• Title/Summary/Keyword: Massachusetts Institute of Technology

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Studying confined polymers using single-molecule DNA experiments

  • Hsieh, Chih-Chen;Doyle, Patrick S.
    • Korea-Australia Rheology Journal
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    • v.20 no.3
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    • pp.127-142
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    • 2008
  • The development of fluorescence microscopy of single-molecule DNA in the last decade has fostered a bold jump in the understanding of polymer physics. With the recent advance of nanotechnology, devices with well-defined dimensions that are smaller than typical DNA molecules can be readily manufactured. The combination of these techniques has provided an unprecedented opportunity for researchers to examine confined polymer behavior, a topic far less understood than its counterpart. Here, we review the progress reported in recent studies that investigate confined polymer dynamics by means of single-molecule DNA experiments.

A New Test Method to Determine the Initiation Time of Stress Corrosion Cracking

  • Bahn, Chi-Bum;Lee, Tae-Hyun;Lee, Seung-Gi;Choi, Hoi-Su;Kim, Ji-Hyun;Hwang, Il-Soon
    • Proceedings of the Korean Nuclear Society Conference
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    • 2005.05a
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    • pp.347-348
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    • 2005
  • A proving ring test method equipped with DCPD was developed and applied to detect the crack initiation time in PWR primary water conditions. The specimens were exposed to the PWR primary water environment during one month. The DCPD signals were very clear but the crack initiation was not detected manly because of the low stress condition. To increase the stress condition, Ni plating will be conducted after the straining the specimens.

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Bioactivities and Potential Mechanisms of Action for Conjugated Fatty Acids

  • Park, Yeon-Hwa;Pariza, Michael W.
    • Food Science and Biotechnology
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    • v.18 no.3
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    • pp.586-593
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    • 2009
  • Since conjugated linoleic acid (CLA) was identified as a principal anticancer component from ground beef in the 1980s, CLA research has discovered that CLA has a wide range of biologically beneficial effects. Clinical studies with CLA are on the rise, and it is apparent that CLA may not be as effective in humans as in rodents, in particular its anti-obesity aspect. In addition, research with regard to other conjugated fatty acids as well as CLA metabolites is still in its infancy. Investigation of bioactivities for other conjugated fatty acids and CLA metabolites may help to extend the understanding of CLA and its mechanisms of actions. This may pose an opportunity to use CLA more efficiently and expand the future use of other conjugated fatty acids as pharmacological agents to assist current treatments.

Effects of Previous History on Diffusivity and Solubility of Gas in the Polymer Matrix (이력이 고분자 재료 안으로의 확산 및 용해에 미치는 영향)

  • 윤재동;차성운;최광용;조현종
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.3
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    • pp.108-113
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    • 2000
  • An important process for making a new class of polymeric material is called microcellular plastics invented at the Massachusetts Institute of Technology. Many researches for microcellular plastics have been done in various ways and fields. But a research for the polymer which has previous history has not been tried yet. In this paper, weight gain of $CO_2$ was measured in a polymer matrix which had previous history and no history. In each case, experimental data for solubility and diffusivity was shown. A model for $CO_2$ solution process in molecular range was made. The conclusion of this paper is that the previous history has an effect on diffusivity but not solubility and the previous history made by $CO_2$ in supercritical state makes diffusivity of $CO_2$ larger.

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The ras oncogenes in aflatoxin B$_{1}$-induced rat liver carcinomas

  • Kim, Youngsoo;Min, Kyung-Rak;Gerald N.Wogan
    • The Microorganisms and Industry
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    • v.16 no.1
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    • pp.7-17
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    • 1990
  • In summary, the nature of the amino acid changes that impart oncogenicity in either the focus formation or tumorigenicity assay can be inferred by analysis of PCR-amplified DNA from tumor-derived NIH3T3 transformants and confirmed by analysis of primary liver tumors. Putative activating mutations in the c-K-ras genetic locus have been shown to involve a single-base modification of either G-C base pair at codon 12 leading to aspartate or cystein substitutions for glycine. The oncogenicity of an N-ras oncogene containing the N-ras C gene region may be related to an amino acid substitution of valine for glycine at codon 13.

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Comparison between analytic and numerical approaches to calculate screening current induced field in HTS magnet

  • Bang, Jeseok;Kim, Seokho;Kim, Jaemin;An, Soobin;Im, Chaemin;Hahn, Seungyong
    • Progress in Superconductivity and Cryogenics
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    • v.21 no.2
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    • pp.45-49
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    • 2019
  • This paper reports comparison between analytic and numerical simulation approaches for calculation of screening current and screening current induced field in a high temperature superconductor magnet. Bean slab model is adopted to calculate screening current and SCF analytically, while the finite element method numerically. A case study of screening current and SCF calculation are conducted with a magnet, a 7 T 68 mm cold-bore multi-width no-insulation GdBCO magnet built and tested by Massachusetts Institute of Technology Francis Bitter Magnet Laboratory. In this study, we assume the magnet is dunked in liquid nitrogen at 77 K. Furthermore, the simulation results are compared in terms of computation time and accuracy. Finally, discussion on the different methods together with the comparison between the calculations and experiment is provided.

Simulation Study for Engine Friction Reduction through the Enhancement of Temperature Distribution along Cylinder Liner in a Heavy Duty Diesel Engine (대형 상용 디젤 엔진의 실린더 라이너 온도 분포 개선을 통한 엔진 마찰 저감 - 해석적 연구)

  • Park, S.Y.
    • Journal of Power System Engineering
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    • v.16 no.6
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    • pp.11-18
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    • 2012
  • 대형 상용 엔진에서 발생하는 유효 도시 마력의 약 4~15%는 마찰 손실을 통해서 사라지며 마찰 손실 중 약 40~55%는 엔진 실린더와 피스톤 사이의 마찰에 의하여 발생하여, 엔진 전체에서 발생하는 마찰 손실 중 가장 많은 부분을 차지하고 있다. 이 연구에서는 엔진 실린더 라이너의 온도 분포 개선을 통해 라이너를 따라 유막을 형성하고 있는 윤활유의 적정 점성을 유지시키는 방법을 제시하고자 한다. 피스톤-라이너에서 발생하는 마찰 특성은 피스톤의 행정 위치에 따라서 접촉 마찰과 유막에 의한 마찰로 구분되며 이에 따라 요구되는 윤활유의 점성 특성 또한 달라진다. 먼저 해석 모델을 통하여 실린더 라이너 내부 온도 분포 특성을 확인한 후 피스톤 마찰 특성을 고려한 적정 온도 분포를 고찰하며 실린더 라이너에 열저항 코팅을 통해서 이를 구현하였다. 또한 실린더-피스톤 간의 마찰/윤활 해석을 통하여 열저항 코팅의 마찰 개선효과를 확인하였다.

Spectrochemical Determination of Impurities in Barium Titanate and Strontium Titanate Single Crystals (Barium Titanate 및 Strontium Titanate 單結晶中의 不純物의 分光化學分析)

  • Jae-young Hwang
    • Journal of the Korean Chemical Society
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    • v.7 no.4
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    • pp.254-256
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    • 1963
  • A spectrochemical analysis was made to compare the major impurities in $BaTiO_3$ single crystals grown from $KF-BaTiO_3$ system and $TiO_2-BaTiO_3$ system respectively. The present technique was also extended, without any modifications, to the analysis of $SrTiO_3$ crystal.

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Investigation of Self-assembly Structure and Properties of a Novel Designed Lego-type Peptide with Double Amphiphilic Surfaces

  • Wang, Liang;Zhao, Xiao-Jun
    • Bulletin of the Korean Chemical Society
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    • v.31 no.12
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    • pp.3740-3744
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    • 2010
  • A typically designed 'Peptide Lego' has two distinct surfaces: a hydrophilic side that contains the complete charge distribution and a hydrophobic side. In this article, we describe the fabrication of a unique lego-type peptide with the AEAEYAKAK sequence. The novel peptide with double amphiphilic surfaces is different from typical peptides due to special arrangement of the residues. The results of CD, FT-IR, AFM and DLS demonstrate that the peptide with the random coil characteristic was able to form stable nanostructures that were mediated by non-covalent interactions in an aqueous solution. The data further indicated that despite its different structure, the peptide was able to undergo self-assembly similar to a typical peptide. In addition, the use of hydrophobic pyrene as a model allowed the peptide to provide a new type of potential nanomaterial for drug delivery. These efforts collectively open up a new direction in the fabrication of nanomaterials that are more perfect and versatile.

MODIFICATION OF INITIALLY GROWN BN LAYERS BY POST-N$^{+}$ IMPLANTATION

  • Byon, E-S.;Lee, S-H.;Lee, S-R.;Lee, K-H.;Tian, J.;Youn, J-H.;Sung, C.
    • Journal of the Korean institute of surface engineering
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    • v.32 no.3
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    • pp.351-355
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    • 1999
  • BN films with a high content of cubic phase has been deposited by a variety of techniques. It is well known that c-BN films grow with a unique microstructure consisting of $sp^2$ and $sp^{3-}$ bonded layers. Because of existence of the initially grown $sp^{2-}$ /bonded layer, BN films are not adhesive to the substrates. In this study, post-N$^{+ }$ / implantation was applied to improve the adhesion of the films. A Monte Carlo program TAMIX was used to simulate this modification process. The simulation showed nitrogen concentration profile at $1200\AA$ in depth in case of 50keV -implantation energy. FTIR spectra of the $N^{+}$ implanted specimens demonstrated a strong change of absorption band at 1380 cm$^{ -1 }$The films were also investigated by HRTEM. From these results, it is concluded that the post ion implantation could be an effective technique which improves the adhesion between BN film and substrate.

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