• BMB Reports
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• 제28권1호
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• pp.33-39
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• 1995

The Gelatinases (typeIV collagenases) are metalloproteinases that may play an important role in tumor invasion and metastasis. Progelatinase A was purified from a conditioned medium of T98G human glioblastoma cells. TIMP-2 complexed progelatinase A and free progelatinase A were separated by heparin affinity HPLC. The final product was homogeneous on SDS-PAGE, with a molecular weight of 64,000 daltons without reduction. TIMP-2 and free progelatinase A were separated from TIMP-2 complexed progelatinase A by reverse-phase HPLC in the presence of trifluoroacetic acid. TIMP-2 complexed progelatinase A was resistant to activation by p-aminophenyl mercuric acetate (APMA), and showed less than 20% of the activity of the TIMP-2 free active enzyme. TIMP-2 free progelatinase A was easily activated to the mature form with a molecular weight of 57,000 daltons by APMA and showed high activity compared to the TIMP-2 complexed enzyme.

• Structural Engineering and Mechanics
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• 제3권2호
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• pp.107-120
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• 1995

A soil-structure interaction formulation is used here which is based on consideration of the dynamics of the structure with a free, rather than a fixed, base. This approach is shown to give a quite simple procedure for coupling the dynamic characteristics of the structure to those of the foundation and soil in order to obtain a matrix formulation for the complete system. In fixed-base studies it is common to presume that each natural mode of the structure has a given fraction of critical damping, and since the interaction formulation uses a free-base model, it seems natural for this situation to assign the equal modal damping values to free-base modes. It is shown, though, that this gives a structural model which is significantly different than the one having equal modal damping in the fixed-base modes. In particular, it is found that the damping matrix resulting in equal modal damping values for free-based modes will give a very significantly smaller damping value for the fundamental distortional mode of the fixed-base structure. Ignoring this fact could lead one to attribute dynamic effects to interaction which are actually due to the choice of damping.

• 한국광학회지
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• 제33권2호
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• pp.59-66
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• 2022

각 편광소자의 방위각을 자유롭게 제어하는 자유형 구동방식에 기반한 뮬러행렬타원계(Mueller matrix ellipsometer, MME)를 제시한다. 보정기의 위상지연각 분산특성과 전기장 투과율비의 파장의존성을 고려하여 시료에 입사하는 빛의 편광상태를 최적화하기 위한 편광자의 방위각과 편광자측 보정기의 방위각 조합들을 제시한다. 시료로부터 출사하는 빛의 스톡스상수들을 빠르고 정확하게 측정할 수 있는 검광자의 방위각과 검광자측 보정기의 방위각 조합들, 그리고 출사하는 빛의 스톡스상수들을 구하는 수학적 표현들을 제시한다. 이 MME는 이상적이지 않은 4분파장 위상지연자를 적용할 수 있도록 보정기 선택의 폭을 넓혀주므로 깊은 자외선(deep ultraviolet)부터 근적외선(near infrared)에 이르는 매우 넓은 파장 대역에 걸쳐 작동하는 뮬러행렬 분광타원계(Mueller matrix spectroscopic ellipsometer, MMSE)의 제작과 활용을 용이하게 해 줄 것이다.

• 대한토목학회논문집
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• 제11권4호
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• pp.45-54
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• 1991

선형변단면관형(線形變斷面管型) 단면(斷面) 부재(部材)의 3차원(次元) 공간(空間)에서의 고유진동해석(固有振動解析)을 위하여 회전관성(回轉慣性)도 포함하는 질량(質量) 행열(行列)을 유도하였다. 유도과정에서 정확한 변위함수(變位函數)를 사용했다. 일반적으로 많이 사용되는 변단면(變斷面) 부재(部材)의 경사(傾斜)는 매우 작으므로 '정형적분형(整形積分型)'으로 표현된 행열(行列)을 사용하여 변단면(變斷面) 부재(部材)를 포함하는 구조물을 해석할 때에 신빙성(信憑性)없는 결과를 얻게 된다. 이러한 수치적(數値的) 오류(誤謬)를 피하기 위하여 '급수형(級數型)'의 전개식(展開式)을 유도했다. 변단면(變斷面) 부재(部材)의 구조물(構造物)을 해석하기 위하여 본(本) 연구(硏究)에서 유도(誘導)된 질량(質量) 행열(行列)을 사용하여 구한 고유진동수(固有振動數)와 분할 부재(部材)를 균일단면(均一斷面) 탑형태(塔形態)로 표현하여 구한 고유진동수(固有振動數)를 비교(比較)하여 본 연구결과 효율성(效率性)과 정확성(正確性)이 증진(增進)된 것을 확인하였다.

• 한국생산제조학회지
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• 제7권6호
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• pp.117-125
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• 1998

The paper attempts to estimate the incubation time of a cavity in the interface between a power law creep particle and an elastic matrix subjected to a uniaxial stress. Since the power law creep particle is time dependent, the stresses in the interface relax. The volume free energy associated with Helmholtz free energy includes strain energies caused by applied stress and dislocations piled up in interface(DPI). The energy due to DPI is found by modifying the result of Dundurs and Mura[4]. The volume free energies caused by both applied stress and DPI are a function of the cavity size(r) and elapsed time(t) and arise from stress relaxation in the interface. Critical radius $r^*$ and incubation time $t^*$ to maximise Helmholtz free energy is found in present analysis. Also, kinetics of cavity formation are investigated using the results obtained by Riede [7]. The incubation time is defined in the analysis as the time required to satisfy both the thermodynamic and kinetic conditions. Through the analysis it is found that 1) strain energy caused by the applied stress does not contribute significantly to the thermodynamic and kinetic conditions of a cavity formation, 2) in order to satisfy both thermodynamic and kinetic conditions, critical radius $r^*$ decreases or holds constant with increase of the time until the kinetic condition(eq. 2.3) is satisfied. there for the cavity may not grow right after it is formed, as postulated by Harris [15], and Ishida and Mclean [16], 3) the effects of strain rate exponent (m), material constant $\sigma$0, volume fraction of the particle to matrix(f)and particle size on the incubation time are estimated using material constants of the copper as matrix.

• 한국측량학회지
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• 제3권2호
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• pp.48-62
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• 1985

본 논문은 g-inverse를 이용한 자유망 조정으로서, 미지 Parameter를 이용한 해법에 있어서는 모든점의 좌표가 동일경중률에 의한 Parameter로 처리되기 때문에 정규방정식의 행열이 특이행열이 된다. 이 논문은 망조정에 있어서의 특이행열과 삼변측양에 있어서 기존방법의 정확도 분석 및 삼변자유망조정의 문제를 검토하였다. 본 삼변자유망 조정의 경우에 있어서는 조정좌표의 최소제곱근 오차가 심다변망에서 35.6%, 사변망에서 50.5%로 정확도가 향상되었고, 오차구원의 요소에 있어서도 최소제곱근오차가 유심다변망에서 a=24.5%, b=5.0%, 사변망에서는 a=42.6%, b＝49.2％로 감소하였다. 따라서 자유망조정 방법의 적용은 기준점의 수평위치결정에 있어서 상대오차의 개선을 위하여 필요한 것으로 사료된다.

• Journal of applied mathematics & informatics
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• 제18권1_2호
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• pp.171-182
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• 2005

An analysis of the non-homogeneous term involved in the free surface condition for second order wave diffraction on a pair of cylinders is presented. In the computations of the nonlinear loads on offshore structures, the most challenging task is the computation of the free surface integral. The main contribution to this integrand is due to the non-homogeneous term present in the free surface condition for second order scattered potential. In this paper, the free surface condition for the second order scattered potential is derived. Under the assumption of large spacing between the two cylinders, waves scattered by one cylinder may be replaced in the vicinity of the other cylinder by equivalent plane waves together with non-planner correction terms. Then solving a complex matrix equation, the first order scattered potential is derived and since the free surface term for second order scattered potential can be expressed in terms of the first order potentials, the free surface term can be obtained using the knowledge of first order potentials only.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1993년도 봄 학술발표회논문집
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• pp.61-68
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• 1993

A computer program for free vibration analysis of plane framed structures has been developed by object oriented programming technique using C" language. The object oriented programming concepts such as object, class, method and inheritance are represented. The static and free vibration analyses for framed structures were satisfactorily performed by this program which consists of TOP, VECTOR, MATRIX, STRU, GUI and other classes. Numerical test shows the validity and capability of the present study which can be expandable to develop a general purpose object oriented finite element analysis program of structures ,res ,

• 수산해양기술연구
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• 제27권2호
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• pp.125-131
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• 1991

Electrolyte matrix fabrication process can be classifed as hot pressing, tape casting, callendering, electrophoretic deposition. however, these have limits in practice. Hot pressing is cumbersome method, because of careful heating and cooling. Furthermore, the perfected tile is so fragile that it is difficult to fit in a cell. Therefore this method is not adequate for mass production of the electrolyte matrix. Using electrophoretic deposition method, a very thin matrix can be made, but many attempts of the electrolyte embeding were found to be failure. Tape casting and callendering methods are employed in most of the matrix fabrication for the present. But these methods require lots of water as a solvent, so that coating of the LiAlO sub(2) with electrolyte is difficult. Recently, hot roll milling method has been developed and the perfected matrix was proved to be free from crack. The method, however, needs a roller to make a matrix and a perfected matrix is carefully striped off from the cooled roller. Therefore, this method requires a long time due to the cooling process. The author proposes a cold rolling process. On this method, heated slurry of the LiAlO sub(2) mixed with binder, is rolled with a cold roller. The heated slurry dose not adhere to the roller, since contacted hot slurry is rapidly solidified. Therefore fabrication speed is increased, without getting rid of merits of the hot rolling process.

• Structural Engineering and Mechanics
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• 제53권3호
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• pp.537-573
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• 2015

Multiple-step beams carrying intermediate lumped masses with/without rotary inertias are widely used in engineering applications, but in the literature for free vibration analysis of such structural systems; Bernoulli-Euler Beam Theory (BEBT) without axial force effect is used. The literature regarding the free vibration analysis of Bernoulli-Euler single-span beams carrying a number of spring-mass systems, Bernoulli-Euler multiple-step and multi-span beams carrying multiple spring-mass systems and multiple point masses are plenty, but that of Timoshenko multiple-step beams carrying intermediate lumped masses and/or rotary inertias with axial force effect is fewer. The purpose of this paper is to utilize Numerical Assembly Technique (NAT) and Differential Transform Method (DTM) to determine the exact natural frequencies and mode shapes of the axial-loaded Timoshenko multiple-step beam carrying a number of intermediate lumped masses and/or rotary inertias. The model allows analyzing the influence of the shear and axial force effects, intermediate lumped masses and rotary inertias on the free vibration analysis of the multiple-step beams by using Timoshenko Beam Theory (TBT). At first, the coefficient matrices for the intermediate lumped mass with rotary inertia, the step change in cross-section, left-end support and right-end support of the multiple-step Timoshenko beam are derived from the analytical solution. After the derivation of the coefficient matrices, NAT is used to establish the overall coefficient matrix for the whole vibrating system. Finally, equating the overall coefficient matrix to zero one determines the natural frequencies of the vibrating system and substituting the corresponding values of integration constants into the related eigenfunctions one determines the associated mode shapes. After the analytical solution, an efficient and easy mathematical technique called DTM is used to solve the differential equations of the motion. The calculated natural frequencies of Timoshenko multiple-step beam carrying intermediate lumped masses and/or rotary inertias for the different values of axial force are given in tables. The first five mode shapes are presented in graphs. The effects of axial force, intermediate lumped masses and rotary inertias on the free vibration analysis of Timoshenko multiple-step beam are investigated.