• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.317-321
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• 2016

Detection of micrometastasis in sentinel lymph nodes (SLNs) is a very useful tool for appropriate assessment of the clinical stage of disease in breast cancer patients. Early identification of clinically relevant disease could lead to early treatment or staging approaches for breast cancer patient. Micrometastases in SLNs of women with invasive breast cancer are of great significance in this context. In this study we examined SLN biopsies considered to have small numbers of cancerous cells by real time RT-PCR. All of the samples underwent immunohistochemical staining for cytokeratin for confirmation of the presence or absence of micrometastases. BUB1b expression assay of selected patients with and without metastasis showed overexpression in the former, but not in normal breast and lymph node tissue. Our results may be taken into account in the discussion about the merits of routine use of molecular assessment in pathogenetic studies of SLNs.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.179-183
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• 2016

Breast cancer is the most prevalent type of cancer among women around the world, and mortality is primarily caused by micro-metastatic disease. The complex mechanisms of breast cancer invasion and metastasis are intrinsically related to the malignant cell type so that early detection of micro-metastases can help prolongation of survival for patient. The aim of the present research work was evaluation of the expression status of mammoglobin protein as a candidate molecular marker in the negative sentinel lymph node (SLN). Fifty tumor specimens, and 50 normal adjacent breast tissue samples from the same patients were selected on the basis of having more than 10% tumor content for RNA extraction from SLNs. Tumor samples and normal adjacent breast tissue were archived in the form of frozen fresh tissue in liquid nitrogen. Real-time PCR was performed on a Bioner life express gradient thermal cycler system. Mammoglobin gene overexpression in breast cancer metastasis was investigated. Single marker results were mammaglobin 66.7% and CK19 50.0%, with 58.3% for the two in combination. Due to improved outcome with at least 3 genes (83.3%), it seems, triple marker evaluation will be most likely useful for detecting micro-metastases instead of studying separate genes.

• Journal of electromagnetic engineering and science
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• 제4권3호
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• pp.128-136
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• 2004

In this paper,. with the aim of achieving the expected performance improvement for a polarization diversity system, we analyzed two-branch polarization diversity at the receiving end of a mobile link which a transmitter emits circularly polarized wave. In this analysis, to calculate the correlation coefficient considered by XPD(cross polarization discrimination) between the two received signals, a simple theoretical model of circular polarization diversity is adopted. From the analysis results, it is clearly seen that the correlation coefficient of circular polarization diversity evaluated by the XPD is less than that of conventional linear polarization diversity. And also, we designed and implemented a circular polarization diversity system with micro-strip antenna. By using the circular polarization diversity system, we analyzed the measured data in indoor NLOS(Non-Line-Of-Sight) environments. From this analysis results, it is also clearly seen that the diversity effect of circular polarization diversity system shows better performance compared to the conventional linear diversity system by about 3 dB high.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.2070-2075
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• 2004

Performance of a solid oxide fuel cell (SOFC) can be enhanced by converting thermal energy of its high temperature exhaust gas to mechanical power using a micro gas turbine (MGT). A MGT plays also an important role to pressurize and warm up inlet gas streams of the SOFC. In this study, the influence of performance characteristics of the tubular SOFC on the hybrid power system is discussed. For this purpose, detailed heat and mass transfer with reforming and electrochemical reactions in the SOFC are mathematically modeled, and their results are reflected to the performance analysis. The analysis target is 220kWe SOFC/MGT hybrid system based on the tubular SOFC developed by Siemens-Westinghouse. Special attention is paid to the ohmic losses in the tubular SOFC counting not only current flow in radial direction, but also current flow in circumferential direction through the anode and cathode.

• Advances in concrete construction
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• 제10권3호
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• pp.195-209
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• 2020

This study investigates the behavior of ultra-high-performance fiber-reinforced concrete (UHPFRC) with hybrid macro-micro steel and macro steel-polypropylene (PP) fibers. Compression, direct and indirect tension tests were carried out on cubic and cylindrical, dogbone and prismatic specimens, respectively. Three types of macro steel fibers, i.e., round crimped (RC), crimped (C), and hooked (H) were combined with micro steel (MS) and PP fibers in overall ratios of 2% by volume. Additionally, numerical analyses were performed to validate the test results. Parameters studied included, fracture energy, tensile strength, compressive strength, flexural strength, and residual strength. Tests showed that replacing PP fibers with MS significantly improves all parameters particularly flexural strength (17.38 MPa compared to 37.71 MPa). Additionally, the adopted numerical approach successfully captured the flexural load-deflection response of experimental beams. Lastly, the proposed regression model for the flexural load-deflection curve compared very well with experimental results, as evidenced by its coefficient of correlation (R²) of over 0.90.

• Steel and Composite Structures
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• 제43권6호
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• pp.773-784
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• 2022

This paper aims to investigate the axial compressive behavior of reinforced concrete (RC) columns strengthened with self-compacting and micro-expanding (SM) concrete-filled steel tubes (SM-CFSTs). Nine specimens were tested in total under the local axial compression. The test parameters included steel tube thickness, filling concrete strength, filling concrete type and initial axial preloading. The test results demonstrated that the initial stiffness, ultimate bearing capacity and ductility of original RC columns were improved after being strengthened by SM-CFSTs. The ultimate bearing capacity of the SM-CFST strengthened RC columns was significantly enhanced with the increase of steel tube thickness. The initial stiffness and ultimate bearing capacity of the SM-CFST strengthened RC columns were slightly enhanced with the increase of filling concrete strength. However, the effect of filling concrete type and initial axial preloading of the SM-CFST strengthened RC columns were negligible. Three equations for predicting the ultimate bearing capacity of the SM-CFST strengthened RC columns were compared, and the modified equation based on Chinese code (GB 50936-2014) was more precise.

• Journal of Forest and Environmental Science
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• 제26권1호
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• pp.1-7
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• 2010

Species diversity is one of the most important specifications of biological societies. Diversity of organisms, measurement of variety and examination of those hypotheses that are about reasons of diversity are such as affairs that have been desired by the ecologists for a long time. In this research, diversity of plant species in forest region, numbers of 60 sample plots in 256.00 square meters have been considered in random - systematic inventory was considered. In each sample plot, four micro-plots in 2.25 square meters in order to study on herbal cover, were executed that totally 240 micro-plots were considered. At each plot six diversity indices in relation to physiographic factors (slope, geographical aspect and altitude from the sea level) were studied. The results indicate that species diversity is more in the northern direction and also species diversity in slops less than 30% has the most amounts. Factor of altitude from the sea level did not have meaningful relation with species diversity. Through study on correlation of the numbers of species in sample plots with indices and also process and role of indices in different processors of analysis, Simpson's reciprocal index was suggested as suitable index in this type of studies.

• 한국지구과학회지
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• 제40권3호
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• pp.272-282
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• 2019

지진 관련 정책 입안과 수행에 우선적으로 고려되어야 할 정보가 지진 발생현황이지만, 대도시와 인구밀집 지역의 경우 높은 생활잡음으로 인해 작은 규모의 지진 발생을 정확히 인지하지 못하는 경우가 많다. 본 연구에서는 2010년부터 2017년까지 부산지역에서 발생했지만, 규모가 작아 기상청 지진목록에 수록되지 않은 미소 지진 10회를 파형의 유사성을 이용하여 검출하였고, 기존에 발생사실을 알고 있던 지진을 포함하여 총 12회의 지진을 분석에 사용하였다. 새로이 보고되는 지진은 선형을 보이면서 발생하고 있지만, 주변의 단층과 직접적으로 연관하여 해석하기에는 자료가 충분치 않다. 규모가 작은 미소 지진이 꾸준히 발생한다는 것은 지하에 지진을 일으키는 단층이 존재함을 시사하고, 부산과 같은 인구밀집 지역에서 과거 피해를 유발한 역사지진과 비슷한 규모의 지진이 발생한다면 대형 피해로 발전될 가능성이 매우 크다. 최근 우리나라에서 발생한 피해 유발 지진이 지표파열을 동반하지 않고 발생하고 있음을 고려할 때 현재 발생하고 있는 미소 지진 현황을 파악하여 지표 단층조사와 함께 지하단층을 규명하는데 활용하여야 한다.

• Transactions on Electrical and Electronic Materials
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• 제13권5호
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• pp.252-255
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• 2012

In order to characterize insulation properties of epoxy/micro-silica/nano-silicate composite (EMNC), long-term and short-term AC treeing tests were carried out undr non-uniform electric field generated between needle-plate electrodes. In a long-term test, a 10 kV (60 Hz) electrical field was applied to the specimen positioned between the electrodes with a distance of 2.7 mm in an insulating oil bath at $30^{\circ}C$, and a typical branch type electrical tree was observed in the neat epoxy resin and breakdown took place at 1,042 min after applying the 10 kVelectrical field. Meanwhile, the spherical tree with the tree length of $237{\mu}m$ was seen in EMNC-65-0.3 at 52,380 min (36.4 day) and then the test was stopped because the tree propagation rate was too low. In the short-term test, an electrial field was applied to a 3.5 mm-thick specimen at an increasing voltage rate of 0.5 kV/s until breakdown in insulating oil bath at $30^{\circ}C$ and $130^{\circ}C$, and the data was estimated by Weibull statistical analysis. The electrical insulation breakdown strength for neat epoxy resin was 1,763 kV/mm at $30^{\circ}C$, while that for EMNC-65-0.3 was 2,604 kV/mm, which was a modified value of 47%. As was expected, the breakdown strength decreased at higher test temperatures.

• 한국지반공학회논문집
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• 제19권2호
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• pp.171-178
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• 2003

날개크랙과 이차크랙은 암석의 일축압축 및 이축압축 조건에서 관측되는 특정한 형태의 크랙이다. 본 연구에서는 석고로 제작된 실험체내에 발생하는 날개크랙과 이차크랙의 형태적 측면을 미시적 및 거시적 관점에서 관측하였다. 날개크랙의 진행방향을 따라 미소인장크랙이 관측되었으며 미소인장크랙은 공극간의 연결과 분지현상을 통하여 진전되었다. 날개크랙의 개시점에서 다중의 미소인장크랙의 개시가 관측되었으며 미소인장크랙은 굴곡진 진행을 보인다. 또한 이차크랙과는 달리 미소인장크랙은 상대적으로 일정한 크랙의 틈을 보이며 인장에 의한 할렬파괴에 의해 진행되는 것으로 나타났다. 이차크랙의 미시적 관측에서는 미소파쇄대가 관측되었다. 이차크랙의 파괴구간 내에서는 입자 및 집괴의 분리, 경사진 미소파쇄대의 형성 및 불규칙한 크기의 틈을 가진 미소파쇄대가 관측되었다. 이러한 결과는 이차크랙이 전단에 의해 형성됨을 보이고 있다 날개크랙과 이차크랙은 서로 다른 크기의 파괴진행구간을 보이고 있으며 각각의 크랙의 진행 방향에 직각방향으로 측정된 파괴진행구간의 폭은 날개크랙의 경우 10$\mu{m}$에서 20$\mu{m}$ 정도이며 이차크랙은 100$\mu{m}$에서 200$\mu{m}$ 정도이다.