• The Korean Journal of Physiology and Pharmacology
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• 제24권6호
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• pp.529-543
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• 2020

In contrast to ventricular myocytes, the structural and functional importance of atrial transverse tubules (T-tubules) is not fully understood. Therefore, we investigated the ultrastructure of T-tubules of living rat atrial myocytes in comparison with ventricular myocytes. Nanoscale cell surface imaging by scanning ion conductance microscopy (SICM) was accompanied by confocal imaging of intracellular T-tubule network, and the effect of removal of T-tubules on atrial excitation-contraction coupling (EC-coupling) was observed. By SICM imaging, we classified atrial cell surface into 4 subtypes. About 38% of atrial myocytes had smooth cell surface with no clear T-tubule openings and intracellular T-tubules (smooth-type). In 33% of cells, we found a novel membrane nanostructure running in the direction of cell length and named it 'longitudinal fissures' (LFs-type). Interestingly, T-tubule openings were often found inside the LFs. About 17% of atrial cells resembled ventricular myocytes, but they had smaller T-tubule openings and a lower Z-groove ratio than the ventricle (ventricular-type). The remaining 12% of cells showed a mixed structure of each subtype (mixed-type). The LFs-, ventricular-, and mixed-type had an appreciable amount of reticular form of intracellular T-tubules. Formamide-induced detubulation effectively removed atrial T-tubules, which was confirmed by both confocal images and decreased cell capacitance. However, the LFs remained intact after detubulation. Detubulation reduced action potential duration and L-type Ca²⁺ channel (LTCC) density, and prolonged relaxation time of the myocytes. Taken together, we observed heterogeneity of rat atrial T-tubules and membranous ultrastructure, and the alteration of atrial EC-coupling by disruption of T-tubules.

• 한국지진공학회논문집
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• 제5권5호
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• pp.73-83
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• 2001

상부벽식-하부골조구조(복합구조)는 상.하부 구조물의 서로 다른 구조형식으로 인해 전이층 부근에서 질량 및 강성의 큰 차이를 보인다. 이러한 복합구조의 특징은 일반적으로 강성, 질량 및 기하학적 수직 비정형성을 갖게 된다. 본 연구에서는 복합구조물의 상부층수가 변화하는 네 가지 해석모델을 선정하여 탄소성 정적 및 동적 해석을 수행하고 해석결과를 통해 구조물의 탄소성 응답특성을 살펴보고자 한다. 본 연구의 결론은 다음과 같다. 1) 탄소성 정적해석에서는 하부골조 구조의 보와기둥의 항복힌지가 상부벽식구조의 층수 변화에 상관없이 전 모델에 걸쳐 비슷한 크기의 설계용 밑면전단력에서 항복이 발생되었고 그 분포 또한 비슷하였다. 그러나 상부벽식구조의 경우 전단벽이 고층화될수록 coupling beam에서 설계용 밑면전단력 V에 대해서도 휨항복한지가 발생되었다. 2) 탄소성 동적해석으로부터는 하부골조의 일부층의 보는 55gal의 작은 지진동에서 소성이 발생되었고 상부벽식구조의 경우 coupling beam과 전이층 상부의 전단벽에서 소성변형이 집중되었다. 3) 탄소성 해석으로부터 상부벽식구조의 층수가 낮아질수록 하부골조구조의 층강성이 상대적으로 줄어들게 되어 하부골조에서 연약층(soft story) 현상이 나타났다.

• Elastomers and Composites
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• 제51권2호
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• pp.81-92
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• 2016

1,3-Diphenylguanidine (DPG) is commonly used as a secondary accelerator which not only acts as booster of cure but also activating silanization reaction. The aim of this study is to increase the interaction between silica and rubber by using DPG. In this study, mixing was proceeded in two steps. The T-1 compound is mixed DPG with silica and silane coupling agent in the kneader at high temperature which is named as $1^{st}$ mixing step. T-3 compound is mixed DPG with curatives in the two-roll mill at low temperature which is named as $2^{nd}$ mixing step. The T-2 compound is mixed a half of DPG in $1^{st}$ mixing step and the remainder is mixed in $2^{nd}$ mixing step. Total DPG content was equal for all compounds. When DPG is mixed with silica, silane coupling agent during the $1^{st}$ mixing step, a decrease in cure rate and an increase in scorch time can be seen. This indicates that DPG is adsorbed on the surface of silica. during rubber processing. However, bound rubber content is increased and dynamic properties are improved. These results are due to the highly accelerated silanization reaction. However, there are no significant difference in 100%, 300% modulus.

• Journal of information and communication convergence engineering
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• 제14권4호
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• pp.268-271
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• 2016

An efficient inductive switching noise suppression technique for mixed-signal integrated circuits (ICs) using standard CMOS digital technology is proposed. The proposed design technique uses a parallel RC circuit, which provides a damping path for the switching noise. The proposed design technique is used for designing a mixed-signal circuit composed of a ring oscillator, a digital output buffer, and an analog noise sensor node for $0.13-{\mu}m$ CMOS digital IC technology. Simulation results show a 47% reduction in the on-chip inductive switching noise coupling from the noisy digital to the analog blocks in the same substrate without an additional propagation delay. The increased power consumption due to the damping resistor is only 67% of that of the conventional source damping technique. This design can be widely used for any kind of analog and high frequency digital mixed-signal circuits in CMOS technology

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
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• pp.1390-1393
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• 2006

The transmittance of bare glass was enhanced up to about 20% by coating it with a PMMA (Poly Methyl Meta Acrylate) film mixed with silica gel. This lowrefractive- index film greatly reduces total reflection inevitable for bare glass, and thus will be useful for increasing the coupling-out efficiency of OLED.

• 대한전자공학회논문지TC
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• 제39권1호
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• pp.49-57
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• 2002

이 논문에서는 패키지 인덕턴스를 고려한 다중 단자에서의 전도성 실리콘 기판에서의 커플링을 모델링하고 정량적으로 특성화한다. 이것을 위해 2단자 커플링 모델로부터 추출할 수 있는 모델 파라미터를 일반적인 구조에 적용할 수 있도록 개선하였다. 그리고 다중 단자의 노이즈 소스에 의한 기판 커플링 특성을 위해 기판의 주파수 의존적인 특성을 정확히 반영하는 2단자 기판 커플링 모델을 선형적으로 결합함으로써 일반적인 구조에 적용될 수 있도록 확장하였다. 또한 패키지 인덕턴스는 시스템의 특성 주파수를 높은 주파수 영역으로 이동시킴으로써 결과적으로 기판 커플링을 증가시키므로 정확한 분석이 요구된다. 따라서 기판 커플링 모델에 패키지 인덕턴스 성분을 추가하고 이를 정량적으로 분석함으로써 설계 초기 단계에서 패키지의 영향과 기판 커플링의 영향을 동시에 고려한 회로 성능 분석이 가능하도록 하였다. 그러므로 이 논문에서 제안한 방법은 복잡한 혼성 신호 회로의 성능 분석에 매우 유용하게 이용될 수 있다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1994년도 추계학술대회 논문집
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• pp.13-16
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• 1994

In this paper, xPb(Zn$_{1/3}Nb_{2/3}$)$O_3$-yPbTiO$_3$-zPbZrO$_3$-(0.5wt%)MnO$_2$ ceramics were fabricated by the mixed oxide method sintered at $1250^{\circ}C$ for 2[hr] and then the deielectric, electromechanical coupling factor($K_{p}$ and mechanical coupling factor(Qm) properties were investigated. In 0.1PZN-0.45PT-0.45PZsample, dielectric properties and electromechanical coupling factor were 829 and 29%. In the case of 0.5PZN-0.45PT-0.50PZ sample, that was 101 according to mechanical quality facotr. molphotropic phase boundary(MPB) certained area which $PbTiO_3$addition quatity 40∼50[㏖%].

• 한국전기전자재료학회논문지
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• 제22권11호
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• pp.930-934
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• 2009

In this study, in order to develop excellent lead-free composition ceramics for piezoelectric transformer, ($K_4CuNb_8O_{23}$) added $(K_{0.5}Na_{0.5})(Nb_{0.96}Sb_{0.04})O_3$ ceramics were fabricated using conventional mixed oxide method and their piezoelectric and dielectric properties were investigated as a fu+EY50nction of the amount of KCN addition. With increasing the amount of KCN addition, density and mechanical quality factor(Qm), electromechanical coupling factor (Kp) were increased up to 1.2 mol% and then decreased. At the 1.2 mol% KCN added specimen, mechanical quality factor (Qm), electromechanical coupling factor (Kp), density and dielectric constant (${\varepsilon}r$) showed the optimal values of 781, 0.445, $4.42\;g/cm^3$ and 443, respectively, for piezoelectric transformer application.

• Elastomers and Composites
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• 제43권4호
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• pp.230-240
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• 2008

분산중합법에 의해 무기물을 포함하는 고분자 미립자를 합성하기 위해 styrene과 n-butyl methacrylate가 알루미나와 함께 중합되었다. Styrene과 n-butylmethacrylate의 무게 비는 3:1이었고, 입자안정제는 poly(N-vinyl pyrrolidon), 중합 개시제로는 2,2'-azobis(isobutyronitrile)를 사용하여 개시제의 농도, 분산매의 종류, 분산매의 혼합 용해도 상수 (${\delta}_{mix}$), 커플링제의 종류와 농도에 따른 입자경을 조사하였다. 개시제의 농도가 증가함에 따라 입자경이 소폭 상승하였고 분산매의 극성이 증가할수록 입경이 증가하였고, 분산매로서, 이소프로판올과 이온교환수를 조성비에 따라 사용한 경우, $[{\delta}_{mix}]^{-4.01}\;{\propto}$ 평균 입자경과 $[{\delta]_{mix}]^{-0.83}\;{\propto}$ 입경 분포의 관계를 얻을 수 있었다. 커플링제의 종류와 농도변화에 따른 입자경 및 입자경 분포는 뚜렷한 차이가 없었다.

• Bulletin of the Korean Chemical Society
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• 제21권10호
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• pp.969-972
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• 2000

[Fe II Fe III $BPLNP(OAc)_2](BPh_4)_2$ (1), a new model for the reduced form of the purple acid phosphatases, has been synthesized by using a dinucleating ligand, 2,6-bis[((2-pyridylmethyl)(6-methyl-2-pyridylmethyl)ami-no)methyl]-4-nitrophenol (HBPLNP) . Complex 1 has been studied by electronic spectral, NMR, EPR, SQUID, and electrochemical methods. Complex 1 exhibits two strong bands at 498 nm $(\varepsilon=$ 2.6 ${\times}10^3M-^1cm-^1)$ and 1363 nm $(\varepsilon=$ 5.7 ${\times}10^2M-^1cm-^1)$ in $CH_3CN.$ These are assigned to phenolate-to-FeIII and intervalence charge-transfer transitions, respectively. NMR spectrum of complex 1 exhibits sharp isotropically shifted resonances, which number is half of those expected for a valence-trapped species, indicating that electron transfer between FeⅡ and FeⅢ centers is faster than NMR time scale at room temperature. Complex 1 undergoes quasireversible one-electron redox processes. The $FeIII_2/FeIIFeIII$ and $FeIIFeIII/FeII_2$ redox couples are at 0.807 and 0.167 V ver-sus SCE, respectively. It has Kcomp = 5.9 ${\times}$10 1s(acetato) ligand combination sta-bilizes a mixed-valence FeIIFeIII complex in the air. Interestingly, complex 1 exhibits intense EPR signals at g = 8.56, 5.45, 4.30 corresponding to mononuclear high-spin FeⅢ species, which suggest a very weak magnetic coupling between the iron centers. Magnetic susceptibility study shows that there is a very weak antiferromag-netic coupling (J = $-0.78cm-^1$, H = $-2JS_1${\times}$S_2)$ between FeII and FeIII centers. Thus, we can suggest that complex 1 has a very weak antiferromagnetic coupling between the iron centers due to the electronic effect of the nitro group in the bridging phenolate ligand.