• 제목/요약/키워드: Miniature

검색결과 814건 처리시간 0.028초

형광과 여기광을 공간적으로 분리하는 바이오칩용 소형 형광측정시스템 (Miniature Biochip Fluorescence Detection System with Spatial Separation of Fluorescence from Excitation Light)

  • 김호성;김용권;박주한;이국녕;최재호
    • 대한전기학회논문지:전기물성ㆍ응용부문C
    • /
    • 제54권8호
    • /
    • pp.378-383
    • /
    • 2005
  • We report the development of miniature fluorescence detection systems that employ miniature prism, mirrors and low coat CCD camera to detect the fluorescence emitted from 40 fluorescently-labeled protein patterns without scanner. This kind of miniature fluorescence detection system can be used in point of care. We introduce two systems, one uses prism+mirror block and the other uses prism and two mirrors. A large NA microscope eyepiece and low cost CCD camera are used. We fabricated protein chip containing multi-pattern BSA labeled with Cy5, using MEMS technology and modified the surface chemically to clean and to immobilize proteins. The measurements show that the combination of prism and mirrors can homogenize elliptical excitation light over the sample with higher optical efficiency, and increase the separation between excitation and fluorescence light at the CCD to give higher signal intensity and higher signal to noise ratio. The measurements also show that protein concentrations ranging from 10 ng/ml to 1000 ng/ml can be assayed with very small error. We believe that the proposed fluorescence detection system can be refined to build a commercially valuable hand-held or miniature detection device.

애완 미니 돼지의 Malassezia furfur에 의한 외이도염 증례 (Otitis Externa caused by Malassezia furfur in a Miniature Pig)

  • 한재익;나기정
    • 한국임상수의학회지
    • /
    • 제26권3호
    • /
    • pp.303-305
    • /
    • 2009
  • A 7-month-old, female miniature pig was presented with excessive cerumen and pruritus. Greasy brown cerumen in both exteranal ear canal and sporadic head shaking were observed in the physical examination. Numerous budding yeasts in the cerumen were examined on microscopic examination. For species identification, PCR-RFLP using incubated colony on modified Dixon's medium was performed and finally, causative yeast was identified as M. furfur.

초고속 소형 BLDC의 순시전압 제어에 의한 토크 리플 억제 (Torque ripple Reduction of High speed Minituale BLDC using instantaneous voltage control)

  • 이동희;김태형;안진우;원태현
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2006년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
    • /
    • pp.91-94
    • /
    • 2006
  • Miniature BLDC is widely used in industrial applications and especially medical appliances because of there character that high driving efficiency and high torque characteristic. However torque ripple of a high speed miniature BLDC is serous in switching period cue to the very electrical time constant. This paper present instant voltage and current control for torque ripple reduction of a high speed miniature BLDC. Computer simulation and experiment test for 40,000 rpm miniature BLDC show the verification of the proposed control method.

  • PDF

Development of a Miniature Air-bearing Stage with a Moving-magnet Linear Motor

  • Ro, Seung-Kook;Park, Jong-Kweon
    • International Journal of Precision Engineering and Manufacturing
    • /
    • 제9권1호
    • /
    • pp.19-24
    • /
    • 2008
  • We propose a new miniature air-bearing stage with a moving-magnet slotless linear motor. This stage was developed to achieve the precise positioning required for submicron-level machining and miniaturization by introducing air bearings and a linear motor sufficient for mesoscale precision machine tools. The linear motor contained two permanent magnets and was designed to generate a preload force for the vertical air bearings and a thrust force for the stage movement. The characteristics of the air bearings, which used porous pads, were analyzed with numerical methods, and a magnetic circuit model was derived for the linear motor to calculate the required preload and thrust forces. A prototype of a single-axis miniature stage with dimensions of $120\;(W)\;{\times}\;120\;(L)\;{\times}\;50\;(H)\;mm$ was designed and fabricated, and its performance was examined, including its vertical stiffness, load capacity, thrust force, and positioning resolution.

초소형 무연 단일 솔더볼 연결부의 전단강도 평가 (Evaluation of Shear Strength of a Miniature Lead-free Single Solder Ball Joint)

  • 주세민;김호경
    • 한국안전학회지
    • /
    • 제25권6호
    • /
    • pp.14-21
    • /
    • 2010
  • A miniature single solder ball joint is designed to mimic the actual solder joints used in the micro-electric industries. Shear tests were conducted to evaluate the mechanical behavior of miniature single solder joints at intermediate strain rates from $0.019\;s^{-1}$ to $2.16\;s^{-1}$ at room temperature. The shear fracture strength of the present solder ball joints generally increased with increasing shear strain rate, ranging from 32 to 51MPa. This behavior is affected by the sensitivity of bulk solder strength to strain rate. Shear fracture mode changed from brittle to partial ductile (failure inside the bulk solder) with an increase of shear speed. The unloading shear fracture toughness is generally consistent with the measure of the amount of bulk solder on the fractured surface.

다이아프램 감지부 구조를 갖는 소형 로드셀의 정격출력 계산에 관한 연구 (Calculation of rated output in diaphragm type miniature load cell)

  • 권영하;강대임;주진원
    • 한국정밀공학회지
    • /
    • 제7권2호
    • /
    • pp.58-64
    • /
    • 1990
  • As the miniature load cells have small inner space and sensing elements of which are thin and very sensitive to manufacturing conditions, it is very difficult to predict the rated outputs and control them by using the compensation resistor. The very useful equation has been derived for calculation of theoretical rated outputs for diaphragm type miniature load cells when commercial diaphragm strain gages are used. Four diaphragm type miniature load cells of which capacities are from 300 N to 1, 000 N and outer diameters are 20 mm and 26.5 mm are manufactured. The differences between calculating results and actural ones are less than 5%. According to numerical analysis the decrease of rated outputs caused to main error is examined in existence of loading button.

  • PDF

NTC 써미스터가 내장된 항온 제어용 소형 열전 냉각 모듈 제조 (Fabrication of NTC thermistor embedded Miniature Thermoelectric Cooling Module for Temperature Control)

  • 박종원;최정철;황창원;최승철
    • 마이크로전자및패키징학회지
    • /
    • 제11권3호
    • /
    • pp.83-89
    • /
    • 2004
  • NTC 써미스터를 내장시킨 소형의 열전 냉각 모듈을 제작하고 LD와 같은 광통신부품에 적용하기 위한 온도제어 및 항온유지 특성을 분석하였다 BiTe계 열전반도체 21쌍으로 구성된 열전 모듈은 크기 $7.2 mm{\times}9 mm{\times}2.2 mm$이고, 내장된 써미스터의 빠른 응답속도로 인해 정밀온도제어가 가능하다. 열전 모듈은 성능 지수(Z) $2.5{\times}10^{-3}$/K, 300 K에서 최대 온도차(${\Delta}T_{max}$) 72 K, 최대 흡열량($Q_{max}$) 2.2W 값을 나타내었으며 온도 제어 정밀도는 대기 중에서 ${\pm}0.1^{\circ}C$내였다. 이는 광통신 부품의 작동 환경 안정성을 확보할 수 있는 항온제어용 소형 열전 모듈로서 적용이 가능하다.

  • PDF

소형콘과 T-bar 관입기를 이용한 카올린 점토의 비배수전단강도 산정에 관한 연구 (Determination of Undrained Shear Strength using Miniature Cone and T-bar Penetrometers for Kaolin Clay)

  • ;추연욱
    • 대한토목학회논문집
    • /
    • 제38권3호
    • /
    • pp.429-438
    • /
    • 2018
  • 원추형콘과 T-bar 관입시험기는 점토의 비배수전단강도를 측정하기 위해 널리 사용된다. 축소모형시험의 경우 소형관입시험기가 사용되어야 하지만 경험상관계수에 대해 발표된 자료가 부족하다. 본 연구에서는 소형콘과 소형T-bar 관입시험기의 경험상관계수를 도출하기 위한 시험시스템을 구축하였고, 카올린점토에 대하여 실험을 수행하였다. 직경 350mm의 강재원형챔버를 사용하여 4개의 모형지반을 조성하였고, 각 모형지반은 다른 선행압밀응력에서 압밀하여 비배수전단강도를 조절하였다. 경계면 효과, 관입속도, 직경 및 형상의 영향을 확인하기 위하여 다른 직경을 가진 두 직경의 소형콘(10mm, 16mm)과 직경 10mm T-bar를 이용하여 시험을 수행하였다. 또한 관입시험 후의 시편을 채취하여 비압밀비배수삼축시험을 수행하여 비배수전단강도로 결정하였다. 최종적으로 비배수전단강도와 관입시 선단저항력의 상관관계를 통해 경험상관계수를 산정하였다.

미니돼지정액의 보존 시 콜레스테롤과 혈청 알부민이 정자 성상과 지질 과산화에 미치는 영향 (Effect of Cholesterol and Serum Albumin on Sperm Ability and Lipid Peroxidation during the Storage of Miniature Pig Sperm)

  • 김동우;이용승;유한준;정희태;양부근;박춘근
    • 한국수정란이식학회지
    • /
    • 제26권1호
    • /
    • pp.71-78
    • /
    • 2011
  • This study was undertaken to find out the effect of cholesterol and serum albumin on sperm ability and lipid peroxidation levels period to the liquid storage of miniature pig sperm. Ejaculated semen from miniature pigs was collected by gloved-hand method into a pre-warmed ($37^{\circ}C$) thermos bottle, and extended with Modena solution {with and without BSA, methyl-beta-cyclodextrin (-cholesterol) and cholesterol loaded cyclodextrin (+cholesterol)}. Each semen was assessed for viability (SYBR-14/PI staining) and acrosome intactness, intensity and capacitation status by chlorotetracycline (CTC) staining at 1, 3, 5, 7 and 10 days of storage. At for the effects of cholesterol and serum albumin on lipid peroxidation, semen were incubated with $H_2O_2$ ($10\;{\mu}M$), and lipid peroxidation level were measured by flow cytometry using the lipid peroxidation reporter probe $C_{11}-BODIPY^{581/591}$. The result, lipid peroxidation level in sperm added with cholesterol were lower in $10\;{\mu}M$ $H_2O_2$ compared to the added sperm with serum albumin. Also, added cholesterol to sperm had significant (p<0.05) higher viability when storage for 7 and 10 days and lower when 10 days of storage percentage of acrosome-reacted sperm (AR pattern) in acrosome state as say result compared to other treated groups. In conclusion, role of cholesterol during lipid storage in miniature pig spermatozoa was protected boar spermatozoa from lipid peroxidation prior to lipid storage. Addition serum albumin during lipid storage in sperm may be induce sperm membrane damage by lipid peroxidation. Therefore, addition of cholesterol to miniature pig sperm will be lead to extension of liquid storage periods.