• Journal of Gastric Cancer
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• 제15권2호
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• pp.77-86
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• 2015

Laparoscopic proximal gastrectomy (LPG) is theoretically a superior choice of minimally-invasive surgery and function-preserving surgery for the treatment of proximal early gastric cancer (EGC) over procedures such as laparoscopic total gastrectomy (LTG), open total gastrectomy (OTG) and open proximal gastrectomy (OPG). However, LPG and OPG are not popular surgical options due to three main concerns: the first, oncological safety; the second, functional benefits; and the third, anastomosis-related late complications (reflux symptoms and anastomotic stricture). Numerous recent studies have concluded that OPG and LPG present similar oncological safety profiles and improved functional benefits when compared with OTG and LTG. While OPG with modified esophagogastrostomy does not provide satisfactory results, OPG with modified esophagojejunostomy showed similar rates of anastomosis-related late complications when compared to OTG. At this stage, no standard reconstruction method post-LPG exists in the clinical setting. We recently showed that LPG with double tract reconstruction (DTR) is a superior choice over LTG for proximal EGC in terms of maintaining body weight and preventing anemia. However, as there is no definitive evidence in favor of LPG with DTR, a randomized clinical trial comparing LPG with DTR to LTG was recommended. This trial, the Korean Laparoscopic Gastrointestinal Surgery Study-05 (NCT01433861), is expected to assist surgeons in choice of surgical approach and strategy for patients with proximal EGC.

• The Korean Journal of Pain
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• 제22권2호
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• pp.167-170
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• 2009

Pharmacological management is the first choice for treatment of the trigeminal neuralgia patients; however, if this mode of treatment fails a minimally invasive procedure should be performed. One of the most commonly used procedures is conventional radiofrequency lesioning of the Gasserian ganglion. Despite its popularity and success rate, this technique has disadvantages such as diminished corneal reflex, masseter weakness, numbness and anesthesia dolorosa. As a result, many studies have been conducted in an attempt to find a better method of treating trigeminal neuralgia. We report here a case of a trigeminal neuralgia patient that was treated with pulsed radiofrequency lesioning of the supraorbital and supratrochlear nerve due to pain in the frontal head that was refractory to the pharmacological treatments. Following the procedure, the Visual Analogue Scale score for pain decreased to 1-2/10 and the pain relief persisted for 7 months. These results indicate that pulsed radiofrequency treatment of the peripheral nerve may be useful for trigeminal neuralgia patients that do not respond to pharmacological treatments.

• Archives of Plastic Surgery
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• 제47권1호
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• pp.62-69
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• 2020

Background Cryolipolysis, a preferred method for minimally invasive body contouring, involves the noninvasive cooling of adipocytes to induce lipolysis without damaging other tissues. This study aimed to evaluate the safety and efficacy of cryolipolysis for the treatment of excessive fat tissue. Methods Between May 2014 and December 2017, 231 patients with 448 areas of interest were enrolled and their records were retrospectively reviewed. We used five different vacuum applicators, and the best-fitting applicator was used for each area. One cycle of cryolipolysis was applied at a cooling intensity factor of 41.6. The efficacy was evaluated 12 weeks after treatment via review of clinical photographs, the pinch test, and ultrasonographic measurements of fat thickness. The occurrence of any complications was also assessed. Results The volume was reduced in all of the areas to which cryolipolysis was applied. The rate of reduction of the fat layer as measured via the pinch test was 19.2%, and the rate of the decrease in fat layer thickness as measured via ultrasonography was 22.8%. Fat reduction of the upper arm differed significantly from that of the abdomen and flank, but no significant difference was found between sexes. The side effects were limited to erythema, edema, bruising, and numbness at the treatment site and resolved without treatment. Conclusions Cryolipolysis, with new and better-fitting applicators, is safe, fast, and effective for the reduction of excessive fat tissue on the abdomen, back, flank, and extremities. It is a good option for treating excess adipose tissue in Asian patients.

• Journal of Chest Surgery
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• 제32권9호
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• pp.835-839
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• 1999

1974년에 말기 신부전증 환자에서 심폐바이패스를 이용한 관상동맥우회술이 처음 보고된 이래 고위 穩\ulcorner인 만성 신부전증 환자들에서의 관상동맥우회술에 대한 많은 연구 논문들이 발표되어 왔다. 만성 신부전증 환자들은 고혈압, 당뇨 등을 동반하는 경우가 종종 있으며, 이 질환들의 합병증 혹은 만성 신부전증 자체가 관상동맥우회술의 단기및 장기 생존율에 영향을 미칠수 있다. 개심술을 받은 말기 신부전증 환자들에서는 감염과 패혈증 등의 합병증의 발생률이 높으며, 수술전후의 수액량과 전해질 장애 등으로 수술 위험도가 증 가하는 것으로 알려져 왔다. 저자들은 3예의 만성 신부전증 환자들에서 심폐바이패스를 사용하지 않고 관상 동맥우회술을 시행하여 그 결과를 발표하고자 한다.

• Journal of Korean Neurosurgical Society
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• 제29권3호
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• pp.372-378
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• 2000

The carpal tunnel syndrome is one of the most common entrapment neuropathy. Surgical treatments consist of conventional open technique, alternative technique using retinaculatome, and endoscopic surgery. This study compares the outcomes of surgical treatment of carpal tunnel syndrome following conventional versus endoscopic release. The authors reviewed 56 cases of 33 patients with carpal tunnel syndrome treated surgically in our institute from January 1991 to May 1998. The follow-up evaluation was possible in 36 cases of 20 patients who had conventional release and in 11 cases of 7 patients with endoscopic release. The following parameters were evaluated for comparison : improvement of symptom, return to normal work, recovery of strength of grip and pinch, rate of complication, follow-up electrophysiologic finding. Compared with open decompression, the group of endoscopic decompression needed significantly less time to go back to work(p<0.001). Also strength of grip and pinch improved faster in the group of endoscopic decompression as well, compared with open decompression(p<0.05). These results indicate that endoscopic procedure is an excellent, minimally invasive method to treat carpal tunnel syndrome, performed by surgeons who are fully aware of the anatomy.

• Archives of Plastic Surgery
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• 제48권3호
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• pp.323-328
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• 2021

Background Lymphaticovenular anastomosis (LVA) is a minimally invasive surgical procedure used to treat lymphedema. Volumetric measurements and quality-of-life assessments are often performed to assess the effectiveness of LVA, but there is no method that provides information regarding postoperative morphological changes in lymphatic vessels and veins after LVA. Photoacoustic lymphangiography (PAL) is an optical imaging technique that visualizes the distribution of light-absorbing molecules, such as hemoglobin or indocyanine green (ICG), and provides three-dimensional images of superficial lymphatic vessels and the venous system simultaneously. In this study, we performed PAL in lymphedema patients before and after LVA and compared the images to evaluate the effect of LVA. Methods PAL was performed using the PAI-05 system in three patients (one man, two women) with lymphedema, including one primary case and two secondary cases, before LVA. ICG fluorescence lymphography was performed in all cases before PAL. Follow-up PAL was performed between 5 days and 5 months after LVA. Results PAL enabled the simultaneous visualization of clear lymphatic vessels that could not be accurately seen with ICG fluorescence lymphography and veins. We were also able to observe and analyze morphological changes such as the width and the number of lymphatic vessels and veins during the follow-up PAL after LVA. Conclusions By comparing preoperative and postoperative PAL images, it was possible to analyze the morphological changes in lymphatic vessels and veins that occurred after LVA. Our study suggests that PAL would be useful when assessing the effect of LVA surgery.

• Journal of Gastric Cancer
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• 제22권3호
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• pp.235-247
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• 2022

Purpose: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between patients with esophagogastric junction cancer (EGJC) and those with upper third gastric cancer (UGC) undergoing the same gastrectomy procedure to evaluate the impact of tumor location on postoperative QOL. Methods: The Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire was distributed in 70 institutions to 2,364 patients who underwent gastrectomy for EGJC or UGC. A total of 1,909 patients were eligible for the study, and 1,744 patients who underwent total gastrectomy (TG) or proximal gastrectomy (PG) were selected for the final analysis. These patients were divided into EGJC and UGC groups; thereafter, the PGSAS-45 main outcome measures (MOMs) were compared between the two groups for each type of gastrectomy. Results: Among the post-TG patients, only one MOM was significantly better in the UGC group than in the EGJC group. Conversely, among the post-PG patients, postoperative QOL was significantly better in 6 out of 19 MOMs in the UGC group than in the EGJC group. Conclusions: Tumor location had a minimal effect on the postoperative QOL of post-TG patients, whereas among post-PG patients, there were definite differences in postoperative QOL between the two groups. It seems reasonable to conservatively estimate the benefits of PG in patients with EGJC compared to those in patients with UGC.

• Nuclear Engineering and Technology
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• 제53권7호
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• pp.2334-2340
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• 2021

Radioactive particle tracking (RPT) is a minimally invasive nuclear technique that tracks a radioactive particle inside a volume of interest by means of a mathematical location algorithm. During the past decades, many algorithms have been developed including ones based on artificial intelligence techniques. In this study, RPT technique is applied in a simulated test section that employs a simplified mixer filled with concrete, six scintillator detectors and a¹³⁷Cs radioactive particle emitting gamma rays of 662 keV. The test section was developed using MCNPX code, which is a mathematical code based on Monte Carlo simulation, and 3516 different radioactive particle positions (x,y,z) were simulated. Novelty of this paper is the use of a location algorithm based on a deep learning model, more specifically a 6-layers deep rectifier neural network (DRNN), in which hyperparameters were defined using a Bayesian optimization method. DRNN is a type of deep feedforward neural network that substitutes the usual sigmoid based activation functions, traditionally used in vanilla Multilayer Perceptron Networks, for rectified activation functions. Results show the great accuracy of the DRNN in a RPT tracking system. Root mean squared error for x, y and coordinates of the radioactive particle is, respectively, 0.03064, 0.02523 and 0.07653.

• 한국간담췌외과학회지
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• 제27권4호
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• pp.372-379
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• 2023

Backgrounds/Aims: While single-incision laparoscopic cholecystectomy (SILC) has advantages in cosmesis and postoperative pain, its utilization has been limited. This study raises the possibility of expanding its indication to acute cholecystitis with the novel method of solo surgery under retrospective analysis. Methods: We compared the outcomes of SILC (n = 58) to those of three-incision laparoscopic cholecystectomy (TILC; n = 117) for acute cholecystitis, being performed from March 2014 to December 2015. Results: Intraoperative results, including the operation time, did not differ significantly, except for drain catheter insertion (p = 0.004). Each group had 1 case of open conversion due to common bile duct injury. There was no significant difference in the length of hospital stay. Either group by itself was not a risk factor for complications, but in preoperative drainage for intraoperative perforation, 3 factors of intraoperative perforation, biliary complication, and history of upper abdominal operation for additional port, only American Society of Anesthesiology (ASA) scores for postoperative complication of Clavien-Dindo grades III and IV were significant risk factors. Conclusions: Our study findings showed comparative outcomes between both groups, providing evidence for the safety and feasibility of SILC for acute cholecystitis.

• Journal of Chest Surgery
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• 제36권3호
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• pp.164-174
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• 2003

배경: 너스 수술은 최근에 개발된 금속막대를 이용한 누두흉의 최소 침습 수술법이다. 수술 수기가 간단하고 작은 흉터로 교정 모양이 양호하여 호평을 받고 있다. 그러나 지금까지 복합형태의 누두흉은 교정이 어려워 표준형 소아 환자들에게만 적용되어 왔다. 저자들은 새로 개발된 비대칭형이나 성인의 누두흉의 교정을 위한 변형 기법들을 이용하여 얻은 수술 결과를 보고하고자 한다. 대상 및 방법: 1999년 8월부터 2002년 6월까지 본원에서 너스 수술법 및 변형 기법으로 수술한 322명을 대상으로 하였다. 그 중 71명(22%)은 성인이었다. 정밀한 교정을 위하여 누두흉의 형태를 분류하였다. 대칭형과 비대칭형으로 나누고 비대칭형은 편심형과 불균형형으로 세분하였다. 수술 시에 대칭형으로 교정하기 위하여 막대를 여러 가지 모양으로 구부려 사용하였다. 결과: 형태분류 상 대칭형은 57.5%(185/322)였고 비대칭형은 42.5% (137/322)였다. 비대칭형의 아형으로서 편심형, 불균형형 및 복합형은 각각 71, 47, 19명이었나. 수술의 주변형 기법은 막대의 형태와 고정법에 관한 것이었다. 비대칭형 누두흉 125명(38.8%)에게 여러 모양의 비대칭형 막대가 적용되었다. 성인 환자 51명(15.8%)에게 이중 막대 기법이나 복합형 막대 기법이 적용되었다. 막대의 편위를 방지하기 위한 고정법으로서 철사를 이용한 늑골의 다지점 고정법을 사용하였다. 수술 후 주요 합병증은 기흉이 24명(7.5%), 막대 편위가 11명(3.4%)이었다. 너스 수술 후 2년이 경과한 42명이 막대 제거 수술을 받았다. 걸론: 너스 수술법은 안전하고 효과적이었다. 누두흉의 형태를 정밀하게 분류하고 이에 따른 적확한 변형 기법을 적용함으로써 비대칭형과 성인 누두흉 등, 모든 형태의 누두흉을 교정할 수 있었다.