• Title/Summary/Keyword: Mechanisms

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Effect of metabolic imprinting on growth and development in piglets

  • Ryu, Jae-Hyoung;Lee, Yoo-Kyung;Cho, Sung-Back;Hwang, Ok-Hwa;Park, Sung-Kwon
    • Korean Journal of Agricultural Science
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    • v.43 no.1
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    • pp.72-79
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    • 2016
  • It has long been known that nutritional and environmental influences during the early developmental period affect the biological mechanisms which determine animal metabolism. This phenomenon, termed 'metabolic imprinting', can cause subtle but long-lasting responses to prenatal and postnatal nutrition and even be passed onto the next generation. A large amount of research data shows that nutrient availability, in terms of quantity as well as quality, during the early developing stages can decrease the number of newborn piglets and their body weight and increase their susceptibility to death before weaning. However, investigation of potential mechanisms of 'the metabolic imprinting' effect have been scant. Therefore, it remains unknown which factors are responsible for embryonic and early postnatal nutrition and which factors are major determinants of body weight and number of new born piglets. Intrauterine undernutrition, for example, was studied using a rat model providing dams 50% restricted nutrients during pregnancy and the results showed significant decreases in birth weight of newborns. This response may be a characteristic of a subset of modulations in embryonic development which is caused by the metabolic imprinting. Underlying mechanisms of intrauterine undernutrition and growth retardation can be explained in part by epigenetics. Epigenetics modulate animal phenotypes without changes in DNA sequences. Epigenetic modifications include DNA methylation, chromatin modification and small non-coding RNA-associated gene silencing. Precise mechanisms must be identified at the morphologic, cellular, and molecular levels by using interdisciplinary nutrigenomics approaches to increase pig production. Experimental approaches for explaining these potential mechanisms will be discussed in this review.

Exploration of Discursive-Epistemic Mechanisms in High School Earth Science Lessons (고등학교 지구과학 수업의 담화적-인식적 기제 탐색)

  • Oh, Phil Seok;Ahn, Yumin
    • Journal of the Korean earth science society
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    • v.36 no.4
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    • pp.390-403
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    • 2015
  • The purpose of this study was to explore discursive-epistemic mechanisms in high school earth science lessons. A total of 11 video recordings of earth science lessons were collected from three inservice high school teachers. The video recordings were all transcribed and analyzed by employing the discourse analysis framework used in relevant previous studies. In analysis, we identified discursive-epistemic mechanisms as functional assemblies for fulfilling particular epistemic functions in the earth science lessons. The characteristics of these mechanisms were described according to their epistemic functions. The findings of the study were compared with those of previous studies to highlight the characteristics of discursive-epistemic mechanisms in the earth science classrooms. Analyses of middle school science lessons and of science lessons in alternative forms, as well as studies using extended research methods such as indepth interviews with teachers, were suggested as implications for future research.

The Yield-Line Analysis of Reinforced Concrete Slabs Subjected to Loads of Hydrostatical Type (정수압(靜水壓) 형태(形態)의 하중(荷重)을 받는 철근(鐵筋)콘크리트 슬래브의 강복선해석(降伏線解析))

  • Oh, Jue Won;Lee, Kyu Wan
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.4 no.4
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    • pp.37-48
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    • 1984
  • The yield-line analysis is used for earring out the limit analysis of reinforced concrete slabs which are for example like those of vertical walls of tanks subjected to the loads of hydrostatical type. It is considered both isotropic and orthotropic reinforcement using the coefficient of orthotropy with different edge conditions. The yield-line analysis is carried out by using the vertical work method and four collapse mechanisms including the fan mechanisms which is more realistic than over diagonal mechanisms is considered. It is found that the fan mechanisms are more complicated than ever simple diagonal mechanisms which have used for the orthotropically reinforced concrete slabs subjected to hydrostatic pressures. Especially Horton's study is extended in this study, and they are formulated to the constrained multi-variables nonlinear optimization problems, which are solved by the Rosen-Brock Hillclimb Procedure Program and are more critical.

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Two independent mechanisms mediate discrimination of IID textures varying in mean luminance and contrast (평균밝기와 대비성의 차원으로 구성된 결 공간에서 결 분리에 작용하는 두 가지 기제)

  • 남종호
    • Korean Journal of Cognitive Science
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    • v.10 no.3
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    • pp.39-49
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    • 1999
  • The space of IID([ndependently, Identically Distributed) textures was built with axes of mean luminance and contrast, and studied on what kind of mechanisms were required to mediate texture segregation in this space. The conjecture was tested that one of these mechanisms is sensitive to the differences between the means of textures to be discriminated, whereas the other is sensitive to the differences between variances. The probability of discrimination was measured for various pairs of textures in the lID space The data were well fit by a model in which discrimination depends on two mechanisms whose responses are combined by probability summation. The conjecture was rejected that two mechanisms respectively tuned to mean and variance of texture function in segregation. Discrimination within space is mediated by 2 independent channels however: the 2 independent channels are not exactly tuned to texture mean and variance. One m mechanism was primarily sensitive to texture mean, whereas the other was sensitive to b both texture mean and variance.

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Mechanisms of thermally induced deflection of a long-span cable-stayed bridge

  • Zhou, Yi;Sun, Limin;Peng, Zhijian
    • Smart Structures and Systems
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    • v.15 no.3
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    • pp.505-522
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    • 2015
  • Variation of temperature is a primary environmental factor that affects the behavior of structures. Therefore, understanding the mechanisms of normal temperature-induced variations of structural behavior would help in distinguishing them from anomalies. In this study, we used the structural health monitoring data of the Shanghai Yangtze River Bridge, a steel girder cable-stayed bridge, to investigate the mechanisms of thermally induced vertical deflection ($D_T$) at mid-span of such bridges. The $D_T$ results from a multisource combination of thermal expansion effects of the cable temperature ($T_{Cab}$), girder temperature ($T_{Gir}$), girder differential temperature ($T_{Dif}$), and tower temperature ($T_{Tow}$). It could be approximated by multiple linear superpositions under operational conditions. The sensitivities of $D_T$ of the Shanghai Yangtze River Bridge to the above temperatures were in the following order: $T_{Cab}$ > $T_{Gir}$ > $T_{Tow}$ > $T_{Dif}$. However, the direction of the effect of $T_{Cab}$ was observed to be opposite to that of the other three temperatures, and the magnitudes of the effects of $T_{Cab}$ and $T_{Gir}$ were found to be almost one order greater than those of $T_{Dif}$ and $T_{Tow}$. The mechanisms of the thermally induced vertical deflection variation at mid-span of a cable-stayed bridge as well as the analytical methodology adopted in this study could be applicable for other long-span cable-stayed bridges.

A Comparison Study on Data Caching Policies of CCN (콘텐츠 중심 네트워킹의 데이터 캐시 정책 비교 연구)

  • Kim, Dae-Youb
    • Journal of Digital Convergence
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    • v.15 no.2
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    • pp.327-334
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    • 2017
  • For enhancing network efficiency, various applications/services like CDN and P2P try to utilize content which have previously been cached somewhere. Content-centric networking (CCN) also utilizes data caching functionality. However, dislike CDN/P2P, CCN implements such a function on network nodes. Then, any intermediated nodes can directly respond to request messages for cached data. Hence, it is essential which content is cached as well as which nodes cache transmitted content. Basically, CCN propose for every nodes on the path from the content publisher of transmitted object to a requester to cache the object. However, such an approach is inefficient considering the utilization of cached objects as well as the storage overhead of each node. Hence, various caching mechanisms are proposed to enhance the storage efficiency of a node. In this paper, we analyze the performance of such mechanisms and compare the characteristics of such mechanisms. Also, we analyze content utilization patterns and apply such pattern to caching mechanisms to analyze the practicalism of the caching mechanisms.

A STUDY ON THE DEFENSE MECHANISMS IN ADOLESCENT VICTIMS OF SCHOOL VIOLENCE (학교폭력 피해청소년의 방어기제에 관한 연구)

  • Park, Young-Sook;Shin, Jee-Yong;Jhin, Hea-Kyung
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.10 no.2
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    • pp.158-168
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    • 1999
  • This study was carried out to know the main defense mechanisms used by adolescent victims of school violence. Subjects of this study are composed of 41 adolescent victims(clinical group) and 40 normal adolescents(control group). Clinical group is divided into four subgroups of inpatient, outpatient, day hospital, and school groups. Used scales are Ewha Defense Mechanisms Test(EDMT) and Staittrait anger scale. Several important results are found. Adoescent victims use neurotic defense mechanisms of neurotic and mature level less frequently than normal adolescents. In clinical group day hospital adolescents use more mature defense mechanisms than outpatient adolescents. Displacement and acting out are correlated with trait and sate anger. Somatization is correlated with trait anger, and regression is correlated with state anger significantly.

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Performance Analysis of ATM Switch Using Dynamic Priority Control Mechanisms (동적 우선순위 제어방식을 사용한 ATM 스위치의 성능분석)

  • 박원기
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.22 no.4
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    • pp.855-869
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    • 1997
  • In this paper, we proposed two kids of dynamic priority control mechanisms controlling the cell service ratio in order to improve the QOS(Quality of Service). We also analyse theoretically the characteristics of cell loss probability and mean cell delay time by applying the proposed priority control mechanisms to ATM switch with output buffer. The proposed priority control mechanisms have the same principles of storing cells into buffer but the different principles of serving cells from buffer. The one is the control mechanism controlling the cell service ratio according to the relative cell occupancy ratio of buffer, the other is the control mechanism controlling the cell service ratio according to both the relative cell occupancy ratio of buffer and the average arrival rate. The two service classes of our concern are the delay sensitive class and the loss sensitive class. The analytical results show that the proposed control mechanisms are able to improve the QOS, the characteristics of cell loss probability and mean cell delay time, by selecting properly the relative cell occupancy ratio of buffer and the average arrival rate. conventional DLB algorithm does not support synchronous cells, but the proposed algorithm gives higher priority to synchronous cells. To reduce synchronous cell loss rate, the synchronous cell detector is used in the proposed algorithm. Synchronous cell detector detects synchronous cells, and passes them cells to the 2nd Leaky-Bucket. So it is similar to give higher priority to synchronous cells. In this paper, the proposed algorithm used audio/video traffic modeled by On/Off and Two-state MMPP, and simulated by SLAM II package. As simulation results, the proposed algorithm gets lower synchronous cell loss rate than the conventional DLB algorithms. The improved DLB algorithm for multimedia synchronization can be extended to any other cells which require higher priority.

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Collapse Initiation and Mechanisms for a Generic Multi-storey Steel Frame Subjected to Uniform and Travelling Fires

  • Rackauskaite, Egle;Kotsovinos, Panagiotis;Lange, David;Rein, Guillermo
    • International Journal of High-Rise Buildings
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    • v.10 no.4
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    • pp.265-283
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    • 2021
  • To ensure that fire induced collapse of a building is prevented it is important to understand the sequence of events that can lead to this event. In this paper, the initiation of collapse mechanisms of generic a multi-storey steel frame subjected to vertical and horizontal travelling fires are analysed computationally by tracking the formation of plastic hinges in the frame and generation of fire induced loads. Both uniform and travelling fires are considered. In total 58 different cases are analysed using finite element software LS-DYNA. For the frame examined with a simple and generic structural arrangement and higher applied fire protection to the columns, the results indicate that collapse mechanisms for singe floor and multiple floor fires can be each split into two main groups. For single floor fires (taking place in the upper floors of the frame (Group S1)), collapse is initiated by the pull-in of external columns when heated beams in end bays go into catenary action. For single floor fires occurring on the lower floors(Group S2), failure is initiated (i.e. ultimate strain of the material is exceeded) after the local beam collapse. Failure in both groups for single floor fires is governed by the generation of high loads due to restrained thermal expansion and the loss of material strength. For multiple floor fires with a low number of fire floors (1 to 3) - Group M1, failure is dominated by the loss of material strength and collapse is mainly initiated by the pull-in of external columns. For the cases with a larger number of fire floors (5 to 10) - Group M2, failure is dominated by thermal expansion and collapse is mainly initiated by swaying of the frame to the side of fire origin. The results show that for the investigated frame initiation of collapse mechanisms are affected by the fire type, the number of fire floors, and the location of the fire floor. The findings of this study could be of use to designers of buildings when developing fire protection strategies for steel framed buildings where the potential for a multifloor fire exists.

Chief Executive Officer Hubris and Corporate Social Responsibility in Korea: Moderating Role of Corporate Governance (최고경영자 휴브리스가 기업의 사회적 책임 활동 수준에 미치는 영향: 기업지배구조의 조절효과를 중심으로)

  • Park, Hyunjun;Choi, Wonyong
    • Journal of Korea Society of Industrial Information Systems
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    • v.24 no.1
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    • pp.81-94
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    • 2019
  • The corporate social responsibility has become an industry norm, and the majority of companies have adopted corporate social responsibility (CSR) activities due to institutional pressure. This paper suggests that chief executive officer (CEO) characteristics and governance mechanisms such as CEOs hubris, outside directors, and foreign ownership can influence a managerial decision of following the norm in adopting CSR. This paper argues that a CEO with hubris carry out CSR considerably less or more than a CEO without hubris because a CEO with hubris are known to have a tendency to refuse to follow the norm from institutional pressure. On the contrary, corporate governance mechanisms can guide a CEO to follow the industrial norm related to CSR because governance mechanisms tend to control CEO to reduce managerial uncertainty. The results show that CEO with hubris has a positive relationship with the degree of CSR deviation while governance mechanisms have a negative relationship. In addition, governance mechanisms negatively moderate the relationship between CEO with hubris and with the degree of CSR deviation.