• Title/Summary/Keyword: Morphogenesis

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Turing, Turing Instability, Computational Biology and Combustion (Turing, Turing 불안정성 그리고 수리생물학과 연소)

  • Kim, J.S.
    • Journal of the Korean Society of Combustion
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    • v.8 no.1
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    • pp.46-56
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    • 2003
  • The present paper is concerned with the development of the computational biology in the past half century and its relationship with combustion. The modem computational biology is considered to be initiated by the work of Alan Turing on the morphogenesis in 1952. This paper first touches the life and scientific achievement of Alan Turing and his theory on the morphogenesis based on the reactive-diffusive instability, called the Turing instability. The theory of Turing instability was later extended to the nonlinear realm of the reactive-diffusive systems, which is discussed in the framework of the excitable media by using the Oregonator model. Then, combustion analogies of the Turing instability and excitable media are discussed for the cellular instability, pattern forming combustion phenomena and flame edge. Finally, the recent efforts on numerical simulations of biological systems, employing the detailed bio-chemical knietic mechanism is discussed along with the possibility of applying the numerical combustion techniques to the computational cell biology.

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The Role of Cytoskeletal Elements in Shaping Bacterial Cells

  • Cho, Hongbaek
    • Journal of Microbiology and Biotechnology
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    • v.25 no.3
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    • pp.307-316
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    • 2015
  • Beginning from the recognition of FtsZ as a bacterial tubulin homolog in the early 1990s, many bacterial cytoskeletal elements have been identified, including homologs to the major eukaryotic cytoskeletal elements (tubulin, actin, and intermediate filament) and the elements unique in prokaryotes (ParA/MinD family and bactofilins). The discovery and functional characterization of the bacterial cytoskeleton have revolutionized our understanding of bacterial cells, revealing their elaborate and dynamic subcellular organization. As in eukaryotic systems, the bacterial cytoskeleton participates in cell division, cell morphogenesis, DNA segregation, and other important cellular processes. However, in accordance with the vast difference between bacterial and eukaryotic cells, many bacterial cytoskeletal proteins play distinct roles from their eukaryotic counterparts; for example, control of cell wall synthesis for cell division and morphogenesis. This review is aimed at providing an overview of the bacterial cytoskeleton, and discussing the roles and assembly dynamics of bacterial cytoskeletal proteins in more detail in relation to their most widely conserved functions, DNA segregation and coordination of cell wall synthesis.

DNA Coding Method for Evolution of Developmental Model (발생모델의 진화를 위한 DNA 코딩방법)

  • 심귀보;이동욱
    • Proceedings of the IEEK Conference
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    • 1999.06a
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    • pp.464-467
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    • 1999
  • Rapid progress in the modeling of biological structures and simulation of their development has occurred over the last few years. Cellular automata (CA) and Lindenmayer-system(L-system) are the representative models of development/morphogenesis of multicellular organism. L-system is applied to the visualization of biological plant. Also, CA are applied to the study of artificial life and to the construction of an artificial brain. To design the L-system and CA automatically, we make this model evolve. It is necessary to code the developmental rules for evolution. In this paper, we propose a DNA coding method for evolution the models of development/morphogenesis of biological multicellular organisms. DNA coding has the redundancy and overlapping of gene and is apt for the representation of the rule. In this paper, we propose the DNA coding method of CA and L-system.

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Several Genes Expressed During Morphogenesis of Lentinus edodes(ImHyup-1)

  • Lee, Sang-Sun;Hong, Sung-Woon;Kim, Seung-Hae;Kim, Bong-Cheol
    • Mycobiology
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    • v.29 no.3
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    • pp.135-141
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    • 2001
  • Differential display of reverse transcription(DDRT)-PCR was conducted to have a profile of the differentially expressed genes during the formation of fruiting body of Lentinus edodes. The lines of L. edodes(ImHyup-1) employed were cultivated in the artificial blocks of sawdust, and the fruiting body was induced from the mycelia or the mass protruded from the brown surface of the sawdust blocks. RNAs were prepared from the four different developmental stages; mycelial, primordial, and stipes and pileus of fruiting body. The fragments of cDNA were synthesized from the combinations of the arbitrary primers and 3' one anchored Oligo-dT primer. Twelve combinations using the primers have been tested, and among them nineteen bands were identified as differentially expressed. Those genes were further analyzed by DNA sequencing and followed by homology search. Characterization of one clone was conducted as a preliminary data and more are under investigation.

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Genome Organization of Temperate Phage 11143 from Emetic Bacillus cereus NCTC11143

  • Lee, Young-Duck;Park, Jong-Hyun
    • Journal of Microbiology and Biotechnology
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    • v.22 no.5
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    • pp.649-653
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    • 2012
  • A temperate phage was isolated from emetic Bacillus cereus NCTC 11143 by mitomycin C and characterized by transmission electron microscopy and DNA and protein analyses. Whole genome sequencing of Bacillus phage 11143 was performed by GS-FLX. The phage has a dsDNA genome of 39,077 bp and a 35% G+C content. Bioinformatic analysis of the phage genome revealed 49 putative ORFs involved in replication, morphogenesis, DNA packaging, lysogeny, and host lysis. Bacillus phage 11143 could be classified as a member of the Siphoviridae family by morphology and genome structure. Genomic comparisons at the DNA and protein levels revealed homologous genetic modules with patterns and morphogenesis proteins similar to those of other Bacillus phages. Thus, Bacillus phages might have a mosaic genetic relationship.

Early Stages in Morphogenesis of the Shell of Crenella decussata (Bivalvia: Mytilidae)

  • Kolotukhina, N.K.;Kulikova, V.A.;Evseev, G.A.
    • The Korean Journal of Malacology
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    • v.27 no.2
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    • pp.91-97
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    • 2011
  • This study examines the morphological features of larval and postlarval shells of the paedomorphic bivalve Crenella decussata Montagu, 1808 from the Sea of Japan. During the early morphogenesis of the shell of C. decussata the following characteristics appear: prodissoconch I -the anterior and posterior provincular teeth, a broad primary ligament pit located on the chondrophore; nepioconch - the anterior and posterior juvenile teeth,primary lateral teeth, fine commarginal and radial sculpture. Larvae of C. decussata distinctly differ from other mytilid larvae by a D-shaped shell, absence of umbo, astraight hinge margin, and homogeneous fine-grained sculpture without co-marginal lines of growth. These shell characters indicate lecithotrophic development of this species. Some morphostructures are revealed which might be used in crenellin taxonomy.

Shape Creation of Spatial Structures using L-system Model (L-system 모델을 이용한 대공간 구조물의 형태생성 방안)

  • Kim, Ho-Soo;Park, Young-Sin;Lee, Min-Ho;Han, Chol-Hee
    • Journal of Korean Association for Spatial Structures
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    • v.11 no.3
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    • pp.125-135
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    • 2011
  • This study presents the shape creation process using L-system model of morphogenesis technique. In general, L-system model has been applied to represent the visualization of biological plant. But, this study proposes the shape generation process of L-system model to apply the architectural field. The L-system model consists of two parts such as string generation step and string analysis step. The string generation step shows the process for a string rewriting. This step requires alphabet, axiom and rules to generate a string. Also, the string analysis step gives the meaning in string to generate various forms. Especially, through the various application examples, we can find out the shape creation models for the space structures.