• Journal of The Korean Society of Integrative Medicine
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• v.7 no.1
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• pp.47-56
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• 2019

Purpose: The present study confirms the content validity and understanding level of the questions of the Korean version of caries management by risk assessment (CAMBRA). Methods: To develop the Korean version of CAMBRA for children aged 0-5 years, a series of steps were followed: first, translation and reverse-translation processes were conducted by an expert committee. To establish content validity, CAMBRA was modified to adapt to the conditions in Korea by 17 dental hygiene professionals with a master's or a higher degree. The responses were analyzed using analysis of frequency and descriptive statistics. Content validity was verified by calculating the content validity index (CVI). The survey was administered to 64 mothers and caregivers to assess the understanding level of questions of the Korean version of CAMBRA. Results: Content validity of each of the items showed an S-CVI/AVE value of 0.79, but the content validities varied from 0.63 to 1.0. The understanding level of each question was between 3.56 and 4.46, thus showing favorable results. Conclusion: It was concluded that the test items verified for content validity were suitable for assessing caries risk for children of ages 0-5 years. This study would contribute to improving children's oral health and disease prevention by providing timely intervention.

• Transactions on Electrical and Electronic Materials
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• v.13 no.6
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• pp.310-316
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• 2012

A new method for early caries diagnosis was proposed and tested through a home-made optical examination system that used quantitative light fluorescence (QLF) and digital imaging fiber optic transillumination (FOTI) (DIFOTI), with light sources across a wide spectral range, from 350 nm to 1,000 nm. The front-illuminated infrared light scattering image (FIR) showed similar diagnostic abilities to that of DIFOTI. The FIR method was invented based on the observation that caries lesions lose the high transmittance and low scattering properties of benign enamel tissue. There are various methods for the early diagnosis of caries, such as visual examination, exploration, X-ray radiography, QLF, FOTI, and infrared fluorescence (diagnodent). Among them, methods based on optical properties are regarded as having the most potential. A comparative study was performed between the FOTI, QLF, diagnodent, optical coherence tomography, and FIR scattering image methods, using 20 extracted teeth samples with early caries. A scale of lesion measurement based on optical image contrast was proposed. The statistical analysis showed a significant correlation between the DIFOTI and FIR methods (r = 0.35, p < 0.05). However, the QLF and diagnodent methods showed little association with FIR images, as they have different detection principles as compared with FIR. Tomographic images obtained by OCT, using 1,330 nm super luminescent LED as a gold standard of tooth structure, verified that the FOTI and FIR results correctly represented the lack of homogeneity in dental tissue. The newly proposed FIR method attained similar diagnostic results to those of FOTI, but with an easier approach.

• Journal of Korean society of Dental Hygiene
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• v.16 no.1
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• pp.45-52
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• 2016

Objectives: The purpose of the study was to investigate the cumulative dental caries rate of pit and fissure sealant in community public health program from 2005 to 2008 follow-up. Methods: The subjects were 4,768 students of 34 elementary schools in Gimcheon. The survey included direct oral examination and cumulative retention rate of pit and fissure sealant from 2005 to 2008. Data were analyzed using PASW statistical package version 18.0 and the level of significance was set at p<0.05. Results: The cumulative retention rate of sealant was 18%, 25%, and 33% after 1 year, 2 years, and 3 years, respectively. In addition, the cumulative retention rate of lower teeth was higher than that of upper teeth. Cumulative dental caries rate increased in sealed group and no sealed group. The cumulative dental caries rate decreased owing to tooth brushing frequency in sealed group and no sealed group. Conclusions: Regular and timely tooth brushing can maintain good oral health condition after tooth sealing. The school based oral health education can prevent loss of sealant and secondary caries.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.5
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• pp.854-858
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• 2010

Streptococcus mutans (S. mutans) plays an important role in the information of dental plaque and it is being noticed as major causative bacteria of dental caries. In the present study, inhibitory effects of the ethanol extract of Dianthus superbus Linne (D. superbus) on the growth, acid production, adhesion and water-insoluble glucan synthesis of S. mutans were examined. The ethanol extract of D. superbus (0.5 - 4 mg/ml) significantly lowered the growth of S. mutans in a dose dependent manner. The acid production of S. mutans were inhibited by the presence of ethanol extract of D. superbus(1 - 4 mg/ml) significantly. The ethanol extract of D. superbus (0.25 - 4 mg/ml) also significantly lowered the adherence of S. mutans in a dose dependent manner. In water-insoluble glucan synthesis assay, 0.25 - 4 mg/ml of the ethanol extract of D. superbus significantly inhibited the formation of water-insoluble glucan. These results suggest that D. superbus may inhibit the caries-inducing properties of S. mutans. Further studies are necessary to clarify the active constituents of D. superbus responsible for such biomolecular activities.

• Journal of Dental Anesthesia and Pain Medicine
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• v.19 no.6
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• pp.313-322
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• 2019

Early childhood caries is a global healthcare concern in developing and industrialized countries. If left untreated, it leads to immediate and long-term complications that affect the well-being and quality of life of concerned families. Therefore, many preventive and treatment approaches are available to the healthcare provider to curb this virulent form of caries. After behavioral interventions, general anesthesia is used in specific settings when a young patient presents with extensive teeth damage and exhibits a lack of cooperation that is incompatible with conventional dental office care. However, without proper follow-up, any positive results might be lost over time.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.2
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• pp.370-374
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• 2005

Streptococcus mutans (S. mutans) is known as the causative bacterial playing the most important role informing plaque and it is being noticed as major causative bacteria of dental caries. Therefore, development of more effective, substantial and safe preventive agent against dental caries and periodontal disease is honestly required. The present study was designed to investigate the effect of Cyperus rotundus (Cyperaceae) methanol extracts on the growth, acid production, adhesion, and insoluble glucan synthesis of S. mutans. The methanol extract of C. rotundus showed concentration dependent inhibitory activity against the growth and acid production of S. mutans, and produced significant inhibition at the concentration of 0.5, 1, 2 and 4 mg/ml compared to the control group. The extracts markedly inhibited S. mutans adherence to HA treated with saliva, and cell adherence was repressed by more than 50% at the concentration of 0.5 mg/ml and complete inhibition was observed at the concentration of 4 mg/ml. On the activity of glucosyltransferase which synthesizes water insoluble glucan from sucrose, methanol extract of C. rotundus showed more than 10% inhibition over the concentration of 2 mg/ml. Thus, the application of C. rotundus can be considered a useful and a practical method for the prevention of dental caries.

• Imaging Science in Dentistry
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• v.47 no.2
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• pp.109-115
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• 2017

Purpose: The aim of this study was to assess the ex vivo diagnostic ability of 9 different cone-beam computed tomography (CBCT) settings in the detection of recurrent caries under amalgam restorations in primary teeth. Materials and Methods: Fifty-two primary teeth were used. Twenty-six teeth had dentine caries and 26 teeth did not have dentine caries. Black class II cavities were prepared and restored with amalgam. In the 26 carious teeth, recurrent caries were left under restorations. The other 26 intact teeth that did not have caries served as controls. Teeth were imaged using a $100{\times}90-mm$ field of view and a 0.2-mm voxel size with 9 different CBCT settings. Four observers assessed the images using a 5-point scale. Kappa values were calculated to assess observer agreement. CBCT settings were compared with the gold standard using a receiver operating characteristic analysis. The area under the curve (AUC) values for each setting were compared using the chi-square test, with a significance level of ${\alpha}=.05$. Results: Intraobserver kappa values ranged from 0.366 to 0.664 for observer 1, from 0.311 to 0.447 for observer 2, from 0.597 to 1.000 for observer 3, and from 0.869 to 1 for observer 4. Furthermore, interobserver kappa values among the observers ranged from 0.133 to 0.814 for the first reading and from 0.197 to 0.805 for the second reading. The highest AUC values were found for setting 5 (0.5916) and setting 3 (0.5886), and were not found to be statistically significant(P>.05). Conclusion: Variations in tube voltage and tube current did not affect the detection of recurrent caries under amalgam restorations in primary teeth.

• The Korean Journal of Health Service Management
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• v.7 no.2
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• pp.179-190
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• 2013

This study evaluated the interest of parents of elementary school children on the examination with their memory of results, their consistency and their compliance with results sheets to improve effects of School dental health management project. This study recruited 1,334 second-, third-, fifth- and sixth-grade students at two elementary schools located in Daegu metropolitan city performing School Dental Examination Project in 2008 and investigated whether the students visited dental hospitals following results of the examination, how the parents remembered the results and how their memory was same with real results based on results of the examination, the parents' memory of results. The parents of second- and third-grade students showed good memory of malocclusion and number of Caries and higher consistency for dental caries. The parents of fifth- and sixth-grade students showed good memory of dental caries. Visiting rates of dental hospitals accordance with grade were 75.7% due to dental caries in second- and third-grade students and 60.5% due to malocclusion in fifth- and sixth-grade students. Among students with abnormal results of the examination, 77.1% of the children with dental caries of parents having same memory with real results visited the hospitals while 52.7% of those of parents having different memory with them did.

• Journal of Korean society of Dental Hygiene
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• v.15 no.2
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• pp.311-317
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• 2015

Objectives: The purpose of this study was to identify the effects of xylitol and sorbitol mouth rinse on the salivary caries activity levels. Methods: The study subjects were 38 female college students in Gyeongju, Korea. The subjects visited the institution once a week for 4 weeks and the saliva samples were measured for the amount of salivary caries activity levels. The saliva was collected 5 times and incubated in Mitis Salivarius Agar for 48 hours(VS-1203P3L, Vision, Korea) and measured. Results: The Streptococcus mutans CFU decreased by statistically significant amounts as compared to before the experiment within the xylitol group and the sorbitol group(p<0.01). After three weeks of mouth rinse application, Streptococcus mutans CFU of the xylitol group and the sorbitol group showed statistically significant differences(p<0.05). The salivary flow rates within the xylitol group and sorbitol group increased by statistically significant amounts(p<0.01) than before the test. The change in the salivary buffering capacity decreased by a statistically significant amount as compared to before experiment within the xylitol group(p<0.01). Conclusions: The salivary caries activity levels decreased after using xylitol and sorbitol mouth rinse in CFU and the flow rate. The buffering activity levels increased within the xylitol group. Further follow-up studies would be necessary to identify the various effects of xylitol.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1625-1628
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• 2006

The (-)-pimara-9 (11), 15-dien-19-oic acid, acanthoic acid was extracted from the roots of Acanthopanax koreanum using bioassay-guided isolation of a MeOH extract. Acanthoic acid was assayed against Streptococcus mutans and Staphylococcus epidermidis causing dental caries and opportunistic pathogen. The minimum inhibitory concentration (MIC) of acanthoic acid against Streptococcus mutans and Staphylococcus epidermidis was 2 and 4 ${\mu}g/mL$, respectively, which was much lower than those of other natural antimicrobial agents such as 8 ${\mu}g/mL$ of tanshinone IIA. Acanthoic acid also significantly inhibited the growth of other cariogenic bacteria such as Streptococcus sobrinus and Streptococcus sanguis, and Streptococcus grodenii in the MIC range of 4${\sim}$32 ${\mu}g/mL$. Our findings suggest that acanthoic acid could be employed as a potential antibacterial agent for preventing dental caries and skin infections.