• 정보처리학회논문지D
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• 제16D권5호
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• pp.701-714
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• 2009

서비스 기반의 전사적 데이터 통합은 기업 변화의 가속화에 따른 통합적인 데이터 관리가 필요하다. 기업 간 협업은 비즈니스 프로세스를 이용하여 분산된 데이터베이스들에 접근하여 이루어진다. 이러한 접근은 글로벌 쿼리 기반으로 수행되기 때문에 이기종간의 상호운용을 위해서 데이터 이질성, 스키마 이질성, 유효성 검증과 같은 문제가 선결되어야 한다. 따라서 협업은 동적이면서 신뢰성 있는 구조를 갖추어야 한다. 본 논문에서는 협업을 위한 XMDR-DSM(eXtended MetaData Registry-Data Service Mediator) 시스템을 제안한다. XMDR-DSM은 XMDR-DS와 XMDR-DQP, XMDR-DAI로 구성되어 글로벌 스키마와 로컬 스키마간의 매핑을 지원해주고, 데이터 접근 및 통합 서비스를 제공한다. 따라서 이기종 데이터베이스 상호간의 업무 지원이 가능하게 하고, 정보를 재활용 가능한 자산으로 확보할 수 있는 이점과 교환의 표준화를 제시할 수 있다. 그리고 워크플로우 기반의 비즈니스 프로세스 제공할 수 있으므로 일원화된 정보를 관리할 수 있게 된다. 따라서 정보 수명을 증대하고 비용절감을 할 수 있게 된다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2407-2412
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• 2013

Background and Objectives: Data on associations between soy food intake after cancer diagnosis with breast cancer survival are conflicting, so we conducted this meta-analysis for more accurate evaluation. Methods: Comprehensive searches were conducted to find cohort studies of the relationship between soy food intake after cancer diagnosis and breast cancer survival. Data were analyzed with comprehensive meta-analysis software. Results: Five cohort studies (11,206 patients) were included. Pooling all comparisons, soy food intake after diagnosis was associated with reduced mortality (HR 0.85, 95%CI 0.77 0.93) and recurrence (HR 0.79, 95%CI 0.72 0.87). Pooling the comparisons of highest vs. lowest dose, soy food intake after diagnosis was again associated with reduced mortality (HR 0.84, 95%CI 0.71 0.99) and recurrence (HR 0.74, 95%CI 0.64 0.85). Subgroup analysis of ER status showed that soy food intake was associated with reduced mortality in both ER negative (highest vs. lowest: HR 0.75, 95%CI 0.64 0.88) and ER positive patients (highest vs. lowest: HR 0.72, 95%CI 0.61 0.84), and both premenopausal (highest vs. lowest: HR 0.78, 95%CI 0.69 0.88) and postmenopausal patients (highest vs. lowest: HR 0.81, 95%CI 0.73 0.91). In additioin, soy food intake was associated with reduced recurrence in ER negative (highest vs. lowest: HR 0.64, 95%CI 0.44 0.94) and ER+/PR+ (highest vs. lowest: HR 0.65, 95%CI 0.49 0.86), and postmenopausal patients (highest vs. lowest: HR 0.67, 95%CI 0.56 0.80). Conclusion: Our meta-analysis showed that soy food intake might be associated with better survival, especially for ER negative, ER+/PR+, and postmenopausal patients.

• 한국생활과학회지
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• 제17권4호
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• pp.785-796
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• 2008

The Open-Market internet shopping malls has rapidly been growing over the past few years. Thus, this study compares Meta-Mall and Open-Market, as well as evaluates image factors of the internet shopping mall in order to verify different levels of influence on customer satisfaction and revisit intentions. The subject of stud was made for students enrolled in colleges in the Busan area, using this Data collection method. Data were gathered using a questionnaire and through personal interviews from a sampling made from May 1 to May 8, 2008. The final 337 accomplished questionnaire forms were used for the subsequent analysis. The results of the substantial analysis are as follows. First, the following factors affect the image of internet shopping malls: assortment of goods and information service, site design, convenience, reliability of goods and information, and customer service. In Meta-Mall, these same factors, except customer service, were found to influence customer satisfaction, while in Open-Market, all the five factors were found to influence customer satisfaction. In Open-Market, convenience and reliability of goods and information had especially high levels of influence on customer satisfaction. Second, customer satisfaction with Internet shopping malls was found to influence the intentions of the customers to make a revisit. The result of the study shows that the factors of shopping mall image between Meta-Mall and Open-Market are perceived differently by their customers, and differences were found in the levels of their influence on customer satisfaction.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2605-2610
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• 2012

Background: Studies investigating the association of 2R/3R polymorphism in the thymidylate synthase 5'-untranslated enhanced region (TSER) and colorectal cancer (CRC) risk have reported conflicting results. Thus, a meta-analysis was performed to summarize the data on the potential association. Methods: Pubmed, Embase and CBM databases were searched for all available studies. Links between the TSER 2R/3R polymorphism and CRC risk were estimated by odds ratios (ORs) with 95% confidence intervals (CIs). Results: Seven case-control studies with a total of 2723 cases and 4030 controls were included in this meta-analysis. The results showed that the 3R variant of TSER 2R/3R polymorphism contributes to CRC risk in two comparison models (OR 3R vs. 2R =1.10, 95%CI 1.02-1.18, P = 0.015; OR Homozygote comparison model = 1.22 1.04-1.43, 95%CI 1.04-1.43, P = 0.012). Subgroup analyses by ethnicity further demonstrated a contribution in Caucasians with three comparison models (OR 3R vs. 2R = 1.10, 95%CI 1.02-1.19, P = 0.015; OR Homozygote comparison model = 1.21, 95%CI 1.03-1.41, P = 0.019; OR Recessive comparison model = 1.18, 95%CI 1.05-1.33, P = 0.008). However, the association in the Asian population was still uncertain due to the limited data (all P values were more than 0.05). Conclusions: Our meta-analysis suggests that the 3R variant of Thymidylate synthase 5'-untranslated enhanced region 2R/3R polymorphism contributes to gastric cancer risk in the Caucasian population, while any association in Asian populations needs further study.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.523-528
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• 2013

Background: The possibility that electromagnetic fields (EMF) exposure may increase male breast cancer risk has been discussed for a long time. However, arguments have been presented that studies limited by poor quality could have led to statistically significant results by chance or bias. Moreover, data fo the last 10 years have not been systematically summarized. Methods and Results: To confirm any possible association, a meta-analysis was performed by a systematic search strategy. Totals of 7 case-control and 11 cohort studies was identified and pooled ORs with 95% CIs were used as the principal outcome measures. Data from these studies were extracted with a standard meta-analysis procedure and grouped in relation to study design, cut-off point, exposure assessment method, adjustment and exposure model. A statistical significant increased risk of male breast cancer with EMF exposure was defined (pooled ORs = 1.32, 95% CI = 1.14-1.52, P < 0.001), and subgroup analyses also showed similar results. Conclusions: This meta-analysis suggests that EMF exposure may be associated with the increase risk of male breast cancer despite the arguments raised.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3123-3127
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• 2012

Objective: Experimental studies have suggested green tea to be a chemopreventive agent for colorectal cancer, and many studies have examined possible associations. However, the conclusions were inconsistent or even contradictory, so we performed a meta-analysis based on published case-control studies to explore if green tea is indeed a protective factor. Methods: PubMed was searched up to May $10^{th}$, 2012 for relevant studies, and references of included studies were manually searched. Finally 13 eligible studies, involving 12,636 cases and 38,419 controls were identified. After data extraction, a meta-analysis was performed using CMA v2 software. Results: The results indicated there may be a weak but not statistically significant reduced risk of colorectal cancer with high dose of green tea intake (OR=0.95, 95% CI:0.81-1.11, p=0.490.69-0.98). This protective effect was also found in all subgroups, except in American and European populations. Sensitivity analysis indicated the result to be robust. Publication bias was not detected by either funnel plot or Egger tests. Conclusion: The results of this meta-analysis indicate a weak lower tendency for colorectal cancer development with green tea consumption, but available epidemiologic data are insufficient to conclude that green tea may protect against colorectal cancer in humans.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4785-4790
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• 2013

Background and Objectives: Evidence for associations between alcohol consumption with breast cancer survival are conflicting, so we conducted the present meta-analysis. Methods: Comprehensive searches were conducted to find cohort studies that evaluated the relationship between alcohol consumption with breast cancer survival. Data were analyzed with meta-analysis software. Results: We included 25 cohort studies. The meta-analysis results showed that alcohol consumption was not associated with increased breast cancer mortality and recurrence after pooling all data from highest versus lowest comparisons. Subgroup analyses showed that pre-diagnostic or post-diagnostic consumpotion, and ER status did not affect the relationship with breast cancer mortality and recurrence. Although the relationships of different alcohol consumption with breast cancer mortality and recurrence were not significant, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence. Only alcohol consumption of >20 g/d was associated with increased breast cancer mortality, but not with increased breast cancer recurrence. Conclusion: Although our meta-analysis showed alcohol drinking was not associated with increased breast cancer mortality and recurrence, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence and alcohol consumption of >20 g/d was associated with increased breast cancer mortality.

• 한국콘텐츠학회논문지
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• 제16권1호
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• pp.391-402
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• 2016

본 연구는 유아교사의 교사효능감과 직무만족의 상관관계를 고찰할 수 있는 연구방법인 메타분석(mata-analysis)의 방법으로, 유아교사의 교사효능감과 직무만족 간의 효과크기 및 두 변수의 하위변수 간 효과크기를 살펴보는 것을 연구목적으로 하였다. 이러한 연구목적을 위해 메타분석 전용 프로그램인 CMA(Comprehensive Meta Analysis) 2.0을 분석에 적용하였다. 분석결과, 유아교사의 교사효능감과 직무만족의 관계는 Cohen(1992)의 기준으로 중간 효과크기보다 높게 나타났다. 교사효능감 하위변수 중에서는 개인 교수효능감이 일반 교수효능감보다 직무만족의 관계에서 높은 효과크기를 보였으며, 직무만족의 하위변수 중에서는 직무자체 신념이 교사효능감의 관계에서 효과크기가 가장 높았다. 조절변수인 논문유형에서는 박사 학위논문이 효과크기가 높았으며, 출판연도와 표본 수는 메타회귀분석 결과, 통계적으로 유의하지 않았다. 이상의 분석결과를 기초로 하여 논의와 연구의 한계점을 제시하였다.

• 한방안이비인후피부과학회지
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• 제30권3호
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• pp.1-19
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• 2017

Objectives : This study aimed to validate the effect of herbal medicine intervention to relieve the symptoms of psoriasis using systematic review and meta-analysis and provide the newest reason of effectiveness of Korean medicine to psoriasis. Methods : Data were collected through electronic database including Pubmed, Cochrane CENTRAL, NDSL OASIS, Koreantk. Two experts assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool after searching, reviewing and selecting papers. Data were analyzed using Review Manager(RevMan) 5.3 and Comprehensive Meta Analysis 2.0. Results : Total number of selected trials was 16 randomized controlled trials. This study evaluated the risk of bias and effectiveness of herbal medicine to psoriasis. There were high frequency uncertain in selection bias, performance bias and detection bias. In this meta-analysis, Korean medicine treatment was more effective than western medicine (ES:0.507, 95%CI:0.147-0.867) and placebo (ES:0.955, 95%CI:0.598-1.312). Conclusions : Herbal medicine intervention can be an effective for treatment in psoriasis. But enhancing levels of evidence, we must try to accumulate clinical researches of herbal medicine to psoriasis in Korea.

• Journal of Ginseng Research
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• 제40권3호
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• pp.269-277
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• 2016

Background: The findings of currently available studies are not consistent with regard to the association between the risk of cancer and ginseng consumption. Therefore, we aimed to evaluate this association by conducting a meta-analysis of different studies. Methods: To systematically evaluate the effect of ginseng consumption on cancer incidence, six databases were searched, including PubMed, Ovid Technologies, Embase, The Cochrane Library, China National Knowledge Infrastructure, and Chinese VIP Information, from 1990 to 2014. Statistical analyses based on the protocol employed for a systematic review were conducted to calculate the summary relative risks (RRs) and 95% confidence intervals (CIs). Results: We identified nine studies, including five cohort studies, three case-control studies, and one randomized controlled trial, evaluating the association between ginseng consumption and cancer risk; these studies involved 7,436 cases and 334,544 participants. The data from the meta-analysis indicated a significant 16% lower risk of developing cancer in patients who consumed ginseng (RR = 0.84, 95% CI = 0.76-0.92), with evidence of heterogeneity (p = 0.0007, $I^2$ = 70%). Stratified analyses suggested that the significant heterogeneity may result from the incidence data for gastric cancer that were included in this study. Publication bias also showed the same result as the stratified analyses. In addition, subgroup analyses for four specific types of cancer (colorectal cancer, lung cancer, gastric cancer, and liver cancer) were also performed. The summary RRs for ginseng intake versus no ginseng consumption were 0.77 for lung cancer, 0.83 for gastric cancer, 0.81 for liver cancer, and 0.77 for colorectal cancer. Conclusion: The findings of this meta-analysis indicated that ginseng consumption is associated with a significantly decreased risk of cancer and that the effect is not organ specific.