• The Journal of the Korea Contents Association
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• v.15 no.5
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• pp.254-264
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• 2015

This study was done for analyzing the effects of menopausal women's life stress on life satisfaction and depression. The subjects of this study were 425 menopausal women in Daejeon Metropolitan City and Chungnam Province. Data were analyzed using descriptive statistics, t-test, ANOVA, Scheffe's test, Pearson correlation coefficients and stepwise multiple regression with the SPSS 19.0 program. Life stress differed according to marital status, income, climacteric symptoms level. Also the findings indicate that there is a significant positive correlation between life stress and life satisfaction. However, there is negative effect of life stress on depression. The results of this study offer basic data for the development of counseling and social support program to reduce depression and improve the life satisfaction for menopausal women. Also integrated programs and capacity-building programs were suggested to prepare the elderly life.

• Korean Journal of Human Ecology
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• v.23 no.6
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• pp.1105-1126
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• 2014

The purpose of this study was to explore the factors related to depression of married baby-boomer female by employment status. Data for this study was based on a convenience sample of 499 married female baby-boomer who have residence in Busan and Gyeongnam province. The prevalence rate of depression symptoms was 21.4%. The employment status made differences on the factors related to depression of married female baby boomers. Depressive symptoms were significantly associated with attitudes toward menopause, menopausal symptoms and marital satisfaction for both baby-boomer female with and without a job. While monthly household income, participation in voluntary associations and satisfaction with children were significantly related to depression symptoms of baby-boomer female without employment, perimenopausal stage, perceived size of social network was important factors for the depression of married female baby boomers with a job.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.22 no.3
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• pp.258-267
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• 2015

Purpose: The purpose of study was to compare depression, marital intimacy, sexual function and quality of life between a group of sexually active women and a group of women who were sexually inactive. All of the women were post-menopausal married women. Methods: Post-menopausal married women (n=395) of 40 to 59 years old participated in the study. Data were collected through self-report questionnaires which included items on general characteristics, and tools on depression (CES-D), marital intimacy (MIQ), sexual function (FSFI), and quality of life. Data were analyzed using descriptive statistics, t-test, $X^2-test$, ANCOVA, and Pearson correlation coefficients. Results: About 42% of the participants were identified as sexually inactive. Marital intimacy, sexual function, and quality of life in the sexually active group were significantly higher than the inactive group (F=17.12, p<.001; F=36.86, p<.001; F=16.78, p<.001). Depression scores in the sexually active group were significantly lower than in the inactive group (F=14.64, p<.001). Also, there was a significant relationship of depression, marital intimacy, and sexual function to quality of life in both groups. Conclusion: The results of this study indicate that health professionals need to counsel and provide a psychosexual approach especially when caring for post-menopausal married women who are sexual inactive.

• Journal of Convergence for Information Technology
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• v.10 no.3
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• pp.31-37
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• 2020

The study was investigate the effect of Climacteric Symptom and Self Esteem on depression in middle woman. A questionnaire was completed by 125 D & S city middle aged womans from January to February 2019. data was analyzed using SPSS/WIN 21.0. In addition descriptive statistics and t-test, ANOVA and Pearson's correlation coefficients and multiple regression were used in the data analysis. Differences in depression according to general characteristics of middle-aged women showed significant difference in economic status and health status instability. The variables affecting depression are Climacteric Symptom(β=.409, p<.001), Self Esteem(β=-.368 p<.001), economic status(β=.067 p=353), health status(β=-.094 p=.174). It should be used in the development of social policy nursing policy for menopausal women by confirming the symptoms of menopausal symptoms and depression in middle-aged women and accepting menopausal period as a turning point of natural life.

• Korean Journal of Pharmacognosy
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• v.51 no.4
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• pp.310-316
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• 2020

Kyung-Ok-Go (KOK) is a traditional prescription used for debilitating natural aging and post-illness debilitation. KOK has been used in a variety of ways because it strengthens immunity, prevents illness, and helps recovery in case of illness. In particular, recent research has revealed that KOK helps improve memory and cognition. Therefore, in this study, we investigated whether KOK was effective in improving memory decline and depression-state observed during menopause. In the present study, we employed ovariectomized mouse as an animal model for measuring menopausal syndrome. The administration of KOK for 8 weeks, the object recognition memory and working memory were improved in novel object recognition test and Y-maze test. And in the forced swimming test, the immobility time were decreased. Additionally, the expression level of mature brain derived neurotropic factor (mBDNF) was increased by KOK administration in ovariectomized mouse hippocampus. These results suggested that KOK could improve cognitive decline and depression during menopausal period, and it might be come from enhancing expression level of mBDNF in hippocampus.

• Korean Journal of Biological Psychiatry
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• v.16 no.4
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• pp.229-237
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• 2009

Recent Korean statistics show that a Korean woman can now expect to live until her mid-80s, which implies living at least one-third of her life after menopause. The menopausal transition is typically marked by intense hormonal fluctuations, accompanied by sleep disturbance, vasomotor symptoms(e.g., hot flashes, night sweats), increased risk for osteoporosis, cardiovascular disease, and developing depression as well as mood disturbances. These symptoms can affect a woman's quality of life negatively. Therefore, a comprehensive understanding of the accurate detection and appropriate treatment of various menopause-related symptoms including depression in the menopausal transitions and postmenopause is mandatory. This review primarily focused on the current knowledge about the treatment of menopause-related depression.

• Journal of Oriental Neuropsychiatry
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• v.20 no.4
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• pp.149-159
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• 2009

Objectives : This study was performed to report the effect of Korean traditional treatments for Hwa-Byung with menopausal symptoms. Methods : In this case, a 48 years old female patient has been suffered by Hwa-Byung with menopausal symptoms for 3 years old. We treated the patient with Korean traditional treatments (acupuncture, herb-medication and aroma theraphy), mindfulness and Korean traditional psychotherapy. The effects of treatment were measured by Beck Depression Inventory(BDI), Zung Depression Rating Scale(SDS), Kupperman Index(KI), Menopause Rating Scale(MRS). Results : After treatment, the chief complaints and accompanying symptoms were subsided and improved. And BDI, SDS, KI and MRS score were decreased. Conclusions : According to this study, the Korean traditional treatment such as acupuncture, herb-medication is effective for the cure of Hwa-Byung with menopausal symptoms.

• Korean Journal of Biological Psychiatry
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• v.12 no.2
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• pp.173-180
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• 2005

Purpose:We investigated the effect of menopausal duration on cognitive function using adjunctive hormone replacement therapy(HRT) in postmenopausal women with depression. Method:Twelve postmenopausal women with depressive disorder were enrolled. Six patients having menopausal duration of less than 3 years was assigned to the short duration group and six patients of more than 3 years to the long duration group. Each patient was treated with conjugated equine estrogen(1.25mg) plus medroxyprogesterone(5mg) for 8 weeks. Cognitive performance was measured by the Verbal Memory Test, Visual Memory Test, Trail Making Test, Digit Symbol Test, and Attention Shift Test. The Beck Depression Inventory was used for evaluation of depressed mood. The reproductive hormone levels were also measured. Results:The long duration group showed the lower performance only in Trail Making Test B compared with the short duration group at baseline. After 8 weeks, the long duration group performed significantly better in the Trail Making Test B compared with the short duration group. The differences in change of depressive mood and gonadal hormone level between two groups were not significant. Conclusion:Menopausal duration before HRT may influence the effect of estrogen on cognition in some cognitive domains. This might be related with estrogen receptor hypersensitivity which induced by the longer estrogen deficiency.

• Journal of Menopausal Medicine
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• v.24 no.3
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• pp.183-187
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• 2018

Objectives: The present mini review aimed to summarize the existing knowledge regarding the beneficial and adverse effects of raloxifene in menopausal women. Methods: This study is a review of relevant publications about the effects of raloxifene on sleep disorder, depression, venous thromboembolism, the plasma concentration of lipoprotein, breast cancer, and cognitive function among menopausal women. Results: Raloxifene showed no significant effect on depression and sleep disorder. Verbal memory improved with administration of 60 mg/day of raloxifene while a mild cognitive impairment risk reduction by 33% was observed with administration of 120 mg/day of raloxifene. Raloxifene was associated with a 50% decrease in the need for prolapse surgery. The result of a meta-analysis showed a significant decline in the plasma concentration of lipoprotein in the raloxifene group compared to placebo (standardized mean difference, -0.43; 10 trials). A network meta-analysis showed that raloxifene significantly decreased the risk of breast cancer (relative risk, 0.572; 95% confidence interval, 0.327-0.881; P = 0.01). In terms of adverse effects of raloxifene, the odds ratio (OR) was observed to be 1.54 (P = 0.006), indicating 54% increase in the risk of deep vein thrombosis (DVT) while the OR for pulmonary embolism (PE) was 1.05, suggesting a 91% increase in the risk of PE alone (P = 0.03). Conclusions: Raloxifene had no significant effect on depression and sleep disorder but decreased the concentration of lipoprotein. Raloxifene administration was associated with an increased risk of DVT and PE and a decreased risk of breast cancer and pelvic organ prolapse in postmenopausal women.

• The Journal of Korean Obstetrics and Gynecology
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• v.31 no.1
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• pp.138-146
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• 2018

Objectives: The purpose of this study is to evaluate the effects of Gamiguibi-hwan on Climacteric Syndrome. Method: We treated 50 cases menopausal disorder patients with Gamiguibi-hwan for 12 weeks. We estimated the effects by Menopause Rating Scale (MRS), Pittsburgh Sleep Quality Index (PSQI) and Beck's Depression Inventory II (BDI-II). Results: After treatment, the mean of MRS, PSQI and BDI-II score were decreased. Conclusions: This case shows that Gamiguibi-hwan is effective in treating menopausal disorder patients.