• BMB Reports
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• v.28 no.1
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• pp.33-39
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• 1995

The Gelatinases (typeIV collagenases) are metalloproteinases that may play an important role in tumor invasion and metastasis. Progelatinase A was purified from a conditioned medium of T98G human glioblastoma cells. TIMP-2 complexed progelatinase A and free progelatinase A were separated by heparin affinity HPLC. The final product was homogeneous on SDS-PAGE, with a molecular weight of 64,000 daltons without reduction. TIMP-2 and free progelatinase A were separated from TIMP-2 complexed progelatinase A by reverse-phase HPLC in the presence of trifluoroacetic acid. TIMP-2 complexed progelatinase A was resistant to activation by p-aminophenyl mercuric acetate (APMA), and showed less than 20% of the activity of the TIMP-2 free active enzyme. TIMP-2 free progelatinase A was easily activated to the mature form with a molecular weight of 57,000 daltons by APMA and showed high activity compared to the TIMP-2 complexed enzyme.

• Structural Engineering and Mechanics
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• v.3 no.2
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• pp.107-120
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• 1995

A soil-structure interaction formulation is used here which is based on consideration of the dynamics of the structure with a free, rather than a fixed, base. This approach is shown to give a quite simple procedure for coupling the dynamic characteristics of the structure to those of the foundation and soil in order to obtain a matrix formulation for the complete system. In fixed-base studies it is common to presume that each natural mode of the structure has a given fraction of critical damping, and since the interaction formulation uses a free-base model, it seems natural for this situation to assign the equal modal damping values to free-base modes. It is shown, though, that this gives a structural model which is significantly different than the one having equal modal damping in the fixed-base modes. In particular, it is found that the damping matrix resulting in equal modal damping values for free-based modes will give a very significantly smaller damping value for the fundamental distortional mode of the fixed-base structure. Ignoring this fact could lead one to attribute dynamic effects to interaction which are actually due to the choice of damping.

• Korean Journal of Optics and Photonics
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• v.33 no.2
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• pp.59-66
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• 2022

A free-form Mueller matrix ellipsometer (MME) based on independent control of the azimuthal angle of each polarizing element is introduced. The azimuthal angles of the polarizer and the matching compensator which generate the optimum Stokes vectors of an incident beam are investigated for the polarization state generator, where the spectral responses of the retardation angle and transmittance ratio of a nonideal compensator are taken into account. Similarly, the azimuthal angles of the analyzer and the corresponding compensator are investigated for the polarization-state detector, to unambiguously determine the Stokes vector of the outcoming beam from the sample, and explicit expressions for the Stokes elements are derived. Since the suggested technique enables one to utilize a nonideal quarter-wave plate as the compensator for an MME, it will contribute to the construction and application of a Mueller matrix spectroscopic ellipsometer (MMSE) operating over a wide spectral range from deep ultra-violet to near infrared.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.11 no.4
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• pp.45-54
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• 1991

The closed forms of mass matrix with rotational inertia matrix are developed for free vibration analysis in space structures containing linearing tapered members with cross section of thin-walled tube. The exact displacement functions are used for formulating mass matrix. The very small slopes of the tapered member are used in usual practice, such that the series expansion forms of these are also developed to avoid numerical failure in vibration analysis. Significant improvements of accuracy and efficiency of free vibration analysis are achieved by using the mass matrices developed in this study. Frequencies of free vibration of tapered members are compared with solutions based upon stepped representation of beam element.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.7 no.6
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• pp.117-125
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• 1998

The paper attempts to estimate the incubation time of a cavity in the interface between a power law creep particle and an elastic matrix subjected to a uniaxial stress. Since the power law creep particle is time dependent, the stresses in the interface relax. The volume free energy associated with Helmholtz free energy includes strain energies caused by applied stress and dislocations piled up in interface(DPI). The energy due to DPI is found by modifying the result of Dundurs and Mura[4]. The volume free energies caused by both applied stress and DPI are a function of the cavity size(r) and elapsed time(t) and arise from stress relaxation in the interface. Critical radius $r^*$ and incubation time $t^*$ to maximise Helmholtz free energy is found in present analysis. Also, kinetics of cavity formation are investigated using the results obtained by Riede [7]. The incubation time is defined in the analysis as the time required to satisfy both the thermodynamic and kinetic conditions. Through the analysis it is found that 1) strain energy caused by the applied stress does not contribute significantly to the thermodynamic and kinetic conditions of a cavity formation, 2) in order to satisfy both thermodynamic and kinetic conditions, critical radius $r^*$ decreases or holds constant with increase of the time until the kinetic condition(eq. 2.3) is satisfied. there for the cavity may not grow right after it is formed, as postulated by Harris [15], and Ishida and Mclean [16], 3) the effects of strain rate exponent (m), material constant $\sigma$0, volume fraction of the particle to matrix(f)and particle size on the incubation time are estimated using material constants of the copper as matrix.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.3 no.2
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• pp.48-62
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• 1985

A method for the free network adjustment is proposed, based on the application of generalized inverse matrix (g-inverse). If the network adjustment is executed according to the solution with parameters, especially when all coordinates are considered as parameters to keep unity strength, the matrix of normal equation will be singular. This paper discusses the problem of singular matrix and the analysis of accuracy between conventional method and the free network adjustment of trilateration. In case of the adjustment, the RMS errors of adjusted X, Y coordinates are increased to 35.6% in a polygon, central-point figure, and 50.5% in a quadrilateral. In the elements of error ellipse, the RMS errors are decreased by $\pm$24.5% (a) and $\pm$5.0 % (b) in the polygon, $\pm$42.6% (a) and $\pm$49.2% (b) in the quadrilateral. Introduction of free network adjustment, therefore, could be applied to improvement of relative accuracy in the horizontal positioning.

• Journal of applied mathematics & informatics
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• v.18 no.1_2
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• pp.171-182
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• 2005

An analysis of the non-homogeneous term involved in the free surface condition for second order wave diffraction on a pair of cylinders is presented. In the computations of the nonlinear loads on offshore structures, the most challenging task is the computation of the free surface integral. The main contribution to this integrand is due to the non-homogeneous term present in the free surface condition for second order scattered potential. In this paper, the free surface condition for the second order scattered potential is derived. Under the assumption of large spacing between the two cylinders, waves scattered by one cylinder may be replaced in the vicinity of the other cylinder by equivalent plane waves together with non-planner correction terms. Then solving a complex matrix equation, the first order scattered potential is derived and since the free surface term for second order scattered potential can be expressed in terms of the first order potentials, the free surface term can be obtained using the knowledge of first order potentials only.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1993.04a
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• pp.61-68
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• 1993

A computer program for free vibration analysis of plane framed structures has been developed by object oriented programming technique using C" language. The object oriented programming concepts such as object, class, method and inheritance are represented. The static and free vibration analyses for framed structures were satisfactorily performed by this program which consists of TOP, VECTOR, MATRIX, STRU, GUI and other classes. Numerical test shows the validity and capability of the present study which can be expandable to develop a general purpose object oriented finite element analysis program of structures ,res ,

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.27 no.2
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• pp.125-131
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• 1991

Electrolyte matrix fabrication process can be classifed as hot pressing, tape casting, callendering, electrophoretic deposition. however, these have limits in practice. Hot pressing is cumbersome method, because of careful heating and cooling. Furthermore, the perfected tile is so fragile that it is difficult to fit in a cell. Therefore this method is not adequate for mass production of the electrolyte matrix. Using electrophoretic deposition method, a very thin matrix can be made, but many attempts of the electrolyte embeding were found to be failure. Tape casting and callendering methods are employed in most of the matrix fabrication for the present. But these methods require lots of water as a solvent, so that coating of the LiAlO sub(2) with electrolyte is difficult. Recently, hot roll milling method has been developed and the perfected matrix was proved to be free from crack. The method, however, needs a roller to make a matrix and a perfected matrix is carefully striped off from the cooled roller. Therefore, this method requires a long time due to the cooling process. The author proposes a cold rolling process. On this method, heated slurry of the LiAlO sub(2) mixed with binder, is rolled with a cold roller. The heated slurry dose not adhere to the roller, since contacted hot slurry is rapidly solidified. Therefore fabrication speed is increased, without getting rid of merits of the hot rolling process.

• Structural Engineering and Mechanics
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• v.53 no.3
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• pp.537-573
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• 2015

Multiple-step beams carrying intermediate lumped masses with/without rotary inertias are widely used in engineering applications, but in the literature for free vibration analysis of such structural systems; Bernoulli-Euler Beam Theory (BEBT) without axial force effect is used. The literature regarding the free vibration analysis of Bernoulli-Euler single-span beams carrying a number of spring-mass systems, Bernoulli-Euler multiple-step and multi-span beams carrying multiple spring-mass systems and multiple point masses are plenty, but that of Timoshenko multiple-step beams carrying intermediate lumped masses and/or rotary inertias with axial force effect is fewer. The purpose of this paper is to utilize Numerical Assembly Technique (NAT) and Differential Transform Method (DTM) to determine the exact natural frequencies and mode shapes of the axial-loaded Timoshenko multiple-step beam carrying a number of intermediate lumped masses and/or rotary inertias. The model allows analyzing the influence of the shear and axial force effects, intermediate lumped masses and rotary inertias on the free vibration analysis of the multiple-step beams by using Timoshenko Beam Theory (TBT). At first, the coefficient matrices for the intermediate lumped mass with rotary inertia, the step change in cross-section, left-end support and right-end support of the multiple-step Timoshenko beam are derived from the analytical solution. After the derivation of the coefficient matrices, NAT is used to establish the overall coefficient matrix for the whole vibrating system. Finally, equating the overall coefficient matrix to zero one determines the natural frequencies of the vibrating system and substituting the corresponding values of integration constants into the related eigenfunctions one determines the associated mode shapes. After the analytical solution, an efficient and easy mathematical technique called DTM is used to solve the differential equations of the motion. The calculated natural frequencies of Timoshenko multiple-step beam carrying intermediate lumped masses and/or rotary inertias for the different values of axial force are given in tables. The first five mode shapes are presented in graphs. The effects of axial force, intermediate lumped masses and rotary inertias on the free vibration analysis of Timoshenko multiple-step beam are investigated.