptoms exhibited a variety of tongue diseases. Tongue symptoms were more common in women over 50 years of age and were frequently seen in patients with burning mouth syndrome and oral candidiasis.

Schisandra Chinensis Inhibits Oxidative DNA Damage and Lipid Peroxidation Via Antioxidant Activity

  • Jeong, Jin-Boo;Jeong, Hyung-Jin
    • Korean Journal of Plant Resources
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    • v.22 no.3
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    • pp.195-202
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    • 2009
  • Schisandra chinensis have been traditionally used in Asia for the treatment of dyspnea, cough, mouth dryness, spontaneous diaphoresis, nocturnal diaphoresis, nocturnal emission, dysentery, insomnia and amnesia. The purpose of this study is to evaluate the protective effects of Schisandra chinensis on oxidative DNA damage and lipid peroxidation induced by ROS in non cellular and cellular system. DPPH radical, hydroxyl radical and hydrogen peroxide scavenging assay were used to measure the antioxidant activities. Phi X-174RF I plasmid DNA cleavage assay and intracellular DNA migration assay were used to evaluate the protective effect on oxidative DNA damage. MTT assay and lipid peroxidation assay were used for evaluating the protective effect on oxidative cell damage. It was found to scavenge DPPH radical, hydrogen peroxide and hydroxyl radical and it inhibited oxidative DNA damage, lipid peroxidation and cell death induced by hydroxyl radical. These data indicate that Schisandra chinensis possesses a spectrum of antioxidant and DNA-protective properties

Sjögren's Syndrome: an Update on Diagnostic, Clinical, and Basic Aspects for Oral Medicine Specialists

  • Lee, Kyung-Eun
    • Journal of Oral Medicine and Pain
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    • v.43 no.4
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    • pp.99-111
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    • 2018
  • $Sj{\ddot{o}}gren^{\prime}s$ syndrome (SjS) is a common autoimmune disorder characterized by lymphocytic infiltration in the salivary and lacrimal glands, resulting in severe dry mouth or eyes. As a result, most of SjS patients suffer from oral dryness and can visit the department of oral medicine with or without diagnosis of SjS. Therefore, oral medicine specialists should know clues, which may indicate the diagnosis of SjS from the clinical and laboratory investigations. By the recent SjS criteria, SjS can be diagnosed by focus score, ocular staining, Schirmer's test, unstimulated whole saliva flow rate, and anti-SSA/Ro antibodies. The aim of this article is to review the diagnostic criteria, clinical investigation, and basic aspect related to SjS and to make oral medicine specialists play an important role in the detection of emerging SjS.

The Effect of Anticholinergic Agents on Postoperative Sore Throat in Patients Undergoing Endoscopic Sinus Surgery (내시경적 부비동 수술 시 항콜린성제제 사용이 수술 후 인후통 발생에 미치는 영향)

  • Lee, Joo-Young;Lee, Deok-Hee
    • Journal of Yeungnam Medical Science
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    • v.24 no.2
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    • pp.305-310
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    • 2007
  • Background : After sinus surgery, airway dryness is made worse because patients breathe by mouth. Anticholinergic agents have antisialogogue effects. The airway dryness that occurs after surgery is severe and can increase the incidence of postoperative sore throat. Materials and Methods : One-hundered patients who were scheduled for endoscopic sinus surgery(ESS) were divided into four groups. Each group was premedicated with glycopyrrolate or had no premedication and reversed with glycopyrrolate or atropine. After the surgery the patients were asked about a sore throat and hoarseness postoperatively after 1h, 6h, 12h, 24h, and 48hours, respectively. Results : The incidence of postoperative sore throat and hoarseness was not significantly different among the four groups at any time. Conclusion : The severity of complications after ESS was low and subsided within 24 hours. Therefore, the use of anticholinergic agents does not need to be limited.

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A Study on The Clinical Characteristics and Treatment in Burning Mouth Syndrome (구강 작엽감 증후군 (BMS)의 임상적 특징 및 치료에 관한 연구)

  • Mi-Jung Yeom;Chong-Youl Kim
    • Journal of Oral Medicine and Pain
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    • v.20 no.1
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    • pp.39-52
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    • 1995
  • Burning mouth syndrome is characterized by a burning sensation in oral cavity without clinical signs. There has b een no established theories about the diagnosis and treatment. The purpose of this article is to examine the clinical feature of BMS patients of Korean and to present a treatment protocol that can be helpful in clinical applications. The subjects chosen for the study were 52 patients who had visited Department of Oral Diagnosis at Yonsei University Dental Hospital and were diagnosed as BMS. We did questionnaires and precise oral exam, laboratory exam, grouping of our patients, individual treatment for the groups and classification of responses to the treatment. The following results were obtained: 1. Chief complaints were throbbing (71.2%), pricking, stinging, tingling (30.8%), burning(25a%). The tongue is the most frequently affected site (82.7%), followed by full mouth, gingiva, palate, buccal mucosa, lips, throat, labial mucosa and floor of mouth. 2. The average age of onset was 48.1 year and the male to female ratio was 1 to 3. The average duration of symptom was 11.69 months for male and 23.07 months for female. 3. 32.7% of patients had appealed continuous pain, which was the most cases. Aggravating factors were peppery food, salty food, hot food, fatigue, tension conversation, sour food, cold food and toothpaste. Reducing factors were cold food, diet, going to sleep and smoking. 4. Associated symptoms were dry mouth, other life problem, altered taste perception, bad taste, throat pain, tingle and difficulty in swallowing. 5. Most of patients had appealed that there was not associated event on onset of symptom, and the order of prevalence is as fallow; dental treatment, stress, denture wearing, an attack of a systemic disease. 92.3% of patient appealed that there was no psychological withering and 7.7% of patients appealed positively. 6. There were eight males and four females that had jobs. 7. There was no family history in 100% of patients in questions about presence of family history. 8. 96.2% of patients appealed that there was no oral habits. 13.5% of patients had dryness of oral mucosa in oral exam. A significant relation to dental prosthesis was not observable, but incidence of diseases due to stress appeared high in BMS which had the clinical characteristics as above. A group having low serum iron was 63.5% and in this group period of potential iron deficiency appeared high in incidence just before move to anemia. A group represented positive response was 38.5% in fungus study for Candida albicans. Since we can expect high treatment response by prescription of iron-contained drug and antifungal drug in these patients, diagnosing patients' condition of BMS can be achieved in more various aspects through study for serum iron and Candida albicans. Furthermore, it is expected that treatment protocol can be made.

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