• Title/Summary/Keyword: Modified IPA

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Improvement of Rheological and Functional Properties of Salmon FPC by Enzymatic Partial Hydrolysis 1. Production of Salmon FPC Hydrolysates and Their General Properties (효소적 부분 가수분해에 의한 연어 FPC(Fish Protein Concentrates)의 물성 및 기능성 개선 1. 연어 FPC의 가수분해물 제조와 일반적인 성상)

  • LEE Jong-Ho;LEE Keun-Tai;PARK Seong-Min;PARK Chan-kyu
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.1
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    • pp.132-138
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    • 1998
  • To improve functional properties and enhance application of FPC in food industry, modified salmon FPC with enzyme treatment was produced and its general properties were investigated. Salmon FPC has over $84\%$ of protein and less than $0.18\%$ of lipid. Solubilities of FPC extracted with IPA and ethanol were very poor as less than $3\%$ in every pH range. In case of enzyme : substrate ratio of 1 : 100, degree of hydrolysis significantly increased until 4 hours and then slightly increased. No considerable differences were observed in general components of hydrolysates. Results of SDS-PAGE showed one unique band in each case and their molecular weight was less than 6,500. The flow properties of hydrolysates showed newtonian flow. Whiteness of hydrolysates were higher than that of salmon FPC as $5\~7$. There was no significant differences in the amount of peptide, but that of free amino acid slightly increased from 0.17 to 0.21 mg/ml.

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Differential Expression of Gene Profiles in MRGX-treated Lung Cancer

  • Kwon, Yong-Kyun;Lee, Seung-Yeul;Kang, Hwan-Soo;Sung, Jung-Suk;Cho, Chong-Kwan;Yoo, Hwa-Seung;Shin, Seungjin;Choi, Jong-Soon;Lee, Yeon-Weol;Jang, Ik-Soon
    • Journal of Pharmacopuncture
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    • v.16 no.3
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    • pp.30-38
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    • 2013
  • Objectives: Modified regular ginseng extract (MRGX) has stronger anti-cancer activity-possessing gensenoside profiles. Methods: To investigate changes in gene expression in the MRGX-treated lung cancer cells (A549), we examined genomic data with cDNA microarray results. After completing the gene-ontology-based analysis, we grouped the genes into up-and down-regulated profiles and into ontology-related regulated genes and proteins through their interaction network. Results: One hundred nine proteins that were up- and down-regulated by MRGX were queried by using IPA. IL8, MMP7 and PLAUR and were found to play a major role in the anti-cancer activity in MRGX-treated lung cancer cells. These results were validated using a Western blot analysis and a semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) analysis. Conclusions: Most MRGX-responsive genes are up-regulated transiently in A549 cells, but down-regulated in a sustained manner in lung cancer cells.

The Importance-Performance Analysis of Bakery Cafe Choice Attributes Perceived by Customers in Seoul (베이커리카페 선택속성의 중요도 및 수행도 분석: 서울지역을 중심으로)

  • Choi, Mi-Kyung;Jung, Jae-Chan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.4
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    • pp.456-463
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    • 2006
  • The purposes of this study were to extract choice attributes of bakery cafe customers and to conduct important- performance analysis (IPA) of choice attributes perceived by bakery cafe customers. The questionnaire was developed through literature review and focus group interview, and modified after pilot test. The questionnaires for main survey were distributed to 320 males and females aged 20 and over in Seoul. A total of 275 questionnaires were used for analysis (85.9%) and the statistical analyses were conducted using SPSS Win (12.0) for descriptive analyses, exploratory factor analysis, reliability analysis, and correlation analyses. The main results were as follows. 'Products', 'convenience to use', 'services and price', 'interior environments' 'brand' and 'location' dimensions were extracted as choice attributes dimensions of bakery cafe customers and customers of bakery cafe regarded 'sanitation and cleanness', 'kindness of employees', 'quality of products', 'comfortable and pleasant facilities' and 'taste of bakery products' as more important than other attributes. In addition, the results of IPA showed that marketing managers of bakery cafes should focused on the dimension of 'services and price' in the reason that this dimension was low at performance although customers regarded it very important. Overall, researchers and managers of bakery cafes should understand unique choice attributes of bakery cafe customers, and make efforts to establish marketing strategies that meet bakery cafe customers' needs.

Checklist for the application of concurrent engineering in bridge construction (교랑 공사에 동시공학 적용을 위한 체크리스트 도출)

  • Park, Seaman;Park, Taeil;Kim, Hyoungkwan
    • Korean Journal of Construction Engineering and Management
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    • v.14 no.1
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    • pp.3-11
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    • 2013
  • As construction projects became larger and longer, the need for the construction technologies and innovative construction processes has been continuously increased in construction field. In response to this trend, construction industries tried to adopt the concurrent engineering which had been normally applied for manufacturing industries to develop the products with improved quality in a reduced time. However, the application of the concurrent engineering to construction field was limited due to the lack of advanced management system and incomplete theoretical backgrounds. In this regard, this study attempted to develop a checklist for the successful application of concurrent engineering to bridge projects. To this end, this study presents the checklist for the application of concurrent engineering to construction projects. Further, the checklist was modified and updated to reflect the specific feature of the bridge construction using expert interviews. With the help of additional 188 experts, a questionnaire-based survey was also conducted to validate the checklist. In addition, using importance-performance analysis(IPA), the study identified the factors needed for intensive improvement. Consequently, the proposed checklist is expected to be useful, because it improves the applicability of the concurrent engineering in that it enables managers to monitor construction progress and further to protect the project from potential risks.

The Effects of Dramatherapy Program on Sociality of Isolated Children (연극치료 프로그램이 고립아동의 사회성에 미치는 효과)

  • Ahn, Tae-Yong
    • The Korean Journal of Elementary Counseling
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    • v.6 no.1
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    • pp.117-140
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    • 2007
  • This study is to know the effect of drama therapy on the sociality of isolated children. To achieve this goal, the following hypothesis was built. Hypothesis I. Dramatherapy program will improve the sociality of isolated children. I -1. Dramatherapy program will improve in cooperation. I -2. Dramatherapy program will improve in independency. I -3. Dramatherapy program will improve in sociability. I -4. Dramatherapy program will improve in law-abiding. To test this hypothesis, the social and emotional isolation test was conducted in 190 children consisting of fifth-grader from N elementary school located in Busan to select 28 children whose founded to be isolated; among these children, eight who wanted to participate in the program were positioned at the experimental group and other eight who didn't want to do and who demonstrated the range of marks similar to the experimental group were positioned at the control group. The dramatherapy program was based on the theory by Robert Landy (2002), Jennings (2003) and Phil Jones (2005) to improve the sociality of isolated children and was implemented in a total of 15 sessions, two sessions a week after school. To test the effect of the program, A modified test paper by Suh, Poongyeon (1991) with the content of testing sociality into a test paper of human nature for elementary school students to be made by Jeong, Bummo (1971) was used which consists of four sub-factors: cooperation, independency, sociability, law-abiding. As a quantitative analysis, Mann-Whitney Test were analyzed for experimental and control groups. As a qualitative analysis, the interaction patterns among student were analyzed on he basis of video tapes. The tool of observe the interaction patterns among student was Interaction Process Analysis System which was made by Bales (1970). This study obtained the following result First, the drama therapy had meaningful effect on the sociality of the sociality of isolated children. But the quantitative change of the sociality test conclusion was showed meaningfully and positive social behavior was increased in periodical process analysis. Second, in the Interaction Process Analysis(IPA) affirmative interactions increased and negative interactions decreased.

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Owner-driven Lean Construction based on Participants' Needs Analysis (건설주체간의 니즈분석을 통한 발주자 참여형 린 건설 연구)

  • Lee, Kang-Woo;Ryu, Chung-Gyu;Park, Hee-Dae;Han, Seung-Heon
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2008.11a
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    • pp.222-226
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    • 2008
  • The construction industry has remained stagnant for a long time. So many researchers have wanted to solve this problem not only focusing on enhancement of construction process, but also introducing the culture of cooperation. The Last Planner System(LPS), one of the elementary techniques of Lean Construction, aims for improving the work reliability and reducing variability by measuring and managing the daily or weekly performance for overcoming the weakness of recent complex schedule management tools such as Critical Path Method. This research propose a framework for implementation of LPS conducted by owner focused on construction stage and introduce optimal owner participation model in plant construction, based on needs analysis for construction participants. Furthermore, this research introduce a modified needs analysis, so called IPBA(Importance-Performance-Betterment Analysis), and an advanced LPS procedure which add the needs analysis during pre-LPS and(or) main LPS stages.

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