• 자연, 터널 그리고 지하공간
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• 제21권1호
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• pp.101-112
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• 2019

This case study presented a simplified failure mechanism approach used as a preliminary deformation prediction for the Mexico City's metro system expansion. Because of the Mexico City's difficult subsoils, Line 12 project was considered one of the most challenging projects in Mexico. Mexico City's subsurface conditions can be described as a multilayered stratigraphy changing from soft high plastic clays to dense to very dense cemented sands. The Line 12 trajectory crossed all three main geotechnical Zones in Mexico City. Starting from to west of the City, Line 12 was projected to pass through very dense cemented sands corresponding to the Foothills zone changing to the Transition zone and finalizing in the Lake zone. Due to the change in the subsurface conditions, different constructions methods were implemented including the use of TBM (Tunnel Boring Machine), the NATM (New Austrian Tunneling Method), and cut-and-cover using braced Diaphragm walls for the underground section of the project. Preliminary crown and excavation front deformations were determined using a simplified failure mechanism prior to performing finite element modeling and analysis. Results showed corresponding deformations for the crown and the excavation front to be 3.5cm (1.4in) and 6cm (2.4in), respectively. Considering the complexity of Mexico City's difficult subsoil formation, construction method selection becomes a challenge to overcome. The use of a preliminary results in order to have a notion of possible deformations prior to advanced modeling and analysis could be beneficial and helpful to select possible construction procedures.

• 대한지리학회지
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• 제32권2호
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• pp.155-174
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• 1997

1994년 1월 1일 이후부터 공식적으로 발효한 NAFTA로 인하여 200l년 1월 1일까지는 멕시코ㆍ미국ㆍ캐나다 사이에 관세가 완전히 철폐될 예정이다. 패시코 북부지역의 변화는 이 지역의 도시성장에서 잘 나타나고 있다. 특히 국경지대에서 쌍둥이 도시화가 매우 급속히 진행되었다. 오늘날 멕시코 도시 순위 10위권 이내에 드는 세 도시(Ciudad Juarez, Tijuana, Mexicali)가 북부 국경지대에 위치한다. 멕시코 북부지역은 동서의 교류보다는 남북의 교류가 많았다. NAFTA로 인하여 멕시코 북부의 여러 하부지역들은 동서로 통합되는 것이 아니라 남북으로 통합되는 경향이 강화될 것으로 예측된다. 멕시코 북부 국경지대의 산업 발달은 멕시코인들에게는 고용기회를 확대시키고 미국인들에게는 저렴한 노동력을 이용할 수 있는 기회를 부여한다. NAFTA는 경제수준의 차가 큰 두 체제 사이의 경제통합이라는 점에서 향후 전세계적으로 전개될 지도 모르는 지역주의적 경제통합에 시사하는 바가 크다고 하겠다.

• Mycobiology
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• 제48권5호
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• pp.410-417
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• 2020

Fungal ecological interactions play a key role in structuring community assemblages. These associations may involve both antagonistic and synergistic relationships, which are commonly influenced by abiotic factors such as nutrient conditions. However, information for extreme, oligotrophic systems remain poor. Herein, interactions among key members of the aquatic transient fungal community (Aspergillus niger, Cladosporium sp., and Coprinellus micaceus) of a low-nutrient freshwater system in the Cuatro Ci enegas Basin, Mexico were studied. Pairwise interaction bioassays were explored in vitro under different nutrient conditions, including carbohydrates-rich, carbohydrates and amino peptides-rich, and low nutrients. Our results indicated that antagonistic patterns prevail among the studied taxa. However, nutrient-dependent changes were observed in Cladosporium sp. shifting to synergy under carbohydrates-rich conditions, suggesting changes in the fungal community composition as a result of nutrient enrichment. Remarkably, our findings contrast with previous work demonstrating mainly synergistic interactions between our tested fungal isolates and co-occurring autochthonous bacteria (Aeromonas spp. and Vibrio sp.) under low-nutrient conditions. This observation may indicate that bacteria and fungi exhibit distinct community-level responses, driven by nutrient conditions. This contributes to the knowledge of fungal community dynamics and interspecific interactions in an oligotrophic ecosystem, highlighting the relevance of nutrient-based shifts and antagonistic interactions in ecosystem dynamics.

• IMMUNE NETWORK
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• 제24권2호
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• pp.14.1-14.26
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• 2024

The inflammatory response during cutaneous leishmaniasis (CL) involves immune and non-immune cell cooperation to contain and eliminate Leishmania parasites. The orchestration of these responses is coordinated primarily by CD4⁺ T cells; however, the disease outcome depends on the Th cell predominant phenotype. Although Th1 and Th2 phenotypes are the most addressed as steers for the resolution or perpetuation of the disease, Th17 cell activities, especially IL-17 release, are recognized to be vital during CL development. Th17 cells perform vital functions during both acute and chronic phases of CL. Overall, Th17 cells induce the migration of phagocytes (neutrophils, macrophages) to the infection site and CD8⁺ T cells and NK cell activation. They also provoke granzyme and perforin secretion from CD8⁺ T cells, macrophage differentiation towards an M2 phenotype, and expansion of B and Treg cells. Likewise, immune cells from the inflammatory infiltrate have modulatory activities over Th17 cells involving their differentiation from naive CD4⁺ T cells and further expansion by generating a microenvironment rich in optimal cytokines such as IL-1β, TGF-β, IL-6, and IL-21. Th17 cell activities and synergies are crucial for the resistance of the infection during the early and acute stages; however, if unchecked, Th17 cells might lead to a chronic stage. This review discusses the synergies between Th17 cells and the inflammatory infiltrate and how these interactions might destine the course of CL.

• 한국재료학회:학술대회논문집
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• 한국재료학회 1992년도 추계학술발표강연 및 논문개요집
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• pp.13-13
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• 1992

• 한국재료학회:학술대회논문집
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• 한국재료학회 1992년도 추계학술발표강연 및 논문개요집
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• pp.15-15
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• 1992

• 한국수학사학회지
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• 제10권1호
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• pp.39-45
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• 1997

• Journal of Microbiology and Biotechnology
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• 제21권12호
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• pp.1345-1351
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• 2011

Vancomycin therapy failure due to the emergence of tolerance in pneumococci is increasing. The molecular mechanism of tolerance is not clear, but lytA and $pep^{27}$ are known to be involved. Our aim was to evaluate the expression of both genes in vancomycin-tolerant Streptococcus pneumoniae (VTSP) strains. Eleven VTSP strains from a total of 309 clinical isolates of S. pneumoniae from 1997 to 2006 were classified according to the criteria of Liu and Tomasz. All VTSP strains were evaluated for susceptibility according to CLSI criteria, serotype by the Quellung test, and clonality by PFGE. The expressions of lytA and $pep^{27}$ were analyzed in different growth phases by RT-PCR with and without vancomycin. Eighty-two percent of VTSP strains showed resistance to penicillin, and 100% were sensitive to vancomycin and cefotaxime. The most frequent serotypes of VTSP strains were 23F (4/11) and 6B (3/11). Clonal relationship was observed in only two strains. No significant changes were observed in $pep^{27}$ expression in the three phases of growth in VTSP strains with and without vancomycin. Interestingly, $pep^{27}$ expression in the stationary phase in the non-tolerant reference strain R6 was significantly higher. However, no significant differences in lytA expression were observed between VTSP and R6 strains during the phases of growth analyzed. The absence of changes in $pep^{27}$ expression in VTSP strains in the stationary phase may be related to their ability to tolerate high antibiotic concentrations, and thus, they survive and remain in the host under the antibiotic selective pressure reflected in therapeutic failure.

• 통상정보연구
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• 제11권3호
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• pp.363-390
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• 2009

This study investigates the role of private participation in FTA Negotiation in case of US, Mexico and Japan. We utilize Putnam(1988)'s two stage negotiation model, Schelling Conjecture and Principal-Agent(P-A) theory to understand the role of private sector in FTA Negotiation. Those theories are useful to understand the behavior and interaction of key players such as private sector, congress and government in FTA negotiation. Putnam(1988)'s two stage negotiation model divides the FTA negotiation process into two processes: the external negotiation with foreign country and domestic negotiation with domestic interest group. Principal-Agent(P-A) theory provides the theoretical foundation of Putnam's two stage negotiation model, which is that principal's interest is not identical to the interest of Agent. We showed that the private sector and congress play an important role in FTA negotiation in United States. In case of Mexico, the private sector and government occupy the dominant position in FTA negotiation. In particular, the cooperation of industry and government has been successfully established via COECE in Mexico. In contrast to these countries, the role of private participation in trade policy is relatively low in Japan and Korea.

• Journal of Electrochemical Science and Technology
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• 제8권4호
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• pp.294-306
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• 2017

Stainless steels and titanium alloys are widely used in the medical industry as replacement materials. These materials may be affected by the conditions and type of environment. In the same manner, soft drinks are widely consumed products. It is of interest for dental industry to know the behavior of medical-grade alloys when these are in contact with soft drinks, since any excessive ion release can suppose a risk for human health. In the present study, the electrochemical behavior of three stainless steel alloys and pure titanium was analyzed using three types of cola soft drinks as electrolyte. The objective of this study was to evaluate the response of these metallic materials in each type of solution (cola standard, light and zero). Different electrochemical techniques were used for the evaluation of the alloys, namely potentiodynamic polarization, linear polarization, and open-circuit potential measurements. The corrosion resistance of the stainless-steel alloys and titanium in the cola soft drinks was provided by the formation of a stable passive film formed by metal oxides. Scanning electron microscopy was used as a complementary technique to reveal corrosion phenomena at the surface of the materials evaluated.