• Journal of the Korean Institute of Intelligent Systems
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• v.27 no.2
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• pp.113-118
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• 2017

Various studies on the method of ship collision risk assessment for alarm have been reported constantly, and the result of the studies is applied to navigation devices. However, it is known that navigators ignore or turn off frequent alarms from the devices of predicting collision risk, because they may avoid collisions in the most of situations. In oder to make the prediction of ship collision risk more useful, it is necessary to consider the customary actions of ship collision avoidance. This paper proposes a system of analyzing collision avoidance measures of ships according to the types of encounter and managing the avoidance history of each ship. The core module of the system is designed as a neuro-fuzzy based inference system, and the test of the module validates the proposed system.

• Journal of the Korean housing association
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• v.25 no.4
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• pp.31-38
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• 2014

The present research aimed at researching the relationships among place attachment, residential evaluations and satisfaction in a medium-sized post-communist Romanian city. Studies on post-communist cities are scarce and this research tried to fill that gap. This research is part of a government project that intended to significantly reform three medium-sized cities in the Western part of Romania and transform the urban space. Since the three of them are relatively small-sized and close spatially, the project intends to undertake massive reforms of the communications and services of the three cities. In this article, we report findings on the city of Hunedoara. A representative random sample was selected, and a total of 384 people were interviewed, with an overall reliability of the sample of 95%. The instruments used to gather the data were the Neighbourhood Perceived Environmental Quality Scale and a composite measure of place attachment was also included. The structure of each scale was checked using exploratory factor analysis. We tested alternative causal models using structural equations modelling. Our model showed a good fit to the data and explains satisfaction in the city adequately. Results show that satisfaction is directly predicted by the general evaluation of the city and by residential privacy. Residential noise and place attachment influence satisfaction indirectly. The results are discussed and some policy recommendations are formulated.

• The Journal of the Acoustical Society of Korea
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• v.37 no.3
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• pp.129-138
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• 2018

In port and coastal areas where ship traffic is frequent, ship noise dominantly influences underwater noise in low frequency band below 1 kHz. In this paper, we propose a modeling method to estimate the underwater shipping noise using the voyage information of ship observed in AIS (Automatic Identification System). For the purpose of ship noise modeling, the navigation information of the vessels operating in the southern part of Jeju was observed using AIS and underwater noise was measured by installing a hydrophone in the experimental area to verify the modeled ship noise. AIS data were used to model the noise level of ship and compared with measured underwater noise. The variation of noise level with time was found to be similar, and the cause of the error was discussed. Through this study, it was confirmed that the noise level of ship can be estimated within 5 dB error range using AIS data.

• Journal of Digital Convergence
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• v.18 no.10
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• pp.397-402
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• 2020

Hologram can be categorized into analog and digital hologram but there's a clear limitation in expensive equipment and content realization for ordinary people to realize. In addition, it's required to conduct study on hologram contents with interaction added, escaping out of exiting stable format like endlessly repetitive contents or passive view through specific video. Therefore, this article aims to suggest fusion image system, especially focusing on floating hologram among similar holograms. Eight elements of hologram interaction are as follows: height of camera in a three-dimensional space, interval between 3D model, overlapped model, scale, animation, position, color and 3D model change. For the floating hologram, the audience can control by themselves in real time, the popular, active hologram contents-making methodology is suggested by making the best use of fusion image system and making floating hologram easily without using expensive hologram equipment. The image system developed in actual exhibition and feedback should be complemented to develop better hologram image system.

• The Journal of the Acoustical Society of Korea
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• v.39 no.4
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• pp.279-285
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• 2020

The study on the temporal and spatial monitoring of passing vessels is important in terms of protection and management the marine ecosystem in the coastal area. In this paper, we propose the automatic detection technique of passing vessel by utilizing an artificial intelligence technology and broadband striation patterns which are characteristic of broadband noise radiated by passing vessel. Acoustic measurements to collect underwater noise spectrum images and ship navigation information were conducted in the southern region of Jeju Island in South Korea for 12 days (2016.07.15-07.26). And the convolution neural network model is optimized through learning and validation processes based on the collected images. The automatic detection performance of passing vessel is evaluated by precision (0.936), recall (0.830), average precision (0.824), and accuracy (0.949). In conclusion, the possibility of the automatic detection technique of passing vessel is confirmed by using an artificial intelligence technology, and a future study is proposed from the results of this study.

• Mycobiology
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• v.48 no.4
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• pp.326-329
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• 2020

Valuable natural compounds produced by a variety of microorganisms can be used as lead molecules for development of new agrochemicals. Furthermore, high-throughput in vitro screening systems with specific modes of action can increase the probability of discovery of new fungicides. In the current study, a rapid assay tested with various microbes was developed to determine the degree of respiratory inhibition of Saccharomyces cerevisiae in two different liquid media, YG (containing a fermentable carbon source) and NFYG (containing a non-fermentable carbon source). Based on this system, we screened 100 fungal isolates that were classified into basidiomycetes, to find microbial secondary metabolites that act as respiratory inhibitors. Consequently, of the 100 fungal species tested, the culture broth of an IUM04881 isolate inhibited growth of S. cerevisiae in NFYG medium, but not in YG medium. The result is comparable to that from treatment with kresoxim-methyl used as a control, suggesting that the culture broth of IUM04881 isolate might contain active compounds showing the inhibition activity for respiratory chain. Based on the assay developed in this study and spectroscopic analysis, we isolated and identified an antifungal compound (-)-oudemansin A from culture broth of IUM04881 that is identified as Oudemansiella venosolamellata. This is the first report that (-)-oudemansin A is identified from O. venosolamellata in Korea. Taken together, the development of this assay will accelerate efforts to find and identify natural respiratory inhibitors from various microbes.

• Molecules and Cells
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• v.41 no.8
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• pp.799-807
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• 2018

Emerging evidence has suggested that cellular crosstalk between RNF168 and poly(ADP-ribose) polymerase 1 (PARP1) contributes to the precise control of the DNA damage response (DDR). However, the direct and reciprocal functional link between them remains unclear. In this report, we identified that RNF168 ubiquitinates PARP1 via direct interaction and accelerates PARP1 degradation in the presence of poly (ADP-ribose) (PAR) chains, metabolites of activated PARP1. Through mass spectrometric analysis, we revealed that RNF168 ubiquitinated multiple lysine residues on PARP1 via K48-linked ubiquitin chain formation. Consistent with this, micro-irradiation-induced PARP1 accumulation at damaged chromatin was significantly increased by knockdown of endogenous RNF168. In addition, it was confirmed that abnormal changes of HR and HNEJ due to knockdown of RNF168 were restored by overexpression of WT RNF168 but not by reintroduction of mutants lacking E3 ligase activity or PAR binding ability. The comet assay also revealed that both PAR-binding and ubiquitin-conjugation activities are indispensable for the RNF168-mediated DNA repair process. Taken together, our results suggest that RNF168 acts as a counterpart of PARP1 in DDR and regulates the HR/NHEJ repair processes through the ubiquitination of PARP1.

• Biomolecules & Therapeutics
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• v.28 no.1
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• pp.74-82
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• 2020

Alzheimer's disease (AD) is a progressive and most frequently diagnosed neurodegenerative disorder. However, there is still no drug preventing the progress of this disorder. β-Amyrin, an ingredient of the surface wax of tomato fruit and dandelion coffee, is previously reported to ameliorate memory impairment induced by cholinergic dysfunction. Therefore, we tested whether β-amyrin can prevent AD-like pathology. β-Amyrin blocked amyloid β (Aβ)-induced long-term potentiation (LTP) impairment in the hippocampal slices. Moreover, β-amyrin improved Aβ-induced suppression of phosphatidylinositol-3-kinase (PI3K)/Akt signaling. LY294002, a PI3K inhibitor, blocked the effect of β-amyrin on Aβ-induced LTP impairment. In in vivo experiments, we observed that β-amyrin ameliorated object recognition memory deficit in Aβ-injected AD mice model. Moreover, neurogenesis impairments induced by Aβ was improved by β-amyrin treatment. Taken together, β-amyrin might be a good candidate of treatment or supplement for AD patients.

• Journal of Radiation Industry
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• v.6 no.1
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• pp.23-29
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• 2012

In this study, we investigated the genetic variation in the general of monocot model plant (rice) in response to various ionizing irradiations including gamma-ray, ion beam and cosmic-ray. The non-irradiated and three irradiated (200 Gy of gamma-ray and 40 Gy of ion beam and cosmic-ray) plants were analyzed by AFLP technique using capillary electrophoresis with ABI3130xl genetic analyzer. The 29 primer combinations tested produced polymorphism results showing a total of 2,238 bands with fragments sizes ranged from 30 bp to 600 bp. The number of polymorphism generated by each primer combinations was varied significantly, ranging from 2 (M-CAC/E-ACG) to 158 (M-CAT/E-AGG) with an average of 77 bands. Polymorphic peaks were detected as 1,269 with an average of 44 per primer combinations. By UPGMA (Unweighted Pair Group Method using Arithmetic clustering) analysis method, the clusters were divided into non-irradiated sample and three irradiated samples at a similarity coefficient of 0.41 and three irradiation samples was subdivided into cosmic-ray and two irradiation samples (200 Gy of gamma-ray and 40 Gy of ion beam) at similarity coefficient of 0.48. Similarity coefficient values ranged from 0.41 to 0.55.

• Journal of Radiation Industry
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• v.5 no.1
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• pp.47-54
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• 2011

In this study, we investigated to evaluate differential expression of genes encoding lipid transfer proteins (LTP) by acute and chronic gamma irradiation in rice. After acute and chronic gamma irradiation by 100 Gy and 400 Gy to rice plant, necrotic lesion was observed in the leaf blade and anthocyanin contents were increased. We isolated a total of 21 rice lipid transfer protein (LTP) genes in the TIGR database, and these genes were divided into four different groups on the basis of nucleotide sequences. The LTP genes also were classified as different four classes according to expression pattern using RT-PCR. Group A, B contained genes with increased expression and decreased expression in acute and chronic, respectively. Group C contained genes with contrasted expression pattern. Group D wasn't a regular pattern. But the specific affinity was not obtained between two grouping.