• Molecules and Cells
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• v.42 no.7
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• pp.503-511
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• 2019

As sessile organisms, plants have developed sophisticated system to defend themselves against microbial attack. Since plants do not have specialized immune cells, all plant cells appear to have the innate ability to recognize pathogens and turn on an appropriate defense response. The plant innate immune system has two major branches: PAMPs (pathogen associated molecular patterns)-triggered immunity (PTI) and effector-triggered immunity (ETI). The ability to discriminate between self and non-self is a fundamental feature of living organisms, and it is a prerequisite for the activation of plant defenses specific to microbial infection. Arabidopsis cells express receptors that detect extracellular molecules or structures of the microbes, which are called collectively PAMPs and activate PTI. However, nucleotidebinding site leucine-rich repeats (NB-LRR) proteins mediated ETI is induced by direct or indirect recognition of effector molecules encoded by avr genes. In Arabidopsis, plasmamembrane localized multifunctional protein RIN4 (RPM1-interacting protein 4) plays important role in both PTI and ETI. Previous studies have suggested that RIN4 functions as a negative regulator of PTI. In addition, many different bacterial effector proteins modify RIN4 to destabilize plant immunity and several NB-LRR proteins, including RPM1 (resistance to Pseudomonas syringae pv. maculicola 1), RPS2 (resistance to P. syringae 2) guard RIN4. This review summarizes the current studies that have described signaling mechanism of RIN4 function, modification of RIN4 by bacterial effectors and different interacting partner of RIN4 in defense related pathway. In addition, the emerging role of the RIN4 in plant physiology and intercellular signaling as it presents in exosomes will be discussed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.9
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• pp.1173-1178
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• 2019

In this paper, we design a security management application module for an Excel VBA password file. You will set a password for the important VBA program file. If this password is lost, you set a new password. If you forgot the password after setting the password in the Excel VBA file, you will not be able to change the VBA source code. In this paper, we design a function to modify VBA file passwords conveniently. The VBA password modification module extracts VBA files from Excel files. The password can be modified by modifying specific field information in the extracted VBA program file. This allows you to modify the password for the VBA program file. The experiments were performed by implementing the contents proposed in this paper. As a result of the experiment, we can confirm that the password can be used by modifying the VBA file password.

• Biomaterials Research
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• v.22 no.4
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• pp.346-351
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• 2018

Background: Carbonate apatite ($CO_3Ap$) and silica-calcium phosphate composite (SCPC) are bone substitutes with good prospect for dental application. SCPC creates a hydroxyapatite surface layer and stimulate bone cell function while, $CO_3Ap$ induce apatite crystal formation with good adaptation providing good seal between cement and the bone. Together, these materials will add favorable properties as a pulp capping material to stimulate mineral barrier and maintain pulp vitality. The aim of this study is to investigate modification of $CO_3Ap$ cement combined with SCPC, later term as $CO_3Ap-SCPC$ cement (CAS) in means of its chemical (Calcium release) and physical properties (setting time, DTS and pH value). Methods: The study consist of three groups; group 1 (100% calcium hydroxide, group 2 $CO_3Ap$ (60% DCPA: 40% vaterite, and group 3 CAS (60% DCPA: 20% vaterite: 20% SCPC. Distilled water was employed as a solution for group 1, and $0.2mol/L\;Na_3PO_4$ used for group 2 and group 3. Samples were evaluated with respect to important properties for pulp capping application such as pH, setting time, mechanical strength and calcium release evaluation. Results: The fastest setting time was in $CO_3Ap$ cement group without SCPC, while the addition of 20% SCPC slightly increase the pH value but did not improved the cement mechanical strength, however, the mechanical strength of both $CO_3Ap$ groups were significantly higher than calcium hydroxide. All three groups released calcium ions and had alkaline pH. Highest pH level, as well as calcium released level, was in the control group. Conclusion: The CAS cement had good mechanical and acceptable chemical properties for pulp capping application compared to calcium hydroxide as a gold standard. However, improvements and in vivo studies are to be carried out with the further development of this material.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.35 no.5
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• pp.431-438
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• 2022

In functional materials, in situ experimental techniques as a function of external stimulus (e.g., electric field, magnetic field, light, etc.) or changes in ambient environments (e.g., temperature, humidity, pressure, etc.) are highly essential for analyzing how the physical properties of target materials are activated/evolved by the given stimulation. In particular, in situ electric-field-dependent X-ray diffraction (XRD) measurements have been extensively utilized for understanding the underlying mechanisms of the emerging electromechanical responses to external electric field in various ferroelectric, piezoelectric, and electrostrictive materials. This tutorial article briefly introduces basic principles/key concepts of in situ electric-field-dependent XRD analysis using a lab-scale XRD machine. We anticipate that the in situ XRD method provides a practical tool to systematically identify/monitor a structural modification of various electromechanical materials driven by applying an external electric field.

• Molecules and Cells
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• v.45 no.9
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• pp.660-672
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• 2022

The target of rapamycin complex (TORC) plays a key role in plant cell growth and survival by regulating the gene expression and metabolism according to environmental information. TORC activates transcription, mRNA translation, and anabolic processes under favorable conditions, thereby promoting plant growth and development. Tomato fruit ripening is a complex developmental process promoted by ethylene and specific transcription factors. TORC is known to modulate leaf senescence in tomato. In this study, we investigated the function of TORC in tomato fruit ripening using virus-induced gene silencing (VIGS) of the TORC genes, TOR, lethal with SEC13 protein 8 (LST8), and regulatory-associated protein of TOR (RAPTOR). Quantitative reverse transcription-polymerase chain reaction showed that the expression levels of tomato TORC genes were the highest in the orange stage during fruit development in Micro-Tom tomato. VIGS of these TORC genes using stage 2 tomato accelerated fruit ripening with premature orange/red coloring and decreased fruit growth, when control tobacco rattle virus 2 (TRV2)-myc fruits reached the mature green stage. TORC-deficient fruits showed early accumulation of carotenoid lycopene and reduced cellulose deposition in pericarp cell walls. The early ripening fruits had higher levels of transcripts related to fruit ripening transcription factors, ethylene biosynthesis, carotenoid synthesis, and cell wall modification. Finally, the early ripening phenotype in Micro-Tom tomato was reproduced in the commercial cultivar Moneymaker tomato by VIGS of the TORC genes. Collectively, these results demonstrate that TORC plays an important role in tomato fruit ripening by modulating the transcription of various ripening-related genes.

• Journal of the Korea Society of Computer and Information
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• v.27 no.12
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• pp.179-188
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• 2022

In this paper, we propose an efficient and procedural software patch management phases. Every year, organizations have tens of thousands of known vulnerabilities and spend tens of thousands of hours and millions of dollars or more patching them. Despite these efforts, research has shown that the time it takes for an exploit to appear for a given patched vulnerability is shortening. As various types of organizations such as companies and universities manage patches in inconsistent ways, problems such as security problems, system instability, information leakage and work delay due to patches occur. In this paper, we look at the basics required for software patch management and define the factors to be considered for patch management and the effective steps for patch management. Therefore, this study will be used as a method to efficiently and procedurally execute the organization's patch management policy in the process of updating and patching the software in the organization to a new version as a solution to software function modification and security vulnerability.

• Journal of Korea Port Economic Association
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• v.38 no.2
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• pp.1-10
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• 2022

Looking at the cargo trend of Gwangyang port (GWP) during past decade, petrochemical items grew by 26% and steel item grew by 12%, but container cargo just grew by 4%. Thus, Yeosu-Gwangyang Port Authority (YGPA) sets the port development initiative targeting at industrial core port considering GWP's strength as multi function port and industrial port and GWP's weakness as lower container cargo growth trend. The purpose of this study is proposing the projects about the GWP's industrial core port development. The results of the study is as follows. As a prerequisite for development as an industrial core port, it was suggested to form a consensus on the modification or change of the port performance index of univariate port cargo volume. The following three tasks were presented for GWP to develop as an industrial core port. It can be said that it is most necessary to derive, manage, and monitor GWP industrial core performance indicators. Next, it is necessary to conduct a survey on the satisfaction of industrial support in ports. Finally, it is necessary to measure the added value of the port area of GWP hinterland.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.871-874
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• 2011

The fast emerging of network technology and the high demand of computing resources have prompted many organizations to outsource their storage and computing needs. Cloud based storage services such as Microsoft's Azure and Amazon's S3 allow customers to store and retrieve any amount of data, at anytime from anywhere via internet. The scalable and dynamic of the cloud storage services help their customer to reduce IT administration and maintenance costs. No doubt, cloud based storage services brought a lot of benefits to its customer by significantly reducing cost through optimization increased operating and economic efficiencies. However without appropriate security and privacy solution in place, it could become major issues to the organization. As data get produced, transferred and stored at off premise and multi tenant cloud based storage, it becomes vulnerable to unauthorized disclosure and unauthorized modification. An attacker able to change or modify data while data inflight or when data is stored on disk, so it is very important to secure data during its entire life-cycle. The traditional cryptography primitives for the purpose of data security protection cannot be directly adopted due to user's lose control of data under off premises cloud server. Secondly cloud based storage is not just a third party data warehouse, the data stored in cloud are frequently update by the users and lastly cloud computing is running in a simultaneous, cooperated and distributed manner. In our proposed mechanism we protect the integrity, authentication and confidentiality of cloud based data with the encrypt- then-upload concept. We modified and applied proxy re-encryption protocol in our proposed scheme. The whole process does not reveal the clear data to any third party including the cloud provider at any stage, this helps to make sure only the authorized user who own corresponding token able to access the data as well as preventing data from being shared without any permission from data owner. Besides, preventing the cloud storage providers from unauthorized access and making illegal authorization to access the data, our scheme also protect the data integrity by using hash function.

• Molecules and Cells
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• v.46 no.6
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• pp.351-359
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• 2023

Deamination of adenine or cytosine in RNA, called RNA editing, is a constitutively active and common modification. The primary role of RNA editing is tagging RNA right after its synthesis so that the endogenous RNA is recognized as self and distinguished from exogenous RNA, such as viral RNA. In addition to this primary function, the direct or indirect effects on gene expression can be utilized in cancer where a high level of RNA editing activity persists. This report identified actin-related protein 2/3 complex inhibitor (ARPIN) as a target of ADAR1 in breast cancer cells. Our comparative RNA sequencing analysis in MCF7 cells revealed that the expression of ARPIN was decreased upon ADAR1 depletion with altered editing on its 3'UTR. However, the expression changes of ARPIN were not dependent on 3'UTR editing but relied on three microRNAs acting on ARPIN. As a result, we found that the migration and invasion of cancer cells were profoundly increased by ADAR1 depletion, and this cellular phenotype was reversed by the exogenous ARPIN expression. Altogether, our data suggest that ADAR1 suppresses breast cancer cell mobility via the upregulation of ARPIN.

• Textile Coloration and Finishing
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• v.35 no.4
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• pp.239-245
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• 2023

Cellulose is an abundant biodegradable material in nature with excellent properties, but due to its poor processability, it has been widely studied for processing through modification. Cellulose acetate propionate (CAP) is a cellulose derivative in which the hydroxyl group of cellulose is replaced by acetyl and propionyl groups. CAP has several advantages, such as excellent solubility, structural stability, light and weather resistance, and good transparency. Porous nanofibers with excellent specific surface area, which can be applied in various fields, can be easily formed by the phase separation method using highly volatile solvents. High speed centrifugal spinning is a nano/micro fiber preparation method with advantages such as fast spinning and easy alignment control. In this study, a CAP/polybutylene succinate (PBS) spinning solution with chloroform as solvent was prepared to prepare porous microfibers and the fiber morphology was examined as a function of the disk rotation speed in an high speed centrifugal spinning device.