• 대한지역사회영양학회지
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• 제9권1호
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• pp.81-89
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• 2004

A systematic review and meta-analysis of the literatures was conducted to evaluate the effectiveness of nutrition intervention by dietitian. The 31 studies that were all randomized controlled trials, were identified from computerized search of published researches on MEDLINE, Embase database until January, 2003 and review of reference lists. The main search terms were the combination “dietitian”, “dietary intervention”, “nutrition intervention” or “nutritional intervention” and “effectiveness”. The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention (nutritional counseling and education/nutrilion counseling and education + diet modification), method of intervention (individual/group/individual + group) and follow-up period. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The meta-analysis of 31 studies based on the random effect model showed that the medical nutrition therapy was significantly effective in treating the diseases (effect size 0.1715 : 95% confidence interval 0.0938-0.2491). This study showed the clear evidence of the effectiveness of nutrition intervention through the meta-analysis. So the nutrition intervention by dietitian should be recommended and recognized as the effective therapy of treating the diseases. Also the nutrition intervention should be conducted regularly to maintain the effectiveness of the nutrition intervention. The nutrition intervention was significantly effective in treating the diseases on the random effect model (effect size 0.1715 : 95% confidence interval 0.0938-0.2491).

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2635-2638
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• 2012

Background: Many studies have investigated the association between glutathione S-transferase T 1 (GSTT1) null genotype and risk of prostate cancer, but the impact of GSTT1 null genotype in Asians is still unclear owing to inconsistencies across results. Thie present meta-analysis aimed to quantify the strength of the association between GSTT1 null genotype and risk of prostate cancer. Methods: We searched the PubMed, Embase and Wangfang databases for studies of associations between the GSTT1 null genotype and risk of prostate cancer in Asians and estimated summary odds ratio (OR) with their 95% confidence interval (95% CI). Results: A total of 11 case-control studies with 3,118 subjects were included in this meta-analysis, which showed the GSTT1 null genotype to be significantly associated with increased risk of prostate cancer in Asians (random-effects OR = 1.49, 95% CI 1.15-1.92, P = 0.002), also after adjustment for heterogeneity (fixed-effects OR = 1.45, 95% CI 1.23-1.70, P < 0.001). No evidence of publication bias was observed. Conclusions: This meta-analysis of available data suggested the GSTT1 null genotype does contribute to increased risk of prostate cancer in Asians.

• Nutrition Research and Practice
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• 제5권5호
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• pp.464-470
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• 2011

Growing evidence suggests an elevated risk for colorectal neoplasia among individuals with low levels of vitamin D, the biological actions of which are mediated by the vitamin D receptor (VDR). To investigate the association among vitamin D status, VDR polymorphisms (FokI, and BsmI), and colorectal adenoma, we conducted a meta-analysis of nine studies of circulating levels of 25-hydroxyvitamin D (25(OH)D) and five studies of FokI or BsmI polymorphisms in relation to colorectal adenomas. Study-specific relative risks (RRs) and 95% confidence intervals (CIs) were pooled using a random-effects model. A total of 3398 coloreetal adenomas for 25(OH)D and 1754 colorectal adenomas for VDR were included in the meta-analysis. We identified a significant inverse association between colorectal adenoma (combined RR, 0.93; 95% CI, 0.87-0.98 per 10 ng/mL increase in 25(OH)D levels). When we examined FokI and BsmI polymorphisms in the meta-analysis, we found no association for either FokI (combined RR, 1.00; 95% CI, 0.95-1.06) or BsmI (combined RR, 0.99; 95% CI, 0.93-1.05) in the additive model. These data suggest an inverse association between circulating 25(OH)D levels and colorectal adenoma risk.

• 한방안이비인후피부과학회지
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• 제30권3호
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• pp.166-181
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• 2017

Objectives : The study was done to verify the relation between early-onset androgenetic alopecia(AGA) and metabolic syndrome(MetS). Methods : Data were collected through electronic database including KoreaMed, National Assembly Library, KMBASE, NDSL, KCI, KERIS, Google Scholar, Pubmed, Cochrane CENTRAL and EBSCO MEDLINE. A total of 13 case-control studies related to the MetS of early-onset alopecia patients were used for the systematic review and meta-analysis. Risk of bias of included studies were assessed by RoBANS tool. RevMan5.3, CMA3 were used for the meta-analysis. Results : In 13 evaluated articles, most frequent bias was the participant selection bias that was found in 10 articles. Significant association between early-onset AGA and MetS was found in 10(76.9%) out of 13 articles in the systematic review. In meta-analysis, early-onset male AGA was associated with increased risk of metabolic syndrome(OR: 3.73, 95% CI:2.49 -5.61). Conclusions : AGA, particularly early -onset male AGA, is significantly associated with MetS. Therefore all patients with early onset male AGA should be suggested to take preventive treatment to reduce the risk of MetS and various problems associated with it.

• 한국임상약학회지
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• 제29권4호
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• pp.247-253
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• 2019

Background: Glutamate is implicated in the pathophysiology of migraine, a common neurological disorder. Therefore, glutamate receptor antagonists (GluRAs) have been suggested as a novel migraine treatment that are able to overcome the limitations of triptans. Objective: The aim of this study was to perform a meta-analysis to assess the efficacy of GluRAs for patients with migraine. Method: The PubMed, Cochrane Library, CINAHL, and Clinical Trial.gov databases were searched for randomized placebo-controlled trials of the efficacy of GluRAs for patients with migraine conducted up to August 2019. Two independent reviewers screened the literature according to inclusion and exclusion criteria and performed quality assessment and data extraction. Review Manager 5.3 software was used for the meta-analysis. Results: Three studies involving a total of 206 patients were included in the final analysis. Compared with placebo, GluRAs significantly improved the pain-free response at 2 hours (odds ratio [OR]=3.85, 95% confidence intervals [CIs]=1.63-9.09) and the 24-hour sustained pain freedom (OR=7.40; 95% CIs=2.36-23.20). The use of rescue medications with GluRAs was lower compared to that with placebo, but the difference was not significant (OR=0.39, 95% CI=0.10-1.47). Conclusion: Our meta-analysis showed that GluRAs were more effective than placebo for patients with migraine.

• 정보처리학회논문지A
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• 제12A권4호
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• pp.289-296
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• 2005

그리드 환경에서 수행되는 작업 중 많은 작업들은 연관된 작업들이 서로 결합된 워크플로우의 형태로 수행된다. 이러한 워크플로우를 서비스로 추상화한다면 사용자는 보다 손쉽게 워크플로우로 구성된 작업을 수행할 수 있다. 본 논문에서는 워크플로우를 서비스로 매핑하기 위한 메타 서비스를 정의하였다. 이 메타 서비스를 사용하면 워크플로우를 포탈 서비스, 그리드 서비스, 웹 서비스 등으로 쉽게 변환할 수 있다. 또한 워크플로우 사용자들 간에 워크플로우를 서비스의 형태로 공유하는 것도 역시 가능해진다. 마지막으로 과거의 성능 데이터 등의 서비스를 효율적으로 수행할 수 있는 정보들을 제공하여 QoS를 향상시킬 수 있다.

• 대한한방내과학회지
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• 제42권3호
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• pp.259-278
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• 2021

Objectives: This study examines the effect of Sagunja-tang on functional dyspepsia (FD) through a systematic review and meta-analysis of a randomized controlled trial (RCT). Methods: A search for RCTs that tested the effect of Sagunja-tang on functional dyspepsia was conducted in Medline, Embase, PubMed, CENTRAL, CiNii, CNKI, NDSL, RISS, OASIS, and KISS databases on November 8, 2020, with no limit on the year of publication. A meta-analysis was performed by synthesizing the findings, including total efficiency, clinical symptom score, myosin light-chain kinase (MLCK) level (pg/mL, and gastric half-emptying time (min). RevMan 5.4.1 software was used for data analysis. The quality of the literature was evaluated using Cochrane's risk of bias (RoB) tool. Results: A total of 14 RCTs met the selection criteria. As a result of the meta-analysis, the treatment group had higher total efficacy and MLCK levels (gastric antrum, jejunum) than the control group, and the clinical symptom score and gastric half-emptying time were lower. However, due to the low quality of the included RCT and the small sample size, the results may be slightly biased.

• Smart Structures and Systems
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• 제32권2호
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• pp.123-133
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• 2023

This paper proposes a thermography-based coating thickness estimation method for steel structures using model-agnostic meta-learning. In the proposed method, a halogen lamp generates heat energy on the coating surface of a steel structure, and the resulting heat responses are measured using an infrared (IR) camera. The measured heat responses are then analyzed using model-agnostic meta-learning to estimate the coating thickness, which is visualized throughout the inspection surface of the steel structure. Current coating thickness estimation methods rely on point measurement and their inspection area is limited to a single point, whereas the proposed method can inspect a larger area with higher accuracy. In contrast to previous ANN-based methods, which require a large amount of data for training and validation, the proposed method can estimate the coating thickness using only 10- pixel points for each material. In addition, the proposed model has broader applicability than previous methods, allowing it to be applied to various materials after meta-training. The performance of the proposed method was validated using laboratory-scale and field tests with different coating materials; the results demonstrated that the error of the proposed method was less than 5% when estimating coating thicknesses ranging from 40 to 500 ㎛.

• 한국정보통신학회논문지
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• 제12권5호
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• pp.921-929
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• 2008

최근 데이터 통합을 위한 방안으로 데이터 이질성을 해결하기 위한 많은 연구가 진행되고 있다. 우리가 제안하는 시스템의 구성요소는 XMDR 래퍼와 XMDR 저장소이다. XMDR 래 퍼는 XMDR의 표준 정보를 기반으로 인터페이스를 생성하고, 표준 정보와 로컬스키마 간의 매핑정보를 이용하여 글로벌 XMDR 쿼리와 로컬 쿼리 간의 상호변환을 수행함으로써 기존 시스템의 이질성을 해결한다. XMDR 저장소는 표준 정보와 로컬간의 매핑정보를 관리하는 XMDR과 수행된 결과를 저장하는 Proxy DB로 구성되어 있다. 사용자는 동일한 인터페이스를 사용하고, XMDR 래퍼가 XMDR의 메타 시멘틱 온톨로지를 이용하여 스키마의 이질성을 해결뿐만 아니라 인스턴스 시멘틱 온톨로지를 통한 값의 의미에 따른 이질성도 고려함으로써 중복된 질의를 수행하지 않아도 된다. 따라서 본 논문에서는 이러한 데이터 이질성을 해결하고 효율적인 데이터 통합을 위한 데이터 그리드 래퍼를 제안한다.

• 정보관리연구
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• 제42권4호
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• pp.39-58
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• 2011

최신의 학술서비스 유형과 연구데이터 출판 및 서비스를 위한 DataCite 메타데이터 요소를 분석하여 OpenURL 학술서비스 유형을 기술하기 위한 메타태그를 Key/Encoded-Value(KEV) 형식으로 확장제안하였다. 현재의 OpenURL Z39.88 표준의 KEVFormat: Sch-Svc은 문헌중심의 학술서비스 유형 6가지만을 지원하고 있어 연구데이터의 원활한 유통을 위해서는 확장이 필요하다. 본 연구에서는 학술서비스 유형 분석을 위해 Scopus와 Web of Science, NDSL 서비스를 비교 검토하여 8개의 학술서비스 유형을 도출하였다. 또한 연구데이터 기술을 위한 DataCite 컨소시엄의 메타데이터 요소를 집중적으로 분석하여 9개의 대표속성을 도출하였다.