• Communications for Statistical Applications and Methods
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• v.7 no.2
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• pp.549-562
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• 2000

Default Bayes factors are computed to test the equality of one Poisson population mean and the equality of two independent Possion population means. As default priors are assumed Jeffreys priors, noninformative improper priors, and default Bayes factors such as three intrinsic Bayes factors of Berger and Pericchi(1996, 1998), the arithmetic, the median, and the geometric intrinsic Bayes factor, and the factional Bayes factor of O'Hagan(1995) are computed. The testing results by each default Bayes factor are compared with those by the classical method in the simulation study.

• Journal of fish pathology
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• v.20 no.2
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• pp.161-167
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• 2007

Acute toxicity of formalin (37% formaldehyde) was conducted to determine the median lethal concentration (LC50) on eel (avarage weight 96 ± 3.6 g, average total length 43 cm), Anguilla japonica at concentrations ranging from 0 to 500 ppm. In particular, this study was designed to estimate the safety concentrations of formalin in testing eels to eradicate Pseudodactylogyrus. All fish died after 10 hours and 24 hours at 500 ppm and 400 ppm, respectively. After 24 hours, cumulative mortality was 96.6% and 13.3% at 300 ppm and 200 ppm formalin, respectively. However, all experimental fish were alive after 24 hours at 100 ppm. The lethal concentration values were computed by using non-linear least square method. At the start of the test, water temperature, pH and dissolved oxygen level were 27～28℃, 7.4 and 5.55 ppm, respectively. The 24 hr-LC50 were 269 ppm.

• Radiation Oncology Journal
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• v.32 no.3
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• pp.125-131
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• 2014

Purpose: We reviewed treatment outcomes and prognostic factors for patients with salivary ductal carcinoma (SDC) treated with surgery and postoperative radiotherapy from 2005 to 2012. Materials and Methods: A total of 16 patients were identified and 15 eligible patients were included in analysis. Median age was 61 years (range, 40 to 71 years) and 12 patients (80%) were men. Twelve patients (80%) had a tumor in the parotid gland, 9 (60%) had T3 or T4 disease, and 9 (60%) had positive nodal disease. All patients underwent surgery and postoperative radiotherapy. Postoperative radiotherapy was delivered using 3-dimensional conformal radiotherapy or intensity-modulated radiotherapy. Locoregional failure-free survival (LRFFS), distant failure-free survival (DFFS), progression-free survival (PFS), and overall survival (OS) were calculated using the Kaplan-Meier method. Differences in survival based on risk factors were tested using a log-rank test. Results: Median total radiotherapy dose was 60 Gy (range, 52.5 to 63.6 Gy). Four patients received concurrent weekly chemotherapy with cisplatin. Among 10 patients who underwent surgery with neck dissection, 7 received modified radical neck dissection. With a median follow-up time of 38 months (range, 24 to 105 months), 4-year rates were 86% for LRFFS, 51% for DFFS, 46% for PFS, and 93% for OS. Local failure was observed in 2 patients (13%), and distant failure was observed in 7 (47%). The lung was the most common involved site of distant metastasis. Conclusion: Surgery and postoperative radiotherapy in SDC patients resulted in good local control, but high distant metastasis remained a major challenge.

• Journal of The Korean Society of Clinical Toxicology
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• v.9 no.2
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• pp.49-55
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• 2011

Purpose: Acetanilide has been in widespread use as an amide herbicide compound. However, available data regarding acute human poisoning is scarce. The aim of this study was to analyze the clinical characteristics of acetanilide poisoning in order to identify the risk factors associated with severity. Methods: We conducted a retrospective observational study encompassing the period January 2005 to December 2010, including adult ED patients suffering from acetanilide intoxication. Toxicological history, symptoms observed, clinical signs of toxicity, and laboratory test results were collected for each patient. The patients were classified into two groups for analysis, according their poisoning severity score (PSS). Resulting clinical data and prognostic variables were compared between mild-to-moderate poisoning (PSS 1/2 grades), and severe poisonings and fatalities (PSS 3/4 grades). Results: There were a total of 37 patients, including 26 alachlor, 6 s-metolachlor, 4 mefenacet, and 1 butachlor cases. The majority of patients (81.1%) were assigned PSS 1/2 grades. Changes in mental status and observation of adverse neurologic symptoms were more common in the PSS 3/4 group. The median ingested volume of amide herbicide compound was 250 ml (IQR 200-300 ml) in the PSS 3/4 group, and 80 ml (IQR 50-138 ml) in the PSS 1/2 group. Also, the median GCS observed in the PSS 3/4 group was 13 (IQR 10-14), which was markedly low as compared to a median GCS of 15 in the PSS 1/2 group. Overall mortality rate was 5.4%, and profound cardiogenic shock was observed prior to death in all fatalities. Conclusion: When compared to previous reports, acute acetanilide poisoning resulted in relatively moderate severity. The presence of neurologic manifestations, hypotension, lower GCS score, and larger ingested volumes was associated with more serious effects and mortalities.

• Smart Structures and Systems
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• v.14 no.4
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• pp.719-741
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• 2014

Monitoring surface cracks is important to ensure the health of concrete structures. However, traditional visual inspection to monitor the concrete cracks has disadvantages such as subjective inspection nature, associated time and cost, and possible danger to inspectors. To alter the visual inspection, a complete procedure for automated crack assessment based on adaptive digital image processing has been proposed in this study. Crack objects are extracted from the images using the subtraction with median filter and the local binarization using the Niblack's method. To adaptively. determine the optimal window sizes for the median filter and the Niblack's method without distortion of crack object an optimal filter size index (OFSI) is proposed. From the extracted crack objects using the optimal size of window, the crack objects are decomposed to the crack skeletons and edges, and the crack width is calculated using 4-connected normal line according to the orientation of the local skeleton line. For an image, a crack width nephogram is obtained to have an intuitive view of the crack distribution. The proposed procedure is verified from a test on a concrete reaction wall with various types of cracks. From the crack images with different crack widths and patterns, the widths of cracks in the order of submillimeters are calculated with high accuracy.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.15 no.1
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• pp.38-43
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• 2012

Purpose: Epstein-Barr virus (EBV) hepatitis is a usually asymptomatic and self-limiting disease in immunocompetent patients. However, the range of severity is wide, and the serological diagnosis is typically difficult until the convalescent phase. Thus, we examined the value of plasma EBV DNA real-time quantitative polymerase chain reaction (RT-qPCR) in EBV hepatitis for the timely diagnosis and the relationship between EBV viral load and clinical severity. Methods: Sixty samples were confirmed as having EBV infection by RT-qPCR with the EBV BALF5 gene sequence. We examined the clinical characteristics of EBV hepatitis by reviewing medical records. Results: The median total duration of fever was 8 days (range: 0-13 days). The mean peak value of aspartate aminotransferase (AST) was $241{\pm}214$ U/L, and the mean peak value of alanine aminotransferase (ALT) was $298{\pm}312$ U/L. There was no correlation between the serum levels of liver enzyme and plasma EBV DNA titer ($p$=0.1) or between median total duration of fever and EBV DNA titer ($p$=0.056). The median age of the EBV VCA IgM-negative group was lower compared with the EBV VCA IgM-positive group in EBV hepatitis (2 years vs. 6 years, $p$=0.0009). Conclusion: The severity of EBV hepatitis does not correlate with circulating EBV DNA load according to our data. Furthermore, we suggest that plasma EBV PCR may be valuable in young infants in whom the results of serology test for EBV infection commonly are negative.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.3
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• pp.585-590
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• 2012

Coronary Intervention treatment has become the core that is the test of cardiac catheterization to conduct treatment with Coronary Arteriography. Operators must be careful in Coronary Intervention treatment because the stent is inserted into the point of narrowing of blood vessel. So, the operator must correctly recognize the path of blood vessel to deal with the problems which are damages and ruptures of blood vessel, and there would be some errors of finding the path of blood vessel by bad qualify of the image. Therefore in this paper, median filtering is conducted by preprocessing to evaluate the performance of the effect of noise of the image that affects quality of the image and Fuzzy Edge Extraction Techniques is tested by using Soble Edge Extraction Techniques to compare the performance with The Fuzzy Edge Extraction Techniques. In result, the performance, removing the noise and extracting the signal of Fuzzy Edge Extraction Techniques using median filtering, demonstrates the superiority.

• The Korean Journal of Elementary Counseling
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• v.7 no.1
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• pp.37-66
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• 2008

This study has been carried out with the aims of developing a comprehensive inventory of peer relation problems, which is based on the Korean Inventory of Interpersonal Problems Circumplex scales (KIIP-C). It also aims to examine reliability and validity of the inventory, and provide a preliminary norms. For the current study, inventory items were culled from the following sources: the Korean Inventory of Interpersonal Problems Circumplex scales (KIIP-C), various current scales dealing with peer relations of children, and a survey of children's peer relation problems. The preliminary items for each scale were administered to 220 fourth through sixth graders. The resulting skewness of distribution, kurtosis, mean and standard deviation, item-total correlation, internal consistency, and meanings of the items were comprehensively considered in selecting the final 64 items. In order to check on reliability, internal consistency, convergence and discrimination reliability of the final items and scales, the data were collected from 1,046 fourth through sixth graders currently attending four elementary schools. The study results can be summarized as follows. Internal consistency of the inventory of peer relation problems showed the range between .70-.94 (median value of .75), split-half reliability between .67-.83 (median value of .75), and test-retest reliability between .69-.88 (median value of .81). Inter-correlation of 8 scale scores and factor analysis results of individual ipsative scores showed that the circumplex property of inventory of peer relation problems is appropriate. Regarding correlations between various existing indices and scales related to peer relation problems, both convergence reliability and discrimination reliability were found to be fair. When the scale scores for the inventory of peer relation problems compared according to the factors of gender and grade, the primary effects of gender and grade were statistically meaningful whereas effects of interaction between gender and grade were not. This study can be considered meaningful in that it constructed an inventory for a comprehensive evaluation of peer relation problems specific for children and provided preliminary norms.

• The Korean Journal of Urological Oncology
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• v.16 no.3
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• pp.126-134
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• 2018

Purpose: The purpose of this study is to compare the radiation therapy (RT) and radical prostatectomy (RP) of high-risk or locally advanced prostate cancer (PC) patients after neoadjuvant hormonal therapy (NHT). Materials and Methods: This retrospective study evaluated patients underwent RT (42 patients) or RP (152 patients) after NHT at a single center during 2003-2014. Times to biochemical recurrence (BCR), pelvic local recurrence (PLR), metastasis, clinical painful symptom progression (CPSP), castration-resistant PC (CRPC), and overall survival were compared between the RT and RP groups, after adjustment for TN stage, using the Kaplan-Meier method and log-rank test. Results: Significant inter-group differences were observed for age, Gleason score, initial PSA, and clinical and pathological T stages (all p<0.05). During a median follow-up of 71.7 months, the overall incidences of BCR, PLR, metastasis, CPSP, CRPC, and death were 49.5%, 16.5%, 8.3%, 7.7%, 7.7%, and 17.5%, respectively. The median times to BCR were 100 months for RT and 36.2 months for RP (p=0.004), although the median times were not reached for the other outcomes (all p>0.05). The independent predictor of CPSP was RP (hazard ratio, 0.291; p=0.013). Conclusions: Despite significantly different baseline parameters, RP provided better CPSP-free survival than RT among patients with localized high-risk or locally advanced PC.

• Journal of Nutrition and Health
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• v.55 no.2
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• pp.250-262
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• 2022

Purpose: Elevated iodine intake is related to a higher prevalence of subclinical hypothyroidism (SCH). We investigated the short-term effect of dietary iodine restriction on thyroid function in patients with SCH with high iodine intakes. Methods: The iodine levels in 64 SCH patients with serum TSH levels from 4.0 to 10.0 mIU/L and normal serum fT4 levels (n = 64) were assessed using 24-hour urine iodine test results and iodine intake levels calculated using a semi-quantitative food frequency questionnaire. Dietary iodine restriction was not recommended for patients with an iodine intake in the normal range (group A, n = 13), but seaweed restriction was recommended for patients with high iodine intakes (group B, n = 33). Thyroid functions and iodine levels were rechecked after three months. Another eighteen patients were prescribed thyroid hormone replacement therapy according to clinical criteria. Results: Median baseline iodine intake for the 64 patients was 290.61 ㎍/day, and median 24-hour urine iodine was 33.65 µmol/g of creatinine. The major source of dietary iodine was seaweed, which accounted for 72.2% of median baseline intake. Urine iodine and calculated iodine intake levels were positively correlated with serum TSH levels (p < 0.001 and p = 0.027, respectively), and calculated iodine intakes were significantly correlated with urine iodine levels (p = 0.001). In group B, iodine restriction significantly decreased urine iodine (p = 0.042) and TSH levels (p = 0.004), and conversion to euthyroid status was achieved in 16 of the 33 patients (48.5%). Conclusion: Iodine intake and urine iodine levels are correlated with thyroid function in SCH patients, and dietary iodine restriction can aid functional thyroid recovery in patients with elevated iodine intakes.